2,2\'-Dihydroxybiphenyl
Artikel-Nr:
(EHERC15990100)
Lieferant:
EHRENSTORFER
Hersteller-Artikelnummer::
C15990100
Lokale Artikelnummer::
EHERC15990100
Beschreibung:
cis-Permethrin
VE:
1 * 10 mg
Artikel-Nr:
(763-0454)
Lieferant:
SPIRING ENTERPRISES
Hersteller-Artikelnummer::
MDNA-060-22
Lokale Artikelnummer::
SPIRMDNA-060-22
Beschreibung:
Mini molecular models of DNA with nucleic acids, five-sided sugar molecules and pyramid-shaped phosphate molecules.
VE:
1 * 1 ST
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Artikel-Nr:
(216-3168)
Lieferant:
VITLAB
Hersteller-Artikelnummer::
68894
Lokale Artikelnummer::
VITL68894
Beschreibung:
PP, transparent with clear PE-LD snap on cap.
VE:
1 * 25 ST
Artikel-Nr:
(22912.237)
Lieferant:
VWR Chemicals
Lokale Artikelnummer::
VWRC22912.237
Beschreibung:
Cobalt(II)nitrat Hexahydrat ≥98%, GPR RECTAPUR®
VE:
1 * 250 g
Lieferant:
Corning
Beschreibung:
Reines PS, steril.
Lieferant:
HARVARD APPARATUS
Beschreibung:
The PHD 22/2000 syringe pump series gives you the lowest flow rates, the highest accuracy, the smoothest flow, advanced programmability from the keypad. Ideal for applications in drug/nutritional delivery, electrospinning, microfluidics/nanofluidics and mass spec calibration.
Lieferant:
Thermo Scientific
Beschreibung:
ADA 99% für die Biochemie
Artikel-Nr:
(432-5000)
Lieferant:
DWK Life Sciences
Hersteller-Artikelnummer::
357426
Lokale Artikelnummer::
WHEA357426
Beschreibung:
Borosilikatglas. Gewebehomogenisator mit auswechselbaren Pistillen. Besonders geeignet für Gewebe und zähe Organmaterialien.
VE:
1 * 2 ST
Artikel-Nr:
(BOSSBS-12495R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12495R-CY7
Lokale Artikelnummer::
BOSSBS-12495R-CY7
Beschreibung:
APOBEC proteins inhibit retroviruses by deaminating cytosine residues of viral RNA and DNA. The seven APOBEC3 genes or pseudogenes are found in a cluster thought to result from gene duplication on chromosome 22. Like APOBEC3G, APOBEC3F deaminates deoxycytosine to deoxyuracil in the minus strand of HIV-1 DNA, resulting in G to A hypermutation in the plus strand of DNA. Thus, APOBEC3G and APOBEC3F provide a mechanism for innate immunity to retroviruses, and are also likely contribute to sequence variation observed in many viruses. Viral infectivity factor (Vif) imparts APOBEC3G and APOBEC3F resistance to HIV through impaired translation of their mRNA and accelerated posttranslational degradation of the APOBEC3 proteins by the 26S proteasome. Interestingly, HIV-1 Vif cannot form a complex with APOBEC3G or APOBEC3F of mouse origin as it does with the human protein, and thus mouse APOBEC3G and APOBEC3F function as a potent inhibitors of wildtype HIV-1 replication, where human APOBEC3G and APOBEC3F are only able to inhibit Vif-deficient HIV-1 replication. This implies that induction of APOBEC3G and APOBEC3F activity or a method of blocking their interaction with Vif may provide a method for therapeutic intervention.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-8594R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-8594R-A555
Lokale Artikelnummer::
BOSSBS-8594R-A555
Beschreibung:
Ankyrins are membrane adaptor molecules that play important roles in coupling integral membrane proteins to the spectrin-based cytoskeleton network. Mutations of ankyrin genes lead to severe genetic diseases, such as fatal cardiac arrhythmias and hereditary spherocytosis. ANKRD22 (ankyrin repeat domain 22) is a 191 amino acid protein that contains four ANK repeats. Conserved in chimpanzee, dog, cow, mouse, rat, chicken and zebrafish, ANKRD22 is encoded by a gene that maps to human chromosome 10. Chromosome 10 encodes nearly 1,200 genes within 135 million bases, making up approximately 4.5% of the human genome. Several protein-coding genes, including those that encode for chemokines, cadherins, excision repair proteins, early growth response factors (Egrs) and fibroblast growth receptors (FGFRs), are located on chromosome 10. Defects in genes that map to chromosome 10 are associated with Charcot-Marie Tooth disease, Jackson-Weiss syndrome, Usher syndrome, nonsyndromatic deafness, Wolman’s syndrome, Cowden syndrome, multiple endocrine neoplasia type 2 and porphyria.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-12495R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12495R-CY3
Lokale Artikelnummer::
BOSSBS-12495R-CY3
