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7-(Trifluoromethyl)-1-benzothiophene-2-carboxylic+acid
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7-(Trifluoromethyl)-1-benzothiophene-2-carboxylic+acid
Artikel-Nr:
(BOSSBS-13352R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13352R-FITC
Lokale Artikelnummer::
BOSSBS-13352R-FITC
Beschreibung:
This gene encodes a member of the gamma-glutamyl transpeptidase (GGT) family, which are important in the metabolism of glutathione. The most ubiquitously expressed human GGT gene, GGT1, encodes a single transmembrane polypeptide that is post-translationally processed to form a heavy and a light chain. In contrast, the product of this gene only contains homology to the light chain region, and lacks a transmembrane domain. Multiple alternatively spliced variants, encoding the same protein, have been identified.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-13257R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13257R-CY5
Lokale Artikelnummer::
BOSSBS-13257R-CY5
Beschreibung:
GAD-65 and GAD-67, glutamate decarboxylases function to catalyze the production of GABA (Gamma-aminobutyric acid). In the central nervous system GABA functions as the main inhibitory transmitter by increasing a Cl-conductance that inhibits neuronal firing. GABA has been shown to activate both ionotropic (GABAA) and metabotropic (GABAB) receptors as well as a third class of receptors called GABAC. Both GABAA and GABAC are ligand-gated ion channels, however, they are structurally and functionally distinct.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-12065R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12065R-A555
Lokale Artikelnummer::
BOSSBS-12065R-A555
Beschreibung:
GAD-65 and GAD-67, glutamate decarboxylases, function to catalyze the production of GABA (gamma-aminobutyric acid). In the central nervous system GABA functions as the main inhibitory transmitter by increasing a Cl- conductance that inhibits neuronal firing. GABA has been shown to activate both ionotropic (GABAA) and metabotropic (GABAB) receptors as well as a third class of receptors called GABAC. Both GABAA and GABAC are ligand-gated ion channels, however, they are structurally and functionally distinct.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-12065R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12065R-A488
Lokale Artikelnummer::
BOSSBS-12065R-A488
Beschreibung:
GAD-65 and GAD-67, glutamate decarboxylases, function to catalyze the production of GABA (gamma-aminobutyric acid). In the central nervous system GABA functions as the main inhibitory transmitter by increasing a Cl- conductance that inhibits neuronal firing. GABA has been shown to activate both ionotropic (GABAA) and metabotropic (GABAB) receptors as well as a third class of receptors called GABAC. Both GABAA and GABAC are ligand-gated ion channels, however, they are structurally and functionally distinct.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-6026R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6026R-A488
Lokale Artikelnummer::
BOSSBS-6026R-A488
Beschreibung:
Mediates homophilic cell-cell adhesion in a Ca(2+)-independent manner. Also mediates heterophilic cell-cell adhesion with CADM3 and PVRL3 in a Ca(2+)-independent manner. Acts as a tumor suppressor in non-small-cell lung cancer (NSCLC) cells. Interaction with CRTAM promotes natural killer (NK) cell cytotoxicity and interferon-gamma (IFN-gamma) secretion by CD8+ cells in vitro as well as NK cell-mediated rejection of tumors expressing CADM3 in vivo. May contribute to the less invasive phenotypes of lepidic growth tumor cells. In mast cells, may mediate attachment to and promote communication with nerves. CADM1, together with MITF, is essential for development and survival of mast cells in vivo. Acts as a synaptic cell adhesion molecule and plays a role in the formation of dendritic spines and in synapse assembly (By similarity). May be involved in neuronal migration, axon growth, pathfinding, and fasciculation on the axons of differentiating neurons. May play diverse roles in the spermatogenesis including in the adhesion of spermatocytes and spermatids to Sertoli cells and for their normal differentiation into mature spermatozoa.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-2520R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-2520R-A350
Lokale Artikelnummer::
BOSSBS-2520R-A350
Beschreibung:
Plays a role as adhesion receptor functioning by homophilic interactions and by clustering. Recruits SH2 domain-containing proteins SH2D1A/SAP. Increases proliferative responses of activated T-cells and SH2D1A/SAP does not seen be required for this process. Homophilic interactions enhance interferon gamma/IFNG secretion in lymphocytes and induce platelet stimulation via a SH2D1A/SAP-dependent pathway. May serve as a marker for hematopoietic progenitor cells.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9446R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9446R-A555
Lokale Artikelnummer::
BOSSBS-9446R-A555
Beschreibung:
AMPK is a heterotrimeric complex comprising a catalytic a subunit and regulatory b and g subunits. It protects cells from stresses that cause ATP depletion by switching off ATP-consuming biosynthetic pathways. AMPK is activated by high AMP and low ATP through a mechanism involving allosteric regulation, promotion of phosphorylation by an upstream protein kinase known as AMPK kinase and inhibition of dephosphorylation. Activated AMPK can phosphorylate and regulate in vivo hydroxy-methylglutaryl-CoA reductase and acetyl-CoA carboxylase, which are key regulatory enzymes of sterol synthesis and fatty acid synthesis, respectively. The human AMPKa1 and AMPKa2 genes encode 548 amino acid and 552 amino acid proteins, respectively. Human AMPKb1 encodes a 271 amino acid protein and human AMPKb2 encodes a 272 amino acid protein. The human AMPKg1 gene encodes a 331 amino acid protein. Human AMPKg2 and AMPKg3, which are 569 and 492 amino acid proteins, respectively, contain unique N-terminal domains and may participate directly in the binding of AMP within the AMPK complex.
