2\\\'-Methoxy-6\\\'-methylbiphenyl-3-carbonsäure
Artikel-Nr:
(BOSSBS-12948R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12948R-A555
Lokale Artikelnummer::
BOSSBS-12948R-A555
Beschreibung:
CRTAC1 is a 661 amino acid secreted protein. CRTAC1 is O-glycosylated and contains one EGF-like domain and four FG-GAP repeats. Up-regulated in mesenchymal stem cells undergoing chondrogenic differentiation and also by growth factor BMP-4, CRTAC1 is found in the interterritorial matrix of articular deep zone cartilage. CRTAC1 is expressed as three isoforms produced by alternative splicing events. All isoforms are expressed in bone, cartilage and lung, while isoforms 1 and 2 are expressed in the brain. The gene that encodes CRTAC1 maps to human chromosome 10, which contains over 800 genes and 135 million nucleotides, making up nearly 4.5% of the human genome.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-12351R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12351R
Lokale Artikelnummer::
BOSSBS-12351R
Beschreibung:
STRA6 is a 667 amino acid, multi-pass cell membrane protein. Stra6 functions as a cell-surface receptor for the complex retinol-retinol binding protein (RBP/RBP4). Ultimately increasing cellular retinol uptake from the retinol-RBP complex, Stra6 removes retinol from RBP/RPB4 and transports it across the plasma membrane, where it is metabolized. Stra6 is broadly expressed, with 4 named isoforms that exist as a result of alternative splicing events. Mutations in the gene encoding Stra6 cause Matthew-Wood Syndrome, also known as Spear Syndrome. This syndrome is characterized by anophtalmia, mild facial dysmorphism and malformations of the heart, lung and diaphragm. The Stra6 gene maps to chromosome 15q24.1.
VE:
1 * 100 µl
Lieferant:
COMBI-BLOCKS
Beschreibung:
2-Amino-5-brom-3-methylbenzoesäure
Artikel-Nr:
(23257.183)
Lieferant:
VWR Chemicals
Lokale Artikelnummer::
VWRC23257.183
Beschreibung:
L(+)-Cystein Hydrochlorid Monohydrat 98,5-101,0% für die Biochemie
VE:
1 * 100 g
Lieferant:
FLUOROCHEM
Beschreibung:
6-Amino-2-naphthoesäure
Artikel-Nr:
(MOLEM86924892)
Lieferant:
Molekula
Hersteller-Artikelnummer::
M86924892
Lokale Artikelnummer::
MOLEM86924892
Beschreibung:
5-Amino-2-chlorbenzoesäure
VE:
1 * 100 g
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Artikel-Nr:
(BOSSBS-15078R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-15078R-CY5
Lokale Artikelnummer::
BOSSBS-15078R-CY5
Beschreibung:
C1orf85, also known as Lysosomal protein NCU-G1, is a 406 amino acid single-pass membrane protein that is highly glycosylated on its amino-terminal end. Transcription of the gene encoding C1orf85 is activated by TFEB, a transcription factor that specifically recognizes and binds E-box sequences. There are two isoforms of C1orf85 that are produced as a result of alternative splicing events. The C1orf85 maps to human chromosome 1, the largest human chromosome spanning about 260 million base pairs and making up 8% of the human genome. There are about 3,000 genes on chromosome 1, and considering the great number of genes there are also a large number of diseases associated with chromosome 1. Notably, the rare aging disease Hutchinson-Gilford progeria is associated with the LMNA gene which encodes lamin A. When defective, the LMNA gene product can build up in the nucleus and cause characteristic nuclear blebs. The mechanism of rapidly enhanced aging is unclear and is a topic of continuing exploration. The MUTYH gene is located on chromosome 1 and is partially responsible for familial adenomatous polyposis. Stickler syndrome, Parkinsons, Gaucher disease and Usher syndrome are also associated with chromosome 1.
