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2-Brom-5-fluorisonicotins\u00E4ure
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2-Brom-5-fluorisonicotins\u00E4ure
Artikel-Nr:
(PRSI60-743)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
60-743
Lokale Artikelnummer::
PRSI60-743
Beschreibung:
For WB starting dilution is: 1:1000.
VE:
1 * 400 µl
New Product
Artikel-Nr:
(PRSI92-656)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
92-656
Lokale Artikelnummer::
PRSI92-656
Beschreibung:
T cell immunoglobulin and mucin domain-3 (TIM3), also called hepatitis A virus cellular receptor 2 (HAVCR2), is a transmembrane glycoprotein of the TIM family of immune regulating molecules and plays an important role in the Th1-mediated immune response. TIM3 is expressed on the Th1 cells, CD8 T-cells, monocytes, and dendritic cells, but not on Th2 cells. TIM3 expressed by monocytes and dendritic cells facilitates phagocytosis of apoptotic cells and up-regulates cross-presentation of apoptotic cell-associated antigens through interaction with phosphatidylserine. Engagement of TIM3 by its ligand galectin-9 induces a range of immunosuppressive functions which enhance immune tolerance and inhibit anti-tumour immunity. Stimulation of TIM3 with an agonistic antibody promotes inflammation through the activation of innate immune cells. TIM3 is also regarded as a potential target molecule for immunotherapy. TIM3 and programmed cell death 1 (PD-1) as two important coinhibitory regulators of T cell responses, have been implicated with the T-cell dysfunction or exhaustion associated with chronic HBV infection including HBV-related HCC.
VE:
1 * 50 µG
Artikel-Nr:
(PRSIPM-4821)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
PM-4821
Lokale Artikelnummer::
PRSIPM-4821
Beschreibung:
Bim Monoclonal Antibody: Members in the Bcl-2 family are critical regulators of apoptosis by either inhibiting or promoting cell death. Bcl-2 homology 3 (BH3) domain is a potent death domain. BH3 domain containing pro-apoptotic proteins, including Bad, Bax, Bid, Bik, and Hrk, form a growing subclass of the Bcl-2 family. Bim is another BH3 domain containing protein which can induce apoptosis. Bim interacts with diverse members in the pro-survival Bcl-2 sub-family including Bcl-2, Bcl-xL and Bcl-w. The messenger RNA of Bim is ubiquitously expressed in multiple tissues and cell lines.
VE:
1 * 100 µG
Artikel-Nr:
(PRSI19-366)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
19-366
Lokale Artikelnummer::
PRSI19-366
Beschreibung:
Anti-CRTAP Rabbit Polyclonal Antibody
VE:
1 * 50 µl
New Product
Artikel-Nr:
(PRSI29-720)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
29-720
Lokale Artikelnummer::
PRSI29-720
Beschreibung:
Zeta-globin is an alpha-like hemoglobin. The zeta-globin polypeptide is synthesized in the yolk sac of the early embryo, while alpha-globin is produced throughout fetal and adult like. The zeta-globin gene is a member of the human alpha-globin gene cluster that includes five functional genes and two pseudogenes. The order of genes is: 5' - zeta - pseudozeta - mu - pseudoalpha-1 -alpha-2 -alpha-1 - theta1 - 3'.Zeta-globin (HBZ ) is an alpha-like hemoglobin. The zeta-globin polypeptide is synthesized in the yolk sac of the early embryo, while alpha-globin is produced throughout fetal and adult like. The zeta-globin gene is a member of the human alpha-globin gene cluster that involves 4 functional genes and 3 nonfunctional pseudogenes. The order of genes is: 5'-zeta -- pseudozeta -- pseudoalpha2 -- pseudoalpha1 --alpha2 -- alph1 -- theta1-3'.
