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1-Acetyl-2-naphthol
Artikel-Nr:
(PRSI22-813)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
22-813
Lokale Artikelnummer::
PRSI22-813
Beschreibung:
Anti-H3K14ac (acetylated) Rabbit Polyclonal Antibody
VE:
1 * 50 µl
New Product
Artikel-Nr:
(PRSI22-814)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
22-814
Lokale Artikelnummer::
PRSI22-814
Beschreibung:
Anti-H3K9ac (acetylated) Rabbit Polyclonal Antibody
VE:
1 * 50 µl
New Product
Artikel-Nr:
(BOSSBS-4034R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-4034R-A555
Lokale Artikelnummer::
BOSSBS-4034R-A555
Beschreibung:
The pyruvate dehydrogenase (PDH) complex is a nuclear-encoded mitochondrial multienzyme complex that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2), and provides the primary link between glycolysis and the tricarboxylic acid (TCA) cycle. The PDH complex is composed of multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase(E3). The E1 enzyme is a heterotetramer of two alpha and two beta subunits. This gene encodes the E1 alpha 1 subunit containing the E1 active site, and plays a key role in the function of the PDH complex. Mutations in this gene are associated with pyruvate dehydrogenase E1-alpha deficiency and X-linked Leigh syndrome. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11891R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11891R-A555
Lokale Artikelnummer::
BOSSBS-11891R-A555
Beschreibung:
Myotrophin (V-1 protein) is a ubiquitously expressed cytoplasmic protein that can translocate to the nucleus during sustained NFkB activation. The gene encoding for this protein localizes to chromosome 7q33. Myotrophin may be involved in cerebellar morphogenesis and contains an acetylated N-terminus and 2.5 internal 33 amino acid ankyrin repeats. It is important in the differentiation of cerebellar neurons, particularly of granule cells. The 117 amino acid protein has been associated with, and able to induce, cardiac hypertrophy. Myotrophin increases protooncogene, ANF and Beta-Myosin heavy chain transcript levels. Myotrophin is upregulated when myocytes undergo cyclic stretch or are treated with tumor necrosis factor Alpha (TNF Alpha) or interleukin-1Beta. Highest levels of Myotrophin are detected in brain and lowest levels in skeletal muscle.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3026R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3026R-CY3
Lokale Artikelnummer::
BOSSBS-3026R-CY3
Beschreibung:
The protein encoded by this gene is a regulatory subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. This subunit may be a positive regulator of AMPK activity. The myristoylation and phosphorylation of this subunit have been shown to affect the enzyme activity and cellular localization of AMPK. This subunit may also serve as an adaptor molecule mediating the association of the AMPK complex. [provided by RefSeq, Jul 2008].
VE:
1 * 100 µl
Artikel-Nr:
(HONCR1323-2ML)
Lieferant:
Honeywell Chemicals
Hersteller-Artikelnummer::
R1323-2ML
Lokale Artikelnummer::
HONCR1323-2ML
Beschreibung:
Organic Standard, Tenuazonic acid-(acetyl-13C2) solution, 50 μg/ml in acetonitrile, Packung: Glass Bottle
VE:
1 * 2 mL
Artikel-Nr:
(PRSI22-811)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
22-811
Lokale Artikelnummer::
PRSI22-811
Beschreibung:
Anti-H3K27ac (acetylated) Rabbit Polyclonal Antibody
VE:
1 * 50 µl
New Product
Artikel-Nr:
(PRSI22-810)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
22-810
Lokale Artikelnummer::
PRSI22-810
Beschreibung:
Anti-ACTA2 (acetylated) Rabbit Polyclonal Antibody
VE:
1 * 50 µl
New Product
Artikel-Nr:
(ST1027-50)
Lieferant:
Merck Millipore (Oncogene)
Hersteller-Artikelnummer::
ST1027-50
Lokale Artikelnummer::
ONCOST1027-50
Beschreibung:
Anti-Acetylated Lysine Rabbit Polyclonal Antibody
VE:
1 * 50 µl
Artikel-Nr:
(PRSI22-809)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
22-809
Lokale Artikelnummer::
