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5-Chlor-2-methyl-3-nitrophenylboronsäure
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5-Chlor-2-methyl-3-nitrophenylboronsäure
Artikel-Nr:
(1294987.)
Lieferant:
USP
Hersteller-Artikelnummer::
1294987
Lokale Artikelnummer::
USPH1294987
Beschreibung:
USP Reference Standards are specified for use in conducting official USP–NF tests and assays. USP also provides Reference Standards specified in the Food Chemicals Codex as well as authentic substances—high-quality chemical samples—as a service to analytical, clinical, pharmaceutical and research laboratories. To confirm accuracy and reproducibility, USP Reference Standards are rigorously tested and evaluated by multiple independent laboratories including USP, commercial, regulatory, and academic labs. USP also provide publicly available, official documentary standards for pharmaceutical ingredients in the USP–NF that link directly with our primary reference standards.
VE:
1 * 100 mg
Artikel-Nr:
(217-0803)
Lieferant:
DWK Life Sciences
Hersteller-Artikelnummer::
286126609
Lokale Artikelnummer::
SCOT286126609
Beschreibung:
DURAN®, borosilicate glass 3.3, clear.
VE:
1 * 1 ST
Lieferant:
Sigma-Aldrich
Beschreibung:
Azelainsäure, Sigma-Aldrich®
Lieferant:
Sigma-Aldrich
Beschreibung:
Azelainsäure, Sigma-Aldrich®
Artikel-Nr:
(BOSSBS-8444R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-8444R-A350
Lokale Artikelnummer::
BOSSBS-8444R-A350
Beschreibung:
This gene encodes a nuclear phosphoprotein that plays a role in maintaining genomic stability, and it also acts as a tumor suppressor. The encoded protein combines with other tumor suppressors, DNA damage sensors, and signal transducers to form a large multi-subunit protein complex known as the BRCA1-associated genome surveillance complex (BASC). This gene product associates with RNA polymerase II, and through the C-terminal domain, also interacts with histone deacetylase complexes. This protein thus plays a role in transcription, DNA repair of double-stranded breaks, and recombination. Mutations in this gene are responsible for approximately 40% of inherited breast cancers and more than 80% of inherited breast and ovarian cancers. Alternative splicing plays a role in modulating the subcellular localization and physiological function of this gene. Many alternatively spliced transcript variants, some of which are disease-associated mutations, have been described for this gene, but the full-length natures of only some of these variants has been described. A related pseudogene, which is also located on chromosome 17, has been identified. [provided by RefSeq, May 2009].
VE:
1 * 100 µl
Lieferant:
Biotium
Beschreibung:
Tumor Necrosis Factor Alpha (TNF alpha) is a protein secreted by lipopolysaccharide-stimulated macrophages, and causes tumor necrosis when injected into tumor bearing mice. TNF alpha is believed to mediate pathogenic shock and tissue injury associated with endotoxemia. TNF alpha exists as a multimer of two, three, or five non-covalently linked units, but shows a single 17 kDa band following SDS PAGE under non-reducing conditions. TNF alpha is closely related to the 25 kDa protein Tumor Necrosis Factor beta (lymphotoxin), sharing the same receptors and cellular actions. TNF alpha causes cytolysis of certain transformed cells, being synergistic with interferon gamma in its cytotoxicity. Although it has little effect on many cultured normal human cells, TNF alpha appears to be directly toxic to vascular endothelial cells. Other actions of TNF alpha include stimulating growth of human fibroblasts and other cell lines, activating polymorphonuclear neutrophils and osteoclasts, and induction of interleukin 1, prostaglandin E2 and collagenase production.
Artikel-Nr:
(BOSSBS-5221R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5221R-A350
Lokale Artikelnummer::
BOSSBS-5221R-A350
Beschreibung:
This gene encodes a nuclear phosphoprotein that plays a role in maintaining genomic stability, and it also acts as a tumor suppressor. The encoded protein combines with other tumor suppressors, DNA damage sensors, and signal transducers to form a large multi-subunit protein complex known as the BRCA1-associated genome surveillance complex (BASC). This gene product associates with RNA polymerase II, and through the C-terminal domain, also interacts with histone deacetylase complexes. This protein thus plays a role in transcription, DNA repair of double-stranded breaks, and recombination. Mutations in this gene are responsible for approximately 40% of inherited breast cancers and more than 80% of inherited breast and ovarian cancers. Alternative splicing plays a role in modulating the subcellular localization and physiological function of this gene. Many alternatively spliced transcript variants, some of which are disease-associated mutations, have been described for this gene, but the full-length natures of only some of these variants has been described. A related pseudogene, which is also located on chromosome 17, has been identified. [provided by RefSeq, May 2009].
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-8444R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-8444R-A488
Lokale Artikelnummer::
BOSSBS-8444R-A488
Beschreibung:
This gene encodes a nuclear phosphoprotein that plays a role in maintaining genomic stability, and it also acts as a tumor suppressor. The encoded protein combines with other tumor suppressors, DNA damage sensors, and signal transducers to form a large multi-subunit protein complex known as the BRCA1-associated genome surveillance complex (BASC). This gene product associates with RNA polymerase II, and through the C-terminal domain, also interacts with histone deacetylase complexes. This protein thus plays a role in transcription, DNA repair of double-stranded breaks, and recombination. Mutations in this gene are responsible for approximately 40% of inherited breast cancers and more than 80% of inherited breast and ovarian cancers. Alternative splicing plays a role in modulating the subcellular localization and physiological function of this gene. Many alternatively spliced transcript variants, some of which are disease-associated mutations, have been described for this gene, but the full-length natures of only some of these variants has been described. A related pseudogene, which is also located on chromosome 17, has been identified. [provided by RefSeq, May 2009].
