2-Amino-5-bromo-4-methoxybenzoic+acid
Artikel-Nr:
(BOSSBS-12877R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12877R-A750
Lokale Artikelnummer::
BOSSBS-12877R-A750
Beschreibung:
Predominantly localised to the nucleolus, BOP1 (Block of proliferation 1 protein) is a 746 amino acid highly conserved non-ribosomal protein that is involved in ribosome biogenesis. Truncation of the amino terminus of BOP1 leads to cell growth arrest in the G1 phase and specific inhibition of 28S and 5.8S rRNA synthesis, as well as a deficit in the cytosolic 60S ribosomal subunit. This suggests that BOP1 is involved in the formation of mature rRNAs and in the biogenesis of the 60S ribosomal subunit. BOP1 physically interacts with pescadillo (a protein involved in cell proliferation) and enables efficient incorporation of pescadillo into the nucleolar preribosomal complexes, thereby affecting rRNA maturation and the cell cycle. The BOP1-pescadillo complex is also necessary for biogenesis of 60S ribosomal subunits. Deregulation of BOP1 may lead to colorectal tumourigenesis.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-12877R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12877R-A680
Lokale Artikelnummer::
BOSSBS-12877R-A680
Beschreibung:
Predominantly localised to the nucleolus, BOP1 (Block of proliferation 1 protein) is a 746 amino acid highly conserved non-ribosomal protein that is involved in ribosome biogenesis. Truncation of the amino terminus of BOP1 leads to cell growth arrest in the G1 phase and specific inhibition of 28S and 5.8S rRNA synthesis, as well as a deficit in the cytosolic 60S ribosomal subunit. This suggests that BOP1 is involved in the formation of mature rRNAs and in the biogenesis of the 60S ribosomal subunit. BOP1 physically interacts with pescadillo (a protein involved in cell proliferation) and enables efficient incorporation of pescadillo into the nucleolar preribosomal complexes, thereby affecting rRNA maturation and the cell cycle. The BOP1-pescadillo complex is also necessary for biogenesis of 60S ribosomal subunits. Deregulation of BOP1 may lead to colorectal tumourigenesis.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-12191R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12191R-A488
Lokale Artikelnummer::
BOSSBS-12191R-A488
Beschreibung:
DZIP3 is a 1,208 amino acid protein that localizes to the cytoplasm and contains one RING-type zinc finger. Expressed in a variety of tissues with highest expression in heart, skeletal muscle and kidney, DZIP3 functions as an E3 ubiquitin-protein ligase that accepts ubiquitin from an E2 ubiquitin-conjugating enzyme, thereby playing a role in signaling events throughout the cell. Multiple isoforms of DZIP3 exist due to alternative splicing events.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-0813R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0813R-A555
Lokale Artikelnummer::
BOSSBS-0813R-A555
Beschreibung:
Casein is the name for a family of related phosphoproteins. These proteins are commonly found in mammalian milk, making up 80% of the proteins in cow milk and between 20% and 45% of the proteins in human milk. Casein has a wide variety of uses, from being a major component of cheese, to use as a food additive, to a binder for safety matches. As a food source, casein supplies amino acids; carbohydrates; and two inorganic elements, calcium and phosphorus.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5467R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5467R-HRP
Lokale Artikelnummer::
BOSSBS-5467R-HRP
Beschreibung:
Gamma Catenin is a common junctional plaque protein. The membrane-associated plaques are architectural elements in an important strategic position to influence the arrangement and function of both the cytoskeleton and the cells within the tissue. The presence of gamma Catenin in both the desmosomes and in the intermediate junctions suggests that it plays a central role in the structure and function of submembranous plaques. It is a member of the catenin family since it contains a distinct repeating amino acid motif called the armadillo repeat.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5467R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5467R-A680
Lokale Artikelnummer::
BOSSBS-5467R-A680
Beschreibung:
Gamma Catenin is a common junctional plaque protein. The membrane-associated plaques are architectural elements in an important strategic position to influence the arrangement and function of both the cytoskeleton and the cells within the tissue. The presence of gamma Catenin in both the desmosomes and in the intermediate junctions suggests that it plays a central role in the structure and function of submembranous plaques. It is a member of the catenin family since it contains a distinct repeating amino acid motif called the armadillo repeat.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-12191R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12191R-A350
Lokale Artikelnummer::
BOSSBS-12191R-A350
Beschreibung:
DZIP3 is a 1,208 amino acid protein that localizes to the cytoplasm and contains one RING-type zinc finger. Expressed in a variety of tissues with highest expression in heart, skeletal muscle and kidney, DZIP3 functions as an E3 ubiquitin-protein ligase that accepts ubiquitin from an E2 ubiquitin-conjugating enzyme, thereby playing a role in signaling events throughout the cell. Multiple isoforms of DZIP3 exist due to alternative splicing events.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-12191R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12191R-A680
Lokale Artikelnummer::
BOSSBS-12191R-A680
Beschreibung:
DZIP3 is a 1208 amino acid protein that localizes to the cytoplasm and contains one RING-type zinc finger. Expressed in a variety of tissues with highest expression in heart, skeletal muscle and kidney, DZIP3 functions as an E3 ubiquitin-protein ligase that accepts ubiquitin from an E2 ubiquitin-conjugating enzyme, thereby playing a role in Signalling events throughout the cell. Multiple isoforms of DZIP3 exist due to alternative splicing events.
