Suche >
2-Amino-5-bromo-4-methoxybenzoic+acid
Drucken
Sie suchten nach:
188 301 results were found
2-Amino-5-bromo-4-methoxybenzoic+acid
Artikel-Nr:
(BOSSBS-5353R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5353R-CY3
Lokale Artikelnummer::
BOSSBS-5353R-CY3
Beschreibung:
FANCG, involved in Fanconi anemia, confers resistance to both hygromycin and mitomycin C. FANCG contains a 5-prime GC-rich untranslated region characteristic of housekeeping genes. The putative 622-amino acid protein has a leucine-zipper motif at its N-terminus. Fanconi anemia is an autosomal recessive disorder with diverse clinical symptoms, including developmental anomalies, bone marrow failure, and early occurrence of malignancies. A minimum of 8 FA genes have been identified.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-12252R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12252R
Lokale Artikelnummer::
BOSSBS-12252R
Beschreibung:
ZFP57 is a 452 amino acid protein that contains one KRAB domain and seven C2H2-type zinc fingers and is a member of the Krüppel C2H2-type zinc-finger protein family. Localized to the nucleus, ZFP57 functions as a transcriptional repressor that inhibits the expression of Schwann cell-specific proteins, thereby playing a role in the development of the peripheral nervous system. ZFP57 exists as two isoforms that are produced from alternative splicing events.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3148R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3148R-CY3
Lokale Artikelnummer::
BOSSBS-3148R-CY3
Beschreibung:
Glycogen synthase kinase 3 (GSK3) is a proline directed serine threonine kinase that was initially identified as a phosphorylating and inactivating glycogen synthase. GSK3 has been implicated in fundamental cell processes such as cell fate determination, metabolism, transcriptional control and oncogenesis. Two isoforms, alpha (GSK3A; OMIM 606784) and beta, show a high degree of amino acid homology within their catalytic domains. GSK3B is involved in energy metabolism, neuronal cell development and body pattern formation.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-15548R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-15548R-CY3
Lokale Artikelnummer::
BOSSBS-15548R-CY3
Beschreibung:
IFI16 is a member of the HIN-200 (hematopoietic interferon-inducible nuclear antigens with 200 amino acid repeats) family of cytokines. The encoded protein contains domains involved in DNA binding, transcriptional regulation, and protein-protein interactions. The protein localises to the nucleoplasm and nucleoli, and interacts with p53 and retinoblastoma-1. It modulates p53 function, and inhibits cell growth in the Ras/Raf signaling pathway. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11075R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11075R
Lokale Artikelnummer::
BOSSBS-11075R
Beschreibung:
CNTNAP3B is a 1,288 amino acid protein that is encoded by a gene which maps to human chromosome 9. Chromosome 9 contains 145 million base pairs and comprises 4% of the human genome, encoding nearly 900 genes. Hereditary hemorrhagic telangiectasia, which is characterized by harmful vascular defects, and Familial dysautonomia, are both associated with chromosome 9. Notably, chromosome 9 encompasses the largest interferon family gene cluster. Chromosome 9 is partnered with chromosome 22 in translocations that lead to the aberrant production of a BCR-ABL fusion protein often found in leukemias.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-13265R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13265R-CY3
Lokale Artikelnummer::
BOSSBS-13265R-CY3
Beschreibung:
GALE is a 348 amino acid protein that functions as the third enzyme in the Leloir pathway of galactose metabolism. A member of the sugar epimerase family, GALE exists as a homodimer, binds FAD as a cofactor and catalyzes the epimerization of UDP-N-acetylglucosamine to UDP-N-acetylgalactosamine and UDP-glucose to UDP-galactose. The gene encoding GALE maps to human chromosome 1p36.11 and mutations in this gene lead to the development of complex disorder known as epimerase-deficiency galactosemia (EDG) or galactosemia type 3, which is characterized by mental retardation, liver damage, cataracts and deafness.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-0234R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0234R