Beschreibung:
APOBEC proteins inhibit retroviruses by deaminating cytosine residues of viral RNA and DNA. The seven APOBEC3 genes or pseudogenes are found in a cluster thought to result from gene duplication on chromosome 22. Like APOBEC3G, APOBEC3F deaminates deoxycytosine to deoxyuracil in the minus strand of HIV-1 DNA, resulting in G to A hypermutation in the plus strand of DNA. Thus, APOBEC3G and APOBEC3F provide a mechanism for innate immunity to retroviruses, and are also likely contribute to sequence variation observed in many viruses. Viral infectivity factor (Vif) imparts APOBEC3G and APOBEC3F resistance to HIV through impaired translation of their mRNA and accelerated posttranslational degradation of the APOBEC3 proteins by the 26S proteasome. Interestingly, HIV-1 Vif cannot form a complex with APOBEC3G or APOBEC3F of mouse origin as it does with the human protein, and thus mouse APOBEC3G and APOBEC3F function as a potent inhibitors of wildtype HIV-1 replication, where human APOBEC3G and APOBEC3F are only able to inhibit Vif-deficient HIV-1 replication. This implies that induction of APOBEC3G and APOBEC3F activity or a method of blocking their interaction with Vif may provide a method for therapeutic intervention.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-12495R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12495R-CY5
Lokale Artikelnummer::
BOSSBS-12495R-CY5
Beschreibung:
APOBEC proteins inhibit retroviruses by deaminating cytosine residues of viral RNA and DNA. The seven APOBEC3 genes or pseudogenes are found in a cluster thought to result from gene duplication on chromosome 22. Like APOBEC3G, APOBEC3F deaminates deoxycytosine to deoxyuracil in the minus strand of HIV-1 DNA, resulting in G to A hypermutation in the plus strand of DNA. Thus, APOBEC3G and APOBEC3F provide a mechanism for innate immunity to retroviruses, and are also likely contribute to sequence variation observed in many viruses. Viral infectivity factor (Vif) imparts APOBEC3G and APOBEC3F resistance to HIV through impaired translation of their mRNA and accelerated posttranslational degradation of the APOBEC3 proteins by the 26S proteasome. Interestingly, HIV-1 Vif cannot form a complex with APOBEC3G or APOBEC3F of mouse origin as it does with the human protein, and thus mouse APOBEC3G and APOBEC3F function as a potent inhibitors of wildtype HIV-1 replication, where human APOBEC3G and APOBEC3F are only able to inhibit Vif-deficient HIV-1 replication. This implies that induction of APOBEC3G and APOBEC3F activity or a method of blocking their interaction with Vif may provide a method for therapeutic intervention.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-13343R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13343R-A680
Lokale Artikelnummer::
BOSSBS-13343R-A680
Beschreibung:
The GGA family of proteins (Golgi-localized, ARF-binding proteins) are ubiquitous coat proteins that facilitate the trafficking of soluble proteins from the trans-Golgi network (TGN) to endosomes/lysosomes by means of interactions with TGN-sorting receptors, ARF (ADP-ribosylation factor), and clathrin (1?). Members of the GGA family, GGA1,GGA2 (also known as VEAR) and GGA3, are multidomain proteins that bind mannose 6-phosphate receptors (MPRs) (1,2,4). GGAs have modular structures with an N-terminal VHS (VPS-27, Hrs, and STAM) domain followed by a GAT (GGA and TOM1) domain, a connecting hinge segment, and a C-terminal GAE (?adaptin ear) domain (5). The amino-terminal VHS domains of GGAs form complexes with the cytoplasmic domains of sorting receptors by recognizing acidic-cluster di-leucine (ACLL) sequences (3). GGA1 and GGA2 do not associate with each other, but they do colocalize on perinuclear membranes (2). The cytosolic domain of memapsin 2, but not that of memapsin 1, binds the VHS domains of GGA1 and GGA2 (6). The human GGA1 gene maps to chromosome 22 and encodes a protein that shares 45% sequence identity with GGA2 and GGA3 (1).
VE:
1 * 100 µl
Lieferant:
Sigma-Aldrich
Beschreibung:
Triisopropylorthoformiat, Sigma-Aldrich®
Artikel-Nr:
(KRAF05326.0801)
Lieferant:
Bernd Kraft
Hersteller-Artikelnummer::
05326.0801
Lokale Artikelnummer::
KRAF05326.0801
Beschreibung:
Silber
VE:
1 * 10 g
Lieferant:
Sigma-Aldrich
Beschreibung:
Silber, Sigma-Aldrich®
Preis auf Anfrage
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