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1-Methylcyclopropanamine+hydrochloride
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1-Methylcyclopropanamine+hydrochloride
Lieferant:
VWR Collection
Beschreibung:
Diese Nitril-Reinraumhandschuhe aus weichem Nitril werden aus carboxyliertem Acrylnitril-Butadien hergestellt und bieten zuverlässigen und komfortablen Handschutz bei anspruchsvollen Reinraumanwendungen.
Artikel-Nr:
(ABEB31047/45)
Lieferant:
ABEBA
Hersteller-Artikelnummer::
31047/45
Lokale Artikelnummer::
ABEB31047/45
Beschreibung:
ESD-Schuh mit Obermaterial aus Glattleder und einer leichten PU-Laufsohle (kraftstoffbeständig).
VE:
1 * 1 PAAR
Artikel-Nr:
(BOSSBS-0738R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0738R-A488
Lokale Artikelnummer::
BOSSBS-0738R-A488
Beschreibung:
Apoptotic regulator capable of exerting proapoptotic and anti-apoptotic activities and plays crucial roles in apoptosis, cell proliferation, and cell cycle control. Its anti-apoptotic activity is mediated through the inhibition of CASP3, CASP7 and CASP9, as well as by its E3 ubiquitin-protein ligase activity. As it is a weak caspase inhibitor, its anti-apoptotic activity is thought to be due to its ability to ubiquitinate DIABLO/SMAC targeting it for degradation thereby promoting cell survival. May contribute to caspase inhibition, by blocking the ability of DIABLO/SMAC to disrupt XIAP/BIRC4-caspase interactions. Protects against apoptosis induced by TNF or by chemical agents such as adriamycin, etoposide or staurosporine. Suppression of apoptosis is mediated by activation of MAPK8/JNK1, and possibly also of MAPK9/JNK2. This activation depends on TAB1 and NR2C2/TAK1. In vitro, inhibits CASP3 and proteolytic activation of pro-CASP9. Isoform 1 blocks staurosporine-induced apoptosis. Isoform 2 blocks etoposide-induced apoptosis. Isoform 2 protects against natural killer (NK) cell killing whereas isoform 1 augments killing.
VE:
1 * 100 µl
Lieferant:
BURKLE
Beschreibung:
These are light- and high-performance pump to transfer small quantities of watery media up to 300 mPas from canisters, barrels and narrow necked containers from 32 mm opening diameter. Laboratory pumps, with splash water protected motor 230 V/200 W (IP 44), with 1,5 m PVC-hose, PP nozzle, 2 hose clips, discharge spout, wall bracket.
Lieferant:
APOLLO SCIENTIFIC
Beschreibung:
Fmoc-Lys(ME,Boc)-OH
Artikel-Nr:
(BOSSBS-1865R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1865R-A750
Lokale Artikelnummer::
BOSSBS-1865R-A750
Beschreibung:
Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins, such as BCL2, SYT11, CCNE1, GPR37, RHOT1/MIRO1, MFN1, MFN2, STUB1, a 22 kDa O-linked glycosylated isoform of SNCAIP, SEPT5, TOMM2, USP3, ZNF746 and AIMP2. Mediates monoubiquitination as well as 'Lys-48'-linked and 'Lys-63'-linked polyubiquitination of substrates depending on the context. Participates in the removal and/or detoxification of abnormally folded or damaged protein by mediating 'Lys-63'-linked polyubiquitination of misfolded proteins such as PARK7: 'Lys-63'-linked polyubiquitinated misfolded proteins are then recognised by HDAC6, leading to their recruitment to aggresomes, followed by degradation. Mediates 'Lys-63'-linked polyubiquitination of SNCAIP, possibly playing a role in Lewy-body formation. Mediates monoubiquitination of BCL2, thereby acting as a positive regulator of autophagy. Promotes the autophagic degradation of dysfunctional depolarized mitochondria (mitophagy) by the ubiquitination of mitochondrial proteins such as TOMM2, RHOT1/MIRO1 and USP3 (PubMed:24896179). Mediates 'Lys-48'-linked polyubiquitination of ZNF746, followed by degradation of ZNF746 by the proteasome; possibly playing a role in the regulation of neuron death. Limits