Lokale Artikelnummer::
BOSSBS-0234R
Beschreibung:
The placental-derived growth factor (PIGF) is a dimeric glycoprotein showing a high degree of sequence similarity to the vascular endothelial growth factor. Alternative splicing of the PIGF primary transcript gives rise to two forms, named PIGF-1 and PIGF-2, which differ only in the insertion of a highly basic 21-amino acid stretch at the carboxyl end. The presence of the PIGF mRNA in thyroid, placenta, lung, and goiter has indicated the tissues where this factor functions. However, the role of PIGF in vascular development has not yet been clearly established.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11691R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11691R
Lokale Artikelnummer::
BOSSBS-11691R
Beschreibung:
FLAD1 is a 587 amino acid protein where its N-terminus belongs to the moaB/mog family and its C-terminus belongs to the PAPS reductase family. Existing as five alternatively spliced isoforms, FLAD1 localizes to the cytoplasm and utilizes magnesium as a cofactor. FLAD1 is a key enzyme in the metabolic pathway that converts riboflavin into the redox cofactor flavin adenine dinucleotide (FAD). It is suggested that the molybdenum cofactor biosynthesis protein-like region of FLAD1 may not be functional.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-12493R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12493R-HRP
Lokale Artikelnummer::
BOSSBS-12493R-HRP
Beschreibung:
APOBEC2 is a 224 amino acid protein that belongs to the cytidine and deoxycytidylate deaminase family. Expressed exclusively in heart and skeletal muscle, APOBEC2 is thought to be a probable C (cytidine) to U (uridine) editing enzyme. However, unlike other members of the family, such as APOBEC1, which mediates the editing of apolipoprotein (apo) B mRNA, APOBEC2 does not display any detectable apoB mRNA editing activity. Also, APOBEC2 has been shown to have low, but definite, intrinsic cytidine deaminase activity.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-8339R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-8339R-HRP
Lokale Artikelnummer::
BOSSBS-8339R-HRP
Beschreibung:
The pantothenate kinase (PANK) family of proteins catalyzes the first step in coenzyme A (CoA) biosynthesis. Coenzyme A is an important coenzyme involved in the synthesis and oxidation of fatty acids, as well as the oxidation of pyruvate in the citric acid (Krebs) cycle. Pantothenate kinase 3 (PANK3) is a 370 amino acid member of the pantothenate kinase family that plays a role in the physiological regulation of the intracellular CoA concentration. Localized to the cytoplasm, PANK3 is regulated by feedback inhibition by CoA and its thioesters. PANK3 transfers a phosphate from ATP to pantothenate (Vitamin B5), resulting in formation of 4’-phosphopantothenate. Closely related to its family members, PANK1, PANK2 and PANK4, PANK3 is highly expressed in liver. Pantothenate kinase associated neurodegeneration (PKAN) results from mutations in the gene encoding PANK2, the only mitochondria targeted human PANK.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-15483R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-15483R-A488
Lokale Artikelnummer::
BOSSBS-15483R-A488
Beschreibung:
HIBADH is a 336 amino acid mitochondrial enzyme that catalyses the NAD+-dependent, reversible oxidisation of 3-Hydroxyisobutyrate to methylmalonate semialdehyde, an intermediate of valine catabolism. The enzyme functions as a homodimer between a pH of 7,0 and 10,0, with optimal activity between 8,8 and 9,0. It was previously hypothesised that defects in the gene encoding HIBADH may be the cause of 3-Hydroxyisobutyric aciduria, a rare disorder that is characterised by a variety of clinical manifestations such as neurodevelopmental problems and dysmorphic features. However, it was shown that HIBADH activity was equal in patients with 3-Hydroxyisobutyric aciduria as compared with controls.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-0932R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0932R-HRP
Lokale Artikelnummer::
BOSSBS-0932R-HRP
Beschreibung:
This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. Two transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq].
