Suche >
3,3-Dimethylcyclobutan-1-one
Drucken
Sie suchten nach:
155 485 results were found
3,3-Dimethylcyclobutan-1-one
Artikel-Nr:
(BOSSBS-1247R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1247R-CY3
Lokale Artikelnummer::
BOSSBS-1247R-CY3
Beschreibung:
G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors. Signaling activates a phosphatidylinositol-calcium second messenger system and generates a calcium-activated chloride current. Plays an important role in the regulation of synaptic plasticity and the modulation of the neural network activity (By similarity).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-6634R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6634R-A750
Lokale Artikelnummer::
BOSSBS-6634R-A750
Beschreibung:
Involved in global genome nucleotide excision repair (GG-NER) by acting as damage sensing and DNA-binding factor component of the XPC complex. Has only a low DNA repair activity by itself which is stimulated by RAD23B and RAD23A. Has a preference to bind DNA containing a short single-stranded segment but not to damaged oligonucleotides. This feature is proposed to be related to a dynamic sensor function: XPC can rapidly screen duplex DNA for non-hydrogen-bonded bases by forming a transient nucleoprotein intermediate complex which matures into a stable recognition complex through an intrinsic single-stranded DNA-binding activity. The XPC complex is proposed to represent the first factor bound at the sites of DNA damage and together with other core recognition factors, XPA, RPA and the TFIIH complex, is part of the pre-incision (or initial recognition) complex. The XPC complex recognises a wide spectrum of damaged DNA characterised by distortions of the DNA helix such as single-stranded loops, mismatched bubbles or single-stranded overhangs. The orientation of XPC complex binding appears to be crucial for inducing a productive NER. XPC complex is proposed to recognise and to interact with unpaired bases on the undamaged DNA strand which is followed by recruitment of the TFIIH complex and subsequent scanning for lesions in the opposite strand in a 5'-to-3' direction by the NER machinery. Cyclobutane pyrimidine dimers (CPDs) which are formed upon UV-induced DNA damage esacpe detection by the XPC complex due to a low degree of structural perurbation. Instead they are detected by the UV-DDB complex which in turn recruits and cooperates with the XPC complex in the respective DNA repair. <i>in vitro</i>, the XPC:RAD23B dimer is sufficient to initiate NER; it preferentially binds to cisplatin and UV-damaged double-stranded DNA and also binds to a variety of chemically and structurally diverse DNA adducts.
VE:
1 * 100 µl
Lieferant:
Biowest
Beschreibung:
These irrigating buffers and salt solutions are sterile, physiological balanced solutions intended for use in the maintenance of mammalian cells, where a chemically defined, balanced salt solution provides an environment that will maintain the structural and physiological integrity of cells <i>in vitro</i>. Applications include the intermediate steps for cultivation of cells, like washing, centrifugation, suspending and counting, as well as for many analytical methods or biochemical treatments. Principally these solutions should be used to keep the cells in suspension only for minutes or a few hours maximum. These buffers and solutions are not cell culture media.
Artikel-Nr:
(BOSSBS-6634R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6634R-A680
Lokale Artikelnummer::
BOSSBS-6634R-A680
Beschreibung:
Involved in global genome nucleotide excision repair (GG-NER) by acting as damage sensing and DNA-binding factor component of the XPC complex. Has only a low DNA repair activity by itself which is stimulated by RAD23B and RAD23A. Has a preference to bind DNA containing a short single-stranded segment but not to damaged oligonucleotides. This feature is proposed to be related to a dynamic sensor function: XPC can rapidly screen duplex DNA for non-hydrogen-bonded bases by forming a transient nucleoprotein intermediate complex which matures into a stable recognition complex through an intrinsic single-stranded DNA-binding activity. The XPC complex is proposed to represent the first factor bound at the sites of DNA damage and together with other core recognition factors, XPA, RPA and the TFIIH complex, is part of the pre-incision (or initial recognition) complex. The XPC complex recognises a wide spectrum of damaged DNA characterised by distortions of the DNA helix such as single-stranded loops, mismatched bubbles or single-stranded overhangs. The orientation of XPC complex binding appears to be crucial for inducing a productive NER. XPC complex is proposed to recognise and to interact with unpaired bases on the undamaged DNA strand which is followed by recruitment of the TFIIH complex and subsequent scanning for lesions in the opposite strand in a 5'-to-3' direction by the NER machinery. Cyclobutane pyrimidine dimers (CPDs) which are formed upon UV-induced DNA damage esacpe detection by the XPC complex due to a low degree of structural perurbation. Instead they are detected by the UV-DDB complex which in turn recruits and cooperates with the XPC complex in the respective DNA repair. <i>in vitro</i>, the XPC:RAD23B dimer is sufficient to initiate NER; it preferentially binds to cisplatin and UV-damaged double-stranded DNA and also binds to a variety of chemically and structurally diverse DNA adducts.
