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5-Fluoro-2-(trifluoromethyl)benzenesulphonyl+chloride
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5-Fluoro-2-(trifluoromethyl)benzenesulphonyl+chloride
Lieferant:
APOLLO SCIENTIFIC
Beschreibung:
1-Brom-3,3-dimethylbutanon 97+%
Lieferant:
APOLLO SCIENTIFIC
Beschreibung:
2',4'-Dichlor-5'-fluoracetophenon 98%
Artikel-Nr:
(BOSSBS-6377R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6377R-A680
Lokale Artikelnummer::
BOSSBS-6377R-A680
Beschreibung:
Suppressin, also known as DEAF1 is a transcription factor required for embryonic development. Suppressin contains one SAND domain and one C-terminal MYND-type zinc finger. It interacts with LMO4 and CLIM-2, suggesting that it plays a role mediating cell fate and embryonic pattern formation. Suppressin is expressed in a variety of tissues and localises to the nucleus. Several isoforms exist due to alternative splicing and, depending on the isoform, Suppressin is secreted in some cell types. Secreted Suppressin can function to inhibit cell proliferation, arresting cells in the G0 or G1 phase. Mutations in the gene encoding Suppressin may result in a growth advantage leading to the development and progression of neoplasia. This suggest that Supressin is a potential target for cancer therapy.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-13573R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13573R-A647
Lokale Artikelnummer::
BOSSBS-13573R-A647
Beschreibung:
ZBTB39 may be involved in transcriptional regulation. It belongs to the krueppel C2H2-type zinc-finger protein family and contains one BTB (POZ) domain and eight C2H2-type zinc fingers.
VE:
1 * 100 µl
Artikel-Nr:
(APOSOR480679-25G)
Lieferant:
APOLLO SCIENTIFIC
Hersteller-Artikelnummer::
OR480679-25G
Lokale Artikelnummer::
APOSOR480679-25G
Beschreibung:
6-Brom-2-hydroxypyridin 97%
VE:
1 * 25 g
Artikel-Nr:
(BOSSBS-13496R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13496R-A555
Lokale Artikelnummer::
BOSSBS-13496R-A555
Beschreibung:
Glycosylphosphatidylinositol (GPI) acts as a membrane anchor for cell surface proteins. Glycosylphosphatidylinositol anchor attachment 1 protein (GPAA1), also designated GPI anchor attachment protein 1 or GAA1 protein homolog, is a membrane protein localized to the endoplasmic reticulum which is involved in GPI-anchor biosynthesis. GPAA1 is crucial for GPI-anchoring of precursor proteins and catalyzes the attachment of GPI to proteins containing a C-terminal GPR attachment signal. GAA1 contains an N-terminal signal sequence, one cAMP- and cGMP-dependent protein kinase phosphorylation site, two potential N-glycosylation sites, one leucine zipper pattern and eight putative transmembrane domains. GPAA1 is ubiquitously expressed and shows higher levels of expression in fetal tissues than in adult tissues.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-8386R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-8386R-HRP
Lokale Artikelnummer::
BOSSBS-8386R-HRP
Beschreibung:
CBLL1, also known as HAKAI (meaning ‘destruction’ in Japanese), or RNF188 (RING finger protein 188), is a 491 amino acid protein that contains one C2H2-type zinc finger and one RING-type zinc finger. CBLL1 is believed to function as an E3 ubiquitin-protein ligase that accepts a ubiquitin residue from an E2 ubiquitin-conjugating enzyme and immediately transfers that residue to a protein that is targeted for degradation. More specifically, upon activation of c-Src, CBLL1 interacts with and ubiquitinates tyrosine-phosphorylated E-cadherin, thereby targeting the E-cadherin complex for endocytosis and disrupting epithelial cell-cell contacts. Via its role as an E-cadherin regulator, CBLL1 participates in cell adhesion and may also be involved in the regulation of epithelial-mesenchymal transitions.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-0352R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0352R-A750
Lokale Artikelnummer::
BOSSBS-0352R-A750
Beschreibung:
Many vertebrate homeo box-containing genes have been identified on the basis of their sequence similarity with Drosophila developmental genes. Members of the Dlx gene family contain a homeobox that is related to that of Distal-less (Dll), a gene expressed in the head and limbs of the developing fruit fly. The Distal-less (Dlx) family of genes comprises at least 6 different members, DLX1-DLX6. The DLX proteins are postulated to play a role in forebrain and craniofacial development. Three transcript variants have been described for this gene, however, the full length nature of one variant has not been described. Studies of the two splice variants revealed that one encoded isoform functions as a repressor of the beta-globin gene while the other isoform lacks that function.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-15466R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-15466R-A647
Lokale Artikelnummer::
BOSSBS-15466R-A647
Beschreibung:
This endogenous retroviral envelope protein has retained its original fusogenic properties and participates in trophoblast fusion and the formation of a syncytium during placenta morphogenesis. The interaction with MFSD2A is apparently important for this process. Endogenous envelope proteins may have kept, lost or modified their original function during evolution but this one can still make pseudotypes with MLV, HIV-1 or SIV-1 virions and confer infectivity. Retroviral envelope proteins mediate receptor recognition and membrane fusion during early infection. The surface protein mediates receptor recognition, while the transmembrane protein anchors the envelope heterodimer to the viral membrane through one transmembrane domain. The other hydrophobic domain, called fusion peptide, mediates fusion of the viral membrane with the target cell membrane.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-13213R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13213R-A647
