1-Butyl-3-methylimidazolium+methyl+sulphate
Artikel-Nr:
(BOSSBS-5915R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5915R
Lokale Artikelnummer::
BOSSBS-5915R
Beschreibung:
DNA methylation, or the addition of methyl groups to cytosine bases in the dinucleotide CpG, is imperative to proper development and regulates gene expression. The methylation pattern involves the enzymatic processes of methylation and demethylation. The demethylation enzyme was recently found to be a mammalian protein, which exhibits demethylase activity associated to a methyl-CpG-binding domain (MBD). The enzyme is able to revert methylated cytosine bases to cytosines within the particular dinucleotide sequence mdCpdG by catalyzing the cleaving of the methyl group as methanol. MeCP2 and MBD1 (PCM1) are first found to repress transcription by binding specifically to methylated DNA. MBD2 and MBD4 (also known as MED1) were later found to colocalize with foci of heavily methylated satellite DNA and believed to mediate the biological functions of the methylation signal. Surprisingly, MBD3 does not bind methylated DNA both in vivo and in vitro. MBD1, MBD2, MBD3, and MBD4 are found to be expressed in somatic tissues, but the expression of MBD1 and MBD2 is reduced or absent in embryonic stem cells, which are known to be deficient in MeCP1 activity. MBD4 have homology to bacterial base excision repair DNA N-glycosylases/lyases. In some microsatellite unstable tumors MBD4 is mutated at an exonic polynucleotide tract.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5915R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5915R-A750
Lokale Artikelnummer::
BOSSBS-5915R-A750
Beschreibung:
DNA methylation, or the addition of methyl groups to cytosine bases in the dinucleotide CpG, is imperative to proper development and regulates gene expression. The methylation pattern involves the enzymatic processes of methylation and demethylation. The demethylation enzyme was recently found to be a mammalian protein, which exhibits demethylase activity associated to a methyl-CpG-binding domain (MBD). The enzyme is able to revert methylated cytosine bases to cytosines within the particular dinucleotide sequence mdCpdG by catalyzing the cleaving of the methyl group as methanol. MeCP2 and MBD1 (PCM1) are first found to repress transcription by binding specifically to methylated DNA. MBD2 and MBD4 (also known as MED1) were later found to colocalise with foci of heavily methylated satellite DNA and believed to mediate the biological functions of the methylation signal. Surprisingly, MBD3 does not bind methylated DNA both <i>in vivo</i> and <i>in vitro</i>. MBD1, MBD2, MBD3, and MBD4 are found to be expressed in somatic tissues, but the expression of MBD1 and MBD2 is reduced or absent in embryonic stem cells, which are known to be deficient in MeCP1 activity. MBD4 have homology to bacterial base excision repair DNA N-glycosylases/lyases. In some microsatellite unstable tumors MBD4 is mutated at an exonic polynucleotide tract.
VE:
1 * 100 µl
Artikel-Nr:
(APOSOR95334-25G)
Lieferant:
APOLLO SCIENTIFIC
Hersteller-Artikelnummer::
OR95334-25G
Lokale Artikelnummer::
APOSOR95334-25G
Beschreibung:
tert-Butyl N-[(2S)-1-[methoxy(methyl)amino]-3-methyl-1-oxobutan-2-yl]carbamate 25g pack 1 * 25 g
VE:
1 * 25 g
New Product
Lieferant:
MACHEREY-NAGEL
Beschreibung:
NUCLEODUR® C4 ec is a medium density monomeric butyl modified silica phase for HPLC.
Artikel-Nr:
(BOSSBS-5915R-CY5.5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5915R-CY5.5
Lokale Artikelnummer::
BOSSBS-5915R-CY5.5
Beschreibung:
DNA methylation, or the addition of methyl groups to cytosine bases in the dinucleotide CpG, is imperative to proper development and regulates gene expression. The methylation pattern involves the enzymatic processes of methylation and demethylation. The demethylation enzyme was recently found to be a mammalian protein, which exhibits demethylase activity associated to a methyl-CpG-binding domain (MBD). The enzyme is able to revert methylated cytosine bases to cytosines within the particular dinucleotide sequence mdCpdG by catalyzing the cleaving of the methyl group as methanol. MeCP2 and MBD1 (PCM1) are first found to repress transcription by binding specifically to methylated DNA. MBD2 and MBD4 (also known as MED1) were later found to colocalize with foci of heavily methylated satellite DNA and believed to mediate the biological functions of the methylation signal. Surprisingly, MBD3 does not bind methylated DNA both in vivo and in vitro. MBD1, MBD2, MBD3, and MBD4 are found to be expressed in somatic tissues, but the expression of MBD1 and MBD2 is reduced or absent in embryonic stem cells, which are known to be deficient in MeCP1 activity. MBD4 have homology to bacterial base excision repair DNA N-glycosylases/lyases. In some microsatellite unstable tumors MBD4 is mutated at an exonic polynucleotide tract.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5915R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5915R-HRP
Lokale Artikelnummer::
BOSSBS-5915R-HRP
Beschreibung:
DNA methylation, or the addition of methyl groups to cytosine bases in the dinucleotide CpG, is imperative to proper development and regulates gene expression. The methylation pattern involves the enzymatic processes of methylation and demethylation. The demethylation enzyme was recently found to be a mammalian protein, which exhibits demethylase activity associated to a methyl-CpG-binding domain (MBD). The enzyme is able to revert methylated cytosine bases to cytosines within the particular dinucleotide sequence mdCpdG by catalyzing the cleaving of the methyl group as methanol. MeCP2 and MBD1 (PCM1) are first found to repress transcription by binding specifically to methylated DNA. MBD2 and MBD4 (also known as MED1) were later found to colocalize with foci of heavily methylated satellite DNA and believed to mediate the biological functions of the methylation signal. Surprisingly, MBD3 does not bind methylated DNA both in vivo and in vitro. MBD1, MBD2, MBD3, and MBD4 are found to be expressed in somatic tissues, but the expression of MBD1 and MBD2 is reduced or absent in embryonic stem cells, which are known to be deficient in MeCP1 activity. MBD4 have homology to bacterial base excision repair DNA N-glycosylases/lyases. In some microsatellite unstable tumors MBD4 is mutated at an exonic polynucleotide tract.
