2,2-Difluoroethyl+3-fluoropropyl+carbonate
Artikel-Nr:
(SIAL244104-500G)
Lieferant:
Sigma-Aldrich
Hersteller-Artikelnummer::
244104-500G
Lokale Artikelnummer::
SIAL244104-500G
Beschreibung:
Woodsche Legierung (Lipowitz Legierung), Stangen, Sigma-Aldrich®
VE:
1 * 500 g
Lieferant:
HUBER
Beschreibung:
Einhängethermostate bilden die Grundlage für viele verschiedene Kombinationen mit Polycarbonat- oder Edelstahl-Badgefäßen. Alle Modelle sind mit einer leistungsstarken Druck-/Saugpumpe ausgestattet und erfüllen die Anforderungen der Sicherheitsklasse III (FL) für die Verwendung mit brennbaren Flüssigkeiten. Zusammen mit einem Kältebad können Temperaturen von bis zu −30 °C erreicht werden. Eine Schraubzwinge ist im Lieferumfang enthalten, sodass die Thermostate leicht an allen beliebigen Gefäßen angebracht werden können. Ein Pumpenadapter für die externe Temperaturregelung sowie Kühlschlangen für einen Kühlwasseranschluss sind als optionales Zubehör erhältlich.
Artikel-Nr:
(PRSI33-205)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
33-205
Lokale Artikelnummer::
PRSI33-205
Beschreibung:
This antibody recognises a cell surface glycoprotein of 95/115/135 kDa (depending upon the extent of glycosylation), identified as CD43 [Workshop IV]. 70-90% of T-cell lymphomas and 22-37% of B-cell lymphomas express CD43. No reactivity has been observed with reactive B-cells. So a B-lineage population that co-expresses CD43 is highly likely to be a malignant lymphoma, especially a low-grade lymphoma, rather than a reactive B-cell population. When CD43 antibody is used in combination with CD20 antibody, effective immunophenotyping of the lymphomas in formalin-fixed tissues can be obtained. Co-staining of a lymphoid infiltrate with CD20 and CD42 antibody argues against a reactive process and favors a diagnosis of lymphoma.
VE:
1 * 100 µG
New Product
Lieferant:
Sigma-Aldrich
Beschreibung:
DSM MonoPhos Family of Highly Efficient Privileged Ligands
Artikel-Nr:
(PRSI90-331)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
90-331
Lokale Artikelnummer::
PRSI90-331
Beschreibung:
FGF-2 (Basic fibroblast growth factor) belongs to the FGF superfamily that is made up of 22 different fibroblast growth factor genes. FGF-2 and FGF-1 (acidic FGF) are unique in that they do not follow the conventional signal sequence for secretion. FGF-2 is found in five isoforms via alternative initiation of translation. Signalling of FGF-2 occurs through the high-affinity tyrosine kinase receptors FGFR1-4. FGF-2 is a potent wide-spectrum mitogen whose overexpression is associated with immortalisation and unregulated cell proliferation in many tumors. FGF-2 functions in angiogenesis, cell survival, tissue repair, embryonic development and inflammation. FGF-2 is widely used to maintain the self-renewal of human embryonic stem cells (ESCs) and to induce pluripotent stem cells. FGF-2 is an established neurogenic factor for proliferation and differentiation of multipotent neural stem cells both during development and in the adult mouse brain as well.
VE:
1 * 10 µG
Artikel-Nr:
(PRSI7175)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
7175
Lokale Artikelnummer::
PRSI7175
Beschreibung:
Alpha-tubulin Antibody: Alpha-tubulin belongs to the tubulin superfamily, which is composed of six distinct families. Along with beta-tubulins, alpha-tubulins are the major components of microtubules. These microtubules are involved in a wide variety of cellular activities ranging from mitosis and transport events to cell movement and the maintenance of cell shape. Alpha- and beta-tubulin dimers are assembled to 13 protofilaments that form a microtubule of 22-nm diameter. Tyrosine ligase adds a C-terminal tyrosine to monomeric alpha-tubulin. Assembled microtubules can again be detyrosinated by a cytoskeleton-associated carboxypeptidase. Another post-translational modification of detyrosinated alpha-tubulin is C-terminal polyglutamylation, which is characteristic of microtubules in neuronal cells and the mitotic spindle. Like GAPDH and beta-Actin, this antibody makes an excellent loading control in immunoblots.
