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[4-(2-Fluorophenoxy)phenyl]methanol
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[4-(2-Fluorophenoxy)phenyl]methanol
Artikel-Nr:
(BOSSBS-1091R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1091R-A555
Lokale Artikelnummer::
BOSSBS-1091R-A555
Beschreibung:
Constitutive NADPH oxidase which generates superoxide intracellularly upon formation of a complex with CYBA/p22phox. Regulates signaling cascades probably through phosphatases inhibition. May function as an oxygen sensor regulating the KCNK3/TASK-1 potassium channel and HIF1A activity. May regulate insulin signaling cascade. May play a role in apoptosis, bone resorption and lipolysaccharide-mediated activation of NFKB.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-1091R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1091R-FITC
Lokale Artikelnummer::
BOSSBS-1091R-FITC
Beschreibung:
Constitutive NADPH oxidase which generates superoxide intracellularly upon formation of a complex with CYBA/p22phox. Regulates signaling cascades probably through phosphatases inhibition. May function as an oxygen sensor regulating the KCNK3/TASK-1 potassium channel and HIF1A activity. May regulate insulin signaling cascade. May play a role in apoptosis, bone resorption and lipolysaccharide-mediated activation of NFKB.
VE:
1 * 100 µl
Artikel-Nr:
(USBI037305-PE)
Lieferant:
US Biological
Hersteller-Artikelnummer::
037305-PE
Lokale Artikelnummer::
USBI037305-PE
Beschreibung:
Anti-KCND1 Rabbit Polyclonal Antibody (PE (Phycoerythrin))
VE:
1 * 200 µl
Artikel-Nr:
(USBI037302-PE)
Lieferant:
US Biological
Hersteller-Artikelnummer::
037302-PE
Lokale Artikelnummer::
USBI037302-PE
Beschreibung:
Anti-KCNC2 Rabbit Polyclonal Antibody (PE (Phycoerythrin))
VE:
1 * 200 µl
Artikel-Nr:
(USBI037297-AP)
Lieferant:
US Biological
Hersteller-Artikelnummer::
037297-AP
Lokale Artikelnummer::
USBI037297-AP
Beschreibung:
Anti-KCNA6 Rabbit Polyclonal Antibody (AP (Alkaline Phosphatase))
VE:
1 * 200 µl
Artikel-Nr:
(BOSSBS-0236R-CY5.5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0236R-CY5.5
Lokale Artikelnummer::
BOSSBS-0236R-CY5.5
Beschreibung:
The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. Primary transducing effect is adenylate cyclase inhibition. Signaling promotes phospholipase C activity, leading to the release of inositol trisphosphate (IP3); this then triggers calcium ion release into the cytosol.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-1850R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1850R-A750
Lokale Artikelnummer::
BOSSBS-1850R-A750
Beschreibung:
Receptor for both mineralocorticoids (MC) such as aldosterone and glucocorticoids (GC) such as corticosterone or cortisol. Binds to mineralocorticoid response elements (MRE) and transactivates target genes. The effect of MC is to increase ion and water transport and thus raise extracellular fluid volume and blood pressure and lower potassium levels.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-1850R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1850R-CY3
Lokale Artikelnummer::
BOSSBS-1850R-CY3
Beschreibung:
Receptor for both mineralocorticoids (MC) such as aldosterone and glucocorticoids (GC) such as corticosterone or cortisol. Binds to mineralocorticoid response elements (MRE) and transactivates target genes. The effect of MC is to increase ion and water transport and thus raise extracellular fluid volume and blood pressure and lower potassium levels.
VE:
1 * 100 µl
Artikel-Nr:
(SIAL396532-1G)
Lieferant:
Sigma-Aldrich
Hersteller-Artikelnummer::
396532-1G
Lokale Artikelnummer::
SIAL396532-1G
Beschreibung:
2,2,2-Trifluorethanol-[D3], Sigma-Aldrich®
VE:
1 * 1 g
Artikel-Nr:
(BOSSBS-11528R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11528R-A647
Lokale Artikelnummer::
BOSSBS-11528R-A647
Beschreibung:
GALR3 a 368 and 370 amino acid protein in human and rat, respectively, belongs to a family of G protein-coupled receptors that bind the neuropeptide galanin, which is distributed throughout the central and peripheral nervous system, the pituitary gland, the gastrointestinal tract and in the endocrine and exocrine pancreas. GALR3 mRNA is widely distributed, but expressed at low abundance. In human, GALR3 mRNA is highly expressed in the hypothalamus, pituitary and testis, and is expressed to a lesser extent in adrenal gland and pancreas. Rat and human GALR3 co-express with potassium channel subunits GIRK1 and GIRK4. Like GALR1, GALR3 signaling pathways lead to the inhibition of adenylate cyclase and to the activation of potassium channels, which are linked to the regulation of neurotransmitter release. Binding of galanin to galanin receptors results in increased feeding, impaired learning, enhanced opiate analgesia and decreased opiate place preference.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11528R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11528R-HRP
Lokale Artikelnummer::
BOSSBS-11528R-HRP
Beschreibung:
GALR3 a 368 and 370 amino acid protein in human and rat, respectively, belongs to a family of G protein-coupled receptors that bind the neuropeptide galanin, which is distributed throughout the central and peripheral nervous system, the pituitary gland, the gastrointestinal tract and in the endocrine and exocrine pancreas. GALR3 mRNA is widely distributed, but expressed at low abundance. In human, GALR3 mRNA is highly expressed in the hypothalamus, pituitary and testis, and is expressed to a lesser extent in adrenal gland and pancreas. Rat and human GALR3 co-express with potassium channel subunits GIRK1 and GIRK4. Like GALR1, GALR3 signaling pathways lead to the inhibition of adenylate cyclase and to the activation of potassium channels, which are linked to the regulation of neurotransmitter release. Binding of galanin to galanin receptors results in increased feeding, impaired learning, enhanced opiate analgesia and decreased opiate place preference.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11528R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11528R-A750
