3-Brom-4-methoxybenzoylchlorid
Artikel-Nr:
(PRSI6775)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
6775
Lokale Artikelnummer::
PRSI6775
Beschreibung:
YPEL3 Antibody: YPEL3 (yippee-like 3) belongs to a family of five yippee-like proteins, all of which localize to the centrosome or mitotic spindle and are widely expressed in both adult and fetal tissue. This localization plus the fact that the family of human YPEL proteins share a high degree of sequence homology across species suggests that these proteins may have a conserved function involved in cell division. YPEL3 is a p53-regulated gene whose expression is induced by DNA damage and in turn induces cellular senescence. It appears to function as a tumor suppressor as it is downregulated in colon and breast tumors.
VE:
1 * 100 µG
Artikel-Nr:
(PRSI76-371)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
76-371
Lokale Artikelnummer::
PRSI76-371
Beschreibung:
The RM4-5 monoclonal antibody specifically reacts with mouse CD4, also known as L3T4, a 55 kDa differentiation antigen expressed by the majority of thymocytes, subpopulations of mature T cells (like major histocompatibility complex class II-restricted T lymphocytes), a subset of natural killer T cells, and on pluripotent hematopoietic stem cells. CD4 binds to the major histocompatibility complex class II (MHC class II) and enhances T lymphocyte development and mature T cells functions. In T lymphocytes, CD4 binds to the cytoplasmic tail of enzyme tyrosine kinase (p56lck).Binding of RM4-5 is blocked by the anti-mouse CD4 clone GK1.5.BG Violet 450 conjugate is an alternative to the Pacific Blue, eFluor 450, or BD Horizon V450 dyes. It is excited by the violet (405 nm) laser, with a peak emission of 450 nm.
VE:
1 * 0,025 mg
Artikel-Nr:
(PRSI7421)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
7421
Lokale Artikelnummer::
PRSI7421
Beschreibung:
Bim EL Antibody: Members in the Bcl-2 family are critical regulators of apoptosis by either inhibiting or promoting cell death. Bcl-2 homology 3 (BH3) domain is a potent death domain. BH3 domain containing pro-apoptotic proteins, including Bad, Bax, Bid, Bik, and Hrk, form a growing subclass of the Bcl-2 family. Bim, also known as Bcl-2-like protein 11, is a pro-apoptotic member of this family and interacts with diverse members in the pro-survival Bcl-2 sub-family including Bcl-2, Bcl-xL and Bcl-w. Multiple isoforms of Bim are known to exist, with Bim EL being the longest isoform (1,2).
VE:
1 * 100 µG
Artikel-Nr:
(PRSI46-794)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
46-794
Lokale Artikelnummer::
PRSI46-794
Beschreibung:
Anti-ABCC1 Goat Polyclonal Antibody
VE:
1 * 100 µG
Artikel-Nr:
(PRSI76-415)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
76-415
Lokale Artikelnummer::
PRSI76-415
Beschreibung:
The IM7 monoclonal antibody specifically reacts with all the isoforms and both alloantigens of the CD44 glycoprotein (Pgp-1, Ly-24). CD44 is expressed on hematopoietic and non-hematopoietic cells, bone marrow myeloid cells, memory T lymphocytes, periphery activated B cells, CD4+ T lymphocytes, and CD8+ T lymphocytes. The periphery B and T lymphocytes upregulate the expression of CD44. CD44 binds to hyaluronan molecules, acting as an adhesion molecule.The IM7 antibody inhibits collagen-induced arthritis in DBA/1 mice, prevents central nervous system inflammation associated with experimental autoimmune encephalomyelitis, but exacerbates the experimental autoimmune thyroiditis in CBA/J mice. The IM7 antibody also cross-reacts with dog, human, pig, horse, cat, and cow leukocytes.
VE:
1 * 0,025 mg
Artikel-Nr:
(PRSI92-701)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
92-701
Lokale Artikelnummer::
PRSI92-701
Beschreibung:
Platelet-derived growth factor receptors (PDGFR) are cell surface tyrosine kinase receptors for members of the platelet-derived growth factor (PDGF) family. The PDGF family consists of PDGF-A, -B, -C and -D, which form either homo- or heterodimers (PDGF-AA, -AB, -BB, -CC, -DD). The four PDGFs are inactive in their monomeric forms. PDGFs bind to the protein tyrosine kinase receptors PDGF receptor- alpha and - beta . These two receptor isoforms dimerise upon binding the PDGF dimer, leading to three possible receptor combinations, namely - alpha alpha, - beta beta and - alpha beta . PDGFR alpha and PDGFR beta are members of the class III RTK family. Inappropriate PDGFR alpha and PDGFR beta signalling has been linked to a number of proliferative disorders.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI54-328)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
54-328
Lokale Artikelnummer::
PRSI54-328
Beschreibung:
Anti-GNB3 Rabbit Monoclonal Antibody [clone: D7]
VE:
1 * 100 µG
Artikel-Nr:
(PRSI61-975)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
61-975
Lokale Artikelnummer::
PRSI61-975
Beschreibung:
For WB starting dilution is: 1:1000. For FACS starting dilution is: 1:10~50.
