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1,8-Dihydroxynaphthalin
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1,8-Dihydroxynaphthalin
Lieferant:
VKI WATER QUALITY INSTITUTE
Beschreibung:
Die von VKI erstellten zertifizierten Referenzmaterialien wurden entwickelt, um geeignete homogene und stabile Referenzmaterialien für die Qualitätskontrolle von Umweltanalysen zur Verfügung zu stellen. Die Zertifizierung wird gemäß dem ISO Guide 30, 31, 33, 34, 35, ISO 5725 und ISO/REMCO N 37 durchgeführt. Sämtliche zertifizierte Referenzmaterialien sind auf nationale Standards zurückzuführen oder wurden von einer Gruppe international anerkannter Labors verifiziert. Sie werden mit einem Analysezertifikat versehen, das den zertifizierten Wert und die Unsicherheit bei einem angegebenen Zuverlässigkeitsgrad angibt.
Artikel-Nr:
(APOSOR4657-1G)
Lieferant:
APOLLO SCIENTIFIC
Hersteller-Artikelnummer::
OR4657-1G
Lokale Artikelnummer::
APOSOR4657-1G
Beschreibung:
2,5-Dimethoxybenzolthiol
VE:
1 * 1 g
Artikel-Nr:
(BSENR-118-100)
Lieferant:
Biosensis
Hersteller-Artikelnummer::
R-118-100
Lokale Artikelnummer::
BSENR-118-100
Beschreibung:
Tyrosine hydroxylase (TH) is the rate-limiting enzyme in the synthesis of the catecholamines dopamine, epinephrine and norepinephrine. Therefore the regulation of the TH enzyme represents the central means for controlling the synthesis of these important catecholamines. FUNCTION: Plays an important role in the physiology of adrenergic neurons. CATALYTIC ACTIVITY: L-tyrosine + tetrahydrobiopterin + O2 = 3,4-dihydroxy-L-phenylalanine + 4a-hydroxytetrahydrobiopterin. COFACTOR: Fe(2+) ion. ENZYME REGULATION: Phosphorylation leads to an increase in the catalytic activity. PATHWAY: Catecholamine biosynthesis; first step. SUBUNIT: Homotetramer. PTM: In vitro, phosphorylation of Ser-19 increases the rate of Ser-40 phosphorylation, which results in enzyme opening and activation. SIMILARITY: Belongs to the biopterin-dependent aromatic amino acid hydroxylase family. The presence of different DNA sequences at the TH locus confers susceptibility to various disorders of the brain including manic-depression and schizophrenia. Parkinson's disease is also considered a TH deficiency as low dopamine levels are a consistent neurochemical abnormality.
VE:
1 * 100 µl
Artikel-Nr:
(BLDPBD140767-10G)
Lieferant:
BLD PHARMATECH GMBH
Hersteller-Artikelnummer::
BD140767-10G
Lokale Artikelnummer::
BLDPBD140767-10G
Beschreibung:
(2,4-Dimethoxybenzyl)methylamine 98%
VE:
1 * 10 g
Lieferant:
APOLLO SCIENTIFIC
Beschreibung:
2,6-Dimethoxybenzylalkohol
Artikel-Nr:
(BOSSBS-13202R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13202R-A680
Lokale Artikelnummer::
BOSSBS-13202R-A680
Beschreibung:
Xenopus winged-helix factor, xFAST-1 (forkhead activin signal transducer-1) is a transcription factor that forms a complex with the receptor-regulated Smad protein, Smad2, and directly binds to activin response elements on DNA (1,2). The human homolog FAST-1 and the corresponding mouse homolog, designated FAST-2, share significant sequence homology with xFAST-1, including a conserved N-terminal forkhead domain that consists of 110 amino acid residues and is essential for binding DNA and regulating transcription in embryogenesis, in tumorigenesis and in the maintenance of differentiated cell states (3,4). FAST-1 and FAST-2 also contain a distinct C-terminal Smad interaction domain that is required for the association with various Smad proteins, including Smad2, Smad3 and Smad4 (3,5). Expression of FAST-1 and FAST-2 is predominantly observed during early development, with lower levels detected in adult tissues (6,7). FAST-1 and FAST-2 mediated DNA binding is attenuated by both TFGß and activin, indicating that these FAST proteins mediate TFGß induced signal transduction (3).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-13202R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13202R-FITC
Lokale Artikelnummer::
