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1-Boc-6-brom-2-indolboronsäure
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1-Boc-6-brom-2-indolboronsäure
Artikel-Nr:
(PRSI91-653)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
91-653
Lokale Artikelnummer::
PRSI91-653
Beschreibung:
Ribonucleoside-Diphosphate Reductase Subunit M2 (RRM2) belongs to the ribonucleoside diphosphate reductase small chain family. The reductase of RRM2 catalyzes the formation of deoxyribonucleotides from ribonucleotides. Synthesis of the encoded protein (M2) is regulated in a cell-cycle dependent fashion. RRM2 supplies the precursors essential for DNA synthesis. RRM2 catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. Phosphorylation on Ser-20 relieves the inhibitory effect on Wnt signaling.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI76-352)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
76-352
Lokale Artikelnummer::
PRSI76-352
Beschreibung:
The RPA-T4 monoclonal antibody specifically binds to the CD4 receptor for the human immunodeficiency virus (HIV). CD4 is a 59 kDa single-chain transmembrane glycoprotein that expressed on the surface of most of the thymocytes, T-helper cells, and in low levels on monocytes and macrophages. CD4 is a co-receptor in the antigen-induced T cell activation, together with the MHC class II. The RPA-T4 antibody is capable of blocking HIV binding and inhibiting syncytium formation, by binding to the D1 domain of the CD4 antigen. The OKT4 and the RPA-T4 monoclonal antibodies recognize different epitopes of CD4 and they do not exhibit cross-block binding.
VE:
1 * 0,1 mg
New Product
Artikel-Nr:
(PRSI27-869)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
27-869
Lokale Artikelnummer::
PRSI27-869
Beschreibung:
UBP1 is an important SF1-independent transcriptional activator stimulating P450scc expression in human placental JEG-3 cells, whereas LBP-9 modulates the action of UBP1, exerting both positive and negative effects
VE:
1 * 50 µG
Artikel-Nr:
(PRSI49-469)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
49-469
Lokale Artikelnummer::
PRSI49-469
Beschreibung:
ASPP proteins (ASPP1, ASPP2 and iASPP) represent a new family of p53 binding proteins. ASPP1 and ASPP2 bind and enhance p53-mediated apoptosis. In contrast, the third member, iASPP, functionally inactivates p53. iASPP (also called protein phosphatase 1 regulatory (inhibitor) subunit 13 like protein, Inhibitor of ASPP protein, Protein iASPP, PPP1R13B-like protein and NFkB-interacting protein 1) plays a central role in regulation of apoptosis and transcription via its interaction with NF-kappa-B and p53/TP53 proteins. iASPP blocks transcription of HIV-1 virus by inhibiting the action of both NF-kappa-B and SP1. This protein also inhibits p53/TP53 function, possibly by preventing the association between p53/TP53 and ASPP1 or ASPP2, and therefore suppressing the subsequent activation of apoptosis. iASPP is predominantly a cytoplasmic protein (isoform 1) but can also be found in the nucleus (isoform 2). iASPP is highly expressed in heart, placenta and prostate and is weakly expressed in brain, liver, skeletal muscle, testis and peripheral blood leukocyte. The N-terminal region of isoform 1 is required for cytoplasmic localization. Defects in iASPP may be a cause of certain breast cancers and the protein is overexpressed in many patients suffering from breast carcinomas and expressing a wild-type p53/TP53 protein.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI23-158)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
23-158
Lokale Artikelnummer::
PRSI23-158
Beschreibung:
Anti-PLA2G4C Rabbit Polyclonal Antibody
VE:
1 * 50 µl
New Product
Artikel-Nr:
(PRSI25-733)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
25-733
Lokale Artikelnummer::
PRSI25-733
Beschreibung:
CSHL1 is a member of the somatotropin/prolactin family of hormones which play an important role in growth control. This particular family member is expressed in placental villi, although it was originally thought to be a pseudogene. In fact, alternative splicing suggests that the majority of the transcripts would be unable to express a secreted protein.The protein encoded by this gene is a member of the somatotropin/prolactin family of hormones which play an important role in growth control. The gene, along with four other related genes, is located at the growth hormone locus on chromosome 17 where they are interspersed in the same transcriptional orientation; an arrangement which is thought to have evolved by a series of gene duplications. Although the five genes share a remarkably high degree of sequence identity, they are expressed selectively in different tissues. This particular family member is expressed in placental villi, although it was originally thought to be a pseudogene. In fact, alternative splicing suggests that the majority of the transcripts would be unable to express a secreted protein. Alternatively spliced transcript variants encoding different isoforms have been identified.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI46-358)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
