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(Phenylthio)acetonitril
Lieferant:
ELTEN
Beschreibung:
The Infinergy® sole core cushions impacts and provides a rebound effect when the compressive impulse subsides, for more energy in every step.
Artikel-Nr:
(BOSSBS-9120R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9120R-CY7
Lokale Artikelnummer::
BOSSBS-9120R-CY7
Beschreibung:
Component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes. The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of SCF-type E3 ligase complexes, leading to decrease the Ubl ligase activity of SCF-type complexes such as SCF, CSA or DDB2. The complex is also involved in phosphorylation of p53/TP53, c-jun/JUN, IkappaBalpha/NFKBIA, ITPK1 and IRF8, possibly via its association with CK2 and PKD kinases. CSN-dependent phosphorylation of TP53 and JUN promotes and protects degradation by the Ubl system, respectively. Has some glucocorticoid receptor-responsive activity.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11019R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11019R
Lokale Artikelnummer::
BOSSBS-11019R
Beschreibung:
May participate in the regulation of T-cell-mediated immune response. May play a protective role in tumor cells by inhibiting natural-killer mediated cell lysis as well as a role of marker for detection of neuroblastoma cells. May be involved in the development of acute and chronic transplant rejection and in the regulation of lymphocytic activity at mucosal surfaces. Could also play a key role in providing the placenta and fetus with a suitable immunological environment throughout pregnancy. Both isoform 1 and isoform 2 appear to be redundant in their ability to modulate CD4 T-cell responses. Isoform 2 is shown to enhance the induction of cytotoxic T-cells and selectively stimulates interferon gamma production in the presence of T-cell receptor signaling.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-13493R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13493R-CY5
Lokale Artikelnummer::
BOSSBS-13493R-CY5
Beschreibung:
Involved in transport from the ER to the Golgi apparatus as well as in intra-Golgi transport. It belongs to a super-family of proteins called t-SNAREs or soluble NSF (N-ethylmaleimide-sensitive factor) attachment protein receptor. May play a protective role against hydrogen peroxide induced cytotoxicity under glutathione depleted conditions in neuronal cells by regulating the intracellular ROS levels via inhibition of p38 MAPK (MAPK11, MAPK12, MAPK13 and MAPK14). Participates in docking and fusion stage of ER to cis-Golgi transport. Plays an important physiological role in VLDL-transport vesicle-Golgi fusion and thus in VLDL delivery to the hepatic cis-Golgi.
VE:
1 * 100 µl
Lieferant:
ELTEN
Beschreibung:
ESD safety ankle boot made from hydrophobised suede/microfibre upper and a PU/PU sole (Crossworker).
Lieferant:
ELTEN
Beschreibung:
ESD safety ankle boots made from hydrophobised microfibre/hydrophobised textile material and a TPU/PU sole (Wellmaxx Trainers Power).
Lieferant:
VWR Collection
Beschreibung:
Diese Einwegkittel mit Rückenverschluss sind aus nicht gewebtem, atmungsaktivem SMS-Gewebe gefertigt. Ideal für den Einsatz im Gesundheitswesen und in Krankenhäusern.
Lieferant:
VWR Collection
Beschreibung:
VWR® Advanced SF Kittel aus einem Polypropylen-Spinnvlies (SPP) mit atmungsaktiver Polyethylen-Film-Beschichtung.
Lieferant:
3M
Beschreibung:
Diese Maskenfilter sind leicht, bequem und bieten einen verlässlichen Schutz vor Partikeln. Bei Verwendung mit Masken der 3M™ Serie 6000 ist ein 3M™ 502 Adapter erforderlich.
Lieferant:
ANSELL HEALTH CARE
Beschreibung:
Diese Unterhandschuhe aus Baumwolle mit weicher PVC-Beschichtung behalten ihre Fingerfertigkeit und Geschmeidigkeit bei niedrigen Temperaturen. Sie bieten chemischen, mechanischen und flüssigen Schutz.
