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Artikel-Nr:
(BOSSBS-8577R-CY5.5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-8577R-CY5.5
Lokale Artikelnummer::
BOSSBS-8577R-CY5.5
Beschreibung:
GPKOW is a potential RNA-binding protein consisting of one central G patch domain and two C-terminal KOW domains. T54 is a 476 amino acid protein belonging to the MOS2 family. It is a mammalian homolog of the Arabidopsis thaliana MOS2 (modifier of SNC1, 2) nuclear protein that is required for innate immunity. Similar to A. thaliana MOS2, T54 localizes to the nucleus and contains G patch and KOW domains, suggesting that T54 may play a similar role in mammalian innate immunity.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5713R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5713R-CY3
Lokale Artikelnummer::
BOSSBS-5713R-CY3
Beschreibung:
HOXA5 upregulates both p53 promoter-reporter constructs and endogenous p53 synthesis, leading to apoptosis. HOXA5 is detectable in approximately one-third of primary tumors. Lack of HOXA5 expression strongly correlates with methylation of its promoter region, suggesting a causal role for methylation in the silencing of HOXA5 gene expression. HOXA5 expression is an important step in tumorigenesis and loss of expression of p53 in human breast cancer may be primarily due to lack of expression of HOXA5.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-8577R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-8577R-CY5
Lokale Artikelnummer::
BOSSBS-8577R-CY5
Beschreibung:
GPKOW is a potential RNA-binding protein consisting of one central G patch domain and two C-terminal KOW domains. T54 is a 476 amino acid protein belonging to the MOS2 family. It is a mammalian homolog of the Arabidopsis thaliana MOS2 (modifier of SNC1, 2) nuclear protein that is required for innate immunity. Similar to A. thaliana MOS2, T54 localizes to the nucleus and contains G patch and KOW domains, suggesting that T54 may play a similar role in mammalian innate immunity.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-0437R-CY5.5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0437R-CY5.5
Lokale Artikelnummer::
BOSSBS-0437R-CY5.5
Beschreibung:
Streptavidin is biotin-binding protein that was originally isolated from Streptomyces avidinii. In contrast to avidin, streptavidin has no carbohydrate and has a mildly acidic pI of 5. Streptavidin products use a recombinant form of streptavidin having a mass of 53,000 daltons and a near-neutral pI. Streptavidin is a tetrameric protein, with each subunit binding one molecule of biotin with affinity similar to that of avidin. Guanidinium chloride will dissociate avidin and streptavidin into subunits, but streptavidin is more resistant to dissociation.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-13475R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13475R-CY3
Lokale Artikelnummer::
BOSSBS-13475R-CY3
Beschreibung:
Glucosamine 6-phosphate N-acetyltransferase (GNA1), also designated phosphoglucosamine transacetylase or phosphoglucosamine acetylase, belongs to the GNA1 subfamily of the larger acetyltransferase family of proteins. GNA1, a peripheral membrane protein containing one N-acetyltransferase domain, is expressed in the colon and maps to cytoband 14q22.1. The protein localizes to the Golgi apparatus and the endosome. It is important for UDP-GlcNAc biosynthesis pathway. GNA1 catalyzes the synthesis of GlcNAc6P from AcCoA and GlcN6P, a step in the UDP-GlcNAc6P formation pathway.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-0039R-CY5.5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0039R-CY5.5
Lokale Artikelnummer::
BOSSBS-0039R-CY5.5
Beschreibung:
The activity dependent neuroprotective protein (ADNP) gene is frequently amplified in many neoplasias, including breast, bladder, ovarian, pancreatic, and colon cancers. ADNP mRNA is abundantly expressed in distinct normal tissues, and high expression levels were encountered in malignant cells. ADNP is implicated in maintaining cell survival, perhaps through modulation of p53. The encoded protein contains one homeobox and nine zinc finger domains, suggesting that it functions as a transcription factor.
VE:
1 * 100 µl
Lieferant:
Biotium
Beschreibung:
This antibody cocktail recognizes three melanoma-specific proteins, which include MART-1, Tyrosinase and gp100. MART-1 is a newly identified melanocyte differentiation antigen recognized by autologous cytotoxic T lymphocytes. Tyrosinase is one of the targets for cytotoxic T-cell recognition in melanoma patients. Function of gp100 is not known but it is reported to be a useful marker for melanocytes and melanomas. This cocktail of three markers is designed for extremely sensitive labeling of formalin-fixed, paraffin-embedded melanomas and other tumors showing melanocytic differentiation.
Lieferant:
Biotium
Beschreibung:
This antibody cocktail recognizes three melanoma-specific proteins, which include MART-1, Tyrosinase and gp100. MART-1 is a newly identified melanocyte differentiation antigen recognized by autologous cytotoxic T lymphocytes. Tyrosinase is one of the targets for cytotoxic T-cell recognition in melanoma patients. Function of gp100 is not known but it is reported to be a useful marker for melanocytes and melanomas. This cocktail of three markers is designed for extremely sensitive labeling of formalin-fixed, paraffin-embedded melanomas and other tumors showing melanocytic differentiation.