VE:
1 * 100 µl
Lieferant:
APOLLO SCIENTIFIC
Beschreibung:
1,10-Phenanthrolin Hydrochlorid Monohydrat 97%
Artikel-Nr:
(5611-02)
Lieferant:
Avantor
Lokale Artikelnummer::
BAKR5611-02
Beschreibung:
Standardized at 25 °C against chemicals whose certification is traceable to NIST. Lot standardization value accurate to ±1 part per 1000, provided on label.
VE:
1 * 1 L
Artikel-Nr:
(APOSPC7614-250MG)
Lieferant:
APOLLO SCIENTIFIC
Hersteller-Artikelnummer::
PC7614-250MG
Lokale Artikelnummer::
APOSPC7614-250MG
Beschreibung:
Methyl 3-(chlorosulphonyl)-4-phenyl-5-(trifluoromethyl)thiophene-2-carboxylate
VE:
1 * 250 mg
Lieferant:
Avantor
Beschreibung:
Salzsäure 36,5 - 38,0% NF, Multikompendial, erfüllt die analytischen Spezifikationen von BP, Ph. Eur., J.T.Baker®
Artikel-Nr:
(1.10079.0001)
Lieferant:
Merck
Hersteller-Artikelnummer::
1.10079.0001
Lokale Artikelnummer::
MERC1.10079.0001
Beschreibung:
MQuant® (MQ) Teststäbchen stellen ein Labor auf nur wenigen Quadratmillimetern dar. Als Screening-Verfahren bieten die Teststäbchen dem Anwender einen raschen Überblick darüber, ob und welche weiterführende Analysen notwendig sind. Diese gezielte Vorauswahl hilft viele zeit- und kostenaufwendige Analysen einzusparen. Die Stäbchen, die aus einer biologisch abbaubaren Polyesterfolie bestehen sowie der geringe Reagenzieninhalt in den Reaktionszonen ermöglichen eine problemlose Entsorgung.
VE:
1 * 100 Tests
Lieferant:
Thermo Scientific
Beschreibung:
Tetrachlorgold(III)säure Hydrat
Lieferant:
VWR Chemicals
Beschreibung:
TRIS HCl (Tris(hydroxymethyl)aminomethan Hydrochlorid) ≥99,0% für die biopharmazeutische Produktion
Artikel-Nr:
(BOSSBS-8544R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-8544R-A680
Lokale Artikelnummer::
BOSSBS-8544R-A680
Beschreibung:
Component of the heteropentameric receptor for GABA, the major inhibitory neurotransmitter in the vertebrate brain. Functions also as histamine receptor and mediates cellular responses to histamine. Functions as receptor for diasepines and various anesthetics, such as pentobarbital; these are bound at a separate allosteric effector binding site. Functions as ligand-gated chloride channel.
VE:
1 * 100 µl
Lieferant:
Alfa Aesar
Beschreibung:
Diammoniumtetrachloroplatinat (≥51% Pt) ≥99,9% (Metall-Basis)
Artikel-Nr:
(BOSSBS-3766R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3766R-A680
Lokale Artikelnummer::
BOSSBS-3766R-A680
Beschreibung:
Component of the heteropentameric receptor for GABA, the major inhibitory neurotransmitter in the vertebrate brain. Functions also as histamine receptor and mediates cellular responses to histamine. Functions as receptor for diazepines and various anesthetics, such as pentobarbital; these are bound at a separate allosteric effector binding site. Functions as ligand-gated chloride channel (By similarity).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3604R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3604R-CY3
Lokale Artikelnummer::
BOSSBS-3604R-CY3
Beschreibung:
WNK1 controls sodium and chloride ion transport by inhibiting the activity of WNK4, potentially by either phosphorylating the kinase or via an interaction between WNK4 and the autoinhibitory domain of WNK1. WNK4 regulates the activity of the thiazide sensitive Na/Cl cotransporter, SLC12A3, by phosphorylation. WNK1 may also play a role in actin cytoskeletal reorganization.
VE:
1 * 100 µl
Preis auf Anfrage
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Dieses Produkt kann nur an eine Lieferadresse versandt werden die über die entsprechende Lizenzen verfügt. Für weitere Hilfe bitte kontaktieren Sie Ihr VWR Vertriebszentrum.
-Additional Documentation May be needed to purchase this item. A VWR representative will contact you if needed.
Dieses Produkt wurde von Ihrer Organisation gesperrt. Bitte kontaktieren Sie Ihren Einkauf für weitere Informationen.
Dieses Produkt ist Ersatz für den von Ihnen gewünschten Artikel.
Dieses Produkt ist nicht mehr verfügbar. Bitte kontaktieren Sie den VWR Kundenservice.
|
|||||||||
Listenansicht