VE:
1 * 100 µl
Artikel-Nr:
(PRSI36-228)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
36-228
Lokale Artikelnummer::
PRSI36-228
Beschreibung:
IDO catalyzes the first and rate-limiting step in the main pathway of human tryptophan catabolism, the kynurenine pathway. Proinflammatory mediators, such as endotoxin and IFN-gamma induce the expression of IDO in several tissues. IDO-dependent suppression of T-cell responses might function as natural immunoregulatory mechanism. Physiological IDO activity has been implicated in T-cell tolerance to tumors, dysfunctional selftolerance in non-obese diabetic (NOD) mice, and as a protective negative regulator in autoimmune disorders.
VE:
1 * 100 µG
Artikel-Nr:
(STMC100-0663)
Lieferant:
Stemcell Technologies
Hersteller-Artikelnummer::
100-0663
Lokale Artikelnummer::
STMC100-0663
Beschreibung:
The SARS-CoV-2 (NS8) Peptide pool is a lyophilised mixture of 28 peptides from non-structural protein 8 (NS8) of SARS-CoV-2. NS8 has been identified as one of the proteins exclusively conserved in a few species of the coronavirus family, and it contains Class II MHC epitopes. The pool consists of 15-mer peptides with 11-amino-acid overlaps that cover amino acids 1 to 121 on NS8.
VE:
1 * 1 KIT
 This is a MarketSource item. Additional charges may apply
Artikel-Nr:
(BOSSBS-13263R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13263R-CY3
Lokale Artikelnummer::
BOSSBS-13263R-CY3
Beschreibung:
This gene encodes one of several forms of glutamic acid decarboxylase, identified as a major autoantigen in insulin-dependent diabetes. The enzyme encoded is responsible for catalyzing the production of gamma aminobutyric acid from L glutamic acid. A pathogenic role for this enzyme has been identified in the human pancreas since it has been identified as an autoantibody and an autoreactive T cell target in insulin dependent diabetes. This gene may also play a role in the stiff man syndrome.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-13352R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13352R-A750
Lokale Artikelnummer::
BOSSBS-13352R-A750
Beschreibung:
This gene encodes a member of the gamma-glutamyl transpeptidase (GGT) family, which are important in the metabolism of glutathione. The most ubiquitously expressed human GGT gene, GGT1, encodes a single transmembrane polypeptide that is post-translationally processed to form a heavy and a light chain. In contrast, the product of this gene only contains homology to the light chain region, and lacks a transmembrane domain. Multiple alternatively spliced variants, encoding the same protein, have been identified.
VE:
1 * 100 µl
Artikel-Nr:
(ICNA0215013890)
Lieferant:
MP Biomedicals
Hersteller-Artikelnummer::
0215013890
Lokale Artikelnummer::
ICNA0215013890
Beschreibung:
A mineral oil is any of various colorless, odorless, light mixtures of alkanes in the C15 to C40 range from a non-vegetable (mineral) source, particularly a distillate of petroleum. Most often, mineral oil is a liquid by-product of the distillation of petroleum to produce gasoline and other petroleum-based products from crude oil. A mineral oil in this sense is a transparent, colorless oil composed mainly of alkanes and cyclic paraffins, related to petroleum jelly (also known as "white petrolatum").
VE:
1 * 500 mL
Artikel-Nr:
(USBI167613)
Lieferant:
US Biological
Hersteller-Artikelnummer::
167613
Lokale Artikelnummer::
USBI167613
Beschreibung:
Anti-TARP Gamma2-4-8 Mouse Monoclonal Antibody [clone: S245-36]
VE:
1 * 100 µG
Artikel-Nr:
(BOSSBS-7703R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-7703R-FITC
Lokale Artikelnummer::
BOSSBS-7703R-FITC
Beschreibung:
Involved in modulation of cell growth and cellular response to gamma radiation probably via regulation of the Akt signaling pathway. Involved in regulation of p53/TP53. Suppresses p53/TP53 protein levels and promotes its ubiquitination; the function is dependent on USP7 and independent on MDM2. Proposed to displace p53/TP53 from interaction with USP7.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-6031R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6031R-CY7
Lokale Artikelnummer::
BOSSBS-6031R-CY7
Beschreibung:
Receptor for the Fc region of complexed or aggregated immunoglobulins gamma. Low affinity receptor. Involved in a variety of effector and regulatory functions such as phagocytosis of immune complexes and modulation of antibody production by B-cells. Binding to this receptor results in down-modulation of previous state of cell activation triggered via antigen receptors on B-cells (BCR), T-cells (TCR) or via another Fc receptor. Isoform IIB1 fails to mediate endocytosis or phagocytosis. Isoform IIB2 does not trigger phagocytosis.
VE:
1 * 100 µl
Preis auf Anfrage
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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