Artikel-Nr:
(BOSSBS-7903R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-7903R-A750
Lokale Artikelnummer::
BOSSBS-7903R-A750
Beschreibung:
AKAP associated sperm protein (encoded by the gene ROPN1L) is a sperm protein which interacts with A-kinase anchoring protein, AKAP3, through the amphipathic helix region of AKAP3. The Type II regulatory subunit of cAMP-dependent protein kinase (PKARII) also binds to this helical domain of AKAP3, allowing PKARII to be targeted to specific subcellular compartments. It is suggested that sperm contains several proteins that bind to AKAPs in a manner similar to PKARII, and this encoded protein may be one of them.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5144R-CY5.5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5144R-CY5.5
Lokale Artikelnummer::
BOSSBS-5144R-CY5.5
Beschreibung:
This gene is a member of the natriuretic peptide family and encodes a secreted protein which functions as a cardiac hormone. The protein undergoes two cleavage events, one within the cell and a second after secretion into the blood. The protein's biological actions include natriuresis, diuresis, vasorelaxation, inhibition of renin and aldosterone secretion, and a key role in cardiovascular homeostasis. A high concentration of this protein in the bloodstream is indicative of heart failure. Mutations in this gene have been associated with postmenopausal osteoporosis. [provided by RefSeq].
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-6420R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6420R-HRP
Lokale Artikelnummer::
BOSSBS-6420R-HRP
Beschreibung:
This gene encodes one member of a family of translation repressor proteins. The protein directly interacts with eukaryotic translation initiation factor 4E (eIF4E), which is a limiting component of the multisubunit complex that recruits 40S ribosomal subunits to the 5' end of mRNAs. Interaction of this protein with eIF4E inhibits complex assembly and represses translation. This protein is phosphorylated in response to various signals including UV irradiation and insulin signaling, resulting in its dissociation from eIF4E and activation of mRNA translation. [provided by RefSeq, Jul 2008].
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-12278R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12278R-A555
Lokale Artikelnummer::
BOSSBS-12278R-A555
Beschreibung:
SOHLH1 is a 328 amino acid protein that localizes to both the nucleus and the cytoplasm and contains one bHLH domain through which it may function as a transcription factor during oogenesis and spermatogenesis. The gene encoding SOHLH1 maps to human chromosome 9, which houses over 900 genes and comprises nearly 4% of the human genome. Hereditary hemorrhagic telangiectasia, which is characterized by harmful vascular defects, and Familial dysautonomia, are both associated with chromosome 9. Notably, chromosome 9 encompasses the largest interferon family gene cluster.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-12278R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12278R-FITC
Lokale Artikelnummer::
BOSSBS-12278R-FITC
Beschreibung:
SOHLH1 is a 328 amino acid protein that localizes to both the nucleus and the cytoplasm and contains one bHLH domain through which it may function as a transcription factor during oogenesis and spermatogenesis. The gene encoding SOHLH1 maps to human chromosome 9, which houses over 900 genes and comprises nearly 4% of the human genome. Hereditary hemorrhagic telangiectasia, which is characterized by harmful vascular defects, and Familial dysautonomia, are both associated with chromosome 9. Notably, chromosome 9 encompasses the largest interferon family gene cluster.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-0317R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0317R-A647
Lokale Artikelnummer::
BOSSBS-0317R-A647
Beschreibung:
Receptor-proximal protein kinase regulating integrin-mediated signal transduction. May act as a mediator of inside-out integrin signaling. Focal adhesion protein part of the complex ILK-PINCH. This complex is considered to be one of the convergence points of integrin- and growth factor-signaling pathway. Could be implicated in mediating cell architecture, adhesion to integrin substrates and anchorage-dependent growth in epithelial cells. Phosphorylates beta-1 and beta-3 integrin subunit on serine and threonine residues, but also AKT1 and GSK3B.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9577R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9577R-A350
Lokale Artikelnummer::
BOSSBS-9577R-A350
Beschreibung:
TSPEAR, also known as C21orf9, is a 669 amino acid secreted protein. Expressed as two isoforms produced by alternative splicing, TSPEAR contains one Thrombospondin N-terminal domain and seven EAR (epilepsy-associated repeat) domains. EAR domains are found in several proteins, including TSPEAR, encoded by genes that map within chromosome regions associated with seizure disorders. It is thought that the EAR domain plays a role in the pathogenesis of epilepsy by either binding to an unknown epileptic ligand or interfering with axon synaptogenesis.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-8435R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-8435R-A488
Lokale Artikelnummer::
BOSSBS-8435R-A488
Beschreibung:
BXDC1 is a 306 amino acid protein encoded by the human gene BXDC1. BXDC1 is a nuclear protein that contains one Brix domain. Brix domain containing proteins represent a family of proteins involved in the biogenesis of large ribosomal subunits. The Brix domain is a region with homology to the yeast protein Pitx1 (Ribosome biogenesis protein BRX1). Pitx1 is part of a complex that includes RPF1, RPF2 and SSF1 or SSF2. This complex is required for the biogenesis of the 60S ribosomal subunit.
VE:
1 * 100 µl
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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