VE:
1 * 400 µl
Artikel-Nr:
(PRSI46-488)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
46-488
Lokale Artikelnummer::
PRSI46-488
Beschreibung:
Anti-THRB Goat Polyclonal Antibody
VE:
1 * 100 µG
Artikel-Nr:
(PRSI7121)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
7121
Lokale Artikelnummer::
PRSI7121
Beschreibung:
TSPY1L Antibody: Testis-specific protein on Y chromosome (TSPY1) is an ampliconic gene on the Y chromosome that has been associated with gonadoblastoma. Recent experiments have shown that in androgen-dependent testicular germ-cell tumors, TSPY1 can repress the androgen-bound androgen receptor (AR), a member of the nuclear steroid hormone receptor family that acts as a ligand-inducible transcription factor, suggesting that TSPY1 is a repressor of cell proliferation in germ-cell tumors and potentially in normal gonadal cells during early development. Two distinct isoforms of TSPY1, TSPY1L and TSPY1S, are known to exist.
VE:
1 * 100 µG
Artikel-Nr:
(PRSI60-391)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
60-391
Lokale Artikelnummer::
PRSI60-391
Beschreibung:
For WB starting dilution is: 1:1000.
VE:
1 * 400 µl
Artikel-Nr:
(PRSI79-645)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
79-645
Lokale Artikelnummer::
PRSI79-645
Beschreibung:
Transcription factor that binds to the octamer motif (5'-ATTTGCAT-3'). Forms a trimeric complex with SOX2 on DNA and controls the expression of a number of genes involved in embryonic development such as YES1, FGF4, UTF1 and ZFP206. Critical for early embryogenesis and for embryonic stem cell pluripotency
VE:
1 * 100 µG
Artikel-Nr:
(PRSI79-637)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
79-637
Lokale Artikelnummer::
PRSI79-637
Beschreibung:
Blue light-dependent regulator of the circadian feedback loop. Inhibits CLOCK|NPAS2-ARNTL E box-mediated transcription. Acts, in conjunction with CRY2, in maintaining period length and circadian rhythmicity. Has no photolyase activity. Capable of translocating circadian clock core proteins such as PER proteins to the nucleus. May inhibit CLOCK|NPAS2-ARNTL transcriptional activity through stabilizing the unphosphorylated form of ARNTL
VE:
1 * 100 µG
Artikel-Nr:
(PRSI61-643)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
61-643
Lokale Artikelnummer::
PRSI61-643
Beschreibung:
For WB starting dilution is: 1:1000. For IHC-P starting dilution is: 1:50~100. For FACS starting dilution is: 1:10~50.
VE:
1 * 400 µl
Artikel-Nr:
(PRSI76-831)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
76-831
Lokale Artikelnummer::
PRSI76-831
Beschreibung:
The HP-3G10 monoclonal antibody specifically binds to an 80 kDa homodimer type II membrane glycoprotein from the C-type lectin superfamily, known as the human CD161 or NKR-P1A. CD161 is expressed on most natural killer cells, subsets of CD4+ and CD8+ T lymphocytes, gamma delta TCR T lymphocytes, a subset of CD3+ thymocytes, and especially on CD45RO+ T lymphocytes. Reports indicate that it may serve as a specific receptor for some natural killer cell targets and a possible stimulatory role.
VE:
1 * 0,1 mg
Artikel-Nr:
(PRSI27-597)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
27-597
Lokale Artikelnummer::
PRSI27-597
Beschreibung:
LHX3 is a member a large protein family which carry the LIM domain, a unique cysteine-rich zinc-binding domain. The encoded protein is a transcription factor that is required for pituitary development and motor neuron specification. Mutations in this gene have been associated with a syndrome of combined pituitary hormone deficiency and rigid cervical spine. Two transcripts variants encoding distinct isoforms have been identified for this gene.
VE:
1 * 100 µG
Preis auf Anfrage
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