3-(tert-Butyldimethylsiloxy)thiophenol
Artikel-Nr:
(BOSSBS-5304R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5304R-CY3
Lokale Artikelnummer::
BOSSBS-5304R-CY3
Beschreibung:
Separase is a cysteine protease that is essential for mitotic progression by separating sister chromatids. Each cell must receive one chromatid of every chromosome, during mitosis. Cohesin plays an important role in cohering sister chromatids during the prophase through anaphase stages of mitosis, making certain that genomic information is replicated accurately. As the cellular division process continues, separase destroys cohesin by means of cleavage, allowing the chromatids to separate and divide with the cell. Separase activity is highly regulated. It not only cleaves cohesin at the onset of anaphase but also cleaves itself, promoting downregulation of separase after anaphase. Should a human cell become an aneuploid (one too many or too few chromatids), the embryo most likely will not survive. Should the embryo survive, it will most likely develop severe birth defects or later develop malignant cancers.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9025R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9025R-A750
Lokale Artikelnummer::
BOSSBS-9025R-A750
Beschreibung:
The leucine-rich (LRR) repeat is a 20-30 amino acid motif that forms a hydrophobic å/ horseshoe fold, allowing it to accommodate several leucine residues within a tightly packed core. All LRR repeats contain a variable segment and a highly conserved segment, the latter of which accounts for 11 or 12 residues of the entire LRR motif. ISLR2 (immunoglobulin superfamily containing leucine-rich repeat 2), also known as LINX (leucine-rich repeat domain and immunoglobulin domain-containing axon extension protein), is a 745 amino acid single-pass membrane protein that contains five LRR repeats, one Ig-like (immunoglobulin-like) domain, a LRRCT domain and one LRRNT domain. ISLR2 exists as a homomultimer and is essential for axon extension during neural development. The gene encoding ISLR2 maps to human chromosome 15q24.1.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9617R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9617R
Lokale Artikelnummer::
BOSSBS-9617R
Beschreibung:
C14orf174, is a 674 amino acid protein that contains one SAM (sterile alpha motif) domain. Existing as two alternatively spliced isoforms,C14orf174 is encoded by a gene that maps to human chromosome 14q24.3. Chromosome 14 contains about 700 genes and 106 million base pairs and makes up about 3.5% of human cellular DNA. Chromosome 14 encodes the presinilin 1 (PSEN1) gene, which is one of the three key genes associated with the development of Alzheimer's disease. The SERPINA1 gene is located on chromosome 14 and when defective leads to the genetic disorder ?-antitrypsin deficiency. This disorder is characterized by severe lung complications and liver dysfunction. Notably, the immunoglobulin heavy chain locus is found on chromosome 14 and has been identified as a fusion with the chromosome 19 encoded protein Bcl-3 in the (14;19) translocations found in a variety of B cell malignancies.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-8641R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-8641R-A647
Lokale Artikelnummer::
BOSSBS-8641R-A647
Beschreibung:
Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. ZDHHC1 (zinc finger, DHHC-type containing 1), also known as ZNF377 (zinc finger protein 377) or C16orf1, is a 485 amino acid multi-pass membrane protein that contains one DHHC-type zinc finger. Expressed in fetal heart, lung and kidney and also present in adult lung and pancreas, ZDHHC1 functions as a palmitoyltransferase that catalyzes the conversion of palmitoyl-CoA and protein-cysteine to S-palmitoyl protein and CoA. Like ZDHHC1, ZDHHC5, ZDHHC6, ZDHHC7 and ZDHHC18 each contain one DHHC-type zinc finger through which they convey palmitoyltransferase activity against a broad range of substrates, including H-Ras, SNAP 25 and GABAA R proteins.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3347R-CY5.5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3347R-CY5.5
Lokale Artikelnummer::
BOSSBS-3347R-CY5.5
Beschreibung:
Endocrine gland-derived vascular endothelial growth factor (EG-VEGF) induces proliferation, migration, and fenestration in capillary endothelial cells derived from endocrine glands. EG-VEGF possesses an HIF-1 binding site; its expression is induced by hypoxia and restricted to the steroidogenic glands (ovary, testis, adrenal and placenta). Expression of EG-VEGF is often complementary to the expression of VEGF, suggesting that these molecules function in a coordinated manner. EG-VEGF is an example of a class of highly specific mitogens that act to regulate proliferation and differentiation of the vascular endothelium in a tissue-specific manner. It is expressed primarily in one type of tissue and acts selectively on one type of endothelium. EG-VEGF, possibly through binding to a G protein-coupled receptor, results in the activation of MAPK p44/42 and phosphatidylinositol 3-kinase signaling pathways, leading to proliferation, migration and survival of responsive endothelial cells .