the production of reactive oxygen species (ROS). Regulates cyclin-E during neuronal apoptosis. In collaboration with CHPF isoform 2, may enhance cell viability and protect cells from oxidative stress. Independently of its ubiquitin ligase activity, protects from apoptosis by the transcriptional repression of p53/TP53. May protect neurons against alpha synuclein toxicity, proteasomal dysfunction, GPR37 accumulation, and kainate-induced excitotoxicity. May play a role in controlling neurotransmitter trafficking at the presynaptic terminal and in calcium-dependent exocytosis. May represent a tumor suppressor gene.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-1865R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1865R-A350
Lokale Artikelnummer::
BOSSBS-1865R-A350
Beschreibung:
Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins, such as BCL2, SYT11, CCNE1, GPR37, RHOT1/MIRO1, MFN1, MFN2, STUB1, a 22 kDa O-linked glycosylated isoform of SNCAIP, SEPT5, TOMM2, USP3, ZNF746 and AIMP2. Mediates monoubiquitination as well as 'Lys-48'-linked and 'Lys-63'-linked polyubiquitination of substrates depending on the context. Participates in the removal and/or detoxification of abnormally folded or damaged protein by mediating 'Lys-63'-linked polyubiquitination of misfolded proteins such as PARK7: 'Lys-63'-linked polyubiquitinated misfolded proteins are then recognized by HDAC6, leading to their recruitment to aggresomes, followed by degradation. Mediates 'Lys-63'-linked polyubiquitination of SNCAIP, possibly playing a role in Lewy-body formation. Mediates monoubiquitination of BCL2, thereby acting as a positive regulator of autophagy. Promotes the autophagic degradation of dysfunctional depolarized mitochondria (mitophagy) by the ubiquitination of mitochondrial proteins such as TOMM2, RHOT1/MIRO1 and USP3 (PubMed:24896179). Mediates 'Lys-48'-linked polyubiquitination of ZNF746, followed by degradation of ZNF746 by the proteasome; possibly playing a role in the regulation of neuron death. Limits the production of reactive oxygen species (ROS). Regulates cyclin-E during neuronal apoptosis. In collaboration with CHPF isoform 2, may enhance cell viability and protect cells from oxidative stress. Independently of its ubiquitin ligase activity, protects from apoptosis by the transcriptional repression of p53/TP53. May protect neurons against alpha synuclein toxicity, proteasomal dysfunction, GPR37 accumulation, and kainate-induced excitotoxicity. May play a role in controlling neurotransmitter trafficking at the presynaptic terminal and in calcium-dependent exocytosis. May represent a tumor suppressor gene.
VE:
1 * 100 µl
Lieferant:
ELMA SCHMIDBAUER
Beschreibung:
Powerful and individual - the versatile Elmasonic Select series for ultrasonic cleaning are equipped with 37 kHz ultrasonic frequency, 5 ultrasonic modes, the ability to save up to 4 cleaning programmes, a heating and tank volumes from 3 to 90 litres (model Select 60 and larger have a drain).
Artikel-Nr:
(111-2572)
Lieferant:
3M
Hersteller-Artikelnummer::
SF201SGAF-BLU
Lokale Artikelnummer::
MMMASF201SGAF-BLU
Beschreibung:
Das Sicherheitsglas SecureFit™ 200 ist leicht und verfügt über die 3M™ Pressure Diffusion Temple-Technologie. Sie verfügt über klare, kratzfeste und beschlagfreie Gläser sowie ein umlaufendes Design, das sicher und komfortabel ist.
VE:
1 * 1 ST
Lieferant:
HUBEI ORIENT INTL TRADING
Beschreibung:
Pleated mob cap for use in hygiene environments.
Lieferant:
3M
Beschreibung:
Die Gebläseeinheit Versaflo™ Turbo TR-600 ist ein am Gürtel befestigtes Luftreinigungsgerät. In Kombination mit einem der durch 3M zugelassenen Kopfteile bildet es ein Gebläse-Atemschutzsystem gegen Partikel, unangenehme Gerüche (wo zutreffend) sowie Gase und Dämpfe.
