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1-[2-(4-Chlorophenyl)cyclopropyl]ethan-1-one
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1-[2-(4-Chlorophenyl)cyclopropyl]ethan-1-one
Artikel-Nr:
(BOSSBS-0317R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0317R-A647
Lokale Artikelnummer::
BOSSBS-0317R-A647
Beschreibung:
Receptor-proximal protein kinase regulating integrin-mediated signal transduction. May act as a mediator of inside-out integrin signaling. Focal adhesion protein part of the complex ILK-PINCH. This complex is considered to be one of the convergence points of integrin- and growth factor-signaling pathway. Could be implicated in mediating cell architecture, adhesion to integrin substrates and anchorage-dependent growth in epithelial cells. Phosphorylates beta-1 and beta-3 integrin subunit on serine and threonine residues, but also AKT1 and GSK3B.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9577R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9577R-A350
Lokale Artikelnummer::
BOSSBS-9577R-A350
Beschreibung:
TSPEAR, also known as C21orf9, is a 669 amino acid secreted protein. Expressed as two isoforms produced by alternative splicing, TSPEAR contains one Thrombospondin N-terminal domain and seven EAR (epilepsy-associated repeat) domains. EAR domains are found in several proteins, including TSPEAR, encoded by genes that map within chromosome regions associated with seizure disorders. It is thought that the EAR domain plays a role in the pathogenesis of epilepsy by either binding to an unknown epileptic ligand or interfering with axon synaptogenesis.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-0437R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0437R-A647
Lokale Artikelnummer::
BOSSBS-0437R-A647
Beschreibung:
Streptavidin is biotin-binding protein that was originally isolated from Streptomyces avidinii. In contrast to avidin, streptavidin has no carbohydrate and has a mildly acidic pI of 5. Streptavidin products use a recombinant form of streptavidin having a mass of 53,000 daltons and a near-neutral pI. Streptavidin is a tetrameric protein, with each subunit binding one molecule of biotin with affinity similar to that of avidin. Guanidinium chloride will dissociate avidin and streptavidin into subunits, but streptavidin is more resistant to dissociation.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-4192R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-4192R-A680
Lokale Artikelnummer::
BOSSBS-4192R-A680
Beschreibung:
SLC25A20 is one of several closely related mitochondrial membrane carrier proteins that shuttle substrates between cytosol and the intramitochondrial matrix space. It mediates the transport of acylcarnitines into the mitochondrial matrix for their oxidation by the mitochondrial fatty acid oxidation pathway. Mutations in this gene are associated with carnitine acylcarnitine translocase deficiency, which can cause a variety of pathological conditions such as hypoglycemia, cardiac arrest, hepatomegaly, hepatic dysfunction and muscle weakness, and is usually lethal in new born and infants.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5713R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5713R-A680
Lokale Artikelnummer::
BOSSBS-5713R-A680
Beschreibung:
HOXA5 upregulates both p53 promoter-reporter constructs and endogenous p53 synthesis, leading to apoptosis. HOXA5 is detectable in approximately one-third of primary tumors. Lack of HOXA5 expression strongly correlates with methylation of its promoter region, suggesting a causal role for methylation in the silencing of HOXA5 gene expression. HOXA5 expression is an important step in tumorigenesis and loss of expression of p53 in human breast cancer may be primarily due to lack of expression of HOXA5.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-0437R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0437R-A555
Lokale Artikelnummer::
BOSSBS-0437R-A555
Beschreibung:
Streptavidin is biotin-binding protein that was originally isolated from Streptomyces avidinii. In contrast to avidin, streptavidin has no carbohydrate and has a mildly acidic pI of 5. Streptavidin products use a recombinant form of streptavidin having a mass of 53,000 daltons and a near-neutral pI. Streptavidin is a tetrameric protein, with each subunit binding one molecule of biotin with affinity similar to that of avidin. Guanidinium chloride will dissociate avidin and streptavidin into subunits, but streptavidin is more resistant to dissociation.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-7789R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-7789R-A750
Lokale Artikelnummer::
BOSSBS-7789R-A750
Beschreibung:
CHMP1B belongs to the chromatin-modifying protein/charged multivesicular body protein (CHMP) family. These proteins are components of ESCRT-III (endosomal sorting complex required for transport III), a complex involved in degradation of surface receptor proteins and formation of endocytic multivesicular bodies (MVBs). Some CHMPs have both nuclear and cytoplasmic/vesicular distributions, and one such CHMP, CHMP1A (MIM 164010), is required for both MVB formation and regulation of cell cycle progression
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-7789R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-7789R-A488
Lokale Artikelnummer::
BOSSBS-7789R-A488
Beschreibung:
CHMP1B belongs to the chromatin-modifying protein/charged multivesicular body protein (CHMP) family. These proteins are components of ESCRT-III (endosomal sorting complex required for transport III), a complex involved in degradation of surface receptor proteins and formation of endocytic multivesicular bodies (MVBs). Some CHMPs have both nuclear and cytoplasmic/vesicular distributions, and one such CHMP, CHMP1A (MIM 164010), is required for both MVB formation and regulation of cell cycle progression
