2\'-Deoxyuridine-5\'-triphosphate+trisodium+salt
Artikel-Nr:
(SIAL25114-1KG)
Lieferant:
Sigma-Aldrich
Hersteller-Artikelnummer::
25114-1KG
Lokale Artikelnummer::
SIAL25114-1KG
Beschreibung:
tri-Natriumcitrat 5,5-Hydrat, Sigma-Aldrich®
VE:
1 * 1 kg
Artikel-Nr:
(BOSSBS-0136R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0136R-A680
Lokale Artikelnummer::
BOSSBS-0136R-A680
Beschreibung:
GTP cyclohydrolase I (also designated dopa-responsive dystonia) catalyses the conversion of GTP to D-erythro-7,8-dihydroneopterin triphosphate, the first and rate-limiting step in tetrahydrobiopterin (BH4) biosynthesis. Tetrahydrobiopterin is an essential cofactor for 3 aromatic amino acid monooxygenases: phenylalanine, tyrosine, and tryptophan hydroxylases. Animals can synthesise tetrahydrobiopterin in vivo from GTP through several enzymatic reactions.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-0136R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0136R-CY3
Lokale Artikelnummer::
BOSSBS-0136R-CY3
Beschreibung:
GTP cyclohydrolase I (also designated dopa-responsive dystonia) catalyzes the conversion of GTP to D-erythro-7,8-dihydroneopterin triphosphate, the first and rate-limiting step in tetrahydrobiopterin (BH4) biosynthesis. Tetrahydrobiopterin is an essential cofactor for 3 aromatic amino acid monooxygenases: phenylalanine, tyrosine, and tryptophan hydroxylases. Animals can synthesize tetrahydrobiopterin in vivo from GTP through several enzymatic reactions.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-0136R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0136R
Lokale Artikelnummer::
BOSSBS-0136R
Beschreibung:
GTP cyclohydrolase I (also designated dopa-responsive dystonia) catalyzes the conversion of GTP to D-erythro-7,8-dihydroneopterin triphosphate, the first and rate-limiting step in tetrahydrobiopterin (BH4) biosynthesis. Tetrahydrobiopterin is an essential cofactor for 3 aromatic amino acid monooxygenases: phenylalanine, tyrosine, and tryptophan hydroxylases. Animals can synthesize tetrahydrobiopterin in vivo from GTP through several enzymatic reactions.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5749R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5749R
Lokale Artikelnummer::
BOSSBS-5749R
Beschreibung:
Deoxycytidine kinase is responsible for the phosphorylation of several deoxyribonucleosides and their analogs. Deficiency of this enzyme activity is associated with resistance to antiviral and anticancer chemotherapeutic agents, whereas increased enzyme activity is associated with increased activation of these compounds to cytotoxic nucleoside triphosphate derivatives. It is the rate limiting enzyme in the activation of many important anticancer and retroviral drugs and its activity is often decreased in cells that are resistant to cytosine arabinoside.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-7750R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-7750R-CY3
Lokale Artikelnummer::
BOSSBS-7750R-CY3
Beschreibung:
Mitotic kinesin required for chromosome passenger complex (CPC)-mediated cytokinesis. Following phosphorylation by PLK1, involved in recruitment of PLK1 to the central spindle. Interacts with guanosine triphosphate (GTP)-bound forms of RAB6A and RAB6B. May act as a motor required for the retrograde RAB6 regulated transport of Golgi membranes and associated vesicles along microtubules. Has a microtubule plus end-directed motility.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-7617R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-7617R
Lokale Artikelnummer::
BOSSBS-7617R
Beschreibung:
Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate. Inhibitor of p53-induced apoptosis.Tissue specificity: Expressed at a moderately low level in many tissues. Most abundant in kidney, prostate, ovary, intestine, and spleen.
