17-Octadecinsäure
Lieferant:
Biotium
Beschreibung:
Tumor Necrosis Factor Alpha (TNF alpha) is a protein secreted by lipopolysaccharide-stimulated macrophages, and causes tumor necrosis when injected into tumor bearing mice. TNF alpha is believed to mediate pathogenic shock and tissue injury associated with endotoxemia. TNF alpha exists as a multimer of two, three, or five non-covalently linked units, but shows a single 17 kDa band following SDS PAGE under non-reducing conditions. TNF alpha is closely related to the 25 kDa protein Tumor Necrosis Factor beta (lymphotoxin), sharing the same receptors and cellular actions. TNF alpha causes cytolysis of certain transformed cells, being synergistic with interferon gamma in its cytotoxicity. Although it has little effect on many cultured normal human cells, TNF alpha appears to be directly toxic to vascular endothelial cells. Other actions of TNF alpha include stimulating growth of human fibroblasts and other cell lines, activating polymorphonuclear neutrophils and osteoclasts, and induction of interleukin 1, prostaglandin E2 and collagenase production. TNF alpha is currently being evaluated in treatment of certain cancers and AIDS Related Complex.
Lieferant:
Sigma-Aldrich
Beschreibung:
Decylacetat, Sigma-Aldrich®
Artikel-Nr:
(WITG5.522.125)
Lieferant:
WITEG LABORTECHNIK
Hersteller-Artikelnummer::
5.522.125
Lokale Artikelnummer::
WITG5.522.125
Beschreibung:
Borosilikatglas 3.3
VE:
1 * 1 ST
Artikel-Nr:
(BOSSBS-9161R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9161R-A488
Lokale Artikelnummer::
BOSSBS-9161R-A488
Beschreibung:
The tripartite motif (TRIM) family of proteins are characterized by a conserved TRIM domain that includes a coiled-coil region, a B-box type zinc finger, one RING finger and three zinc-binding domains. TRIM17 (tripartite motif-containing 17), also known as RBCC, terf or RNF16, is a 477 amino acid protein that contains one RING-type zinc finger, one SPRY domain and one B box-type zinc finger. Expressed nearly exclusively in testis, TRIM17 belongs to the TRIM family and, based on its functional domains, may play a role in transcriptional regulation events. The gene encoding TRIM17 maps to human chromosome 1, which spans 260 million base pairs, contains over 3,000 genes and comprises nearly 8% of the human genome. Chromosome 1 houses a large number of disease-associated genes, including those that are involved in familial adenomatous polyposis, Stickler syndrome, Parkinson’s disease, Gaucher disease, schizophrenia and Usher syndrome. Aberrations in chromosome 1 are found in a variety of cancers, including head and neck cancer, malignant melanoma and multiple myeloma.
VE:
1 * 100 µl
Lieferant:
ENDRESS HAUSER
Beschreibung:
Digitaler Allround-Redox-Sensor mit geringem Wartungsaufwand und langer Lebensdauer.
Artikel-Nr:
(EHERC11665300)
Lieferant:
EHRENSTORFER
Hersteller-Artikelnummer::
C11665300
Lokale Artikelnummer::
EHERC11665300
Beschreibung:
4-Cholesten-3-on
VE:
1 * 0,1 g
Artikel-Nr:
(SIAL328154-5G)
Lieferant:
Sigma-Aldrich
Hersteller-Artikelnummer::
328154-5G
Lokale Artikelnummer::
SIAL328154-5G
Beschreibung:
2,4,5-Trifluorbenzoesäure, Sigma-Aldrich®
VE:
1 * 5 g
Artikel-Nr:
(BOSSBS-10361R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-10361R-A555
Lokale Artikelnummer::
BOSSBS-10361R-A555
Beschreibung:
Fibrinogen is the main protein of blood coagulation system. It is a large protein and it consists of two identical subunits that contain three polypeptide chains: alpha, beta and gamma. All chains are connected with each other by a number of disulfide bonds. Fibrinopeptides A (1 to 16 amino acids) and B (1 to 17 amino acids) are released by thrombin from the N terminal parts of alpha and beta chains, respectively. In this way fibrinogen is converted into fibrin, which by means of polymerization forms a fibrin clot. Fibrinogen clotting underlies pathogenesis of MI, thromboembolism and thromboses of arteries and veins, since fibrin is the main substrate for thrombus formation. Fibrinogen activation is also involved in pathogenesis of inflammation, tumor growth and many other diseases. The normal fibrinogen concentration in plasma is about 3 mg/ml. The elevated level of fibrinogen in patient's blood is regarded as an independent risk factor for cardiovascular diseases. An increase in blood fibrinogen concentration was shown to be a strong predictor of coronary heart disease (Sonel A. et al, and Rapold H.J. et al). All these facts make fibrinogen an important parameter in the diagnosis of cardiovascular diseases.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11607R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11607R-A488