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-8496R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-8496R-CY7
Lokale Artikelnummer::
BOSSBS-8496R-CY7
Beschreibung:
RFESD, also known as Rieske domain-containing protein, is a 157 amino acid protein that binds one 2Fe-2S cluster per subunit. Involved in metal ion binding, RFESD contains one Rieske domain. The RFESD gene is conserved in chimpanzee, dog, cow, mouse, rat, chicken and zebrafish, and maps to human chromosome 5q15. Chromosome 5 makes up approximately 6% of the human genome and contains 181 million base pairs, which encode 1,000 genes. Chromosome 5 is associated with Cockayne syndrome through the ERCC8 gene and familial adenomatous polyposis through the adenomatous polyposis coli (APC) tumor suppressor gene. Treacher Collins syndrome is caused by insertions or deletions within the TCOF1 gene and is also associated with chromosome 5. Deletion of 5q or chromosome 5 altogether is common in therapy-related acute myelogenous leukemias and myelodysplastic syndrome.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-0241R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0241R-CY3
Lokale Artikelnummer::
BOSSBS-0241R-CY3
Beschreibung:
The attachment of enveloped viruses to cells and the fusion of viral and cellular membranes are critical early events in the HIV viral infection. This process is mediated by envelope glycoproteins (gp) on the surface of the virus. The human immunodeficiency virus type 1 (HIV-1) envelope glycoprotein, gp160, is proteolytically cleaved into gp120 and gp41, which remain noncovalently associated with one another. gp120 is one of the proteins that forms the envelope of HIV. gp120 projects from the surface of HIV and binds to the CD4 molecule on helper T cells. gp120 has been a logical experimental HIV vaccine because the outer envelope is the first part of the virus that encounters antibody. gp41 is embedded in the outer envelope of HIV that anchors gp120. gp41 also plays a key role in HIV's infection of CD4+ T cells by facilitating the fusion of the viral and cell membranes. The nomenclature of the gp proteins describes their respective molecular masses (e.g., gp160, gp120, gp41).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11067R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11067R
Lokale Artikelnummer::
BOSSBS-11067R
Beschreibung:
Beta-tectorin is a 329 amino acid secreted protein that contains one zona pellucida (ZP) domain. While it may form homomeric filaments after self-association, Beta-tectorin may also form heteromeric filaments when it associates with ?tectorin. The presence of a hydrophobic C-terminus preceded by a potential cleavage site strongly suggests that tectorins are synthesized as glycosylphosphatidylinositol-linked, membrane-bound precursors. Tectorins are targeted to the apical surface of the inner ear epithelia and proteolytically released into the extracellular compartment. Beta-tectorin is one of the major non-collagenous components of the tectorial membrane. The tectorial membrane is an extracellular matrix of the inner ear that covers the neuroepithelium of the cochlea and contacts the stereocilia bundles of specialized sensory hair cells. Sound induces movement of these hair cells relative to the tectorial membrane, deflects the stereocilia and leads to fluctuations in hair-cell membrane potential, transducing sound into electrical signals.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-7983R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-7983R
Lokale Artikelnummer::
BOSSBS-7983R
Beschreibung:
The protein encoded by this gene is one of several isozymes of carbonic anhydrase. This protein is found only in salivary glands and saliva and protein may play a role in the reversible hydratation of carbon dioxide though its function in saliva is unknown. [provided by RefSeq, Jul 2008].
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-13573R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13573R-A647
Lokale Artikelnummer::
BOSSBS-13573R-A647
Beschreibung:
ZBTB39 may be involved in transcriptional regulation. It belongs to the krueppel C2H2-type zinc-finger protein family and contains one BTB (POZ) domain and eight C2H2-type zinc fingers.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3834R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3834R-A488
Lokale Artikelnummer::
BOSSBS-3834R-A488
Beschreibung:
MRPL12 is a component of the 39S subunit of mammalian mitochondrial ribosomes. This protein forms homodimers whereas in prokaryotic ribosomes two L7/L12 dimers and one L10 protein form the L8 protein complex.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3834R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3834R-FITC
Lokale Artikelnummer::
BOSSBS-3834R-FITC
Beschreibung:
MRPL12 is a component of the 39S subunit of mammalian mitochondrial ribosomes. This protein forms homodimers whereas in prokaryotic ribosomes two L7/L12 dimers and one L10 protein form the L8 protein complex.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3834R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3834R-A647
Lokale Artikelnummer::
BOSSBS-3834R-A647
Beschreibung:
MRPL12 is a component of the 39S subunit of mammalian mitochondrial ribosomes. This protein forms homodimers whereas in prokaryotic ribosomes two L7/L12 dimers and one L10 protein form the L8 protein complex.
VE:
1 * 100 µl
Lieferant:
Sartorius
Beschreibung:
Gelatine membrane filters in conjunction with the MD8 air samplers (gelatine filter method) are used for the collection of airborne microbes and viruses. These filters are completely water-soluble, therefore, microbes in one sample can be cultivated in different nutrient media or low and high bacteria counts can be measured.
Lieferant:
VWR Collection
Beschreibung:
ChromasterUltra Rs ist das Ergebnis von jahrelanger Forschung, Entwicklung und Erfahrung. Herausgekommen ist eines der fortschrittlichsten, robustesten und benutzerfreundlichsten UHPLC-Systeme, das auf dem heutigen Markt verfügbar ist. Hitachi-High Technologies ist ein weltweit führendes Unternehmen in den Bereichen 'Fluid Control' und Optical Analysis Technology sowie 'High Performance Electronics'. Hitachi konzentriert sich darauf, das Wissen aus diesen drei Bereichen zu kombinieren, um der Welt der Chromatographie eines der besten Instrumente für die heutigen Anforderungen bereitzustellen. Zur Vereinbarung einer Vorführung mit einem unserer Experten wenden Sie sich bitte per E-Mail an chromatography@eu.vwr.com.
Lieferant:
APOLLO SCIENTIFIC
Beschreibung:
1-(3-Acetylphenyl)-3,3-dimethyl-2-azetanone 95%
Preis auf Anfrage
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