VE:
1 * 100 µG
Artikel-Nr:
(PRSI26-527)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
26-527
Lokale Artikelnummer::
PRSI26-527
Beschreibung:
PHF12 acts as a transcriptional repressor. It is involved in recruitment of functional SIN3A complexes to DNA. PHF12 represses transcription at least in part through the activity of an associated histone deacetylase (HDAC). IT may also repress transcription in a SIN3A-independent manner through recruitment of functional AES complexes to DNA.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI45-518)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
45-518
Lokale Artikelnummer::
PRSI45-518
Beschreibung:
Anti-UBR5 Goat Polyclonal Antibody
VE:
1 * 100 µG
Artikel-Nr:
(PRSI49-331)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
49-331
Lokale Artikelnummer::
PRSI49-331
Beschreibung:
Cbl-c is also known as signal transduction protein CBL-C, SH3-binding protein CBL-C, CBL-3, and RING finger protein 57. Cbl proteins are a family of ubiquitin protein ligases (E3s) that negatively regulate signaling by targeting activated tyrosine kinases for degradation. Cbl-c (a.k.a. Cbl-3) is the most recently cloned member of the Cbl proteins and is expressed only in epithelial cells (the other Cbl proteins are ubiquitously expressed). Cbl-c, like the other mammalian Cbl proteins, can ubiquitinate the activated EGFR and target it for degradation. Cbl-c knock out mice show no obvious phenotype. Thus, the physiological role of Cbl-c is not known.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI5683)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
5683
Lokale Artikelnummer::
PRSI5683
Beschreibung:
TMEM184B Antibody: TMEM184B, also known as C22orf5, is a 407 amino acid multi-pass membrane protein and represents a novel gene in the activation of the MAPK signaling pathway. The gene encoding TMEM184B maps to human chromosome 22; mutations in several of the genes in chromosome 22 are involved in the development of autism, schizophrenia, Phelan-McDermid syndrome and Neurofibromatosis type 2, suggesting that TMEM184B may play a role in these syndromes.
VE:
1 * 100 µG
Artikel-Nr:
(PRSI61-718)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
61-718
Lokale Artikelnummer::
PRSI61-718
Beschreibung:
For WB starting dilution is: 1:1000.
VE:
1 * 400 µl
New Product
Artikel-Nr:
(PRSI6679)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
6679
Lokale Artikelnummer::
PRSI6679
Beschreibung:
MYBPC1 Antibody: Myosin binding protein C (MYBPC) is a component of the thick filament of striated muscle, with the slow-type isoform designated MYBPC1. Both the fast-type (MYBPC2) and slow-type MYBPC protein contains seven immunoglobulin C2 motifs and three fibronectin type-III repeats. Multiple isoforms of MYBPC1 are known to exist, and are present in varying amounts in different skeletal muscles. It is thought that the MYBPC1 slow subfamily may play important roles in the assembly and stabilization of sarcomeric M- and A-bands and regulate the contractile properties of the actomyosin filaments.
VE:
1 * 100 µG
Artikel-Nr:
(PRSI26-620)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
26-620
Lokale Artikelnummer::
PRSI26-620
Beschreibung:
The exact function of FAM78B remains unknown.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI4949P)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
4949P
Lokale Artikelnummer::
PRSI4949P
Beschreibung:
TOM70 peptide is used for blocking the activity of TOM70 antibody.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI4267P)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
4267P
Lokale Artikelnummer::
PRSI4267P
Beschreibung:
Carabin peptide is used for blocking the activity of Carabin antibody.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI36-070)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
36-070
Lokale Artikelnummer::
PRSI36-070
Beschreibung:
DLK1 (Protein delta homolog 1; Preadipocyte factor 1; Pref-1) is a regulator of adipocyte differentiation found in serum and urine. DLK1 might be a decoy ligand. Serum or plasma levels of soluble DLK1 affect negatively or positively adipogenesis and control mesenchymal cell fate. DLK1 is frequently upregulated in myelodysplastic syndrome (MDS) patients compared to non-leukemic individuals.
VE:
1 * 100 µG
Artikel-Nr:
(PRSI29-160)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
29-160
Lokale Artikelnummer::
PRSI29-160
Beschreibung:
ZNF548 belongs to the krueppel C2H2-type zinc-finger protein family. It contains 11 C2H2-type zinc fingers and 1 KRAB domain. ZNF548 may be involved in transcriptional regulation.
VE:
1 * 50 µG
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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