VE:
1 * 100 µl
Artikel-Nr:
(APOSOR75791-25G)
Lieferant:
APOLLO SCIENTIFIC
Hersteller-Artikelnummer::
OR75791-25G
Lokale Artikelnummer::
APOSOR75791-25G
Beschreibung:
1-(tert-Butyl) 3-methyl (S)-piperidine-1,3-dicarboxylate 25g pack 1 * 25 g
VE:
1 * 25 g
New Product
Artikel-Nr:
(APOSOR91387-1G)
Lieferant:
APOLLO SCIENTIFIC
Hersteller-Artikelnummer::
OR91387-1G
Lokale Artikelnummer::
APOSOR91387-1G
Beschreibung:
tert-Butyl 5-bromo-3-methyl-1H-indazole-1-carboxylate 1g pack 1 * 1 g
VE:
1 * 1 g
New Product
Artikel-Nr:
(APOSOR74404-10G)
Lieferant:
APOLLO SCIENTIFIC
Hersteller-Artikelnummer::
OR74404-10G
Lokale Artikelnummer::
APOSOR74404-10G
Beschreibung:
(S)-tert-Butyl 3-methyl-1,4-diazepane-1-carboxylate 10g pack 1 * 10 g
VE:
1 * 10 g
New Product
Artikel-Nr:
(APOSOR74404-25G)
Lieferant:
APOLLO SCIENTIFIC
Hersteller-Artikelnummer::
OR74404-25G
Lokale Artikelnummer::
APOSOR74404-25G
Beschreibung:
(S)-tert-Butyl 3-methyl-1,4-diazepane-1-carboxylate 25g pack 1 * 25 g
VE:
1 * 25 g
New Product
Artikel-Nr:
(APOSOR1015126-100)
Lieferant:
APOLLO SCIENTIFIC
Hersteller-Artikelnummer::
OR1015126-100
Lokale Artikelnummer::
APOSOR1015126-100
Beschreibung:
Tert-Butyl (6-Hydroxyhexyl)(Methyl)Carbamate 100mg pack 1 * 100 mg
VE:
1 * 100 mg
New Product
Artikel-Nr:
(APOSOR82586-250MG)
Lieferant:
APOLLO SCIENTIFIC
Hersteller-Artikelnummer::
OR82586-250MG
Lokale Artikelnummer::
APOSOR82586-250MG
Beschreibung:
tert-Butyl 2-methyl-3-oxopyrrolidine-1-carboxylate 250mg pack 1 * 250 mg
VE:
1 * 250 mg
New Product
Artikel-Nr:
(APOSOR82836-250MG)
Lieferant:
APOLLO SCIENTIFIC
Hersteller-Artikelnummer::
OR82836-250MG
Lokale Artikelnummer::
APOSOR82836-250MG
Beschreibung:
tert-Butyl 3-methyl-4-oxopyrrolidine-1-carboxylate 250mg pack 1 * 250 mg
VE:
1 * 250 mg
New Product
Artikel-Nr:
(APOSOR80236-100G)
Lieferant:
APOLLO SCIENTIFIC
Beschreibung:
3-Butyl-1-methyl-1H-imidazol-3-ium hydroxide 100g pack 1 * 100 g
VE:
New Product
Artikel-Nr:
(APOSOR81240-1G)
Lieferant:
APOLLO SCIENTIFIC
Beschreibung:
tert-Butyl 2-bromo-1-methyl-1H-imidazole-4-carboxylate 1g pack 1 * 1 g
VE:
New Product
Artikel-Nr:
(APOSOR75065-2.5KG)
Lieferant:
APOLLO SCIENTIFIC
Hersteller-Artikelnummer::
OR75065-2.5KG
Lokale Artikelnummer::
APOSOR75065-2.5KG
Beschreibung:
2-((4-(tert-Butyl)phenoxy)methyl)oxirane 2.5kg pack 1 * 2,5 kg
VE:
1 * 2,5 kg
New Product
Preis auf Anfrage
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