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Artikel-Nr:
(BOSSBS-1910R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1910R-CY7
Lokale Artikelnummer::
BOSSBS-1910R-CY7
Beschreibung:
Membrane Receptors Transforming growth factor beta is a multifunctional cytokine known to modulate several tissue development and repair processes, including cell differentiation, cell cycle progression, cellular migration, adhesion, and extracellular matrix production. There are 3 forms encoded by separate genes TGFB1, TGFB2, and TGFB3. The diverse effects of TGF beta are mediated by the TGF beta receptors and cell surface binding proteins. In addition to type I TGF beta receptor (TGFBR1) and type II (TFGBR2), type III (TGF beta III receptor) has been identified. It is a glycoprotein that binds TGF beta and exists in both a membrane bound and a soluble form. It may serve as a receptor accessory molecule in both the TGF beta and fibroblast growth factor systems. TGF beta III receptor lacks a recognizable signaling domain and has no clearly defined role in TGF beta signaling. Endothelial cells undergoing epithelial mesenchymal transformation express TGF beta III receptor, and TGF beta III receptor specific antisera inhibits mesenchyme formation and migration. Misexpression of TGF beta III receptor in nontransforming ventricular endothelial cells conferrs transformation in response to TGFB2. These results support a model where TGF beta III receptor localizes transformation in the heart and plays an essential, nonredundant role in TGF beta signaling. TGF beta III receptor, or beta glycan, can function as an inhibin coreceptor with ActRII. TGF beta III receptor binds inhibin with high affinity and enhances binding in cells coexpressing ActRII and TGF beta III receptor. Inhibin forms crosslinked complexes with both recombinant and endogenously expressed TGF beta III receptor and ActRII. TGF beta III receptor confers inhibin sensitivity to cell lines that otherwise respond poorly to this hormone.
VE:
1 * 100 µl
Lieferant:
Thermo Scientific
Beschreibung:
Gadoliniumtrinitrat Hexahydrat 99.9% (bezogen auf die Metalle der seltenen Erden)
Lieferant:
Thermo Scientific
Beschreibung:
Kaliumiodid 99.995% (bezogen auf die Metalle der seltenen Erden), reinst
Artikel-Nr:
(BOSSBS-7689R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-7689R
Lokale Artikelnummer::
BOSSBS-7689R
Beschreibung:
Potassium channels are a group of ubiquitously expressed proteins that serve numerous functions in excitable and non-excitable cells. One class of integral membrane potassium channels is the large conductance, calcium-activated potassium channel (Maxi K+). Maxi K+ differs from most other potassium channels in that its activation is controlled by both increases in intracellular calcium and by membrane depolarization. Maxi K+ dual activation is possible because of its structure. The core of the channel, which is similar to other potassium channels, is a Maxi K+ alpha homotetramer that contains both a voltage sensor and an intracellular calcium binding domain. In vascular smooth muscle, an auxiliary beta-subunit is found in a 1:1 stoichiometry. The beta-subunit exhibits its effect on the Maxi K+ channel by effectively decreasing by 5- to 10- fold the concentration of calcium required to keep the pore open. Maxi K+ beta is the target for possible therapeutics because of its role in blood flow and blood pressure regulation.
VE:
1 * 100 µl
Lieferant:
Alfa Aesar
Beschreibung:
Digalliumtriselenid ≥99,99% (Metall-Basis)
Artikel-Nr:
(87815.290)
Lieferant:
VWR Chemicals
Lokale Artikelnummer::
VWRC87815.290
Beschreibung:
Starting materials:
Solution A. Copper sulfate R/ Water R Solution B. anhydrous Sodium carbonate R / Potassium sodium tartrate R/ Sodium hydrogen carbonate R/ anhydrous Sodium sulfate R/ Water R
VE:
1 * 1 L
Artikel-Nr:
(ABCAAB283318-100)
Lieferant:
Abcam
Hersteller-Artikelnummer::
AB283318-100
Lokale Artikelnummer::
ABCAAB283318-100
Beschreibung:
Anti-Sodium Potassium ATPase Mouse Monoclonal Antibody [clone: EP1845Y]
VE:
1 * 100 µl
 This is a MarketSource item. Additional charges may apply
Lieferant:
APOLLO SCIENTIFIC
Beschreibung:
Europiumtrinitrat Hydrat 99,9%
Lieferant:
Alfa Aesar
Beschreibung:
tri-Kaliumcitrat Monohydrat ≥99%
Artikel-Nr:
(BOSSBS-5403R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5403R-CY5
Lokale Artikelnummer::
BOSSBS-5403R-CY5
Beschreibung:
KCNC1 mediates the voltage-dependent potassium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a potassium-selective channel through which potassium ions may pass in accordance with their electrochemical gradient. It forms a heteromultimer with KCNG3, KCNG4 and KCNV2.
VE:
1 * 100 µl
Lieferant:
APOLLO SCIENTIFIC
Beschreibung:
Europiumtrinitrat Hydrat 99.999%
Artikel-Nr:
(R033)
Lieferant:
G-Biosciences
Hersteller-Artikelnummer::
R033
Lokale Artikelnummer::
GENOR033
Beschreibung:
Molecular biology universal kit, contains 25 ml each of ammonium acetate, calcium chloride, EDTA, lithium acetate, magnesium chloride, potassium acetate, potassium chloride, SDS, sodium chloride, TE, Tris pH 7,0 and Tris pH 8,0
VE:
1 * 1 KIT
Artikel-Nr:
(BOSSBS-5402R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5402R-A488
Lokale Artikelnummer::
BOSSBS-5402R-A488
Beschreibung:
KCNC1 mediates the voltage-dependent potassium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a potassium-selective channel through which potassium ions may pass in accordance with their electrochemical gradient. It forms a heteromultimer with KCNG3, KCNG4 and KCNV2.
VE:
1 * 100 µl
Artikel-Nr:
(USBIT8250-50D)
Lieferant:
US Biological
Hersteller-Artikelnummer::
T8250-50D
Lokale Artikelnummer::
USBIT8250-50D
Beschreibung:
Anti-Transforming Growth Factor beta Receptor III Mouse Monoclonal Antibody [clone: 8H143]
VE:
1 * 500 µG
Artikel-Nr:
(BOSSBS-9931R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9931R-A680
Lokale Artikelnummer::
BOSSBS-9931R-A680
Beschreibung:
Potassium channels are present in most mammalian cells, where they participate in a wide range of physiologic responses. The protein encoded by this gene is an integral membrane protein and inward-rectifier type potassium channel. The encoded protein, which has a greater tendency to allow potassium to flow into a cell rather than out of a cell, is controlled by G-proteins. It may associate with two other G-protein-activated potassium channels to form a heteromultimeric pore-forming complex.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3034R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3034R-A488
Lokale Artikelnummer::
BOSSBS-3034R-A488
Beschreibung:
This is the catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of sodium and potassium ions across the plasma membrane. This action creates the electrochemical gradient of sodium and potassium ions, providing the energy for active transport of various nutrients.
VE:
1 * 100 µl
Preis auf Anfrage
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Dieses Produkt kann nur an eine Lieferadresse versandt werden die über die entsprechende Lizenzen verfügt. Für weitere Hilfe bitte kontaktieren Sie Ihr VWR Vertriebszentrum.
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