VE:
1 * 100 µl
Artikel-Nr:
(SIAL651621-1G)
Lieferant:
Sigma-Aldrich
Hersteller-Artikelnummer::
651621-1G
Lokale Artikelnummer::
SIAL651621-1G
Beschreibung:
4-Amino-3-nitrophenylboronsäure, Sigma-Aldrich®
VE:
1 * 1 g
Artikel-Nr:
(BOSSBS-9454R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9454R-HRP
Lokale Artikelnummer::
BOSSBS-9454R-HRP
Beschreibung:
Acyl-coenzyme A synthetases (ACSs) are a large family of related enzymes known to catalyze the fundamental initial reaction in fatty acid metabolism. The ACS family is roughly characterized based on fatty acid chain length preference amongst different members. The nomenclature in the ACS family reflects this relationship and includes short-chain ACS (ACSS), medium-chain ACS (ACSM), long-chain ACS (ACSL) and very long-chain ACS (ACSVL). ACSVL family members are capable of activating both long (LCFAs) and very long-chain fatty acids (VLCFAs). There are six members of the human ACSVL subfamily, which have been described as solute carrier family 27A (SLC27A) gene products. They represent a group of evolutionarily conserved fatty acid transport proteins (FATPs) recognized for their role in facilitating translocation of long-chain fatty acids across the plasma membrane. The family nomenclature has recently been unified with their respective acyl-CoA synthetase family designations: ACSVL1 (FATP2), ACSVL2 (FATP6), ACSVL3 (FATP3), ACSVL4 (FATP1), ACSVL5 (FATP4) and ACSVL6 (FATP5). ACSVLs have unique expression patterns and are found in major organs of fatty acid metabolism, such as adipose tissue, liver, heart and kidney. ACSVL2 is a 619 amino acid multi-pass membrane protein. Encoded by a gene that maps to human chromosome 5q23.3, ACSVL2 may function as the predominant fatty acid protein transporter in heart.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9454R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9454R-A555
Lokale Artikelnummer::
BOSSBS-9454R-A555
Beschreibung:
Acyl-coenzyme A synthetases (ACSs) are a large family of related enzymes known to catalyze the fundamental initial reaction in fatty acid metabolism. The ACS family is roughly characterized based on fatty acid chain length preference amongst different members. The nomenclature in the ACS family reflects this relationship and includes short-chain ACS (ACSS), medium-chain ACS (ACSM), long-chain ACS (ACSL) and very long-chain ACS (ACSVL). ACSVL family members are capable of activating both long (LCFAs) and very long-chain fatty acids (VLCFAs). There are six members of the human ACSVL subfamily, which have been described as solute carrier family 27A (SLC27A) gene products. They represent a group of evolutionarily conserved fatty acid transport proteins (FATPs) recognized for their role in facilitating translocation of long-chain fatty acids across the plasma membrane. The family nomenclature has recently been unified with their respective acyl-CoA synthetase family designations: ACSVL1 (FATP2), ACSVL2 (FATP6), ACSVL3 (FATP3), ACSVL4 (FATP1), ACSVL5 (FATP4) and ACSVL6 (FATP5). ACSVLs have unique expression patterns and are found in major organs of fatty acid metabolism, such as adipose tissue, liver, heart and kidney. ACSVL2 is a 619 amino acid multi-pass membrane protein. Encoded by a gene that maps to human chromosome 5q23.3, ACSVL2 may function as the predominant fatty acid protein transporter in heart.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11568R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11568R-A680
Lokale Artikelnummer::
BOSSBS-11568R-A680
Beschreibung:
HS1BP3 is a 392 amino acid protein that contains one PX (phox homology) domain, a leucine zipper, immunoreceptor tyrosine-based inhibitory motif-like motifs and multiple proline-rich regions. Expressed primarily in brain, HS1BP3 is encoded by a gene mapping to human chromosome 2p24.1. The gene encoding HS1BP3 is frequently mutated in familial essential tremor, a disorder characterised by kinetic tremor the the hands, voice or head, though there is no correlation to Parkinson disease. HS1BP3 interacts with HAX-1 SH3 domain, and may also play a role in the regulation of catecholamine and serotonin metabolism. Acting as a regulator of IL-2 Signalling, HS1BP3 is likely involved in lymphocyte activation.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-12345R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12345R-A680
