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Reagenzien zur Entfernung von Farbstoffen
Artikel-Nr:
(BOSSBS-8210R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-8210R-A555
Lokale Artikelnummer::
BOSSBS-8210R-A555
Beschreibung:
Made up of nearly 146 million bases, chromosome 8 encodes about 800 genes. Translocation of portions of chromosome 8 with amplifications of the c-Myc gene are found in some leukemias and lymphomas, and typically associated with a poor prognosis. Portions of chromosome 8 have been linked to schizophrenia and bipolar disorder. Trisomy 8, also known as Warkany syndrome 2, most often results in early miscarriage but is occasionally seen in a mosaic form in surviving patients who suffer to a varying degree from a number of symptoms including retarded mental and motor development, and certain facial and developmental defects. WRN is a DNA helicase encoded by chromosome 8 and shown defective in those with the early aging disorder Werner syndrome. Chromosome 8 is also associated with Pfeiffer syndrome, congenital hypothyroidism and Waardenburg syndrome. The FAM91A1 gene product has been provisionally designated FAM91A1 pending further characterization.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-12518R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12518R-A350
Lokale Artikelnummer::
BOSSBS-12518R-A350
Beschreibung:
Eukaryotic translation initiation factor 2C (eIF2C) proteins (argonaute family) influence RNA interference (RNAi) as components of the RNA-inducible silencing complex (RISC) or microRNA (miRNA)-containing ribonucleoprotein particle (miRNP). Small RNAs, including small interfering RNAs (siRNAs) and miRNAs, can silence target genes through mechanisms that utilize RISC or miRNP particles. eIF2C1 (argonaute 1, AGO1, eIF2C, GERP95, Q99) and Dicer1 play a coordinated role in siRNA-mediated gene silencing. eIF2C2 (Slicer, argonaute 2, AGO2, Q10) is a RISC component that can concentrate in cytoplasmic processing bodies (P-bodies) and catalyze mRNA cleavage. Mammalian P-bodies contain mRNAs and have an association with miRNA-induced translational silencing and siRNA-induced mRNA degradation. Additional eIF2C proteins include eIF2C3 (argonaute 3, AGO3), eIF2C4 (argonaute 4, AGO4) and meIF2c5 (mouse argonaute 5).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-8411R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-8411R-A750
Lokale Artikelnummer::
BOSSBS-8411R-A750
Beschreibung:
Cysteine-rich secretory proteins (CRISPs) represent a family of evolutionarily conserved proteins that may play a role in the innate immune system and are transcriptionally regulated by androgens in several tissues. GAPR-1 (Golgi-associated plant pathogenesis-related protein 1), also known as GLIPR2, is a 154 amino acid lipid anchor protein belonging to the CRISP family. GAPR-1 also shares similarity with the pathogenesis-related protein (PR) superfamily, and may play an important role in the immune system. Existing as a homodimer, GAPR-1 is highly expressed in lung and peripheral leukocytes with minor expression in liver and kidney. Containing a conserved sperm-coating protein (SCP) domain, GAPR-1 binds to negatively charged lipids and may be involved in the differentiation of epithelial cells into mesenchymal cells. Increased expression of GAPR-1 in kidney may contribute to the development of fibrosis.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-15285R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-15285R-A750
Lokale Artikelnummer::
BOSSBS-15285R-A750
Beschreibung:
Made up of nearly 146 million bases, chromosome 8 encodes about 800 genes. Translocation of portions of chromosome 8 with amplifications of the c-Myc gene are found in some leukemias and lymphomas, and typically associated with a poor prognosis. Portions of chromosome 8 have been linked to schizophrenia and bipolar disorder. Trisomy 8, also known as Warkany syndrome 2, most often results in early miscarriage but is occasionally seen in a mosaic form in surviving patients who suffer to a varying degree from a number of symptoms including retarded mental and motor development, and certain facial and developmental defects. WRN is a DNA helicase encoded by chromosome 8 and shown defective in those with the early aging disorder Werner syndrome. Chromosome 8 is also associated with Pfeiffer syndrome, congenital hypothyroidism and Waardenburg syndrome. The C8orf31 gene product has been provisionally designated C8orf31 pending further characterisation.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-7533R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-7533R-A488
Lokale Artikelnummer::
BOSSBS-7533R-A488
Beschreibung:
Lipin 1 is a member of the Lipin family of nuclear proteins. This family contains three members: Lipin 1, Lipin 2 and Lipin 3, all of which contain a nuclear signal sequence, a highly conserved amino-terminal (NLIP) domain and a carboxy-terminal (CLIP) domain. LPIN1 (Lipin 1) is crucial for normal adipose tissue development and metabolism. LPIN1 selectively activates a subset of PGC1 alpha target pathways, including fatty acid oxidation and mitochondrial oxidative phosphorylation by inducing expression of the nuclear receptor PPARalpha. LPIN1 also inactivates the lipogenic program and suppresses circulating lipid levels. An abundance of LPIN1 promotes fat accumulation and insulin sensitivity, whereas a deficiency in LPIN1 may deter normal adipose tissue development, resulting in insulin resistance and lipodystrophy, a heterogeneous group of disorders characterized by loss of body fat, fatty liver, hypertriglyceridemia and insulin resistance.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-8578R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-8578R-A750
