3,6-Dichloropyrazine-2-carbonitrile
Artikel-Nr:
(BOSSBS-13343R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13343R-A488
Lokale Artikelnummer::
BOSSBS-13343R-A488
Beschreibung:
The GGA family of proteins (Golgi-localized, ARF-binding proteins) are ubiquitous coat proteins that facilitate the trafficking of soluble proteins from the trans-Golgi network (TGN) to endosomes/lysosomes by means of interactions with TGN-sorting receptors, ARF (ADP-ribosylation factor), and clathrin (1?). Members of the GGA family, GGA1,GGA2 (also known as VEAR) and GGA3, are multidomain proteins that bind mannose 6-phosphate receptors (MPRs) (1,2,4). GGAs have modular structures with an N-terminal VHS (VPS-27, Hrs, and STAM) domain followed by a GAT (GGA and TOM1) domain, a connecting hinge segment, and a C-terminal GAE (?adaptin ear) domain (5). The amino-terminal VHS domains of GGAs form complexes with the cytoplasmic domains of sorting receptors by recognizing acidic-cluster di-leucine (ACLL) sequences (3). GGA1 and GGA2 do not associate with each other, but they do colocalize on perinuclear membranes (2). The cytosolic domain of memapsin 2, but not that of memapsin 1, binds the VHS domains of GGA1 and GGA2 (6). The human GGA1 gene maps to chromosome 22 and encodes a protein that shares 45% sequence identity with GGA2 and GGA3 (1).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-13343R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13343R-A555
Lokale Artikelnummer::
BOSSBS-13343R-A555
Beschreibung:
The GGA family of proteins (Golgi-localized, ARF-binding proteins) are ubiquitous coat proteins that facilitate the trafficking of soluble proteins from the trans-Golgi network (TGN) to endosomes/lysosomes by means of interactions with TGN-sorting receptors, ARF (ADP-ribosylation factor), and clathrin (1?). Members of the GGA family, GGA1,GGA2 (also known as VEAR) and GGA3, are multidomain proteins that bind mannose 6-phosphate receptors (MPRs) (1,2,4). GGAs have modular structures with an N-terminal VHS (VPS-27, Hrs, and STAM) domain followed by a GAT (GGA and TOM1) domain, a connecting hinge segment, and a C-terminal GAE (?adaptin ear) domain (5). The amino-terminal VHS domains of GGAs form complexes with the cytoplasmic domains of sorting receptors by recognizing acidic-cluster di-leucine (ACLL) sequences (3). GGA1 and GGA2 do not associate with each other, but they do colocalize on perinuclear membranes (2). The cytosolic domain of memapsin 2, but not that of memapsin 1, binds the VHS domains of GGA1 and GGA2 (6). The human GGA1 gene maps to chromosome 22 and encodes a protein that shares 45% sequence identity with GGA2 and GGA3 (1).
VE:
1 * 100 µl
Lieferant:
Thermo Fisher Scientific
Beschreibung:
Level 2 septa are manufactured and tested to ensure low bleeding, robustness, and reproducibility of results for your routine GC-MS and LC-MS analyses.
Lieferant:
Borer Chemie
Beschreibung:
Flüssiges, alkalisches Reinigungskonzentrat zur maschinellen Reinigung von Laborglas und wiederverwendbaren Labormaterialien
Artikel-Nr:
(BOSSBS-9748R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9748R
Lokale Artikelnummer::
BOSSBS-9748R
Beschreibung:
Ankyrins are membrane adaptor molecules that play important roles in coupling integral membrane proteins to the spectrin-based cytoskeleton network. Mutations of ankyrin genes lead to severe genetic diseases, such as fatal cardiac arrhythmias and hereditary spherocytosis. ANKRD22 (ankyrin repeat domain 22) is a 191 amino acid protein that contains four ANK repeats. Conserved in chimpanzee, dog, cow, mouse, rat, chicken and zebrafish, ANKRD22 is encoded by a gene that maps to human chromosome 10. Chromosome 10 encodes nearly 1,200 genes within 135 million bases, making up approximately 4.5% of the human genome. Several protein-coding genes, including those that encode for chemokines, cadherins, excision repair proteins, early growth response factors (Egrs) and fibroblast growth receptors (FGFRs), are located on chromosome 10. Defects in genes that map to chromosome 10 are associated with Charcot-Marie Tooth disease, Jackson-Weiss syndrome, Usher syndrome, nonsyndromatic deafness, Wolman’s syndrome, Cowden syndrome, multiple endocrine neoplasia type 2 and porphyria.
