Tetrakis(dimethylamino)zirkonium(IV)
Lieferant:
Alfa Aesar
Beschreibung:
Natriumsulfit, wasserfrei 98%
Artikel-Nr:
(PRSI92-190)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
92-190
Lokale Artikelnummer::
PRSI92-190
Beschreibung:
Syntaxin-8 is a single-pass type IV membrane protein which belongs to the syntaxin family. It contains one t-SNARE coil homology domain. STX8 is highly expressed in heart, also found in brain, kidney, liver, lung, placenta, skeletal muscle, spleen and pancreas. STX8 is involved in protein trafficking from early to late endosomes via vesicle fusion and exocytosis. It as a vesicle trafficking protein functions in the early secretory pathway, possibly mediating retrograde transport form cis-golgi membrane to the ER.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI29-801)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
29-801
Lokale Artikelnummer::
PRSI29-801
Beschreibung:
Cytochrome c oxidase (COX) is the terminal enzyme of the mitochondrial respiratory chain. It is a multi-subunit enzyme complex that couples the transfer of electrons from cytochrome c to molecular oxygen and contributes to a proton electrochemical gradient across the inner mitochondrial membrane. The complex consists of 13 mitochondrial- and nuclear-encoded subunits. The mitochondrially-encoded subunits perform the electron transfer and proton pumping activities. The functions of the nuclear-encoded subunits are unknown but they may play a role in the regulation and assembly of the complex. COX4I1 is the nuclear-encoded subunit IV isoform 1 of the human mitochondrial respiratory chain enzyme.Cytochrome c oxidase (COX) is the terminal enzyme of the mitochondrial respiratory chain. It is a multi-subunit enzyme complex that couples the transfer of electrons from cytochrome c to molecular oxygen and contributes to a proton electrochemical gradient across the inner mitochondrial membrane. The complex consists of 13 mitochondrial- and nuclear-encoded subunits. The mitochondrially-encoded subunits perform the electron transfer and proton pumping activities. The functions of the nuclear-encoded subunits are unknown but they may play a role in the regulation and assembly of the complex. This gene encodes the nuclear-encoded subunit IV isoform 1 of the human mitochondrial respiratory chain enzyme. It is located at the 3' of the NOC4 (neighbor of COX4) gene in a head-to-head orientation, and shares a promoter with it.
VE:
1 * 100 µG
Artikel-Nr:
(BSBTPB9047)
Lieferant:
BosterBio
Hersteller-Artikelnummer::
PB9047
Lokale Artikelnummer::
BSBTPB9047
Beschreibung:
Polyclonal antibody for Cathepsin D/CTSD detection. Host: Rabbit.Size: 100μg/vial. Tested applications: IHC-P. Reactive species: Human. Cathepsin D/CTSD information: Molecular Weight: 44552 MW; Subcellular Localization: Lysosome. Melanosome. Secreted, extracellular space. Identified by mass spectrometry in melanosome fractions from stage I to stage IV. In aortic samples, detected as an extracellular protein loosely bound to the matrix (PubMed:20551380); Tissue Specificity: Expressed in the aorta extrcellular space (at protein level).
VE:
1 * 100 µG
Artikel-Nr:
(PRSI5929)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
5929
Lokale Artikelnummer::
PRSI5929
Beschreibung:
ApoA4 Antibody: Apolipoprotein A4 (also known as ApoA-IV) is a plasma protein that is an O-linked glycoprotein after proteolytic processing. ApoA4 is a major constituent of HDL and it also can be found on the surface of newly synthesized chylomicrons. The physiological function of ApoA4 is not completely identified so far, but evidence from several in vitro studies indicate that this apolipoprotein is involved in several steps of the reverse cholesterol transport pathway, which transports cholesterol from peripheral cells back to the liver.
VE:
1 * 100 µG
Lieferant:
VWR Chemicals
Beschreibung:
Natriumsulfit 95,0-100,5%, gereinigt
Artikel-Nr:
(PRSI92-128)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
92-128
Lokale Artikelnummer::
PRSI92-128
Beschreibung:
Cytochrome C (CYCS) is a small heme protein that belongs to the cytochrome c family. It is found loosely associated with the inner membrane of the mitochondrion. Cytochrome C is a highly soluble protein that functions as a central component of the electron transport chain in mitochondria. CYCS transfers electrons between Complexes III (Coenzyme Q - Cyt C reductase) and IV (Cyt C oxidase). CYCS plays a role in apoptosis. Suppression of the anti-apoptotic members or activation of the pro-apoptotic members of the Bcl-2 family leads to altered mitochondrial membrane permeability resulting in release of cytochrome c into the cytosol. Binding of Cytochrome C to Apaf-1 triggers the activation of caspase-9, which then accelerates apoptosis by activating other caspases.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI91-346)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
91-346
Lokale Artikelnummer::
PRSI91-346
Beschreibung:
MMP3 is a member of the matrix metalloproteinase (MMP) family whose members are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, tissue remodeling, and disease processes including arthritis and metastasis. The MMP-3 enzyme degrades collagen types II, III, IV, IX, and X, proteoglycans, fibronectin, laminin, and elastin. In addition, MMP-3 can also activate other MMPs such as MMP-1, MMP-7, and MMP-9, rendering MMP-3 crucial in connective tissue remodeling.[3] The enzyme is thought to be involved in wound repair, progression of atherosclerosis, and tumor initiation.