VE:
1 * 100 µl
Artikel-Nr:
(BTIU80026)
Lieferant:
Biotium
Hersteller-Artikelnummer::
80026
Lokale Artikelnummer::
BTIU80026
Beschreibung:
Lucifer Yellow CH lithium salt (LY CH lithium salt) is a widely used polar molecular tracer for studying neuronal morphology. The fluorescent molecule contains a carbohydrazide that allow the molecule to be aldehyde-fixable. The lithium salt form of Lucifer Yellow is in an aqueous solution format that is ready for microinjection.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-12388R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12388R-FITC
Lokale Artikelnummer::
BOSSBS-12388R-FITC
Beschreibung:
KIF7 is a 1,343 amino acid protein expressed in embryonic stem cells, melanotic melanoma and Jurkat T-cells. KIF7 is a member of the KIF27 subfamily of the kinesin-like protein family and contains one kinesin-motor domain. It is suggested that KIF7 may participate in the Hedgehog (Hh) signaling pathway by regulating the proteolysis and stability of GLI transcription factors. Hedgehog (Hh) signaling plays a critical role in embryonic development.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11174R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11174R-A488
Lokale Artikelnummer::
BOSSBS-11174R-A488
Beschreibung:
KY peptidase (Kyphoscoliosis peptidase) is a 561 amino acid cytoskeleton protease that interacts with several sarcomeric cytoskeletal proteins, including Filamin 2. KY peptidase probably plays a role in the maturation, function and stabilization of the neuromuscular junction. KY-null mouse mutants exhibit distinct irregular subceullular Filamin 2 localization, suggesting that KY peptidase deficiency may be the cause of several types of limb-girdle muscular dystrophies.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-12340R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12340R-A647
Lokale Artikelnummer::
BOSSBS-12340R-A647
Beschreibung:
Vanin-2 is a 520 amino acid GPI-anchor protein that belongs to the CN hydrolase family and BTD/VNN subfamily.Widely expressed with high expression in spleen and blood, vanin-2 is suggested to be involved in thymus homing of bone marrow cells, regulation of Integrin ∫2-mediated cell adhesion, and migration and motility of neutrophils. Vanin-2 exists as five alternatively spliced isoforms and is encoded by a gene mapping to human chromosome 6q23.2.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11174R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11174R-A750
Lokale Artikelnummer::
BOSSBS-11174R-A750
Beschreibung:
KY peptidase (Kyphoscoliosis peptidase) is a 561 amino acid cytoskeleton protease that interacts with several sarcomeric cytoskeletal proteins, including Filamin 2. KY peptidase probably plays a role in the maturation, function and stabilisation of the neuromuscular junction. KY-null mouse mutants exhibit distinct irregular subcellular Filamin 2 localisation, suggesting that KY peptidase deficiency may be the cause of several types of limb-girdle muscular dystrophies.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11174R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11174R-A350
Lokale Artikelnummer::
BOSSBS-11174R-A350
Beschreibung:
KY peptidase (Kyphoscoliosis peptidase) is a 561 amino acid cytoskeleton protease that interacts with several sarcomeric cytoskeletal proteins, including Filamin 2. KY peptidase probably plays a role in the maturation, function and stabilization of the neuromuscular junction. KY-null mouse mutants exhibit distinct irregular subceullular Filamin 2 localization, suggesting that KY peptidase deficiency may be the cause of several types of limb-girdle muscular dystrophies.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-1163R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1163R-A647
Lokale Artikelnummer::
BOSSBS-1163R-A647
Beschreibung:
Defensins form a family of microbicidal and cytotoxic peptides made by neutrophils. Members of the defensin family are highly similar in protein sequence. This gene encodes defensin, beta 1, an antimicrobial peptide implicated in the resistance of epithelial surfaces to microbial colonization. This gene maps in close proximity to defensin family member, defensin, alpha 1 and has been implicated in the pathogenesis of cystic fibrosis. The mature form of Beta defensin 1 is 36 amino acids.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9214R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9214R-CY5
Lokale Artikelnummer::
BOSSBS-9214R-CY5
Beschreibung:
Metastasis of a primary tumor to a distant site is determined through signaling cascades that break down interactions between the cell and extracellular matrix proteins. Among the proteins mediating metastasis are serine prote-ases, such as neutrophil elastase.SCCA is transcribed by two nearly identical genes (SCCA1 and SCCA2), and is mainly produced as SCCA1. The human SCCA1 gene encodes a 390 amino acid protein that was originally isolated from a metastatic cervical squamous cell carcinoma.
VE:
1 * 100 µl
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