46-358
Lokale Artikelnummer::
PRSI46-358
Beschreibung:
Anti-SERPINB6 Goat Polyclonal Antibody
VE:
1 * 100 µG
Artikel-Nr:
(PRSI42-918)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
42-918
Lokale Artikelnummer::
PRSI42-918
Beschreibung:
Anti-CHIT1 Goat Polyclonal Antibody
VE:
1 * 100 µG
Artikel-Nr:
(PRSI6547)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
6547
Lokale Artikelnummer::
PRSI6547
Beschreibung:
SLC35D3 Antibody: The solute carrier family SLC35 consists of at least 17 proteins that act as nucleotide sugar transporters localized to the Golgi apparatus and endoplasmic reticulum. The novel protein SLC35D3 is highly homologous to SLC35D1 and SLC35D2, both of which transport UDP-glucuronic acid and UDP-N-acetylgalactosamine, suggesting that SLC35D3 is also involved in the transport of nucleotide sugars. It has been suggested that SLC35D3 regulates platelet dense granules, lysosome-related organelles which contain high concentrations of several biologically important low molecular weight molecules necessary for normal blood homeostasis.
VE:
1 * 100 µG
Artikel-Nr:
(PRSI22-483)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
22-483
Lokale Artikelnummer::
PRSI22-483
Beschreibung:
Anti-UFD1L Rabbit Polyclonal Antibody
VE:
1 * 50 µl
New Product
Artikel-Nr:
(PRSI5691P)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
5691P
Lokale Artikelnummer::
PRSI5691P
Beschreibung:
CCDC69 peptide is used for blocking the activity of CCDC69 antibody.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI79-551)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
79-551
Lokale Artikelnummer::
PRSI79-551
Beschreibung:
Converts transient diacylglycerol (DAG) signals into prolonged physiological effects, downstream of PKC. Involved in resistance to oxidative stress through activation of NF-κ-B.
VE:
1 * 100 µG
Artikel-Nr:
(PRSI29-776)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
29-776
Lokale Artikelnummer::
PRSI29-776
Beschreibung:
DCUN1D1 may contribute to neddylation of cullin components of SCF-type E3 ubiquitin ligase complexes. Neddylation of cullins play an essential role in the regulation of SCF-type complexes activity.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI26-536)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
26-536
Lokale Artikelnummer::
PRSI26-536
Beschreibung:
The exact function of LOC643641 remains unknown.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI26-515)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
26-515
Lokale Artikelnummer::
PRSI26-515
Beschreibung:
SPOP may modulate the transcriptional repression activities of death-associated protein 6 (DAXX), which interacts with histone deacetylase, core histones, and other histone-associated proteins. In mouse, the protein binds to the putative leucine zipper domain of macroH2A1.2, a variant H2A histone that is enriched on inactivated X chromosomes. The BTB/POZ domain of this protein has been shown in other proteins to mediate transcriptional repression and to interact with components of histone deacetylase co-repressor complexes. This gene encodes a protein that may modulate the transcriptional repression activities of death-associated protein 6 (DAXX), which interacts with histone deacetylase, core histones, and other histone-associated proteins. In mouse, the encoded protein binds to the putative leucine zipper domain of macroH2A1.2, a variant H2A histone that is enriched on inactivated X chromosomes. The BTB/POZ domain of this protein has been shown in other proteins to mediate transcriptional repression and to interact with components of histone deacetylase co-repressor complexes. Alternative splicing of this gene results in multiple transcript variants encoding the same protein.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI27-159)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
27-159
Lokale Artikelnummer::
PRSI27-159
Beschreibung:
MUC3B is major glycoprotein component of a variety of mucus gels. It is thought to provide a protective, lubricating barrier against particles and infectious agents at mucosal surfaces.
VE:
1 * 50 µG
Preis auf Anfrage
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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