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1,2-Bis(4-chlorophenyl)ethylenediamine
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1,2-Bis(4-chlorophenyl)ethylenediamine
Artikel-Nr:
(PRSI92-631)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
92-631
Lokale Artikelnummer::
PRSI92-631
Beschreibung:
IL-12 is involved in the differentiation of naive T cells into Th1 cells. It is known as a T cell-stimulating factor, which can stimulate the growth and function of T cells. It stimulates the production of interferon-gamma (IFN- gamma ) and tumor necrosis factor-alpha (TNF- alpha) from T cells and natural killer (NK) cells, and reduces IL-4 mediated suppression of IFN- gamma . T cells that produce IL-12 have a coreceptor, CD30, which is associated with IL-12 activity. IL-12 plays an important role in the activities of natural killer cells and T lymphocytes. IL-12 mediates enhancement of the cytotoxic activity of NK cells and CD8+ cytotoxic T lymphocytes.
VE:
1 * 50 µG
Artikel-Nr:
(BOSSBS-10063R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-10063R
Lokale Artikelnummer::
BOSSBS-10063R
Beschreibung:
Lymphotoxin beta is a type II membrane protein of the TNF family. It anchors lymphotoxin-alpha to the cell surface through heterotrimer formation. The predominant form on the lymphocyte surface is the lymphotoxin-alpha 1/beta 2 complex and this complex is the primary ligand for the lymphotoxin-beta receptor. LTB is an inducer of the inflammatory response system and involved in normal development of lymphoid tissue. Lymphotoxin-beta isoform b is probably non-functional. Alternative splicing results in multiple transcript variants encoding different isoforms.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5347R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5347R
Lokale Artikelnummer::
BOSSBS-5347R
Beschreibung:
The protein encoded by this gene is a component of the multi-subunit protein complex EIF4F. This complex facilitates the recruitment of mRNA to the ribosome, which is a rate-limiting step during the initiation phase of protein synthesis. The recognition of the mRNA cap and the ATP-dependent unwinding of 5'-terminal secondary structure is catalyzed by factors in this complex. The subunit encoded by this gene is a large scaffolding protein that contains binding sites for other members of the EIF4F complex. A domain at its N-terminus can also interact with the poly(A)-binding protein, which may mediate the circularization of mRNA during translation. Alternative splicing results in multiple transcript variants, some of which are derived from alternative promoter usage. [provided by RefSeq].eIF4G1 (eukaryotic translation Initiation Factor 4 Gamma 1) is a component of the protein complex eIF-4 which is involved in the recognition of the mRNA cap ATP-dependent unwinding of the 5'-terminal secondary structure and recruitment of mRNA to the ribosome. eIF4G plays a critical role in protein expression and is at the center of a complex regulatory network. Together with the cap-binding protein eIF4E, it recruits the small ribosomal subunit to the 5'-end of mRNA and promotes the assembly of a functional translation initiation complex which scans along the mRNA to the translation start codon. Human eIF4G contains three consecutive HEAT domains, as well as long unstructured regions involved in multiple protein-protein interactions. The interactions of eIF4G1 with other factors are largely unknown.
VE:
1 * 100 µl
Artikel-Nr:
(PRSI76-574)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
76-574
Lokale Artikelnummer::
PRSI76-574
Beschreibung:
The 2.4G2 monoclonal antibody specifically reacts with an epitope on the extracellular domain of the mouse CD16 (Fc gamma III) and CD 32 (Fc gamma II). CD16 and CD32 are low affinity receptors for the IgG Fc domain and are expressed by B lymphocytes, NK cells, kupffer cells, mast cells, monocytes, macrophages, granulocytes, immature thymocytes, neutrophils, and some activated mature T cells.The 2.4G2 antibody blocks the binding of immunoglobulins to CD16 and CD32, and possibly to Fc gamma I receptor.