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9577R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9577R-A680
Lokale Artikelnummer::
BOSSBS-9577R-A680
Beschreibung:
TSPEAR, also known as C21orf9, is a 669 amino acid secreted protein. Expressed as two isoforms produced by alternative splicing, TSPEAR contains one Thrombospondin N-terminal domain and seven EAR (epilepsy-associated repeat) domains. EAR domains are found in several proteins, including TSPEAR, encoded by genes that map within chromosome regions associated with seizure disorders. It is thought that the EAR domain plays a role in the pathogenesis of epilepsy by either binding to an unknown epileptic ligand or interfering with axon synaptogenesis.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9662R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9662R-FITC
Lokale Artikelnummer::
BOSSBS-9662R-FITC
Beschreibung:
EFR3A is a plasma membrane protein that contains 821 amino acids and belongs to the EFR3 family. EFR3A is alternatively spliced creating three isoforms and is encoded by a gene that maps to human chromosome 8. Human chromosome 8 consists of nearly 146 million base pairs, encodes over 800 genes and is associated with a variety of diseases and malignancies. Schizophrenia, bipolar disorder, Trisomy 8, Pfeiffer syndrome, congenital hypothyroidism, Waardenburg syndrome and some leukemias and lymphomas are thought to occur as a result of defects in specific genes that map to chromosome 8.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-15483R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-15483R-A750
Lokale Artikelnummer::
BOSSBS-15483R-A750
Beschreibung:
HIBADH is a 336 amino acid mitochondrial enzyme that catalyses the NAD+-dependent, reversible oxidisation of 3-Hydroxyisobutyrate to methylmalonate semialdehyde, an intermediate of valine catabolism. The enzyme functions as a homodimer between a pH of 7,0 and 10,0, with optimal activity between 8,8 and 9,0. It was previously hypothesised that defects in the gene encoding HIBADH may be the cause of 3-Hydroxyisobutyric aciduria, a rare disorder that is characterised by a variety of clinical manifestations such as neurodevelopmental problems and dysmorphic features. However, it was shown that HIBADH activity was equal in patients with 3-Hydroxyisobutyric aciduria as compared with controls.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-8249R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-8249R-A488
Lokale Artikelnummer::
BOSSBS-8249R-A488
Beschreibung:
DCAKD belongs to the coaE family. It contains one DPCK (dephospho CoA kinase) domain. There are two isoforms.Coenzyme A (CoA) is an essential cofactor used in numerous biochemical pathways. It plays a critical role in the synthesis and oxidation of fatty acids and is vital to the citric acid cycle. The biosynthesis pathway of CoA from pantothenic acid (also known as vitamin B5) is essential and universal in prokaryotes and eukaryotes. In humans, the final steps of the biosynthesis pathway are carried out by the bifunctional enzyme COASY. The sequence of these enzymes are highly conserved between different bacterial species. The phosphopantetheine adenylyltransferase and decoenzyme A kinase activities of COASY are evolutionarily conserved activities. DCAKD (deCoA kinase domain containing protein) is a 231 amino acid protein that consists of a deCoA kinase domain and an ATP nucleotide binding motif. Localizing to mitochondria and the cytosol, DCAKD belongs to the coaE family which suggests that it may play a role in the biosynthesis of CoA.
VE:
1 * 100 µl
Preis auf Anfrage
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Dieses Produkt kann nur an eine Lieferadresse versandt werden die über die entsprechende Lizenzen verfügt. Für weitere Hilfe bitte kontaktieren Sie Ihr VWR Vertriebszentrum.
-Additional Documentation May be needed to purchase this item. A VWR representative will contact you if needed.
Dieses Produkt wurde von Ihrer Organisation gesperrt. Bitte kontaktieren Sie Ihren Einkauf für weitere Informationen.
Dieses Produkt ist Ersatz für den von Ihnen gewünschten Artikel.
Dieses Produkt ist nicht mehr verfügbar. Bitte kontaktieren Sie den VWR Kundenservice.
|
|||||||||
Listenansicht