Lokale Artikelnummer::
BOSSBS-11528R-A750
Beschreibung:
GALR3 a 368 and 370 amino acid protein in human and rat, respectively, belongs to a family of G protein-coupled receptors that bind the neuropeptide galanin, which is distributed throughout the central and peripheral nervous system, the pituitary gland, the gastrointestinal tract and in the endocrine and exocrine pancreas. GALR3 mRNA is widely distributed, but expressed at low abundance. In human, GALR3 mRNA is highly expressed in the hypothalamus, pituitary and testis, and is expressed to a lesser extent in adrenal gland and pancreas. Rat and human GALR3 co-express with potassium channel subunits GIRK1 and GIRK4. Like GALR1, GALR3 Signalling pathways lead to the inhibition of adenylate cyclase and to the activation of potassium channels, which are linked to the regulation of neurotransmitter release. Binding of galanin to galanin receptors results in increased feeding, impaired learning, enhanced opiate analgesia and decreased opiate place preference.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-1293R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1293R-A350
Lokale Artikelnummer::
BOSSBS-1293R-A350
Beschreibung:
Component of a heterodimeric G-protein coupled receptor for GABA, formed by GABBR1 and GABBR2. Within the heterodimeric GABA receptor, only GABBR1 seems to bind agonists, while GABBR2 mediates coupling to G proteins. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling inhibits adenylate cyclase, stimulates phospholipase A2, activates potassium channels, inactivates voltage-dependent calcium-channels and modulates inositol phospholipid hydrolysis. Plays a critical role in the fine-tuning of inhibitory synaptic transmission. Pre-synaptic GABA receptor inhibits neurotransmitter release by down-regulating high-voltage activated calcium channels, whereas postsynaptic GABA receptor decreases neuronal excitability by activating a prominent inwardly rectifying potassium (Kir) conductance that underlies the late inhibitory postsynaptic potentials. Not only implicated in synaptic inhibition but also in hippocampal long-term potentiation, slow wave sleep, muscle relaxation and antinociception.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-1293R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1293R-HRP
Lokale Artikelnummer::
BOSSBS-1293R-HRP
Beschreibung:
Component of a heterodimeric G-protein coupled receptor for GABA, formed by GABBR1 and GABBR2. Within the heterodimeric GABA receptor, only GABBR1 seems to bind agonists, while GABBR2 mediates coupling to G proteins. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling inhibits adenylate cyclase, stimulates phospholipase A2, activates potassium channels, inactivates voltage-dependent calcium-channels and modulates inositol phospholipid hydrolysis. Plays a critical role in the fine-tuning of inhibitory synaptic transmission. Pre-synaptic GABA receptor inhibits neurotransmitter release by down-regulating high-voltage activated calcium channels, whereas postsynaptic GABA receptor decreases neuronal excitability by activating a prominent inwardly rectifying potassium (Kir) conductance that underlies the late inhibitory postsynaptic potentials. Not only implicated in synaptic inhibition but also in hippocampal long-term potentiation, slow wave sleep, muscle relaxation and antinociception.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-1293R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1293R-A647
Lokale Artikelnummer::
BOSSBS-1293R-A647
Beschreibung:
Component of a heterodimeric G-protein coupled receptor for GABA, formed by GABBR1 and GABBR2. Within the heterodimeric GABA receptor, only GABBR1 seems to bind agonists, while GABBR2 mediates coupling to G proteins. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling inhibits adenylate cyclase, stimulates phospholipase A2, activates potassium channels, inactivates voltage-dependent calcium-channels and modulates inositol phospholipid hydrolysis. Plays a critical role in the fine-tuning of inhibitory synaptic transmission. Pre-synaptic GABA receptor inhibits neurotransmitter release by down-regulating high-voltage activated calcium channels, whereas postsynaptic GABA receptor decreases neuronal excitability by activating a prominent inwardly rectifying potassium (Kir) conductance that underlies the late inhibitory postsynaptic potentials. Not only implicated in synaptic inhibition but also in hippocampal long-term potentiation, slow wave sleep, muscle relaxation and antinociception.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-13028R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13028R
Lokale Artikelnummer::
BOSSBS-13028R
Beschreibung:
Dipeptidyl peptidases (DPPs) mediate regulatory activity of their substrates and have been linked to a variety of diseases including type 2 diabetes, obesity and cancer. DPPs have post-proline dipeptidyl aminopeptidase activity, cleaving Xaa-Pro dipeptides from the N-termini of proteins. DPPs can bind specific voltage-gated potassium channels and alter their expression and biophysical properties and may also influence T cells. DPP proteins include DPRP1, DPRP2, DPP3, DPP7, DPP10, DPPX and CD26. DPP10 (dipeptidyl-peptidase 10), also known as DPRP3 (dipeptidyl peptidase IV-related protein 3), DPL2 or DPPY, is a non-functional dipeptidyl peptidase which can bind to the potassium channels KV4.1 and KV4.2. It is a single-pass type II membrane protein expressed in spinal cord, adrenal glands, pancreas and brain tissues and may act as a modulator for cell surface expression and activity of KV4.1 and KV4.2.
VE:
1 * 100 µl
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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