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2\'-Amino-4\',5\'-dimethoxyacetophenon
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2\'-Amino-4\',5\'-dimethoxyacetophenon
Artikel-Nr:
(BOSSBS-13138R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13138R-A750
Lokale Artikelnummer::
BOSSBS-13138R-A750
Beschreibung:
Fanconi anemia (FA) is an autosomal recessive disorder characterized by bone marrow failure, birth defects and chromosomal instability. At the cellular level, FA is characterized by spontaneous chromosomal breakage and a unique hypersensitivity to DNA cross-linking agents. At least eight complementation groups (A-G) have been identified and six FA genes (for subtypes A, C, D2, E, F and G) have been cloned. The FA proteins lack sequence homologies or motifs that could point to a molecular function. The cellular accumulation of FA proteins, including FANCA and FANCG, is subject to regulation by TNF alpha signaling. Phosphorylation of FANC (Fanconi anemia complementation group) proteins is thought to be important for the function of the FA pathway. FANCA, also known as FACA and FANCH, associates with the Brm-related gene 1 (BRG1) product, a subunit of the SWI/SNF complex which remodels chromatin structure through a DNA-dependent ATPase activity. FANCA is mainly expressed in lymphoid tissues, testis and ovary. The amino-terminal region of the FANCA protein is required for FANCG binding, FANCC binding, nuclear localization and functional activity of the complex. The human FANCA gene maps to chromosome 16q24.3 and encodes a 1,455 amino acid protein.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-8341R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-8341R-CY7
Lokale Artikelnummer::
BOSSBS-8341R-CY7
Beschreibung:
CPXM (carboxypeptidase X, member 1) belongs to the peptidase M14 family. However, no carboxypeptidase activity has yet been detected. It may be involved in cell-cell interactions.Members of the M14 metallocarboxypeptidase protein family serve many diverse functions and are divided into three subfamilies based on structure, function and amino acid sequence similarity. Belonging to the N/E subfamily, CPXM (metallocarboxypeptidase CPX-1) is a 734 amino acid protein that contains a F5/8 type C domain and likely binds one zinc ion per subunit. Most members of the N/E subfamily contain several domains, including an active carboxypeptidase domain and signal peptide, and are thought to function mostly in protein-protein interactions and/or protein-membrane interactions, thereby targeting the protein to specific locations within the secretory pathway. CPXM is a unique member of this subfamily in that it does not appear to exhibit any enzymatic activity due to lack of several active-site residues that are present in the catalytic domain of other members of the N/E subfamily. Studies showing that CPXM expression is regulated during osteoclastogenesis suggest that CPXM may play a role in osteoclast differentiation. There are two isoforms of CPXM which are a result of alternative splicing events.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-15486R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-15486R-CY5
Lokale Artikelnummer::
BOSSBS-15486R-CY5
Beschreibung:
Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. The majority of Zinc-finger proteins contain a Kr_ppel-type DNA binding domain and a KRAB domain, which is thought to interact with KAP1, thereby recruiting histone modifying proteins. HIC-2 (hypermethylated in cancer 2) possesses Zinc finger motifs that are thought to be important for DNA-binding and also has a BTB/POZ domain at the N-terminus, which is thought to be important for protein-protein binding, as well as for the binding of transcription factors. HIC-2 is also known as Hic-3, HIC1-related gene on chromosome 22 or Zinc finger and BTB domain-containing protein 30, and is a 615 amino acid protein that is expressed as two isoforms produced by alternative splicing. HIC-2 is highly expressed in cerebellum and is localised to the nucleus in cells. HIC-2 contains a short amino acid sequence that is thought to interact with CtBP, a transcriptional repressor. The gene sequence associated with HIC-2 is thought to be a target for miRNAs (microRNAs) which are expressed in many cancers, suggesting that HIC-2 could possess tumor suppressor capabilities.
VE:
1 * 100 µl
Artikel-Nr:
(SPCMAM156-200LTBL)
Lieferant:
Spectrum Chemical
Hersteller-Artikelnummer::
AM156-200LTBL
Lokale Artikelnummer::
SPCMAM156-200LTBL
Beschreibung:
2-Amino-2-methyl-1-propanol, or aminomethyl propanol is a colourless, viscous liquid that functions as a pH adjuster. It is also used as an intermediate in drug synthetic schemes.
VE:
1 * 200 L
Artikel-Nr:
(BOSSBS-11174R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11174R-CY3
Lokale Artikelnummer::
BOSSBS-11174R-CY3
Beschreibung:
KY peptidase (Kyphoscoliosis peptidase) is a 561 amino acid cytoskeleton protease that interacts with several sarcomeric cytoskeletal proteins, including Filamin 2. KY peptidase probably plays a role in the maturation, function and stabilization of the neuromuscular junction. KY-null mouse mutants exhibit distinct irregular subceullular Filamin 2 localization, suggesting that KY peptidase deficiency may be the cause of several types of limb-girdle muscular dystrophies.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11174R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11174R-CY5
Lokale Artikelnummer::
BOSSBS-11174R-CY5
Beschreibung:
KY peptidase (Kyphoscoliosis peptidase) is a 561 amino acid cytoskeleton protease that interacts with several sarcomeric cytoskeletal proteins, including Filamin 2. KY peptidase probably plays a role in the maturation, function and stabilization of the neuromuscular junction. KY-null mouse mutants exhibit distinct irregular subceullular Filamin 2 localization, suggesting that KY peptidase deficiency may be the cause of several types of limb-girdle muscular dystrophies.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-10150R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-10150R-CY3
Lokale Artikelnummer::
BOSSBS-10150R-CY3
Beschreibung:
The protein encoded by this gene belongs to the acyl-CoA dehydrogenase family, which is a family of mitochondrial flavoenzymes involved in fatty acid and branched chain amino-acid metabolism. This protein is one of the four enzymes that catalyze the initial step of mitochondrial beta-oxidation of straight-chain fatty acid. Defects in this gene are the cause of long-chain acyl-CoA dehydrogenase (LCAD) deficiency, leading to nonketotic hypoglycemia. [provided by RefSeq].