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-4192R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-4192R-FITC
Lokale Artikelnummer::
BOSSBS-4192R-FITC
Beschreibung:
SLC25A20 is one of several closely related mitochondrial membrane carrier proteins that shuttle substrates between cytosol and the intramitochondrial matrix space. It mediates the transport of acylcarnitines into the mitochondrial matrix for their oxidation by the mitochondrial fatty acid oxidation pathway. Mutations in this gene are associated with carnitine acylcarnitine translocase deficiency, which can cause a variety of pathological conditions such as hypoglycemia, cardiac arrest, hepatomegaly, hepatic dysfunction and muscle weakness, and is usually lethal in new born and infants.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5145R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5145R-A488
Lokale Artikelnummer::
BOSSBS-5145R-A488
Beschreibung:
This gene is a member of the natriuretic peptide family and encodes a secreted protein which functions as a cardiac hormone. The protein undergoes two cleavage events, one within the cell and a second after secretion into the blood. The protein's biological actions include natriuresis, diuresis, vasorelaxation, inhibition of renin and aldosterone secretion, and a key role in cardiovascular homeostasis. A high concentration of this protein in the bloodstream is indicative of heart failure. Mutations in this gene have been associated with postmenopausal osteoporosis.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-13263R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13263R-A350
Lokale Artikelnummer::
BOSSBS-13263R-A350
Beschreibung:
This gene encodes one of several forms of glutamic acid decarboxylase, identified as a major autoantigen in insulin-dependent diabetes. The enzyme encoded is responsible for catalyzing the production of gamma aminobutyric acid from L glutamic acid. A pathogenic role for this enzyme has been identified in the human pancreas since it has been identified as an autoantibody and an autoreactive T cell target in insulin dependent diabetes. This gene may also play a role in the stiff man syndrome.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-8435R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-8435R-FITC
Lokale Artikelnummer::
BOSSBS-8435R-FITC
Beschreibung:
BXDC1 is a 306 amino acid protein encoded by the human gene BXDC1. BXDC1 is a nuclear protein that contains one Brix domain. Brix domain containing proteins represent a family of proteins involved in the biogenesis of large ribosomal subunits. The Brix domain is a region with homology to the yeast protein Pitx1 (Ribosome biogenesis protein BRX1). Pitx1 is part of a complex that includes RPF1, RPF2 and SSF1 or SSF2. This complex is required for the biogenesis of the 60S ribosomal subunit.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-10265R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-10265R-HRP
Lokale Artikelnummer::
BOSSBS-10265R-HRP
Beschreibung:
This gene is one of several genes encoding pulmonary-surfactant associated proteins (SFTPA) located on chromosome 10. Mutations in this gene and a highly similar gene located nearby, which affect the highly conserved carbohydrate recognition domain, are associated with idiopathic pulmonary fibrosis. The current version of the assembly displays only a single centromeric SFTPA gene pair rather than the two gene pairs shown in the previous assembly which were thought to have resulted from a duplication. [provided by RefSeq, Sep 2009].
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3960R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3960R-A350
Lokale Artikelnummer::
BOSSBS-3960R-A350
Beschreibung:
The NADH-ubiquinone oxidoreductase complex (complex I) of the mitochondrial respiratory chain catalyzes the transfer of electrons from NADH to ubiquinone, and consists of at least 43 subunits. The complex is located in the inner mitochondrial membrane. This gene encodes the 24 kDa subunit of complex I, and is involved in electron transfer. Mutations in this gene are implicated in Parkinson's disease, bipolar disorder, schizophrenia, and have been found in one case of early onset hypertrophic cardiomyopathy and encephalopathy. A non-transcribed pseudogene of this locus is found on chromosome 19. [provided by RefSeq, Oct 2009].
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5866R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5866R-A555
Lokale Artikelnummer::
BOSSBS-5866R-A555
Beschreibung:
Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Expression of this gene is regulated by steroid hormones and may be useful as a marker for breast cancer. An additional transcript variant has been identified, but its full length sequence has not been determined. [provided by RefSeq, Jul 2008].
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-1876R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1876R-A680
Lokale Artikelnummer::
BOSSBS-1876R-A680
Beschreibung:
The protein encoded by this gene is a member of the G-protein coupled receptor family. This protein is one of four receptors identified for prostaglandin E2 (PGE2). This receptor may have many biological functions, which involve digestion, nervous system, kidney reabsorption, and uterine contraction activities. Studies of the mouse counterpart suggest that this receptor may also mediate adrenocorticotropic hormone response as well as fever generation in response to exogenous and endogenous stimuli. Multiple transcript variants encoding different isoforms have been found for this gene.
VE:
1 * 100 µl
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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