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Boron+trifluoridedimethanol+complex
Artikel-Nr:
(APOSBIL3120-100ML)
Lieferant:
APOLLO SCIENTIFIC
Hersteller-Artikelnummer::
BIL3120-100ML
Lokale Artikelnummer::
APOSBIL3120-100ML
Beschreibung:
Liquid product yellow odourless pH-value 7,3 to 7,5 Boiling point 102 °C. Stabiliser for complex mixtures of biomolecules.
VE:
1 * 100 mL
Artikel-Nr:
(BOSSBS-4862R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-4862R
Lokale Artikelnummer::
BOSSBS-4862R
Beschreibung:
SORBS2 is an adapter protein that plays a role in the assembling of signaling complexes, being a link between ABL kinases and actin cytoskeleton. It can form a complex with ABL1 and CBL, thus promoting ubiquitination and degradation of ABL1 or with AKT1 and PAK1, thus mediating AKT1-mediated activation of PAK1.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9241R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9241R-CY5
Lokale Artikelnummer::
BOSSBS-9241R-CY5
Beschreibung:
E3 ubiquitin-protein ligase component of the LUBAC complex which conjugates linear ('Met-1'-linked) polyubiquitin chains to substrates and plays a key role in NF-kappa-B activation and regulation of inflammation. LUBAC conjugates linear polyubiquitin to IKBKG and RIPK1 and is involved in activation of the canonical NF-kappa-B and the JNK signaling pathways. Linear ubiquitination mediated by the LUBAC complex interferes with TNF-induced cell death and thereby prevents inflammation. LUBAC is proposed to be recruited to the TNF-R1 signaling complex (TNF-RSC) following polyubiquitination of TNF-RSC components by BIRC2 and/or BIRC3 and to conjugate linear polyubiquitin to IKBKG and possibly other components contributing to the stability of the complex. Together with FAM105B/otulin, the LUBAC complex regulates the canonical Wnt signaling during angiogenesis. Binds polyubiquitin of different linkage types.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-2987R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-2987R-A488
Lokale Artikelnummer::
BOSSBS-2987R-A488
Beschreibung:
Nuclear hormone receptor. Transcription factor that mediates the action of vitamin D3 by controlling the expression of hormone sensitive genes. Regulates transcription of hormone sensitive genes via its association with the WINAC complex, a chromatin-remodeling complex. Recruited to promoters via its interaction with the WINAC complex subunit BAZ1B/WSTF, which mediates the interaction with acetylated histones, an essential step for VDR-promoter association. Plays a central role in calcium homeostasis.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9009R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9009R-A750
Lokale Artikelnummer::
BOSSBS-9009R-A750
Beschreibung:
Transportin 1 is the beta subunit of the karyopherin receptor complex which interacts with nuclear localisation signals to target proteins to the nucleus. The karyopherin receptor complex is a heterodimer of an alpha subunit which recognises the nuclear localisation signal and a beta subunit which docks the complex at nucleoporins. Alternate splicing of this gene results in two transcript variants encoding different proteins. In cases of HIV-1 infections, transportin 1 is known to bind and mediate the nuclear import of HIV-1 Rev.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9241R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9241R-A350
Lokale Artikelnummer::
BOSSBS-9241R-A350
Beschreibung:
E3 ubiquitin-protein ligase component of the LUBAC complex which conjugates linear ('Met-1'-linked) polyubiquitin chains to substrates and plays a key role in NF-kappa-B activation and regulation of inflammation. LUBAC conjugates linear polyubiquitin to IKBKG and RIPK1 and is involved in activation of the canonical NF-kappa-B and the JNK signaling pathways. Linear ubiquitination mediated by the LUBAC complex interferes with TNF-induced cell death and thereby prevents inflammation. LUBAC is proposed to be recruited to the TNF-R1 signaling complex (TNF-RSC) following polyubiquitination of TNF-RSC components by BIRC2 and/or BIRC3 and to conjugate linear polyubiquitin to IKBKG and possibly other components contributing to the stability of the complex. Together with FAM105B/otulin, the LUBAC complex regulates the canonical Wnt signaling during angiogenesis. Binds polyubiquitin of different linkage types.
