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2-Brom-4,5-dimethoxybenzoes\\\\\\\\u00E4ure
Artikel-Nr:
(BOSSBS-11945R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11945R-HRP
Lokale Artikelnummer::
BOSSBS-11945R-HRP
Beschreibung:
Encoding over 1,100 genes within 132 million bases, chromosome 12 makes up about 4.5% of the human genome. A number of skeletal deformities are linked to chromosome 12 including hypochondrogenesis, achondrogenesis and Kniest dysplasia. Noonan syndrome, which includes heart and facial developmental defects among the primary symptoms, is caused by a mutant form of PTPN11 gene product, SH-PTP2. Chromosome 12 is also home to a homeobox gene cluster which encodes crucial transcription factors for morphogenesis, and the natural killer complex gene cluster encoding C-type lectin proteins which mediate the NK cell response to MHC I interaction. Trisomy 12p leads to facial development defects, seizure disorders and a host of other symptoms varying in severity depending on the extent of mosaicism and is most severe in cases of complete trisomy. The C12orf52 gene product has been provisionally designated C12orf52 pending further characterization.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9948R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9948R-A680
Lokale Artikelnummer::
BOSSBS-9948R-A680
Beschreibung:
Encoding over 1100 genes within 132 million bases, chromosome 12 makes up about 4.5% of the human genome. A number of skeletal deformities are linked to chromosome 12 including hypochondrogenesis, achondrogenesis and Kniest dysplasia. Noonan syndrome, which includes heart and facial developmental defects among the primary symptoms, is caused by a mutant form of PTPN11 gene product, SH-PTP2. Chromosome 12 is also home to a homeobox gene cluster which encodes crucial transcription factors for morphogenesis, and the natural killer complex gene cluster encoding C-type lectin proteins which mediate the NK cell response to MHC I interaction. Trisomy 12p leads to facial development defects, seizure disorders and a host of other symptoms varying in severity depending on the extent of mosaicism and is most severe in cases of complete trisomy. The C12orf42 gene product has been provisionally designated C12orf42 pending further characterisation.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-10056R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-10056R-CY5
Lokale Artikelnummer::
BOSSBS-10056R-CY5
Beschreibung:
KNDC1 is a 1,749 amino acid protein that contains two KIND domains and an N-terminal Ras-GEF domain. Expressed in the cerebral cortex, KNDC1 is a likely guanine nucleotide exchange factor (GEF). Existing as six alternatively spliced isoforms, the gene encoding KNDC1 maps to human chromosome 10q26.3 and mouse chromosome 7 F4. Spanning nearly 135 million base pairs, chromosome 10 makes up approximately 4.5% of total DNA in cells and encodes nearly 1,200 genes. Several protein-coding genes, including those that encode for chemokines, cadherins, excision repair proteins, early growth response factors (Egrs) and fibroblast growth receptors (FGFRs), are located on chromosome 10. Defects in some of the genes that map to chromosome 10 are associated with Charcot-Marie Tooth disease, Jackson-Weiss syndrome, Usher syndrome, nonsyndromatic deafness, Wolman’s syndrome, Cowden syndrome, multiple endocrine neoplasia type 2 and porphyria.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-8229R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-8229R-A350
Lokale Artikelnummer::
BOSSBS-8229R-A350
Beschreibung:
Encoding over 1,100 genes within 132 million bases, chromosome 12 makes up about 4.5% of the human genome. A number of skeletal deformities are linked to chromosome 12 including hypochondrogenesis, achondrogenesis and Kniest dysplasia. Noonan syndrome, which includes heart and facial developmental defects among the primary symptoms, is caused by a mutant form of PTPN11 gene product, SH-PTP2. Chromosome 12 is also home to a homeobox gene cluster which encodes crucial transcription factors for morphogenesis, and the natural killer complex gene cluster encoding C-type lectin proteins which mediate the NK cell response to MHC I interaction. Trisomy 12p leads to facial development defects, seizure disorders and a host of other symptoms varying in severity depending on the extent of mosaicism and is most severe in cases of complete trisomy. The FAM101A gene product has been provisionally designated FAM101A pending further characterization.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9946R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9946R-A750
