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2-(2-Fluorophenyl)-3-oxobutanenitrile
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2-(2-Fluorophenyl)-3-oxobutanenitrile
Artikel-Nr:
(BOSSBS-6815R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6815R-A750
Lokale Artikelnummer::
BOSSBS-6815R-A750
Beschreibung:
LRRC15 may contribute to regulation of cell-matrix adhesion interactions with respect to astrocyte recruitment around senile plaques in Alzheimer's disease brain. LRRC15 is induced by EWS-WT1(+KTS) in the tumor DSRCT and may play a role in cellular invasion.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3215R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3215R-A680
Lokale Artikelnummer::
BOSSBS-3215R-A680
Beschreibung:
HDAC6 is a member of the class II mammalian histone deacetylases. Human HDAC6 is composed of 1215 amino acid residues. It possesses two separate putative catalytic domains. Both catalytic domains are fully functional HDACs and contribute independently to the overall activity of HDAC6 protein. A very potent NES is present at the amino-terminus of HDAC6, which was found to play an important role in regulating the shuttling of HDAC6 protein between cytoplasm and nucleus. The shuttling process may be a critical regulatory mechanism of HDAC6 function. The expression of HDAC6 is tightly linked to the state of cell differentiation. HDAC6 may participate in coordinating expression of a group of genes involved in the remodelling of chromatin during cell differentiation.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-15549R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-15549R-CY7
Lokale Artikelnummer::
BOSSBS-15549R-CY7
Beschreibung:
IFI27.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-6294R-CY5.5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6294R-CY5.5
Lokale Artikelnummer::
BOSSBS-6294R-CY5.5
Beschreibung:
This gene encodes a serum protein found in association with the major histocompatibility complex (MHC) class I heavy chain on the surface of nearly all nucleated cells. The protein has a predominantly beta-pleated sheet structure that can form amyloid fibrils in some pathological conditions. A mutation in this gene has been shown to result in hypercatabolic hypoproteinemia.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5770R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5770R-CY3
Lokale Artikelnummer::
BOSSBS-5770R-CY3
Beschreibung:
FGF17 belongs to the heparin-binding growth factors family. It may be a signaling molecule in the induction and patterning of the embryonic brain and is preferentially expressed in the embryonic brain. There are two named isoforms.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-6096R-CY5.5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6096R-CY5.5
Lokale Artikelnummer::
BOSSBS-6096R-CY5.5
Beschreibung:
The protein encoded by this gene is a multi-membrane spanning protein containing a RING-H2 finger. This protein is located in the endoplasmic reticulum, and has been shown to possess ubiquitin ligase activity. This gene was found to be interrupted by a t(3:8) translocation in a family with hereditary renal and non-medulary thyroid cancer. Studies of the Drosophila counterpart suggested that this protein may interact with tumor suppressor protein VHL, as well as with COPS5/JAB1, a protein responsible for the degradation of tumor suppressor CDKN1B/P27KIP.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-15330R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-15330R-A350
Lokale Artikelnummer::
BOSSBS-15330R-A350
Beschreibung:
C9orf5 (chromosome 9 open reading frame 5), also known as CG2, is a 911 amino acid multi-pass membrane protein that is widely expressed and exists as four alternatively spliced isoforms. The gene encoding C9orf5 maps to human chromosome 9, which consists of about 145 million bases, represents 4% of the human genome and encodes nearly 900 genes. Considered to play a role in gender determination, deletion of the distal portion of 9p can lead to development of male to female sex reversal, the phenotype of a female with a male X,Y genotype. Hereditary hemorrhagic telangiectasia, which is characterised by harmful vascular defects, is associated with the chromosome 9 gene encoding endoglin protein, ENG. Familial dysautonomia is also associated with chromosome 9 though through the gene IKBKAP. Notably, chromosome 9 encompasses the largest interferon family gene cluster. Chromosome 9 is partnered with chromosome 22 in the translocation leading to the aberrant production of BCR-ABL fusion protein often found in leukemias.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-15406R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-15406R-HRP
Lokale Artikelnummer::
BOSSBS-15406R-HRP
Beschreibung:
Tuberous sclerosis complex (TSC) is an autosomal dominant genetic disorder characterised by mental retardation and the widespread development of distinctive tumors termed hamartomas. Two different genetic loci have been linked to TSC; one of these loci, the tuberous sclerosis-2 gene (TSC2), encodes a protein called tuberin and the other loci, tuberous sclerosis-1 gene (TSC1), encodes a protein called hamartin. Tuberin and hamartin interact with each other forming a cystoplasmic complex. Hamartin interacts with the ezrin-radixin-moesin (ERM) family of actin-binding proteins and inhibition of hamartin activity results in loss of cell adhesion. Hamartin is present in most adult tissues with strong expression in brain, heart, and kidney.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9223R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9223R-A680
Lokale Artikelnummer::
BOSSBS-9223R-A680
Beschreibung:
Has E2-dependent E3 ubiquitin-protein ligase activity. Ubiquitinates MAGED1 antigen leading to its subsequent degradation by proteasome (By similarity). May be involved in protein sorting.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-15379R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-15379R-FITC
Lokale Artikelnummer::
BOSSBS-15379R-FITC
Beschreibung:
This gene encodes a member of the membrane-associated guanylate kinase (MAGUK) protein family, with an N-terminal PDZ domain, a central src homology 3 region (SH3), and a C-terminal guanylate kinase-like (GUK) domain. The protein is localised to the outer limiting membrane in the retina, and is thought to function in photoreceptor polarity and the organisation of specialised intercellular junctions. Alternatively spliced transcript variants have been described, but their biological validity has not been determined.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-15402R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-15402R-CY7
Lokale Artikelnummer::
BOSSBS-15402R-CY7
Beschreibung:
HABP4.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-4260R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-4260R-A555
Lokale Artikelnummer::
BOSSBS-4260R-A555
Beschreibung:
ATP-dependent 3'-5' DNA helicase, component of the core-TFIIH basal transcription factor, involved in nucleotide excision repair (NER) of DNA and, when complexed to CAK, in RNA transcription by RNA polymerase II. Acts by opening DNA either around the RNA transcription start site or the DNA damage.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3831R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3831R-A555
Lokale Artikelnummer::
BOSSBS-3831R-A555
Beschreibung:
Catalyzes the initial step in triglyceride hydrolysis in adipocyte and non-adipocyte lipid droplets. Also has acylglycerol transacylase activity. May act coordinately with LIPE/HLS within the lipolytic cascade. Regulates adiposome size and may be involved in the degradation of adiposomes. May play an important role in energy homeostasis. May play a role in the response of the organism to starvation, enhancing hydrolysis of triglycerides and providing free fatty acids to other tissues to be oxidized in situations of energy depletion.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-10210R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-10210R-CY5
Lokale Artikelnummer::
BOSSBS-10210R-CY5
Beschreibung:
The Trk family of nerve growth factor receptors includes Trk A(also referfed to as Trk A gp140),Trk B and Trk C. The prototype member of this gene family, Trk A, encodes a 140 kDa cell surface receptor , gp140, the expression of which is restricted in vivo to neurons of the sensory spinal and cranial gangliaof neurocrest origin. Nerve growth factor (NGF) stimulates tyrosine phosphorylation of Trk gp 140 in neural cell lines and in embryonic dorsal root ganglia. By comparison, BDNF and to a lesser extent, NT-3, but not NGF, can induce tyrosine phophorylayion of Trk B gp 145. The third member of the Trk receptor family, Trk C incodes a 140 kDa protein, Trk C gp140, that is preferentially expressed in brain tissue and primarily functions as a receptor for NT-3.An additional component of the Trk receptor complex, NGFR p175, binds to neurotrophic factors with low affinity but is required for efficient signaling. NGFR p175 accelerates Trk activation and may recruit downstream dffector molecules to the ligand-bound receptor complex.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-4196R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-4196R-A647
Lokale Artikelnummer::
BOSSBS-4196R-A647
Beschreibung:
Receptor for prostaglandin E2 (PGE2). The activity of this receptor is mediated by G(s) proteins that stimulate adenylate cyclase. The subsequent raise in intracellular cAMP is responsible for the relaxing effect of this receptor on smooth muscle.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5884R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5884R-A350
Lokale Artikelnummer::
BOSSBS-5884R-A350
Beschreibung:
Endothelial sialomucin, also called endomucin or mucin-like sialoglycoprotein, which interferes with the assembly of focal adhesion complexes and inhibits interaction between cells and the extracellular matrix.
VE:
1 * 100 µl
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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