BOSSBS-13202R-FITC
Beschreibung:
Xenopus winged-helix factor, xFAST-1 (forkhead activin signal transducer-1) is a transcription factor that forms a complex with the receptor-regulated Smad protein, Smad2, and directly binds to activin response elements on DNA (1,2). The human homolog FAST-1 and the corresponding mouse homolog, designated FAST-2, share significant sequence homology with xFAST-1, including a conserved N-terminal forkhead domain that consists of 110 amino acid residues and is essential for binding DNA and regulating transcription in embryogenesis, in tumorigenesis and in the maintenance of differentiated cell states (3,4). FAST-1 and FAST-2 also contain a distinct C-terminal Smad interaction domain that is required for the association with various Smad proteins, including Smad2, Smad3 and Smad4 (3,5). Expression of FAST-1 and FAST-2 is predominantly observed during early development, with lower levels detected in adult tissues (6,7). FAST-1 and FAST-2 mediated DNA binding is attenuated by both TFGß and activin, indicating that these FAST proteins mediate TFGß induced signal transduction (3).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-13202R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13202R-A555
Lokale Artikelnummer::
BOSSBS-13202R-A555
Beschreibung:
Xenopus winged-helix factor, xFAST-1 (forkhead activin signal transducer-1) is a transcription factor that forms a complex with the receptor-regulated Smad protein, Smad2, and directly binds to activin response elements on DNA (1,2). The human homolog FAST-1 and the corresponding mouse homolog, designated FAST-2, share significant sequence homology with xFAST-1, including a conserved N-terminal forkhead domain that consists of 110 amino acid residues and is essential for binding DNA and regulating transcription in embryogenesis, in tumorigenesis and in the maintenance of differentiated cell states (3,4). FAST-1 and FAST-2 also contain a distinct C-terminal Smad interaction domain that is required for the association with various Smad proteins, including Smad2, Smad3 and Smad4 (3,5). Expression of FAST-1 and FAST-2 is predominantly observed during early development, with lower levels detected in adult tissues (6,7). FAST-1 and FAST-2 mediated DNA binding is attenuated by both TFGß and activin, indicating that these FAST proteins mediate TFGß induced signal transduction (3).
VE:
1 * 100 µl
Lieferant:
Thermo Scientific
Beschreibung:
2,5-Dimethoxybenzylalkohol 99%
Lieferant:
Thermo Scientific
Beschreibung:
2,4-Dimethoxybenzylalkohol 99%
Lieferant:
Alfa Aesar
Beschreibung:
(3,5-Dimethoxy-4-hydroxyphenyl)essigsäure ≥97%
Artikel-Nr:
(BLDPBD61625-1G)
Lieferant:
BLD PHARMATECH GMBH
Hersteller-Artikelnummer::
BD61625-1G
Lokale Artikelnummer::
BLDPBD61625-1G
Beschreibung:
3,5-Dimethoxyphenylboronsäurepinakolester 95%
VE:
1 * 1 g
Artikel-Nr:
(BOSSBS-13202R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13202R-CY7
Lokale Artikelnummer::
BOSSBS-13202R-CY7
Beschreibung:
Xenopus winged-helix factor, xFAST-1 (forkhead activin signal transducer-1) is a transcription factor that forms a complex with the receptor-regulated Smad protein, Smad2, and directly binds to activin response elements on DNA (1,2). The human homolog FAST-1 and the corresponding mouse homolog, designated FAST-2, share significant sequence homology with xFAST-1, including a conserved N-terminal forkhead domain that consists of 110 amino acid residues and is essential for binding DNA and regulating transcription in embryogenesis, in tumorigenesis and in the maintenance of differentiated cell states (3,4). FAST-1 and FAST-2 also contain a distinct C-terminal Smad interaction domain that is required for the association with various Smad proteins, including Smad2, Smad3 and Smad4 (3,5). Expression of FAST-1 and FAST-2 is predominantly observed during early development, with lower levels detected in adult tissues (6,7). FAST-1 and FAST-2 mediated DNA binding is attenuated by both TFGß and activin, indicating that these FAST proteins mediate TFGß induced signal transduction (3).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11604R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11604R-CY3