Lokale Artikelnummer::
BOSSBS-8578R-A750
Beschreibung:
GRAMD2 is a 354 amino acid single-pass membrane protein that contains one GRAM domain and is encoded by a gene that maps to human chromosome 15q23. Encoding more than 700 genes, chromosome 15 is made up of approximately 106 million base pairs and is about 3% of the human genome. Angelman and Prader-Willi syndromes are associated with loss of function or deletion of genes in the 15q11-q13 region. In the case of Angelman syndrome, this loss is due to inactivity of the maternal 15q11-q13 encoded UBE3A gene in the brain by either chromosomal deletion or mutation. In cases of Prader-Willi syndrome, there is a partial or complete deletion of this region from the paternal copy of chromosome 15. Tay-Sachs disease is a lethal disorder associated with mutations of the HEXA gene, which is encoded by chromosome 15. Marfan syndrome is associated with chromosome 15 through the FBN1 gene.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11428R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11428R-A350
Lokale Artikelnummer::
BOSSBS-11428R-A350
Beschreibung:
Neuropeptides are regulators of synaptic transmission and their effects are mediated by G-protein coupled receptors. NPS (Neuropeptide S) is a 20 amino acid peptide cleaved from a larger precursor that contains a hydrophobic signal peptide and proteolytic cleavage processing sites. The N-terminal residue of NPS is always a serine regardless of the species. NPS is predominantly found in the central nervous system and plays an important role regulating sleep/wake functions, locomotion, arousal/anxiety responses and food intake. NPS functions by binding and activating its receptor, NPSR, and increasing intracellular calcium levels thereby acting as an excitatory transmitter. In addition, NPS stimulates the hypothalamo-pituitary adrenal (HPA) axis via the release of corticotropin-releasing factor (CRF) and arginine vasopressin (AVP). NPS and its receptor NPSR may also play a role in asthma pathogenesis.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-8350R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-8350R-A647
Lokale Artikelnummer::
BOSSBS-8350R-A647
Beschreibung:
The ubiquitin (Ub) pathway involves three sequential enzymatic steps that facilitate the conjugation of Ub and Ub-like molecules to specific protein substrates. The first step requires the ATP-dependent activation of the Ub C-terminus and the assembly of multi-Ub chains by the Ub-activating enzyme known as the E1 component. The Ub chain is then conjugated to the Ub-conjugating enzyme (E2) to generate an intermediate Ub-E2 complex. The Ub-ligase (E3) then catalyzes the transfer of Ub from E2 to the appropriate protein substrate. UBE2E1 and UBE2L3, also designated UBCH6 and UBCH7 respectively in human, are E2 conjugating enzymes that interact with various proteins. Specifically, UBE2E1 interacts with the tumor suppressor protein TSSC5. UBE2L3 has been shown to mediate c-fos degradation, NF-kB maturation, human papilloma virus-mediated p53 and Myc protein degradation.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-12342R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12342R-A555
Lokale Artikelnummer::
BOSSBS-12342R-A555
Beschreibung:
Polycomb group (PcG) proteins are important for maintaining the transcriptionally repressed state of target genes and are thought to function via chromatin modification. PcG proteins assemble into multimeric protein complexes, which are involved in maintaining the transcriptional repressive state of genes over successive cell generations. PcG proteins are also required for normal maturation of myeloid progenitor cells. A putative PcG protein, L3MBTL3 (lethal(3)malignant brain tumor-like protein 3), also known as MBT-1 or KIAA1798, is a 780 amino acid protein containing three MBT repeats and one SAM (sterile alpha motif) domain. Localized to the nucleus, L3MBTL3 interacts with RING1B, another PcG protein that may be involved in the specification of anterior-posterior axis and cell proliferation in early development. L3MBTL3 exists as two isoforms produced by alternative splicing events.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-15085R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-15085R-A647
Lokale Artikelnummer::
BOSSBS-15085R-A647
Beschreibung:
C1QTNF9
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-12977R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12977R-A488
Lokale Artikelnummer::
BOSSBS-12977R-A488
Beschreibung:
AZI1
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9004R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9004R-A647
Lokale Artikelnummer::
BOSSBS-9004R-A647
Beschreibung:
SAMD3
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-12977R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12977R-A680
Lokale Artikelnummer::
BOSSBS-12977R-A680
Beschreibung:
AZI1
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9004R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9004R-A680
Lokale Artikelnummer::
BOSSBS-9004R-A680
Beschreibung:
SAMD3.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-15320R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-15320R-A647
Lokale Artikelnummer::
BOSSBS-15320R-A647
Beschreibung:
C9orf172.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-15164R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-15164R-A750
Lokale Artikelnummer::
BOSSBS-15164R-A750
Beschreibung:
C3IP1
VE:
1 * 100 µl
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Dieses Produkt kann nur an eine Lieferadresse versandt werden die über die entsprechende Lizenzen verfügt. Für weitere Hilfe bitte kontaktieren Sie Ihr VWR Vertriebszentrum.
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