VE:
1 * 100 µl
Artikel-Nr:
(PRSI26-933)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
26-933
Lokale Artikelnummer::
PRSI26-933
Beschreibung:
CCT5 is a molecular chaperone that is member of the chaperonin containing TCP1 complex (CCT), also known as the TCP1 ring complex (TRiC). This complex consists of two identical stacked rings, each containing eight different proteins. Unfolded polypeptides enter the central cavity of the complex and are folded in an ATP-dependent manner. The complex folds various proteins, including actin and tubulin. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized.This gene encodes a molecular chaperone that is member of the chaperonin containing TCP1 complex (CCT), also known as the TCP1 ring complex (TRiC). This complex consists of two identical stacked rings, each containing eight different proteins. Unfolded polypeptides enter the central cavity of the complex and are folded in an ATP-dependent manner. The complex folds various proteins, including actin and tubulin. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
VE:
1 * 50 µG
Artikel-Nr:
(BOSSBS-4209R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-4209R-A647
Lokale Artikelnummer::
BOSSBS-4209R-A647
Beschreibung:
Cullin 2 is a member of the family of human Cullin genes (CUL1, 2, 3, 4a, 4b and 5) homologous to the S. cerevisiae cdc53 gene. It is a component of E3 ubiquitin ligase complexes, including the inactive transcriptional elongation complex SIII, which mediates the ubiquitination of hypoxia-inducible factor (HIF). SIII is formed by three subunits: Elongin C, Elongin B and VHL. Cullin 2 may serve as a rigid scaffold in the complex and may contribute to catalysis through positioning of the substrate and the ubiquitin-conjugating enzyme.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-4209R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-4209R-A350
Lokale Artikelnummer::
BOSSBS-4209R-A350
Beschreibung:
Cullin 2 is a member of the family of human Cullin genes (CUL1, 2, 3, 4a, 4b and 5) homologous to the S. cerevisiae cdc53 gene. It is a component of E3 ubiquitin ligase complexes, including the inactive transcriptional elongation complex SIII, which mediates the ubiquitination of hypoxia-inducible factor (HIF). SIII is formed by three subunits: Elongin C, Elongin B and VHL. Cullin 2 may serve as a rigid scaffold in the complex and may contribute to catalysis through positioning of the substrate and the ubiquitin-conjugating enzyme.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-4209R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-4209R-A488
Lokale Artikelnummer::
BOSSBS-4209R-A488
Beschreibung:
Cullin 2 is a member of the family of human Cullin genes (CUL1, 2, 3, 4a, 4b and 5) homologous to the S. cerevisiae cdc53 gene. It is a component of E3 ubiquitin ligase complexes, including the inactive transcriptional elongation complex SIII, which mediates the ubiquitination of hypoxia-inducible factor (HIF). SIII is formed by three subunits: Elongin C, Elongin B and VHL. Cullin 2 may serve as a rigid scaffold in the complex and may contribute to catalysis through positioning of the substrate and the ubiquitin-conjugating enzyme.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-4209R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-4209R-FITC
Lokale Artikelnummer::
BOSSBS-4209R-FITC
Beschreibung:
Cullin 2 is a member of the family of human Cullin genes (CUL1, 2, 3, 4a, 4b and 5) homologous to the S. cerevisiae cdc53 gene. It is a component of E3 ubiquitin ligase complexes, including the inactive transcriptional elongation complex SIII, which mediates the ubiquitination of hypoxia-inducible factor (HIF). SIII is formed by three subunits: Elongin C, Elongin B and VHL. Cullin 2 may serve as a rigid scaffold in the complex and may contribute to catalysis through positioning of the substrate and the ubiquitin-conjugating enzyme.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-4209R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-4209R-HRP
Lokale Artikelnummer::
BOSSBS-4209R-HRP
Beschreibung:
Cullin 2 is a member of the family of human Cullin genes (CUL1, 2, 3, 4a, 4b and 5) homologous to the S. cerevisiae cdc53 gene. It is a component of E3 ubiquitin ligase complexes, including the inactive transcriptional elongation complex SIII, which mediates the ubiquitination of hypoxia-inducible factor (HIF). SIII is formed by three subunits: Elongin C, Elongin B and VHL. Cullin 2 may serve as a rigid scaffold in the complex and may contribute to catalysis through positioning of the substrate and the ubiquitin-conjugating enzyme.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-1677R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1677R-A647
Lokale Artikelnummer::
BOSSBS-1677R-A647
Beschreibung:
Efficiently joins single-strand breaks in a double-stranded polydeoxynucleotide in an ATP-dependent reaction. Involved in DNA non-homologous end joining (NHEJ) required for double-strand break repair and V(D)J recombination. The LIG4-XRCC4 complex is responsible for the NHEJ ligation step, and XRCC4 enhances the joining activity of LIG4. Binding of the LIG4-XRCC4 complex to DNA ends is dependent on the assembly of the DNA-dependent protein kinase complex DNA-PK to these DNA ends.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-7824R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-7824R-HRP
Lokale Artikelnummer::
BOSSBS-7824R-HRP
Beschreibung:
The GINS complex is composed of four subunits, encoded by SLD5, PSF1, PSF2, and PSF3. In S. cerevisiae, it was first identified by genetic and biochemical methods to determine factors interacting with Sld5p. Genetic interactions between these four genes also suggest that they act together. The GINS complex was independently isolated in a large scale screen for cell cycle defects. A similar complex is found in Xenopus and has a ring-like structure. In yeast, all four genes are essential and cells defective in SLD5, PSF1, or PSF2 are impaired in their ability to replicate DNA. The complex localizes to origins of DNA replication and Sld5p was previously implicated as functioning in DNA replication due to its genetic interaction with DPB11. Additional genetic and biochemical interactions of the GINS complex with Dpb11p, Dpb2p, and Sld3p suggest that it functions in some way at the replication fork during DNA synthesis.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-1600R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1600R-CY7
Lokale Artikelnummer::
BOSSBS-1600R-CY7
Beschreibung:
Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the late-Golgi/trans-Golgi network (TGN) and/or endosomes. The AP complexes mediate both the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-1600R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1600R-CY5
Lokale Artikelnummer::
BOSSBS-1600R-CY5
Beschreibung:
Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the late-Golgi/trans-Golgi network (TGN) and/or endosomes. The AP complexes mediate both the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules.
VE:
1 * 100 µl
Preis auf Anfrage
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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