6-(4-Chlorophenoxy)pyridin-3-amine
Artikel-Nr:
(BOSSBS-13642R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13642R-CY3
Lokale Artikelnummer::
BOSSBS-13642R-CY3
Beschreibung:
Many growth factors function by binding receptors with intrinsic tyrosine kinase activity (1,2). Signaling by such receptors involves a series of intermediates characterized by SH2 domains that bind tyrosine phosphorylated receptors by a direct interaction between the SH2 domain and the phosphotyrosine-containing receptor sequences (3,4). GRB7, a SH2 domain protein, has a single SH2 domain at its C-terminal, a central region with similarity to Ras GAP and a proline-rich N-terminus (5,6). GRB7 maps to the region on mouse chromosome 11 containing the Neu gene (6). This region of mouse chromosome 11 is syntenic to an area of human chromosome 17q that is frequently amplified in breast cancer (6,7). Moreover, GRB7 is amplified and over-expressed in breast cancer and is found in a complex with Neu gp185 (6).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-13642R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13642R-CY5
Lokale Artikelnummer::
BOSSBS-13642R-CY5
Beschreibung:
Many growth factors function by binding receptors with intrinsic tyrosine kinase activity (1,2). Signaling by such receptors involves a series of intermediates characterized by SH2 domains that bind tyrosine phosphorylated receptors by a direct interaction between the SH2 domain and the phosphotyrosine-containing receptor sequences (3,4). GRB7, a SH2 domain protein, has a single SH2 domain at its C-terminal, a central region with similarity to Ras GAP and a proline-rich N-terminus (5,6). GRB7 maps to the region on mouse chromosome 11 containing the Neu gene (6). This region of mouse chromosome 11 is syntenic to an area of human chromosome 17q that is frequently amplified in breast cancer (6,7). Moreover, GRB7 is amplified and over-expressed in breast cancer and is found in a complex with Neu gp185 (6).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-8204R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-8204R
Lokale Artikelnummer::
BOSSBS-8204R
Beschreibung:
NEEP21, also known as Brain neuron cytoplasmic protein 1, NSG1 (neuron-specific proteins family member 1), P21 or D4S234E, is a single pass type II membrane protein belonging to the NSG family. It is highly expressed during neuronal maturation but its expression is downregulated in adult tissues. NEEP21 predominantly localizes to Rab 4-positive early endosomes in the somatodendritic neuronal compartment and is essential for proper receptor sorting and recycling in neurons. It associates with GRIP1 and GluR-2 and mediates the surface expression of GluR-2. When this interaction is interrupted, GluR-2 accumulates in early endosomes and leads to changes in evoked synaptic current properties. In addition, NEEP21 forms a complex with the SNARE protein, Syntaxin 13 (also known as Syntaxin 12), and participates in the recycling of transferrin receptors (TFRs) and NTR2 (neurotensin receptor 2).
VE:
1 * 100 µl
Lieferant:
BEHR
Beschreibung:
SG 12/B, Einsatzgestell für 12× SR 2 im SMA 12 oder SMA 12/HT
Lieferant:
Liebherr
Beschreibung:
Hochvolumige Gefrierschränke mit Umluftkühlung. Außenseite aus weißem Stahl und Innenseite aus Edelstahl. Die intuitiven Benutzeroberflächen bieten nützliche erweiterte Multifunktionalität, z. B. einen Wartungstimer, und die LED-Innenbeleuchtung sorgt für gute Sichtbarkeit des Inhalts dieser Großgeräte. Erweiterte Anschlussmöglichkeiten für unterschiedliche Anforderungen zur vereinfachten Datenspeicherung, Temperaturkontrolle und Alarmsignale.
Artikel-Nr:
(BOSSBS-8466R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-8466R
Lokale Artikelnummer::
BOSSBS-8466R
Beschreibung:
F-box proteins are critical components of the SCF (Skp1-CUL-1-F-box protein) type E3 ubiquitin ligase complex and are involved in substrate recognition and recruitment for ubiquitination. They are members of a larger family of proteins that are involved in the regulation of a wide variety of cellular processes (including the cell cycle, immune responses, signaling cascades and developmental events) through the targeting of proteins, such as cyclins, cyclin-dependent kinase inhibitors, I˚B-å and ∫-catenin, for proteasomal degradation. FBL12 (F-box and leucine-rich repeat protein 12), also designated FBXL12, is a 326 amino acid protein that contains one F-box domain, five LRR (leucine-rich) repeats and exists as two alternatively spliced isoforms. FBL12 interacts with both Skp1 and CUL-1, and is encoded by a gene that maps to human chromosome 19p13.2.
VE:
1 * 100 µl
Artikel-Nr:
(1220540.)
Lieferant:
USP
Hersteller-Artikelnummer::
1220540
Lokale Artikelnummer::
USPH1220540
Beschreibung:
USP Reference Standards are specified for use in conducting official USP–NF tests and assays. To confirm accuracy and reproducibility, USP Reference Standards are rigorously tested and evaluated by multiple independent laboratories including USP, commercial, regulatory, and academic labs. USP also provide publicly available, official documentary standards for pharmaceutical ingredients in the USP–NF that link directly with our primary reference standards.
VE:
1 * 25 mg
Artikel-Nr:
(1013556.)