VE:
1 * 100 µl
Lieferant:
Sigma-Aldrich
Beschreibung:
tri-Natriumphosphat, Sigma-Aldrich®
Artikel-Nr:
(BOSSBS-0993R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0993R-HRP
Lokale Artikelnummer::
BOSSBS-0993R-HRP
Beschreibung:
Innate immune receptor which acts as a cytoplasmic sensor of viral nucleic acids and plays a major role in sensing viral infection and in the activation of a cascade of antiviral responses including the induction of type I interferons and proinflammatory cytokines. Its ligands include: 5'-triphosphorylated ssRNA and dsRNA and short dsRNA (<1 kb in length). In addition to the 5'-triphosphate moiety, blunt-end base pairing at the 5'-end of the RNA is very essential. Overhangs at the non-triphosphorylated end of the dsRNA RNA have no major impact on its activity. A 3'overhang at the 5'triphosphate end decreases and any 5'overhang at the 5' triphosphate end abolishes its activity. Upon ligand binding it associates with mitochondria antiviral signaling protein (MAVS/IPS1) which activates the IKK-related kinases: TBK1 and IKBKE which phosphorylate interferon regulatory factors: IRF3 and IRF7 which in turn activate transcription of antiviral immunological genes, including interferons (IFNs); IFN-alpha and IFN-beta. Detects both positive and negative strand RNA viruses including members of the families Paramyxoviridae: Human respiratory syncytial virus and measles virus (MeV), Rhabdoviridae: vesicular stomatitis virus (VSV), Orthomyxoviridae: influenza A and B virus, Flaviviridae: Japanese encephalitis virus (JEV), hepatitis C virus (HCV), dengue virus (DENV) and west Nile virus (WNV). It also detects rotavirus and reovirus. Also involved in antiviral signaling in response to viruses containing a dsDNA genome such as Epstein-Barr virus (EBV). Detects dsRNA produced from non-self dsDNA by RNA polymerase III, such as Epstein-Barr virus-encoded RNAs (EBERs). May play important roles in granulocyte production and differentiation, bacterial phagocytosis and in the regulation of cell migration.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-0993R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0993R
Lokale Artikelnummer::
BOSSBS-0993R
Beschreibung:
Innate immune receptor which acts as a cytoplasmic sensor of viral nucleic acids and plays a major role in sensing viral infection and in the activation of a cascade of antiviral responses including the induction of type I interferons and proinflammatory cytokines. Its ligands include: 5'-triphosphorylated ssRNA and dsRNA and short dsRNA (<1 kb in length). In addition to the 5'-triphosphate moiety, blunt-end base pairing at the 5'-end of the RNA is very essential. Overhangs at the non-triphosphorylated end of the dsRNA RNA have no major impact on its activity. A 3'overhang at the 5'triphosphate end decreases and any 5'overhang at the 5' triphosphate end abolishes its activity. Upon ligand binding it associates with mitochondria antiviral signaling protein (MAVS/IPS1) which activates the IKK-related kinases: TBK1 and IKBKE which phosphorylate interferon regulatory factors: IRF3 and IRF7 which in turn activate transcription of antiviral immunological genes, including interferons (IFNs); IFN-alpha and IFN-beta. Detects both positive and negative strand RNA viruses including members of the families Paramyxoviridae: Human respiratory syncytial virus and measles virus (MeV), Rhabdoviridae: vesicular stomatitis virus (VSV), Orthomyxoviridae: influenza A and B virus, Flaviviridae: Japanese encephalitis virus (JEV), hepatitis C virus (HCV), dengue virus (DENV) and west Nile virus (WNV). It also detects rotavirus and reovirus. Also involved in antiviral signaling in response to viruses containing a dsDNA genome such as Epstein-Barr virus (EBV). Detects dsRNA produced from non-self dsDNA by RNA polymerase III, such as Epstein-Barr virus-encoded RNAs (EBERs). May play important roles in granulocyte production and differentiation, bacterial phagocytosis and in the regulation of cell migration.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-0993R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0993R-A647