Lokale Artikelnummer::
BOSSBS-9946R-A750
Beschreibung:
Encoding over 1100 genes within 132 million bases, chromosome 12 makes up about 4.5% of the human genome. A number of skeletal deformities are linked to chromosome 12 including hypochondrogenesis, achondrogenesis and Kniest dysplasia. Noonan syndrome, which includes heart and facial developmental defects among the primary symptoms, is caused by a mutant form of PTPN11 gene product, SH-PTP2. Chromosome 12 is also home to a homeobox gene cluster which encodes crucial transcription factors for morphogenesis, and the natural killer complex gene cluster encoding C-type lectin proteins which mediate the NK cell response to MHC I interaction. Trisomy 12p leads to facial development defects, seizure disorders and a host of other symptoms varying in severity depending on the extent of mosaicism and is most severe in cases of complete trisomy. The C12orf29 gene product has been provisionally designated C12orf29 pending further characterisation.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9953R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9953R-A680
Lokale Artikelnummer::
BOSSBS-9953R-A680
Beschreibung:
Encoding over 1100 genes within 132 million bases, chromosome 12 makes up about 4.5% of the human genome. A number of skeletal deformities are linked to chromosome 12 including hypochondrogenesis, achondrogenesis and Kniest dysplasia. Noonan syndrome, which includes heart and facial developmental defects among the primary symptoms, is caused by a mutant form of PTPN11 gene product, SH-PTP2. Chromosome 12 is also home to a homeobox gene cluster which encodes crucial transcription factors for morphogenesis, and the natural killer complex gene cluster encoding C-type lectin proteins which mediate the NK cell response to MHC I interaction. Trisomy 12p leads to facial development defects, seizure disorders and a host of other symptoms varying in severity depending on the extent of mosaicism and is most severe in cases of complete trisomy. The C12orf61 gene product has been provisionally designated C12orf61 pending further characterisation.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-12883R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12883R-CY5
Lokale Artikelnummer::
BOSSBS-12883R-CY5
Beschreibung:
The breast cancer susceptibility gene (BRCA1) localizes to chromosome 17q. Mutations within this gene account for approximately 45% of families with high incidence of breast cancer and at least 80% of families with increased incidence of both early-onset breast cancer and ovarian cancer. A second breast cancer susceptibility gene, BRCA2, located on chromosome 13q12-13, also confers a high incidence of breast cancer, but unlike BRCA1, BRCA2 does not confer a substantially elevated risk of ovarian cancer. The BRCA2-Associated Factor 35 (BRAF35) protein forms a complex with BRCA2, which associates with condensed chromatin during histone H3 phosphorylation. BRAF35 expression levels are highest in proliferating tissues and parallel BRCA2 expression patterns. The structure of BRAF35 includes a kinesin-like coiled coil domain and a nonspecific DNA binding HMG domain. The chromatin localization of BRAF35 and antibody microinjection studies indicate a role for the BRAF35/BRCA2 complex in cell cycle regulation.
VE:
1 * 100 µl
Artikel-Nr:
(USBI146205)
Lieferant:
US Biological
Hersteller-Artikelnummer::
146205
Lokale Artikelnummer::
USBI146205
Beschreibung:
Anti-BRE Rabbit Polyclonal Antibody
VE:
1 * 100 µG
Lieferant:
MP Biomedicals
Beschreibung:
Bromocresol purple sodium salt is typically used as a pH indicator (5,2 - 6,8 : yellow to blue-purple). Used in spectrophotometric determination of serum-albumin.