Lokale Artikelnummer::
BOSSBS-12345R-A680
Beschreibung:
HEM1 is a 1127 amino acid single-pass membrane protein that localizes to the cytoplasmic side of the cell membrane. One of several members of the highly conserved HEM family of tissue-specific transmembrane proteins, HEM1 is expressed in cells of hematopoietic origin where it is thought to play an important role in oogenesis. The gene encoding HEM1 maps to human chromosome 12, which encodes over 1100 genes and comprises approximately 4.5% of the human genome. Chromosome 12 is associated with a variety of diseases and afflictions, including hypochondrogenesis, achondrogenesis, Kniest dysplasia, Noonan syndrome and Trisomy 12p, which causes facial developmental defects and seizure disorders.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11751R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11751R-A750
Lokale Artikelnummer::
BOSSBS-11751R-A750
Beschreibung:
Polyglutamine(Q) tract binding protein-1 (PQBP-1) is a transcription repressor that associates with polyglutamine tract-containing transcription regulators and causative genes for neurodegenerative disorders. Hepta- and di-amino acid repeat sequences rich in polar residues are essential for PQBP-1 to interact with polyglutamine tract-containing proteins (i.e. huntingtin, androgen receptor and Brain-2). PQBP-1 contains a WWP/WW domain that binds proline-rich motifs and a C2 domain that can influence Ca2+-dependent phospholipid Signalling. PQBP-1 localizes to the nucleus and is present in neurons throughout the brain, with abundant levels in hippocampus, cerebellar cortex and olfactory bulb. The human PQBP-1 gene maps to chromosome Xp11.23.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11581R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11581R-A680
Lokale Artikelnummer::
BOSSBS-11581R-A680
Beschreibung:
PDZ-GEF1 is a 1499 amino acid cell membrane protein that functions as a guanine nucleotide exchange factor for Rap 1A, Rap 1B and Rap 2B GTPases. Expressed at highest levels in brain, PDZ-GEF1 is found at low levels in placenta, heart, lung and kidney, and undergoes post-translational phosphorylation following DNA damage. PDZ-GEF1 interacts with MAGI-2 and contains one Ras-GEF domain, a Ras-associating domain, one PDZ (DHR) domain, a single N-terminal Ras-GEF domain and a cyclic nucleotide-binding domain. The gene encoding PDZ-GEF1 maps to human chromosome 4q32.1.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-8460R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-8460R-FITC
Lokale Artikelnummer::
BOSSBS-8460R-FITC
Beschreibung:
FNDC1, also known as MEL4B3, Ags8, Expressed in synovial lining protein and Activation-associated cDNA protein, is a 1888 amino acid secreted protein that contains five fibronectin type-III domains. FNDC1 is moderately expressed in skeletal muscle, pancreas, heart, kidney, spinal cord, ovary and lung. Expression of FNDC1 is induced in response to hypoxia in ventricular cardiomyocytes. Since FNDC1 interacts with G∫ and G©, it is likely that FNDC1 is an activator for G-protein signaling. Though normally absent in healthy skin, FNDC1 expression is induced by TGF-beta signaling in skin tumors and psoriasis. There are two isoforms of FNDC1 that are produced as a result of alternative splicing events.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-12639R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12639R-A680
Lokale Artikelnummer::
BOSSBS-12639R-A680
Beschreibung:
BSPRY is a 402 amino acid protein that localizes to both the membrane and the cytoplasm and contains one B box-type zinc finger and one B30.2/SPRY domain. Existing as two alternatively spliced isoforms, BSPRY interacts with TRPV5 and TRPV6 and is thought to regulate the transport of calcium across the epithelium, probably by inhibiting the activity of TRPV proteins. The gene encoding BSPRY maps to human chromosome 9, which houses over 900 genes and comprises nearly 4% of the human genome. Hereditary hemorrhagic telangiectasia, which is characterised by harmful vascular defects, and Familial dysautonomia, are both associated with chromosome 9. Notably, chromosome 9 encompasses the largest interferon family gene cluster.
VE:
1 * 100 µl
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