Artikel-Nr:
(BOSSBS-15583R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-15583R-CY3
Lokale Artikelnummer::
BOSSBS-15583R-CY3
Beschreibung:
This gene encodes a type I transmembrane protein and is a tumor-specific endothelial marker that has been implicated in colorectal cancer. The encoded protein has been shown to also be a docking protein or receptor for Bacillus anthracis toxin, the causative agent of the disease, anthrax. The binding of the protective antigen (PA) component, of the tripartite anthrax toxin, to this receptor protein mediates delivery of toxin components to the cytosol of cells. Once inside the cell, the other two components of anthrax toxin, edema factor (EF) and lethal factor (LF) disrupt normal cellular processes. Three alternatively spliced variants that encode different protein isoforms have been described.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-2650R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-2650R-HRP
Lokale Artikelnummer::
BOSSBS-2650R-HRP
Beschreibung:
Calcium-dependent lectin displaying mannose-binding specificity. Induces the formation of Birbeck granules (BGs); is a potent regulator of membrane superimposition and zippering. Binds to sulfated as well as mannosylated glycans, keratan sulfate (KS) and beta-glucans. Facilitates uptake of antigens and is involved in the routing and/or processing of antigen for presentation to T cells. Major receptor on primary Langerhans cells for Candida species, Saccharomyces species, and Malassezia furfur. Protects against human immunodeficiency virus-1 (HIV-1) infection. Binds to high-mannose structures present on the envelope glycoprotein which is followed by subsequent targeting of the virus to the Birbeck granules leading to its rapid degradation.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5918R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5918R
Lokale Artikelnummer::
BOSSBS-5918R
Beschreibung:
Angiopoietin-like protein 3 (Angptl3) functions as a potent lipoprotein lipase inhibitor and is an important component of plasma triglyceride homeostasis. Angptl3 also plays a role in adipose formation and angiogenesis through its interaction with integrin ?v)beta(3). It is secreted by the liver and is functionally defined by the C-terminal fibrinogen (FBN)-like domain and an N-terminal coiled-coil domain. Angptl3 regulates circulating triglyceride levels during different nutritional states thereby mediating the feeding/fasting cycle. A deficiency of Angptl3 results in abnormally low lipid levels, and a repression of the protein may be protective against atherosclerosis. Angptl3 may also play an important role in hyperlipidemia in diabetes.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-15390R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-15390R-A488
Lokale Artikelnummer::
BOSSBS-15390R-A488
Beschreibung:
G-protein coupled receptor. Has been shown to bind the neuroprotective and glioprotective factor prosaposin (PSAP), leading to endocytosis followed by an ERK phosphorylation cascade. However, other studies have shown that prosaposin does not increase activity. It has been suggested that GPR37L1 is a constitutively active receptor which signals through the guanine nucleotide-binding protein G(s) subunit alpha. Participates in the regulation of postnatal cerebellar development by modulating the Shh pathway. Regulates baseline blood pressure in females and protects against cardiovascular stress in males. Mediates inhibition of astrocyte glutamate transporters and reduction in neuronal N-methyl-D-aspartate receptor activity.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-15390R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-15390R-A680
Lokale Artikelnummer::
BOSSBS-15390R-A680
Beschreibung:
G-protein coupled receptor. Has been shown to bind the neuroprotective and glioprotective factor prosaposin (PSAP), leading to endocytosis followed by an ERK phosphorylation cascade. However, other studies have shown that prosaposin does not increase activity. It has been suggested that GPR37L1 is a constitutively active receptor which signals through the guanine nucleotide-binding protein G(s) subunit alpha. Participates in the regulation of postnatal cerebellar development by modulating the Shh pathway. Regulates baseline blood pressure in females and protects against cardiovascular stress in males. Mediates inhibition of astrocyte glutamate transporters and reduction in neuronal N-methyl-D-aspartate receptor activity.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-12565R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12565R-A555
Lokale Artikelnummer::
BOSSBS-12565R-A555
Beschreibung:
ALKB protects DNA and RNA against damage from methylating compounds from the environment by directly reversing 1-methyladenine (1-meA) and 3-methylcytosine (3-meC) cytotoxic alkylation lesions in DNA and RNA. The enzymes act by oxidative demethylation, utilizing ferrous iron and alpha-ketoglutarate as cofactors, 2-oxoglutarate as a co-substrate, and molecular oxygen as the oxidizing agent. Deficiencies in DNA and RNA repair in mammals are associated with cancer, neurological disease and developmental defects. ALKB plays a role in resistance to anti-cancer drugs which attempt to damage tumor DNA. Escherichia coli ALKB protein belongs to the superfamily of 2-oxoglutarate- and iron(II)-dependent oxygenases.
VE:
1 * 100 µl
Preis auf Anfrage
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Dieses Produkt kann nur an eine Lieferadresse versandt werden die über die entsprechende Lizenzen verfügt. Für weitere Hilfe bitte kontaktieren Sie Ihr VWR Vertriebszentrum.
-Additional Documentation May be needed to purchase this item. A VWR representative will contact you if needed.
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