VE:
1 * 100 µG
Lieferant:
MP Biomedicals
Beschreibung:
Ricinoleic Acid is a naturally occurring 12-hydroxy fatty acid constituting about 90% of the fatty acids in castor oil. Has the capacity to serve as a substrate for the synthesis of the conjugated linoleic acids.
Artikel-Nr:
(PRSI91-074)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
91-074
Lokale Artikelnummer::
PRSI91-074
Beschreibung:
Human Chemokine (C-C Motif) Ligand 23 (CCL23) is a small cytokine belonging to the CC chemokine family. CCL23 is also known as myeloid progenitor inhibitory factor MPIF-1, CK8 and SCYA23. CCL23 cDNA encodes a 120 amino acid residue precursor protein with a putative 21 amino acid residue signal peptide that is cleaved to generate a 99 amino acid residue mature CCL23 (amino acids 22 -120). Additional N-terminal Processing of the 99 amino acid residue variant can generate a 75 amino acid residue peptide (amino acid 46-120) that is significantly more active than the 99 amino acid residue variant. CCL23 binds to CCR1 with high affinity and has chemotactic activity for monocytes, dendritic cells, and osteoclast precursors. CCL23 enhances angiogenesis of endothelial cells, but reduces the proliferation of progenitor cells giving rise to granulocyte and monocyte lineages.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI91-307)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
91-307
Lokale Artikelnummer::
PRSI91-307
Beschreibung:
Cytotoxic and Regulatory T-Cell Molecule (CRTAM) is a member of Nectin family under the immunoglobulin superfamily that is expressed by activated CD8+ and NK T cells. CRTAM is found in spleen, thymus, small intestine, peripheral blood, and it is highly expressed by Purkinje cells of the cerebellum. CRTAM is a type I transmembrane glycoprotein containing one Ig-like C2-type domain and one Ig-like V-type domain in its extracellular domain, while its cytoplasmic region shows a potential class I PDZ domain. CRTAM is expressed as a homodimer on the cell surface but does not show homotypic binding in trans. The high affinity of CRTAM/IGSF4 adhesion allows CRTAM to disrupt IGSF4 homotypic interactions. IGSF4 and T cell receptor coengagement of CD8+ cells expressiong CRTAM induces increased IFN gamma or IL-22 production.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI34-166)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
34-166
Lokale Artikelnummer::
PRSI34-166
Beschreibung:
It recognises a cell surface glycoprotein of 95/115/135 kDa (depending upon the extent of glycosylation), identified as CD43. 70-90% of T-cell lymphomas and from 22-37% of B-cell lymphomas express CD43. No reactivity has been observed with reactive B-cells. So a B-lineage population that co-expresses CD43 is highly likely to be a malignant lymphoma, especially a low-grade lymphoma, rather than a reactive B-cell population. When CD43 antibody is used in combination with anti-CD20, effective immunophenotyping of the lymphomas in formalin-fixed tissues can be obtained. Co-staining of a lymphoid infiltrate with anti-CD20 and anti-CD43 argues against a reactive process and favors a diagnosis of lymphoma.
VE:
1 * 100 µG
New Product
Artikel-Nr:
(SPCME1040-500GM)
Lieferant:
Spectrum Chemical
Hersteller-Artikelnummer::
E1040-500GM
Lokale Artikelnummer::
SPCME1040-500GM
Beschreibung:
(Ethylenedinitrilo)tetraacetic Acid, Powder, Reagent, ACS, is generally abbreviated as EDTA, a colorless, water soluble aminopolycarboxylic acid and solid. It is used by many industries and in the laboratory for applications ranging from a sequestering agent to chelation therapy. As an ACS grade Reagent, this Spectrum Chemical manufactured compound is used as the quality standard against which other substances are graded and has met the toughest regulatory standards for quality and pureness.