Lieferant:
USP
Hersteller-Artikelnummer::
1013556
Lokale Artikelnummer::
USPH1013556
Beschreibung:
USP Reference Standards are specified for use in conducting official USP–NF tests and assays. To confirm accuracy and reproducibility, USP Reference Standards are rigorously tested and evaluated by multiple independent laboratories including USP, commercial, regulatory, and academic labs. USP also provide publicly available, official documentary standards for pharmaceutical ingredients in the USP–NF that link directly with our primary reference standards.
VE:
1 * 15 mg
Artikel-Nr:
(84864.600)
Lieferant:
VWR Chemicals
Lokale Artikelnummer::
VWRC84864.600
Beschreibung:
Entspricht der Menge, die benötigt wird, um 1 l einer 0,1 M Lösung herzustellen.
VE:
1 * 170 mL
Lieferant:
Alfa Aesar
Beschreibung:
Alizarin-Komplexon, (max. 10% H₂O)
Artikel-Nr:
(705-0118)
Lieferant:
Hach
Hersteller-Artikelnummer::
23032
Lokale Artikelnummer::
HACH23032
Beschreibung:
Kaliumhydroxid 12 mol/l (12 N) in wässriger Lösung
VE:
1 * 100 mL
Lieferant:
SIGMA ALDRICH MICROSCOPY
Beschreibung:
Malachitgrün-Oxalat, Sigma-Aldrich®
Artikel-Nr:
(BOSSBS-9584R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9584R-HRP
Lokale Artikelnummer::
BOSSBS-9584R-HRP
Beschreibung:
Membrane receptor signaling by various ligands, including interferons and growth hormones such as EGF, induces activation of JAK kinases which then leads to tyrosine phosphorylation of the various Stat transcription factors. Stat1 and Stat2 are induced by IFN-å and form a heterodimer which is part of the ISGF3 transcription factor complex. Although early reports indicate Stat3 activation by EGF and IL-6, it has been shown that Stat3∫ appears to be activated by both while Stat3å is activated by EGF, but not by IL-6. Highest expression of Stat4 is seen in testis and myeloid cells. IL-12 has been identified as an activator of Stat4. Stat5 has been shown to be activated by Prolactin and by IL-3. Stat6 is involved in IL-4 activated signaling pathways.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9584R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9584R-A555
Lokale Artikelnummer::
BOSSBS-9584R-A555
Beschreibung:
Membrane receptor signaling by various ligands, including interferons and growth hormones such as EGF, induces activation of JAK kinases which then leads to tyrosine phosphorylation of the various Stat transcription factors. Stat1 and Stat2 are induced by IFN-å and form a heterodimer which is part of the ISGF3 transcription factor complex. Although early reports indicate Stat3 activation by EGF and IL-6, it has been shown that Stat3∫ appears to be activated by both while Stat3å is activated by EGF, but not by IL-6. Highest expression of Stat4 is seen in testis and myeloid cells. IL-12 has been identified as an activator of Stat4. Stat5 has been shown to be activated by Prolactin and by IL-3. Stat6 is involved in IL-4 activated signaling pathways.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-13642R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13642R-A488
Lokale Artikelnummer::
BOSSBS-13642R-A488
Beschreibung:
Many growth factors function by binding receptors with intrinsic tyrosine kinase activity (1,2). Signaling by such receptors involves a series of intermediates characterized by SH2 domains that bind tyrosine phosphorylated receptors by a direct interaction between the SH2 domain and the phosphotyrosine-containing receptor sequences (3,4). GRB7, a SH2 domain protein, has a single SH2 domain at its C-terminal, a central region with similarity to Ras GAP and a proline-rich N-terminus (5,6). GRB7 maps to the region on mouse chromosome 11 containing the Neu gene (6). This region of mouse chromosome 11 is syntenic to an area of human chromosome 17q that is frequently amplified in breast cancer (6,7). Moreover, GRB7 is amplified and over-expressed in breast cancer and is found in a complex with Neu gp185 (6).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-13642R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13642R-A680
Lokale Artikelnummer::
BOSSBS-13642R-A680
Beschreibung:
Many growth factors function by binding receptors with intrinsic tyrosine kinase activity (1,2). Signaling by such receptors involves a series of intermediates characterized by SH2 domains that bind tyrosine phosphorylated receptors by a direct interaction between the SH2 domain and the phosphotyrosine-containing receptor sequences (3,4). GRB7, a SH2 domain protein, has a single SH2 domain at its C-terminal, a central region with similarity to Ras GAP and a proline-rich N-terminus (5,6). GRB7 maps to the region on mouse chromosome 11 containing the Neu gene (6). This region of mouse chromosome 11 is syntenic to an area of human chromosome 17q that is frequently amplified in breast cancer (6,7). Moreover, GRB7 is amplified and over-expressed in breast cancer and is found in a complex with Neu gp185 (6).
VE:
1 * 100 µl
Preis auf Anfrage
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
![]()
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
![]()
Dieses Produkt kann nur an eine Lieferadresse versandt werden die über die entsprechende Lizenzen verfügt. Für weitere Hilfe bitte kontaktieren Sie Ihr VWR Vertriebszentrum.
-Additional Documentation May be needed to purchase this item. A VWR representative will contact you if needed.
Dieses Produkt wurde von Ihrer Organisation gesperrt. Bitte kontaktieren Sie Ihren Einkauf für weitere Informationen.
Dieses Produkt ist Ersatz für den von Ihnen gewünschten Artikel.
Dieses Produkt ist nicht mehr verfügbar. Bitte kontaktieren Sie den VWR Kundenservice.
|
|||||||||