Lokale Artikelnummer::
BOSSBS-0993R-A647
Beschreibung:
Innate immune receptor which acts as a cytoplasmic sensor of viral nucleic acids and plays a major role in sensing viral infection and in the activation of a cascade of antiviral responses including the induction of type I interferons and proinflammatory cytokines. Its ligands include: 5'-triphosphorylated ssRNA and dsRNA and short dsRNA (<1 kb in length). In addition to the 5'-triphosphate moiety, blunt-end base pairing at the 5'-end of the RNA is very essential. Overhangs at the non-triphosphorylated end of the dsRNA RNA have no major impact on its activity. A 3'overhang at the 5'triphosphate end decreases and any 5'overhang at the 5' triphosphate end abolishes its activity. Upon ligand binding it associates with mitochondria antiviral signaling protein (MAVS/IPS1) which activates the IKK-related kinases: TBK1 and IKBKE which phosphorylate interferon regulatory factors: IRF3 and IRF7 which in turn activate transcription of antiviral immunological genes, including interferons (IFNs); IFN-alpha and IFN-beta. Detects both positive and negative strand RNA viruses including members of the families Paramyxoviridae: Human respiratory syncytial virus and measles virus (MeV), Rhabdoviridae: vesicular stomatitis virus (VSV), Orthomyxoviridae: influenza A and B virus, Flaviviridae: Japanese encephalitis virus (JEV), hepatitis C virus (HCV), dengue virus (DENV) and west Nile virus (WNV). It also detects rotavirus and reovirus. Also involved in antiviral signaling in response to viruses containing a dsDNA genome such as Epstein-Barr virus (EBV). Detects dsRNA produced from non-self dsDNA by RNA polymerase III, such as Epstein-Barr virus-encoded RNAs (EBERs). May play important roles in granulocyte production and differentiation, bacterial phagocytosis and in the regulation of cell migration.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-0136R-CY5.5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0136R-CY5.5
Lokale Artikelnummer::
BOSSBS-0136R-CY5.5
Beschreibung:
GTP cyclohydrolase I (also designated dopa-responsive dystonia) catalyzes the conversion of GTP to D-erythro-7,8-dihydroneopterin triphosphate, the first and rate-limiting step in tetrahydrobiopterin (BH4) biosynthesis. Tetrahydrobiopterin is an essential cofactor for 3 aromatic amino acid monooxygenases: phenylalanine, tyrosine, and tryptophan hydroxylases. Animals can synthesize tetrahydrobiopterin in vivo from GTP through several enzymatic reactions.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-7750R-CY5.5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-7750R-CY5.5
Lokale Artikelnummer::
BOSSBS-7750R-CY5.5
Beschreibung:
Mitotic kinesin required for chromosome passenger complex (CPC)-mediated cytokinesis. Following phosphorylation by PLK1, involved in recruitment of PLK1 to the central spindle. Interacts with guanosine triphosphate (GTP)-bound forms of RAB6A and RAB6B. May act as a motor required for the retrograde RAB6 regulated transport of Golgi membranes and associated vesicles along microtubules. Has a microtubule plus end-directed motility.
VE:
1 * 100 µl
Lieferant:
Alfa Aesar
Beschreibung:
tri-Natriumphosphat Dodecahydrat 98,0-102,0% ACS
Artikel-Nr:
(BOSSBS-0136R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0136R-FITC
Lokale Artikelnummer::
BOSSBS-0136R-FITC
Beschreibung:
GTP cyclohydrolase I (also designated dopa-responsive dystonia) catalyzes the conversion of GTP to D-erythro-7,8-dihydroneopterin triphosphate, the first and rate-limiting step in tetrahydrobiopterin (BH4) biosynthesis. Tetrahydrobiopterin is an essential cofactor for 3 aromatic amino acid monooxygenases: phenylalanine, tyrosine, and tryptophan hydroxylases. Animals can synthesize tetrahydrobiopterin in vivo from GTP through several enzymatic reactions.
VE:
1 * 100 µl
Preis auf Anfrage
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