VE:
1 * 500 g
Artikel-Nr:
(PRSI5111)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
5111
Lokale Artikelnummer::
PRSI5111
Beschreibung:
ZBED1 Antibody: ZBED1, also known as DREF, is the human homolog of the Drosophila protein DREF, a transcriptional regulatory factor required for expression of genes involved in DNA replication and cell proliferation. RNA interference (RNAi) experiments targeting ZBED1 RNA resulted in the inhibition of S phase entry and reduction of histone H1 mRNA in HeLa cells, suggesting that ZBED1 also plays a role in cell proliferation in human cells. At least 22 ribosomal proteins (RPs) possess ZBED1 binding sites in their promoters; anti-ZBED1 RNAi also resulted in decreased RP gene expression. Immunoprecipitation analyses have shown that ZBED1 self-associates in vivo via a carboxyl-terminal hATC domain, and this self-association is required for nuclear localization and DNA binding.
VE:
1 * 100 µG
Artikel-Nr:
(PIER21335)
Lieferant:
Thermo Scientific
Hersteller-Artikelnummer::
21335
Lokale Artikelnummer::
PIER21335
Beschreibung:
Thermo Scientific EZ-Link Sulfo-NHS-LC-Biotin is an intermediate-length, water-soluble biotinylation reagent for labeling antibodies, proteins and other molecules that have primary amines.
VE:
1 * 100 mg
Artikel-Nr:
(BOET07.051.2000)
Lieferant:
BOETTGER PAUL
Hersteller-Artikelnummer::
07.051.2000
Lokale Artikelnummer::
BOET07.051.2000
Beschreibung:
Crystal clear flat bottom tube with fitted push-in-plug.
VE:
1 * 1.000 ST
Artikel-Nr:
(466-3249)
Lieferant:
Binder
Hersteller-Artikelnummer::
9010-0194
Lokale Artikelnummer::
BIND9010-0194
Beschreibung:
Universal-Trockenschränke mit Edelstahlkammer, die sich bestens für einen Einsatz in der Pharmaindustrie, chemischen Industrie, Biotechnologie, Medizin und an Universitäten eignen. Die Trockenschränke verfügen über ein Temperaturrampenprogramm, einen einstellbaren TWB-Temperaturwählbegrenzer der Klasse 2 mit optischem Alarm sowie einen einstellbaren Luftwechsel durch den Luftklappensteller und das Abluftrohr (Ø 50 mm). Sie bieten schnelle Erholzeiten nach dem Öffnen der Türe bzw. einem Luftwechsel.
VE:
1 * 1 ST
Artikel-Nr:
(STMC100-1394)
Lieferant:
Stemcell Technologies
Hersteller-Artikelnummer::
100-1394
Lokale Artikelnummer::
STMC100-1394
Beschreibung:
Stimulating T cells with HPV16 (E7) Peptide pool releases downstream cytokines and upregulates activation markers, enabling antigen-specific T cells to be detected or isolated for analysis. HPV16 (E7) Peptide pool is a lyophilised mixture of 22 peptides from protein E7 of human papillomavirus type 16 (HPV16) consisting of 15-mer peptides with 11-amino-acid overlaps that cover amino acids 1 to 98 on protein E7. E7 is an oncoprotein that binds and mediates degradation of the retinoblastoma tumor suppressor protein pRB (Gonzalez <i>et al.</i>). E7 together with E6 demonstrated the ability to immortalize human keratinocytes in vitro, which likely has significance for HPVs oncogenic potential (Hawley-Nelson <i>et al.</i>). Viral peptide pools are useful for a broad range of applications, including vaccine development, immunological research, and diagnostic assay development.
VE:
1 * 1 LE
New Product
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