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-0957R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0957R
Lokale Artikelnummer::
BOSSBS-0957R
Beschreibung:
This gene encodes a protein containing three zinc finger domains and a nuclear localization signal. The mRNA and the protein of this gene are upregulated by wildtype p53 and overexpression of this gene inhibits tumor cell growth, suggesting that this gene may have a role in the p53-dependent growth regulatory pathway. Alternative splicing of this gene results in two transcript variants encoding two isoforms differing in only one amino acid.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5015R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5015R-CY7
Lokale Artikelnummer::
BOSSBS-5015R-CY7
Beschreibung:
The protein encoded by this gene belongs to the acyl-CoA dehydrogenase family, which is a family of mitochondrial flavoenzymes involved in fatty acid and branched chain amino-acid metabolism. This protein is one of the four enzymes that catalyze the initial step of mitochondrial beta-oxidation of straight-chain fatty acid. Defects in this gene are the cause of long-chain acyl-CoA dehydrogenase (LCAD) deficiency, leading to nonketotic hypoglycemia. [provided by RefSeq].
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-1384R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1384R-A555
Lokale Artikelnummer::
BOSSBS-1384R-A555
Beschreibung:
Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy. Cleaves the C-terminal amino acid of ATG8 family proteins MAP1LC3, GABARAPL1, GABARAPL2 and GABARAP, to reveal a C-terminal glycine. Exposure of the glycine at the C-terminus is essential for ATG8 proteins conjugation to phosphatidylethanolamine (PE) and insertion to membranes, which is necessary for autophagy. Has also an activity of delipidating enzyme for the PE-conjugated forms.
VE:
1 * 100 µl
Lieferant:
Thermo Scientific
Beschreibung:
4-Amino-3-hydroxy-1-naphthalinsulfonsäure 90+% ACS
Artikel-Nr:
(BOSSBS-13351R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13351R-A488
Lokale Artikelnummer::
BOSSBS-13351R-A488
Beschreibung:
This gene is a member of a gene family that encodes enzymes involved in both the metabolism of glutathione and in the transpeptidation of amino acids. Changes in the activity of gamma-glutamyltransferase may signal preneoplastic or toxic conditions in the liver or kidney. The protein encoded by this gene consists of a heavy and a light chain, and it can interact with CT120, a plasma membrane-associated protein that is possibly involved in lung carcinogenesis. [provided by RefSeq, Jul 2008].
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-4030R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-4030R-HRP
Lokale Artikelnummer::
BOSSBS-4030R-HRP
Beschreibung:
Pancreatic amylase is a digestive enzyme secreted by the pancreas. It consists of a single polypeptide chain with a molecular weight of 54 kDa.Pancreatic amylase and salivary amylase are the products of separate genes and, although they share 98% amino acid sequence homology, they differ in molecular size, isoelectric point and antigenic properties. Measurement of amylase concentrations in serum is a diagnostic test for various pancreatic disorders (especially acute and relapsing pancreatitis).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11161R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11161R-FITC
Lokale Artikelnummer::
BOSSBS-11161R-FITC
Beschreibung:
PCDHGC5 (protocadherin gamma-C5) is a 944 amino acid single-pass type I membrane protein that contains six cadherin domains and exists as two alternatively spliced isoforms. As a potential calcium-dependent cell-adhesion protein, PCDHGC5 may be involved in the establishment and maintenance of specific neuronal connections in the brain. The gene that encodes PCDHGC5 consists of approximately 23,739 bases and maps to human chromosome 5q31.3.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-13351R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13351R-A350
Lokale Artikelnummer::
BOSSBS-13351R-A350
Beschreibung:
This gene is a member of a gene family that encodes enzymes involved in both the metabolism of glutathione and in the transpeptidation of amino acids. Changes in the activity of gamma-glutamyltransferase may signal preneoplastic or toxic conditions in the liver or kidney. The protein encoded by this gene consists of a heavy and a light chain, and it can interact with CT120, a plasma membrane-associated protein that is possibly involved in lung carcinogenesis. [provided by RefSeq, Jul 2008].
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-10459R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-10459R-A350
Lokale Artikelnummer::
BOSSBS-10459R-A350
Beschreibung:
This gene is a member of a gene family that encodes enzymes involved in both the metabolism of glutathione and in the transpeptidation of amino acids. Changes in the activity of gamma-glutamyltransferase may signal preneoplastic or toxic conditions in the liver or kidney. The protein encoded by this gene consists of a heavy and a light chain, and it can interact with CT120, a plasma membrane-associated protein that is possibly involved in lung carcinogenesis. [provided by RefSeq, Jul 2008].
VE:
1 * 100 µl
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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