Artikel-Nr:
(USBI031834)
Lieferant:
US Biological
Hersteller-Artikelnummer::
031834
Lokale Artikelnummer::
USBI031834
Beschreibung:
Anti-AMFR Rabbit Polyclonal Antibody
VE:
1 * 200 µl
Artikel-Nr:
(ORIGTA326551)
Lieferant:
OriGene
Hersteller-Artikelnummer::
TA326551
Lokale Artikelnummer::
ORIGTA326551
Beschreibung:
Anti-Kcna5 Mouse Monoclonal Antibody [clone: S7-45]
VE:
1 * 100 µG
Lieferant:
SELECTA
Beschreibung:
Gabled stainless steel lid with thermometer positioning hole, Edelstahl, Für: 45 L bath
Artikel-Nr:
(BOSSBS-12883R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12883R-A488
Lokale Artikelnummer::
BOSSBS-12883R-A488
Beschreibung:
The breast cancer susceptibility gene (BRCA1) localizes to chromosome 17q. Mutations within this gene account for approximately 45% of families with high incidence of breast cancer and at least 80% of families with increased incidence of both early-onset breast cancer and ovarian cancer. A second breast cancer susceptibility gene, BRCA2, located on chromosome 13q12-13, also confers a high incidence of breast cancer, but unlike BRCA1, BRCA2 does not confer a substantially elevated risk of ovarian cancer. The BRCA2-Associated Factor 35 (BRAF35) protein forms a complex with BRCA2, which associates with condensed chromatin during histone H3 phosphorylation. BRAF35 expression levels are highest in proliferating tissues and parallel BRCA2 expression patterns. The structure of BRAF35 includes a kinesin-like coiled coil domain and a nonspecific DNA binding HMG domain. The chromatin localization of BRAF35 and antibody microinjection studies indicate a role for the BRAF35/BRCA2 complex in cell cycle regulation.
VE:
1 * 100 µl
Artikel-Nr:
(THSARB24-15-45)
Lieferant:
THERMO SAVANT
Hersteller-Artikelnummer::
RB24-15-45
Lokale Artikelnummer::
THSARB24-15-45
Beschreibung:
Rotor block, PP, for (24) 1 dram vial, 15×45 mm
VE:
1 * 1 ST
Lieferant:
Biotium
Beschreibung:
Recognizes a 53 kDa protein, which is identified as p53 suppressor gene product. It reacts with the mutant as well as the wild form of p53. Its epitope maps within the N-terminus (aa 37-45) of p53. Monoclonal antibody PAb1801 does not block the binding of DO-7 MAb to p53 in an ELISA test. p53 is a tumor suppressor gene expressed in a wide variety of tissue types and is involved in regulating cell growth, replication, and apoptosis. It binds to MDM2, SV40 T antigen and human papilloma virus E6 protein. Positive nuclear staining with p53 antibody has been reported to be a negative prognostic factor in breast carcinoma, lung carcinoma, colorectal, and urothelial carcinoma. Anti-p53 positivity has also been used to differentiate uterine serous carcinoma from endometrioid carcinoma as well as to detect intratubular germ cell neoplasia. Mutations involving p53 are found in a wide variety of malignant tumors, including breast, ovarian, bladder, colon, lung, and melanoma.
Artikel-Nr:
(BOSSBS-11698R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11698R-CY5
Lokale Artikelnummer::
BOSSBS-11698R-CY5
Beschreibung:
Huntingtin yeast partner E is a 458 amino acid single-pass membrane protein. HYPE is thought to interact with Huntingtin, a protein which induces neurodegeneration when mutated. HYPE also contains two tetratricopeptide repeats (TPR), which may be involved in protein-protein interaction. The gene that encodes HYPE is located on chromosome 12, which encodes over 1,100 genes within 132 million bases and makes up about 4.5% of the human genome. A number of skeletal deformities are linked to chromosome 12 including hypochondrogenesis, achondrogenesis and Kniest dysplasia. Chromosome 12 is also home to a homeobox gene cluster which encodes crucial transcription factors for morphogenesis, and the natural killer complex gene cluster encoding C-type lectin proteins which mediate the NK cell response to MHC I interaction. Trisomy 12p leads to facial development defects, seizure disorders and a host of other symptoms varying in severity depending on the extent of mosaicism and is most severe in cases of complete trisomy.
VE:
1 * 100 µl
Preis auf Anfrage
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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