VE:
1 * 100 µl
Lieferant:
Sigma-Aldrich
Beschreibung:
4,4'-(Hexafluorisopropyliden)diphthalsäureanhydrid, Sigma-Aldrich®
Lieferant:
MP Biomedicals
Beschreibung:
Synonym: D-threo-2,2-dichloro-N-[β-hydroxy-α-(hydroxymethyl)-p-(methyl- sulfonyl)phenethyl]-acetamide
Artikel-Nr:
(EDQMY0001531)
Lieferant:
EDQM
Hersteller-Artikelnummer::
Y0001531
Lokale Artikelnummer::
EDQMY0001531
Beschreibung:
Organic Standard, Anastrozole impurity E, 2,2'-[5-(hydroxymethyl)benzene-1,3-diyl]bis(2-methylpropanenitrile), Ph. Eur. standard
VE:
1 * 10 mg
Lieferant:
Sigma-Aldrich
Beschreibung:
Triethanolamin (Trolamin, TEA), Sigma-Aldrich®
Lieferant:
Sigma-Aldrich
Beschreibung:
Triethylenglycol, Sigma-Aldrich®
Artikel-Nr:
(PROOMM0641.00)
Lieferant:
LGC Standards PROMOCHEM
Hersteller-Artikelnummer::
MM0641.00
Lokale Artikelnummer::
PROOMM0641.00
Beschreibung:
Gemfibrozil
VE:
1 * 250 mg
Artikel-Nr:
(MOLEM22387835)
Lieferant:
Molekula
Hersteller-Artikelnummer::
M22387835
Lokale Artikelnummer::
MOLEM22387835
Beschreibung:
(±)-1,1′-Bi-2-naphthol
VE:
1 * 25 g
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Artikel-Nr:
(525-2250)
Lieferant:
VITLAB
Hersteller-Artikelnummer::
103897
Lokale Artikelnummer::
VITL103897
Beschreibung:
PFA.
VE:
1 * 1 ST
Lieferant:
NICKEL ELECTRO
Beschreibung:
Giebeldeckel aus Edelstahl, Für: 22 and 28 L baths (NE1/NE1B/NE2D/NE5 and Duobaths)
Artikel-Nr:
(BOSSBS-9748R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9748R-A555
Lokale Artikelnummer::
BOSSBS-9748R-A555
Beschreibung:
Ankyrins are membrane adaptor molecules that play important roles in coupling integral membrane proteins to the spectrin-based cytoskeleton network. Mutations of ankyrin genes lead to severe genetic diseases, such as fatal cardiac arrhythmias and hereditary spherocytosis. ANKRD22 (ankyrin repeat domain 22) is a 191 amino acid protein that contains four ANK repeats. Conserved in chimpanzee, dog, cow, mouse, rat, chicken and zebrafish, ANKRD22 is encoded by a gene that maps to human chromosome 10. Chromosome 10 encodes nearly 1,200 genes within 135 million bases, making up approximately 4.5% of the human genome. Several protein-coding genes, including those that encode for chemokines, cadherins, excision repair proteins, early growth response factors (Egrs) and fibroblast growth receptors (FGFRs), are located on chromosome 10. Defects in genes that map to chromosome 10 are associated with Charcot-Marie Tooth disease, Jackson-Weiss syndrome, Usher syndrome, nonsyndromatic deafness, Wolman’s syndrome, Cowden syndrome, multiple endocrine neoplasia type 2 and porphyria.
VE:
1 * 100 µl
Lieferant:
BIOLEGEND INC
Beschreibung:
Anti-GFAP (Cocktail) Mouse Monoclonal Antibody [clone: SMI 22]
Preis auf Anfrage
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