VE:
1 * 50 µG
Artikel-Nr:
(BSBTPB9283)
Lieferant:
BosterBio
Hersteller-Artikelnummer::
PB9283
Lokale Artikelnummer::
BSBTPB9283
Beschreibung:
Polyclonal antibody for MT1 MMP/MMP14 detection. Host: Rabbit.Size: 100μg/vial. Tested applications: WB. Reactive species: Human. MT1 MMP/MMP14 information: Molecular Weight: 65894 MW; Subcellular Localization: Membrane ; Single-pass type I membrane protein . Melanosome. Cytoplasm. Identified by mass spectrometry in melanosome fractions from stage I to stage IV. Forms a complex with BST2 and localizes to the cytoplasm; Tissue Specificity: Expressed in stromal cells of colon, breast, and head and neck. Expressed in lung tumors.
VE:
1 * 100 µG
Artikel-Nr:
(PRSI34-110)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
34-110
Lokale Artikelnummer::
PRSI34-110
Beschreibung:
Fibronectin is a soluble dimeric glycoprotein of 440 kDa, which is present in cells, extracellular matrix, and blood. This mAb reacts with the cellular as well as plasma form of fibronectin. Reportedly, after iv administration, this mAb localizes to tumor vessels where it binds to the underlying basement. Epitope recognized by this antibody is not accessible in normal tissues to the circulating mAb indicating that it can be used to specifically target tumor vessels in vivo.
VE:
1 * 100 µG
New Product
Artikel-Nr:
(PRSI27-588)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
27-588
Lokale Artikelnummer::
PRSI27-588
Beschreibung:
SIRT7 is a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. SIRT7 is included in class IV of the sirtuin family.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI27-068)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
27-068
Lokale Artikelnummer::
PRSI27-068
Beschreibung:
COX18 is required for the insertion of integral membrane proteins into the mitochondrial inner membrane. COX18 is essential for the activity and assembly of cytochrome c oxidase. COX18 plays a central role in the translocation and export of the C-terminal part of the COX2 protein into the mitochondrial intermembrane space.COX18 encodes a cytochrome c oxidase (COX)-assembly protein. The S. cerevisiae Cox18 protein catalyzes the insertion of the Cox2 (MTCO2; MIM 516040) C-terminal tail into the mitochondrial inner membrane, an intermediate step in the assembly of complex IV of the mitochondrial respiratory chain (Sacconi et al., 2005 [PubMed 16212937]).
VE:
1 * 50 µG
Artikel-Nr:
(PRSI96-121)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
96-121
Lokale Artikelnummer::
PRSI96-121
Beschreibung:
CD36 (Cluster of Differentiation 36) is also known as platelet membrane glycoprotein IV (GPIV), fatty acid translocase (FAT), thrombospondin receptor, collagen receptor, and scavenger receptor class B, member 3 (SRB3), is a member of the class B scavenger receptor family of cell surface proteins. The human CD36 gene encodes a single chain 472 amino acid residue protein containing both an N- and a C-terminal cytoplasmic tail and an extracellular loop.CD36 is found on platelets, erythrocytes, monocytes, differentiated adipocytes, mammary epithelial cells, spleen cells and some skin microdermal endothelial cells. CD36 is a multiligand pattern recognition receptor that interacts with a large number of structurally dissimilar ligands, including long chain fatty acid (LCFA), advanced glycation end products (AGE), thrombospondin-1, oxidized low-density lipoproteins (oxLDLs), high density lipoprotein (HDL), phosphatidylserine, apoptotic cells, beta-amyloid fibrils (fAβ), collagens I and IV, and Plasmodium falciparum infected erythrocytes. CD36 is required for the anti-angiogenic effects of thrombospondin1 In the corneal neovascularisation assay. On binding a ligand the protein and ligand are internalized. This internalisation is independent of macropinocytosis and occurs by an actin dependent mechanism requiring the activation Src-family kinases, JNK and Rho-family GTPases. CD36 ligands have also been shown to promote sterile inflammation through assembly of a Toll-like receptor 4 and 6 heterodimer.
VE:
1 * 100 µG
Artikel-Nr:
(PRSI91-239)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
91-239
Lokale Artikelnummer::
PRSI91-239
Beschreibung:
Protein SCO1 Homolog, Mitochondrial (SCO1) is a member of the SCO1/2 family. SCO1 has a homodimer structure. SCO1 is located in mitochondrion and is highly expressed in muscle, heart, and brain. It is characterized by high rates of Oxidative Phosphorylation (OxPhos). SCO1 is thought to play a important role in cellular copper homeostasis, mitochondrial redox signaling and insertion of copper into the active site of COX. The defects of SCO1 can result in Mitochondrial Complex IV Deficiency (MT-C4D). A disorder of the mitochondrial respiratory chain has heterogeneous clinical manifestations, ranging from isolated myopathy to severe multisystem disease affecting several tissues and organs.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI29-568)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
29-568
Lokale Artikelnummer::
PRSI29-568
Beschreibung:
Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. They show extensive diversity in tissue distribution and in their subcellular localization. CA IV is a glycosylphosphatidyl-inositol-anchored membrane isozyme expressed on the luminal surfaces of pulmonary (and certain other) capillaries and of proximal renal tubules. Its exact function is not known, however, it may have a role in inherited renal abnormalities of bicarbonate transport.Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. They show extensive diversity in tissue distribution and in their subcellular localization. CA IV is a glycosylphosphatidyl-inositol-anchored membrane isozyme expressed on the luminal surfaces of pulmonary (and certain other) capillaries and of proximal renal tubules. Its exact function is not known, however, it may have a role in inherited renal abnormalities of bicarbonate transport.
VE:
1 * 100 µG
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