Lokale Artikelnummer::
BOSSBS-13213R-A647
Beschreibung:
FREM1 is a 2,179 amino acid protein that contains one C-type lectin domain, one Calx-beta domain and twelve CSPG repeats. Localized to the basement membrane of embryonic epidermal cells and secreted into extracellular space, FREM1 functions as an extracellular matrix protein that is essential for epidermal adhesion during embryogenesis and may also participate in epidermal differentiation. FREM1 exists as multiple alternatively spliced isoforms and is encoded by a gene which maps to human chromosome 9. Chromosome 9 contains 145 million base pairs and comprises 4% of the human genome, encoding nearly 900 genes. Hereditary hemorrhagic telangiectasia, which is characterized by harmful vascular defects, and Familial dysautonomia, are both associated with chromosome 9. Notably, chromosome 9 encompasses the largest interferon family gene cluster.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-13213R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13213R-A555
Lokale Artikelnummer::
BOSSBS-13213R-A555
Beschreibung:
FREM1 is a 2,179 amino acid protein that contains one C-type lectin domain, one Calx-beta domain and twelve CSPG repeats. Localized to the basement membrane of embryonic epidermal cells and secreted into extracellular space, FREM1 functions as an extracellular matrix protein that is essential for epidermal adhesion during embryogenesis and may also participate in epidermal differentiation. FREM1 exists as multiple alternatively spliced isoforms and is encoded by a gene which maps to human chromosome 9. Chromosome 9 contains 145 million base pairs and comprises 4% of the human genome, encoding nearly 900 genes. Hereditary hemorrhagic telangiectasia, which is characterized by harmful vascular defects, and Familial dysautonomia, are both associated with chromosome 9. Notably, chromosome 9 encompasses the largest interferon family gene cluster.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3834R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3834R-A488
Lokale Artikelnummer::
BOSSBS-3834R-A488
Beschreibung:
MRPL12 is a component of the 39S subunit of mammalian mitochondrial ribosomes. This protein forms homodimers whereas in prokaryotic ribosomes two L7/L12 dimers and one L10 protein form the L8 protein complex.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3834R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3834R-A647
Lokale Artikelnummer::
BOSSBS-3834R-A647
Beschreibung:
MRPL12 is a component of the 39S subunit of mammalian mitochondrial ribosomes. This protein forms homodimers whereas in prokaryotic ribosomes two L7/L12 dimers and one L10 protein form the L8 protein complex.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3834R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3834R-FITC
Lokale Artikelnummer::
BOSSBS-3834R-FITC
Beschreibung:
MRPL12 is a component of the 39S subunit of mammalian mitochondrial ribosomes. This protein forms homodimers whereas in prokaryotic ribosomes two L7/L12 dimers and one L10 protein form the L8 protein complex.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-13645R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13645R-CY7
Lokale Artikelnummer::
BOSSBS-13645R-CY7
Beschreibung:
IQSEC2 is a 1,478 amino acid protein that belongs to the BRAG family and contains one IQ domain, one PH domain and a SEC7 domain. Localizing to the cytoplasm, IQSEC2 is expressed in brain, kidney and small intestine, with weaker levels of expression in placenta, pancreas, ovary, prostate and liver. IQSEC2 is a component of the postsynaptic density at excitatory synapses, and interacts with ARF family members as a guanine nucleotide exchange factor. Through the activation of ARF substrates, IQSEC2 may play a crucial role in cytoskeletal and synaptic organization. The gene encoding IQSEC2 maps to the human X chromosome. Defects to the IQSEC2 gene have been linked to mental retardation X-linked type 1 (MRX1), a condition characterized by decreased intellectual function. IQSEC2 exists as three isoforms due to alternative splicing events.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11669R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11669R-CY3
Lokale Artikelnummer::
BOSSBS-11669R-CY3
Beschreibung:
The RING-type zinc finger motif is present in a number of viral and eukaryotic proteins and is made of a conserved cysteine-rich domain that is able to bind two zinc atoms. Proteins that contain this conserved domain are generally involved in the ubiquitination pathway of protein degradation. RNF146 (RING finger protein 146), also known as Dactylidin, is a 359 amino acid protein that contains one RING-type zinc finger and one WWE domain. Via its RING-type zinc finger, RNF146 may play a role in transcriptional regulation and protein degradation events. Defects in the gene encoding RNF146 are associated with Alzheimer's disease (AD) and may lead to a higher risk of breast cancer. Two isoforms of RNF146 exist due to alternative splicing events.
VE:
1 * 100 µl
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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