Lokale Artikelnummer::
BOSSBS-11607R-A488
Beschreibung:
The leucine-rich (LRR) repeat is a 20-30 amino acid motif that forms a hydrophobic å/∫ horseshoe fold, allowing it to accommodate several leucine residues within a tightly packed core. All LRR repeats contain a variable segment and a highly conserved segment, the latter of which accounts for 11 or 12 residues of the entire LRR motif. LRRC54 (leucine-rich repeat-containing protein 54), also known as tsukushin, TSKU or E2-induced gene 4 protein (E2IG4), is a 353 amino acid secreted protein that likely localizes to the cell membrane and extracellular compartments. Involved in extracellular secretion and intracellular transport, LRRC54 can be induced by 17-beta-estradiol. Containing nine LRR repeat and a cleavable signal peptide, the gene encoding LRRC54 maps to human chromosome 11, which houses over 1,400 genes and comprises nearly 4% of the human genome. Jervell and Lange-Nielsen syndrome, Jacobsen syndrome, Niemann-Pick disease, hereditary angioedema and Smith-Lemli-Opitz syndrome are associated with defects in genes that maps to chromosome 11.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-10361R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-10361R-FITC
Lokale Artikelnummer::
BOSSBS-10361R-FITC
Beschreibung:
Fibrinogen is the main protein of blood coagulation system. It is a large protein and it consists of two identical subunits that contain three polypeptide chains: alpha, beta and gamma. All chains are connected with each other by a number of disulfide bonds. Fibrinopeptides A (1 to 16 amino acids) and B (1 to 17 amino acids) are released by thrombin from the N terminal parts of alpha and beta chains, respectively. In this way fibrinogen is converted into fibrin, which by means of polymerization forms a fibrin clot. Fibrinogen clotting underlies pathogenesis of MI, thromboembolism and thromboses of arteries and veins, since fibrin is the main substrate for thrombus formation. Fibrinogen activation is also involved in pathogenesis of inflammation, tumor growth and many other diseases. The normal fibrinogen concentration in plasma is about 3 mg/ml. The elevated level of fibrinogen in patient's blood is regarded as an independent risk factor for cardiovascular diseases. An increase in blood fibrinogen concentration was shown to be a strong predictor of coronary heart disease (Sonel A. et al, and Rapold H.J. et al). All these facts make fibrinogen an important parameter in the diagnosis of cardiovascular diseases.
VE:
1 * 100 µl
Lieferant:
Sigma-Aldrich
Beschreibung:
3-(3,4-Dihydroxyphenyl)-D-alanin, Sigma-Aldrich®
Lieferant:
Sigma-Aldrich
Beschreibung:
Fumarsäure, Sigma-Aldrich®
Artikel-Nr:
(SIAL730742-5G)
Lieferant:
Sigma-Aldrich
Hersteller-Artikelnummer::
730742-5G
Lokale Artikelnummer::
SIAL730742-5G
Beschreibung:
2-Iod-3-nitrotoluol, Sigma-Aldrich®
VE:
1 * 5 g
Artikel-Nr:
(WITG9.350.303)
Lieferant:
WITEG LABORTECHNIK
Hersteller-Artikelnummer::
9.350.303
Lokale Artikelnummer::
WITG9.350.303
Beschreibung:
Sample vials made of borosilicate glass for general use.
VE:
1 * 100 ST
Artikel-Nr:
(GRANC1GR)
Lieferant:
GRANT INSTRUMENTS
Hersteller-Artikelnummer::
C1GR
Lokale Artikelnummer::
GRANC1GR
Beschreibung:
Eintauchkühler werden hauptsächlich als Zubehör zur Gegenkühlung beim Anschluss an ein Wärme-Umwälzthermostat oder zur schnellen Abkühlung von Flüssigkeiten auf niedrige Temperaturen verwendet.
VE:
1 * 1 ST
Lieferant:
Thermo Scientific
Beschreibung:
PS, transparent.
Preis auf Anfrage
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