2-Amino-5-bromo-4-methoxybenzoic+acid
Artikel-Nr:
(BSENR-1381-100)
Lieferant:
Biosensis
Hersteller-Artikelnummer::
R-1381-100
Lokale Artikelnummer::
BSENR-1381-100
Beschreibung:
Ubiquitinous metalloproteinase that is involved in diverse functions such as remodeling of the vasculature, angiogenesis, tissue repair, tumor invasion, inflammation, and atherosclerotic plaque rupture. As well as degrading extracellular matrix proteins, can also act on several nonmatrix proteins such as big endothelial 1 and beta-type CGRP promoting vasoconstriction. Also cleaves KISS at a Gly-|-Leu bond. Appears to have a role in myocardial cell death pathways. Contributes to myocardial oxidative stress by regulating the activity of GSK3beta. Cleaves GSK3beta in vitro. Involved in the formation of the fibrovascular tissues in association with MMP14. PEX, the C-terminal non-catalytic fragment of MMP2, posseses anti-angiogenic and anti-tumor properties and inhibits cell migration and cell adhesion to FGF2 and vitronectin. Ligand for integrinv/beta3 on the surface of blood vessels. MMP2 isoform 2 mediates the proteolysis of CHUK/IKKA and initiates a primary innate immune response by inducing mitochondrial-nuclear stress signaling with activation of the pro-inflammatory NF-kappaB, NFAT and IRF transcriptional pathways. Catalytic activity of MMP2 causes cleavage of gelatin type I and collagen types IV, V, VII, X. Cleaves the collagen-like sequence Pro-Gln-Gly-|-Ile-Ala-Gly-Gln. (Ref: uniprot.org).
VE:
1 * 100 µG
Lieferant:
COMBI-BLOCKS
Beschreibung:
Ethyl(tetrahydropyran-4-yliden)acetat
Artikel-Nr:
(FLUO023025-1G)
Lieferant:
FLUOROCHEM
Hersteller-Artikelnummer::
023025-1G
Lokale Artikelnummer::
FLUO023025-1G
Beschreibung:
Ethyl(4-(dimethylamino)benzoyl)formiat
VE:
1 * 1 g
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Lieferant:
Corning
Beschreibung:
The Corning® Matrigel® Matrix 3-D plate is a high throughput pre-coated format that contains Matrigel that can be used for drug discovery applications with 3-D cell cultures such as organoids, spheroids or tumoroids.
Artikel-Nr:
(PRSI30-997)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
30-997
Lokale Artikelnummer::
PRSI30-997
Beschreibung:
Suppression of the expression of TRAP1 in mitochondria might play an important role in the induction of apoptosis caused via formation of ROS.
VE:
1 * 100 µG
Artikel-Nr:
(PRSI26-110)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
26-110
Lokale Artikelnummer::
PRSI26-110
Beschreibung:
BOP1 is the component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome.
VE:
1 * 50 µG
Lieferant:
COMBI-BLOCKS
Beschreibung:
3-Brom-N-ethyl-4-fluorbenzamid
Lieferant:
COMBI-BLOCKS
Beschreibung:
2-Brom-N-ethyl-5-fluorbenzamid
Artikel-Nr:
(PRSI27-123)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
27-123
Lokale Artikelnummer::
PRSI27-123
Beschreibung:
UBE2K belongs to the ubiquitin-conjugating enzyme family. This protein interacts with RING finger proteins, and it can ubiquitinate huntingtin, the gene product for Huntington's disease. Known functions for this protein include a role in aggregate formation of expanded polyglutamine proteins and the suppression of apoptosis in polyglutamine diseases, a role in the dislocation of newly synthesized MHC class I heavy chains from the endoplasmic reticulum, and involvement in foam cell formation.The protein encoded by this gene belongs to the ubiquitin-conjugating enzyme family. This protein interacts with RING finger proteins, and it can ubiquitinate huntingtin, the gene product for Huntington's disease. Known functions for this protein include a role in aggregate formation of expanded polyglutamine proteins and the suppression of apoptosis in polyglutamine diseases, a role in the dislocation of newly synthesized MHC class I heavy chains from the endoplasmic reticulum, and involvement in foam cell formation. Multiple transcript variants encoding different isoforms have been identified for this gene.
VE:
1 * 50 µG
Lieferant:
Sigma-Aldrich
Beschreibung:
4-[2-(Dimethylamino)ethyl]phenol, Sigma-Aldrich®
Lieferant:
FLUOROCHEM
Beschreibung:
5'-Ethyl-2'-hydroxy-3'-nitroacetophenon
Artikel-Nr:
(PRSI25-594)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
25-594
Lokale Artikelnummer::
PRSI25-594
Beschreibung:
Type I protein arginine N-methyltransferases (PRMTs), such as PRMT3, catalyze the formation of asymmetric N (G),N (G)-dimethylarginine (ADMA) residues in proteins.Type I protein arginine N-methyltransferases (PRMTs), such as PRMT3, catalyze the formation of asymmetric N (G),N (G)-dimethylarginine (ADMA) residues in proteins (Tang et al., 1998 [PubMed 9642256]).
VE:
1 * 50 µG
Artikel-Nr:
(PRSI30-629)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
30-629
Lokale Artikelnummer::
PRSI30-629
Beschreibung:
C1D is a DNA binding and apoptosis-inducing protein and is localized in the nucleus. It is also a Rac3-interacting protein which acts as a corepressor for the thyroid hormone receptor. C1D is thought to regulate TRAX/Translin complex formation. The protein encoded by this gene is a DNA binding and apoptosis-inducing protein and is localized in the nucleus. It is also a Rac3-interacting protein which acts as a corepressor for the thyroid hormone receptor. This protein is thought to regulate TRAX/Translin complex formation. Several alternatively spliced transcript variants of this gene have been described, but the full length nature of some of these variants has not been determined.The protein encoded by this gene is a DNA binding and apoptosis-inducing protein and is localized in the nucleus. It is also a Rac3-interacting protein which acts as a corepressor for the thyroid hormone receptor. This protein is thought to regulate TRAX/Translin complex formation. Several alternatively spliced transcript variants of this gene have been described, but the full length nature of some of these variants has not been determined.The protein encoded by this gene is a DNA binding and apoptosis-inducing protein and is localized in the nucleus. It is also a Rac3-interacting protein which acts as a corepressor for the thyroid hormone receptor. This protein is thought to regulate TRAX/Translin complex formation. Several alternatively spliced transcript variants of this gene have been described, but the full length nature of some of these variants has not been determined.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI92-278)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
92-278
Lokale Artikelnummer::
PRSI92-278
Beschreibung:
Cytochrome b-c1 complex subunit 6, mitochondrial (UQCRH) belongs to the UQCRH/QCR6 family, it is a subunit of the respiratory chain protein Ubiquinol Cytochrome c Reductase. This is a component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is part of the mitochondrial respiratory chain. UQCRH may mediate formation of the complex between cytochromes c and c1. It may mediate formation of the complex between cytochromes c and c1.
VE:
1 * 50 µG
Artikel-Nr:
(COBBPN-8817-1G)
Lieferant:
COMBI-BLOCKS
Hersteller-Artikelnummer::
PN-8817-1G
Lokale Artikelnummer::
COBBPN-8817-1G
Beschreibung:
1-Ethyl-1H-pyrazol-4-boronsäurepinakolester
VE:
1 * 1 g
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Lieferant:
CHEMPUR SILANE
Beschreibung:
Ethyl(trimethylsilyl)acetat
Preis auf Anfrage
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