VE:
1 * 0,5 mg
New Product
Artikel-Nr:
(BOSSBS-6457R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6457R-A680
Lokale Artikelnummer::
BOSSBS-6457R-A680
Beschreibung:
This receptor binds insulin-like growth factor with a high affinity. It has tyrosine kinase activity. The insulin-like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival.
VE:
1 * 100 µl
Artikel-Nr:
(NOVUNBP1-72795)
Lieferant:
Novus Biologicals
Hersteller-Artikelnummer::
NBP1-72795
Lokale Artikelnummer::
NOVUNBP1-72795
Beschreibung:
Rabbit Polyclonal Rabbit anti-Mouse IgG2b Antibody. Tested Applications: Western Blot, ELISA, Immunohistochemistry. Tested Reactivity: Mouse.
VE:
1 * 1 mg
Artikel-Nr:
(BOSSBS-5717R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5717R-CY5
Lokale Artikelnummer::
BOSSBS-5717R-CY5
Beschreibung:
Inhibitor of the Wnt signaling pathway. Down-regulates beta-catenin. Probably facilitate the phosphorylation of beta-catenin and APC by GSK3B (By similarity).
VE:
1 * 100 µl
Lieferant:
Alfa Aesar
Beschreibung:
3-Brom-2-(brommethyl)propansäure 98%
Lieferant:
BIOLEGEND INC
Beschreibung:
Anti-IFN-gamma Mouse Monoclonal Antibody [clone: 4S.B3] (APC (Allophycocyanin)/FIRE™750)
Artikel-Nr:
(BWRLBS1576)
Lieferant:
Bioworld Technology
Hersteller-Artikelnummer::
BS1576
Lokale Artikelnummer::
BWRLBS1576
Beschreibung:
Synthetic peptide, corresponding to amino acids 160-210 of Human PKAalpha.
VE:
1 * 100 µG
Lieferant:
APOLLO SCIENTIFIC
Beschreibung:
3-Pyridon
Artikel-Nr:
(SERA39777.01)
Lieferant:
Serva
Hersteller-Artikelnummer::
39777.01
Lokale Artikelnummer::
SERA39777.01
Beschreibung:
γ-(N-Morpholino)propansulfonsäure (MOPS)
VE:
1 * 100 g
 This is a MarketSource item. Additional charges may apply
Artikel-Nr:
(BOSSBS-9548R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9548R-CY5
Lokale Artikelnummer::
BOSSBS-9548R-CY5
Beschreibung:
Mammalian protein farnesyl transferases are heterodimeric proteins containing two nonidentical Alpha and beta subunits that attach farnesyl residues to a cysteine at the fourth position from the COOH terminus of several proteins, including nuclear lamins and p21Ras proteins. The natural substrates contain the Cys-A-A-Xaa recognition sequence, where the A residues are aliphatic and Xaa represents methionine, serine, glutamine or cysteine. The purified farnesyl transferase is an a-b heterodimer. The beta subunit, which is known as FT beta, CAAX farnesyltransferase subunit beta, or Ras proteins prenyltransferase subunit beta, is a 437 amino acid protein that contains five PFTB repeats and binds the peptide substrate. The Alpha subunit is suspected to participate in formation of a stable complex with the substrate farnesyl pyrophosphate.
VE:
1 * 100 µl
Lieferant:
Alfa Aesar
Beschreibung:
4-Fluoro-trans-β-styrylboronic acid pinacol ester 97%
Artikel-Nr:
(BOSSBS-5717R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5717R-A350
Lokale Artikelnummer::
BOSSBS-5717R-A350
Beschreibung:
Inhibitor of the Wnt signaling pathway. Down-regulates beta-catenin. Probably facilitate the phosphorylation of beta-catenin and APC by GSK3B (By similarity).
VE:
1 * 100 µl
Lieferant:
Alfa Aesar
Beschreibung:
trans-β-Styrylboronic acid pinacol ester ≥98%
Preis auf Anfrage
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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