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tert-Butyl-4-chlor-2-fluorbenzoat
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tert-Butyl-4-chlor-2-fluorbenzoat
Artikel-Nr:
(BNUM1152-50)
Lieferant:
Biotium
Hersteller-Artikelnummer::
BNUM1152-50
Lokale Artikelnummer::
BTIUBNUM1152-50
Beschreibung:
This antibody recognizes a 45 kDa protein, which is identified as isocitrate dehydrogenase (IDH1). It belongs to the isocitrate and isopropylmalate dehydrogenases family. IDH1 catalyzes the third step of the citric acid cycle, which involves the oxidative decarboxylation of isocitrate, formingalpha-ketoglutarate and CO2 in a two-step reaction. The first step involves the oxidation of isocitrate to the intermediate oxalosuccinate, while the second step involves the production ofalpha-ketoglutarate. During this process, either NADH or NADPH is produced along with CO2. Recently, an inactivating mutation of IDH1 has been implicated in glioblastoma. IDH1 appears to function as a tumor suppressor that, when mutationally inactivated, contributes to tumorigenesis in part through induction of the HIF-1 pathway.
VE:
1 * 50 µl
Artikel-Nr:
(APOSBIB1402-250MG)
Lieferant:
APOLLO SCIENTIFIC
Hersteller-Artikelnummer::
BIB1402-250MG
Lokale Artikelnummer::
APOSBIB1402-250MG
Beschreibung:
5-Bromo-4-chloro-3-indolyl α-D-mannopyranoside
VE:
1 * 250 mg
Lieferant:
APOLLO SCIENTIFIC
Beschreibung:
6-Chloro-1,2-benzoxazol-3-amine 98%
Artikel-Nr:
(BLDPBD159700-1G)
Lieferant:
BLD PHARMATECH GMBH
Hersteller-Artikelnummer::
BD159700-1G
Lokale Artikelnummer::
BLDPBD159700-1G
Beschreibung:
2-Chloro-5-(trifluoromethyl)nicotinic acid 98%
VE:
1 * 1 g
Artikel-Nr:
(BLDPBD628831-25G)
Lieferant:
BLD PHARMATECH GMBH
Hersteller-Artikelnummer::
BD628831-25G
Lokale Artikelnummer::
BLDPBD628831-25G
Beschreibung:
4-Chloro-2-(trifluoroacetyl)aniline hydrochloride 97%
VE:
1 * 25 g
Lieferant:
APOLLO SCIENTIFIC
Beschreibung:
Ethyl-2-chloro-2-(hydroxyimino)acetate 97%
Lieferant:
APOLLO SCIENTIFIC
Beschreibung:
2-Chloro-N-[4-(trifluoromethyl)phenyl]acetamide 97%
Artikel-Nr:
(APOSOR13671-250MG)
Lieferant:
APOLLO SCIENTIFIC
Hersteller-Artikelnummer::
OR13671-250MG
Lokale Artikelnummer::
APOSOR13671-250MG
Beschreibung:
5-Chloro-3-(2-hydroxyethyl)-1H-indole 95%
VE:
1 * 250 mg
Artikel-Nr:
(BOSSBS-12144R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12144R-A555
Lokale Artikelnummer::
BOSSBS-12144R-A555
Beschreibung:
Src homology 2 (SH2) domains bind specifically to tyrosine-phosphorylated proteins that temporally participate in signal transduction events (1). Shc-like protein (Sck) is a neuronal adaptor protein that contains an N-terminal PTB (phosphotyrosine binding) domain, a collagen homology (CH) domain, and a conserved C-terminal SH2 domain (2,3). Human Sck transcripts are present at high levels in liver, pancreas, prostate and ovary (4,5). In vascular endothelial cells, Sck participates in VEGF-induced signal transduction (6). Treatment of human umbilical vein endothelial (HUVEC) cells with VEGF induces recruitment of Sck to tyrosine-1175 of the kinase insert domain-containing receptor (KDR) and enhances Sck tyrosine phosphorylation (7,8).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-12144R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12144R-A647
Lokale Artikelnummer::
BOSSBS-12144R-A647
Beschreibung:
Src homology 2 (SH2) domains bind specifically to tyrosine-phosphorylated proteins that temporally participate in signal transduction events (1). Shc-like protein (Sck) is a neuronal adaptor protein that contains an N-terminal PTB (phosphotyrosine binding) domain, a collagen homology (CH) domain, and a conserved C-terminal SH2 domain (2,3). Human Sck transcripts are present at high levels in liver, pancreas, prostate and ovary (4,5). In vascular endothelial cells, Sck participates in VEGF-induced signal transduction (6). Treatment of human umbilical vein endothelial (HUVEC) cells with VEGF induces recruitment of Sck to tyrosine-1175 of the kinase insert domain-containing receptor (KDR) and enhances Sck tyrosine phosphorylation (7,8).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9716R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9716R-A555
Lokale Artikelnummer::
BOSSBS-9716R-A555
Beschreibung:
Chromosome 10 contains over 800 genes and 135 million nucleotides, making up nearly 4.5% of the human genome. PTEN is an important tumor suppressor gene located on chromosome 10 and, when defective, causes a genetic predisposition to cancer development known as Cowden syndrome. The chromosome 10 encoded gene ERCC6 is important for DNA repair and is linked to Cockayne syndrome which is characterized by extreme photosensitivity and premature aging. Tetrahydrobiopterin deficiency and a number of syndromes involving defective skull and facial bone fusion are also linked to chromosome 10. As with most trisomies, trisomy 10 is rare and is deleterious. The KIAA1279 gene product has been provisionally designated KIAA1279 pending further characterization.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9716R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9716R-A488
Lokale Artikelnummer::
BOSSBS-9716R-A488
Beschreibung:
Chromosome 10 contains over 800 genes and 135 million nucleotides, making up nearly 4.5% of the human genome. PTEN is an important tumor suppressor gene located on chromosome 10 and, when defective, causes a genetic predisposition to cancer development known as Cowden syndrome. The chromosome 10 encoded gene ERCC6 is important for DNA repair and is linked to Cockayne syndrome which is characterized by extreme photosensitivity and premature aging. Tetrahydrobiopterin deficiency and a number of syndromes involving defective skull and facial bone fusion are also linked to chromosome 10. As with most trisomies, trisomy 10 is rare and is deleterious. The KIAA1279 gene product has been provisionally designated KIAA1279 pending further characterization.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9769R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9769R-A750
Lokale Artikelnummer::
BOSSBS-9769R-A750
Beschreibung:
C10orf62 is a 223 amino acid protein encoded by a gene that maps to human chromosome 10q24.1. Spanning nearly 135 million base pairs, chromosome 10 makes up approximately 4.5% of total DNA in cells and encodes nearly 1200 genes. Several protein-coding genes, including those that encode for chemokines, cadherins, excision repair proteins, early growth response factors (Egrs) and fibroblast growth receptors (FGFRs), are located on chromosome 10. Defects in some of the genes that map to chromosome 10 are associated with Charcot-Marie Tooth disease, Jackson-Weiss syndrome, Usher syndrome, nonsyndromatic deafness, Wolman's syndrome, Cowden syndrome, multiple endocrine neoplasia type 2 and porphyria.
VE:
1 * 100 µl
Lieferant:
APOLLO SCIENTIFIC
Beschreibung:
Ethyl 4-chloro-2-(thien-2-yl)pyrimidine-5-carboxylate
Lieferant:
APOLLO SCIENTIFIC
Beschreibung:
4-Chloro-2-(dimethylamino)-1,3-thiazole-5-carbaldehyde 95%
Artikel-Nr:
(APOSOR931181-1G)
Lieferant:
APOLLO SCIENTIFIC
Hersteller-Artikelnummer::
OR931181-1G
Lokale Artikelnummer::
APOSOR931181-1G
Beschreibung:
2-Chloro-1-(pyridin-3-yl)ethanone hydrochloride 95%
VE:
1 * 1 g
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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