Lokale Artikelnummer::
BOSSBS-11604R-CY3
Beschreibung:
Na+/Cl- dependent neurotransmitter transporters are a superfamily of transmembrane proteins that contain 12 membrane spanning regions (1). Specifically, the highly hydrophobic Na+/Cl- dependent glycine transporters (GlyT) are crucial for the termination of neurotransmission at glycinergic synapses (2,3). Two different GlyT genes encode GlyT2 and GlyT1, which exists as two isoforms produced by alternative splicing of the same gene located on human chromosome 1p31.3 (3,4). The GlyT1 gene may be an early marker of neural development and encodes glia-specific transporter proteins (3). Although GlyT1 and GlyT2 are both expressed in the brain and spinal cord, each shows a unique pattern of expression (3,5,6). GlyT1 is found only in the white matter of the CNS, whereas GlyT2 is found in the gray matter of the CNS as well as in macrophages and mast cells in peripheral tissues (3,5). The anatomic distribution of GlyT2 mRNA suggests that glycine may act as a supraspinal neurotransmitter and may function as a chemical messenger outside the CNS (5).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-13202R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13202R-CY3
Lokale Artikelnummer::
BOSSBS-13202R-CY3
Beschreibung:
Xenopus winged-helix factor, xFAST-1 (forkhead activin signal transducer-1) is a transcription factor that forms a complex with the receptor-regulated Smad protein, Smad2, and directly binds to activin response elements on DNA (1,2). The human homolog FAST-1 and the corresponding mouse homolog, designated FAST-2, share significant sequence homology with xFAST-1, including a conserved N-terminal forkhead domain that consists of 110 amino acid residues and is essential for binding DNA and regulating transcription in embryogenesis, in tumorigenesis and in the maintenance of differentiated cell states (3,4). FAST-1 and FAST-2 also contain a distinct C-terminal Smad interaction domain that is required for the association with various Smad proteins, including Smad2, Smad3 and Smad4 (3,5). Expression of FAST-1 and FAST-2 is predominantly observed during early development, with lower levels detected in adult tissues (6,7). FAST-1 and FAST-2 mediated DNA binding is attenuated by both TFGß and activin, indicating that these FAST proteins mediate TFGß induced signal transduction (3).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-13202R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13202R-HRP
Lokale Artikelnummer::
BOSSBS-13202R-HRP
Beschreibung:
Xenopus winged-helix factor, xFAST-1 (forkhead activin signal transducer-1) is a transcription factor that forms a complex with the receptor-regulated Smad protein, Smad2, and directly binds to activin response elements on DNA (1,2). The human homolog FAST-1 and the corresponding mouse homolog, designated FAST-2, share significant sequence homology with xFAST-1, including a conserved N-terminal forkhead domain that consists of 110 amino acid residues and is essential for binding DNA and regulating transcription in embryogenesis, in tumorigenesis and in the maintenance of differentiated cell states (3,4). FAST-1 and FAST-2 also contain a distinct C-terminal Smad interaction domain that is required for the association with various Smad proteins, including Smad2, Smad3 and Smad4 (3,5). Expression of FAST-1 and FAST-2 is predominantly observed during early development, with lower levels detected in adult tissues (6,7). FAST-1 and FAST-2 mediated DNA binding is attenuated by both TFGß and activin, indicating that these FAST proteins mediate TFGß induced signal transduction (3).
VE:
1 * 100 µl
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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