Artikel-Nr:
(BOSSBS-0738R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0738R-CY3
Lokale Artikelnummer::
BOSSBS-0738R-CY3
Beschreibung:
Apoptotic regulator capable of exerting proapoptotic and anti-apoptotic activities and plays crucial roles in apoptosis, cell proliferation, and cell cycle control. Its anti-apoptotic activity is mediated through the inhibition of CASP3, CASP7 and CASP9, as well as by its E3 ubiquitin-protein ligase activity. As it is a weak caspase inhibitor, its anti-apoptotic activity is thought to be due to its ability to ubiquitinate DIABLO/SMAC targeting it for degradation thereby promoting cell survival. May contribute to caspase inhibition, by blocking the ability of DIABLO/SMAC to disrupt XIAP/BIRC4-caspase interactions. Protects against apoptosis induced by TNF or by chemical agents such as adriamycin, etoposide or staurosporine. Suppression of apoptosis is mediated by activation of MAPK8/JNK1, and possibly also of MAPK9/JNK2. This activation depends on TAB1 and NR2C2/TAK1. In vitro, inhibits CASP3 and proteolytic activation of pro-CASP9. Isoform 1 blocks staurosporine-induced apoptosis. Isoform 2 blocks etoposide-induced apoptosis. Isoform 2 protects against natural killer (NK) cell killing whereas isoform 1 augments killing.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-0738R-CY5.5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0738R-CY5.5
Lokale Artikelnummer::
BOSSBS-0738R-CY5.5
Beschreibung:
Apoptotic regulator capable of exerting proapoptotic and anti-apoptotic activities and plays crucial roles in apoptosis, cell proliferation, and cell cycle control. Its anti-apoptotic activity is mediated through the inhibition of CASP3, CASP7 and CASP9, as well as by its E3 ubiquitin-protein ligase activity. As it is a weak caspase inhibitor, its anti-apoptotic activity is thought to be due to its ability to ubiquitinate DIABLO/SMAC targeting it for degradation thereby promoting cell survival. May contribute to caspase inhibition, by blocking the ability of DIABLO/SMAC to disrupt XIAP/BIRC4-caspase interactions. Protects against apoptosis induced by TNF or by chemical agents such as adriamycin, etoposide or staurosporine. Suppression of apoptosis is mediated by activation of MAPK8/JNK1, and possibly also of MAPK9/JNK2. This activation depends on TAB1 and NR2C2/TAK1. In vitro, inhibits CASP3 and proteolytic activation of pro-CASP9. Isoform 1 blocks staurosporine-induced apoptosis. Isoform 2 blocks etoposide-induced apoptosis. Isoform 2 protects against natural killer (NK) cell killing whereas isoform 1 augments killing.
VE:
1 * 100 µl
Lieferant:
3M
Beschreibung:
Diese Hygiene-Kits enthalten Ersatzdichtungen und Ohrenschützer, die mit wenigen Handgriffen ausgetauscht werden können. Zur Verwendung mit dem Gehörschutz der 3M™ Peltor™ X-Serie.
Artikel-Nr:
(APOSPC0504-1G)
Lieferant:
APOLLO SCIENTIFIC
Hersteller-Artikelnummer::
PC0504-1G
Lokale Artikelnummer::
APOSPC0504-1G
Beschreibung:
Fmoc-3,4,5-trifluoro-D-phenylalanine
VE:
1 * 1 g
Artikel-Nr:
(APOSOR8030-1G)
Lieferant:
APOLLO SCIENTIFIC
Hersteller-Artikelnummer::
OR8030-1G
Lokale Artikelnummer::
APOSOR8030-1G
Beschreibung:
(R)-1-Boc-piperidine-2-carboxylic acid
VE:
1 * 1 g
Preis auf Anfrage
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Dieses Produkt kann nur an eine Lieferadresse versandt werden die über die entsprechende Lizenzen verfügt. Für weitere Hilfe bitte kontaktieren Sie Ihr VWR Vertriebszentrum.
-Additional Documentation May be needed to purchase this item. A VWR representative will contact you if needed.
Dieses Produkt wurde von Ihrer Organisation gesperrt. Bitte kontaktieren Sie Ihren Einkauf für weitere Informationen.
Dieses Produkt ist Ersatz für den von Ihnen gewünschten Artikel.
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