PRSI22-809
Beschreibung:
Anti-ATR (acetylated) Rabbit Polyclonal Antibody
VE:
1 * 50 µl
New Product
Artikel-Nr:
(PRSI22-815)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
22-815
Lokale Artikelnummer::
PRSI22-815
Beschreibung:
Anti-H3K56ac (acetylated) Rabbit Polyclonal Antibody
VE:
1 * 50 µl
New Product
Artikel-Nr:
(PRSI22-812)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
22-812
Lokale Artikelnummer::
PRSI22-812
Beschreibung:
Anti-H3K27ac (acetylated) Rabbit Polyclonal Antibody
VE:
1 * 50 µl
New Product
Artikel-Nr:
(EHERC10929010)
Lieferant:
EHRENSTORFER
Hersteller-Artikelnummer::
C10929010
Lokale Artikelnummer::
EHERC10929010
Beschreibung:
Ethyl butylacetylaminopropionate
VE:
1 * 0,1 g
Artikel-Nr:
(BOSSBS-8687R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-8687R-A750
Lokale Artikelnummer::
BOSSBS-8687R-A750
Beschreibung:
P53, a DNA-binding, oligomerisation domain- and transcription activation domain-containing tumor suppressor, upregulates growth arrest and apoptosis-related genes in response to stress signals, thereby influencing programmed cell death, cell differentiation, and cell cycle control mechanisms. p53 localises to the nucleus, yet can be chaperoned to the cytoplasm by the negative regulator, MDM2. MDM2 is an E3 ubiquitin ligase that is upregulated in the presence of active p53, where it poly-ubiquitinates p53 for proteasome targeting. p53 fluctuates between latent and active DNA-binding conformations and is differentially activated through posttranslational modifications, including phosphorylation and acetylation. Mutations in the DNA-binding domain (DBD) of p53, amino acids 110-286, can compromise energetically-favorable association with cis elements and are implicated in several human cancers.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-6428R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6428R
Lokale Artikelnummer::
BOSSBS-6428R
Beschreibung:
Protein phosphatase that is involved in many processes such as microtubule organization at centrosomes, maturation of spliceosomal snRNPs, apoptosis, DNA repair, tumor necrosis factor (TNF)-alpha signaling, activation of c-Jun N-terminal kinase MAPK8, regulation of histone acetylation, DNA damage checkpoint signaling, NF-kappa-B activation and cell migration. The PPP4C-PPP4R1 PP4 complex may play a role in dephosphorylation and regulation of HDAC3. The PPP4C-PPP4R2-PPP4R3A PP4 complex specifically dephosphorylates H2AFX phosphorylated on Ser-140 (gamma-H2AFX) generated during DNA replication and required for DNA double strand break repair. Dephosphorylates NDEL1 at CDK1 phosphorylation sites and negatively regulates CDK1 activity in interphase (By similarity). In response to DNA damage, catalyzes RPA2 dephosphorylation, an essential step for DNA repair since it allows the efficient RPA2-mediated recruitment of RAD51 to chromatin.
VE:
1 * 100 µl
Lieferant:
Biotium
Beschreibung:
Eukaryotic histones are basic and water-soluble nuclear proteins that form hetero-octameric nucleosome particles by wrapping 146 base pairs of DNA in a left-handed super-helical turn sequentially to form chromosomal fiber. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form the octamer; formed of two H2A-H2B dimers and two H3-H4 dimers, forming two nearly symmetrical halves by tertiary structure. Over 80% of nucleosomes contain the linker Histone H1, derived from an intronless gene that interacts with linker DNA between nucleosomes and mediates compaction into higher order chromatin. Histones are subject to posttranslational modification by enzymes primarily on their N-terminal tails, but also in their globular domains. Such modifications include methylation, citrullination, acetylation, phosphorylation, sumoylation, ubiquitination and ADP-ribosylation.
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Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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