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9162R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9162R-CY5
Lokale Artikelnummer::
BOSSBS-9162R-CY5
Beschreibung:
The tripartite motif (TRIM) family of proteins are characterized by a conserved TRIM domain that includes a coiled-coil region, a B-box type zinc finger, one RING finger and three zinc-binding domains. TRIM17 (tripartite motif-containing 17), also known as RBCC, terf or RNF16, is a 477 amino acid protein that contains one RING-type zinc finger, one SPRY domain and one B box-type zinc finger. Expressed nearly exclusively in testis, TRIM17 belongs to the TRIM family and, based on its functional domains, may play a role in transcriptional regulation events. The gene encoding TRIM17 maps to human chromosome 1, which spans 260 million base pairs, contains over 3,000 genes and comprises nearly 8% of the human genome. Chromosome 1 houses a large number of disease-associated genes, including those that are involved in familial adenomatous polyposis, Stickler syndrome, Parkinson’s disease, Gaucher disease, schizophrenia and Usher syndrome. Aberrations in chromosome 1 are found in a variety of cancers, including head and neck cancer, malignant melanoma and multiple myeloma
VE:
1 * 100 µl
Artikel-Nr:
(PRSI4979P)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
4979P
Lokale Artikelnummer::
PRSI4979P
Beschreibung:
RNAse H2A peptide is used for blocking the activity of RNAse H2A antibody.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI2117P)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
2117P
Lokale Artikelnummer::
PRSI2117P
Beschreibung:
IKK alpha peptide is used for blocking the activity of IKK alpha antibody.
VE:
1 * 50 µG
Artikel-Nr:
(KGWA17219)
Lieferant:
KGW
Hersteller-Artikelnummer::
17219
Lokale Artikelnummer::
KGWA17219
Beschreibung:
Cryogenic storage vessel, Deckel für Typ 17 C
VE:
1 * 1 ST
Artikel-Nr:
(BOSSBSM-1240M-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BSM-1240M-A680
Lokale Artikelnummer::
BOSSBSM-1240M-A680
Beschreibung:
Fibrinogen is the main protein of blood coagulation system. It is a large protein and it consists of two identical subunits that contain three polypeptide chains: alpha, beta and gamma. All chains are connected with each other by a number of disulfide bonds. Fibrinopeptides A (1 to 16 amino acids) and B (1 to 17 amino acids) are released by thrombin from the N terminal parts of alpha and beta chains, respectively. In this way fibrinogen is converted into fibrin, which by means of polymerisation forms a fibrin clot. Fibrinogen clotting underlies pathogenesis of MI, thromboembolism and thromboses of arteries and veins, Zince fibrin is the main substrate for thrombus formation. Fibrinogen activation is also involved in pathogenesis of inflammation, tumor growth and many other diseases. The normal fibrinogen concentration in plasma is about 3 mg/ml. The elevated level of fibrinogen in patient's blood is regarded as an independent risk factor for cardiovascular diseases. An increase in blood fibrinogen concentration was shown to be a strong predictor of coronary heart disease. All these facts make fibrinogen an important parameter in the diagnosis of cardiovascular diseases.
VE:
1 * 100 µl
Artikel-Nr:
(BOCH12134)
Lieferant:
BOCHEM
Hersteller-Artikelnummer::
12134
Lokale Artikelnummer::
BOCH12134
Beschreibung:
Tubing clamps made of stainless steel.
VE:
1 * 1 ST
Artikel-Nr:
(BOSSBS-5221R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5221R-A750
Lokale Artikelnummer::
BOSSBS-5221R-A750
Beschreibung:
This gene encodes a nuclear phosphoprotein that plays a role in maintaining genomic stability, and it also acts as a tumor suppressor. The encoded protein combines with other tumor suppressors, DNA damage sensors, and signal transducers to form a large multi-subunit protein complex known as the BRCA1-associated genome surveillance complex (BASC). This gene product associates with RNA polymerase II, and through the C-terminal domain, also interacts with histone deacetylase complexes. This protein thus plays a role in transcription, DNA repair of double-stranded breaks, and recombination. Mutations in this gene are responsible for approximately 40% of inherited breast cancers and more than 80% of inherited breast and ovarian cancers. Alternative splicing plays a role in modulating the subcellular localization and physiological function of this gene. Many alternatively spliced transcript variants, some of which are disease-associated mutations, have been described for this gene, but the full-length natures of only some of these variants has been described. A related pseudogene, which is also located on chromosome 17, has been identified.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-10361R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-10361R-CY3
Lokale Artikelnummer::
BOSSBS-10361R-CY3
Beschreibung:
Fibrinogen is the main protein of blood coagulation system. It is a large protein and it consists of two identical subunits that contain three polypeptide chains: alpha, beta and gamma. All chains are connected with each other by a number of disulfide bonds. Fibrinopeptides A (1 to 16 amino acids) and B (1 to 17 amino acids) are released by thrombin from the N terminal parts of alpha and beta chains, respectively. In this way fibrinogen is converted into fibrin, which by means of polymerization forms a fibrin clot. Fibrinogen clotting underlies pathogenesis of MI, thromboembolism and thromboses of arteries and veins, since fibrin is the main substrate for thrombus formation. Fibrinogen activation is also involved in pathogenesis of inflammation, tumor growth and many other diseases. The normal fibrinogen concentration in plasma is about 3 mg/ml. The elevated level of fibrinogen in patient's blood is regarded as an independent risk factor for cardiovascular diseases. An increase in blood fibrinogen concentration was shown to be a strong predictor of coronary heart disease (Sonel A. et al, and Rapold H.J. et al). All these facts make fibrinogen an important parameter in the diagnosis of cardiovascular diseases.
VE:
1 * 100 µl
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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