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2-Bromo-5-fluorobenzo[b]furan-3(2H)-one
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2-Bromo-5-fluorobenzo[b]furan-3(2H)-one
Artikel-Nr:
(BOSSBS-8662R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-8662R
Lokale Artikelnummer::
BOSSBS-8662R
Beschreibung:
Neuronal axonal membrane protein Nap-22, also designated neuronal tissue-enriched acidic protein or brain acid soluble protein (BASP1), is a Ca2+-dependent calmodulin-binding protein that is important for neuronal sprouting and plasticity. Nap-22 is abundant in brain nerve terminals and is also present in significant amounts in kidney, testis and lymphoid tissue. Nap-22 undergoes N-terminal myristoylation for membrane localization. It has been characterized as a major protein of neuronal rafts, which are known to preferentially bind membranes containing cholesterol. Nap-22 is a crucial protein active in neurite outgrowth and synaptic plasticity.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11413R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11413R-A750
Lokale Artikelnummer::
BOSSBS-11413R-A750
Beschreibung:
TSKS is a 592 amino acid protein that is highly expressed in human testicular tissue. Low levels of TSKS are detectable in prostate, placenta, fetal liver, thymus, and mammary gland tissues. TSKS is found to be downregulated in cancerous testicular tissue from seminoma, teratocarcinoma, embryonal and Leydig cell tumours concurrently with high expression in neighboring premalignant carcinoma. TSKS protein contains an N-terminal signal peptide, but does not contain a transmembrane region. TSKS has many potential phosphorylation and glycosylation sites and is phosphorylated by soluble recombinant TSSK2 in vitro. It is thought that TSKS likely plays a physiological role in spermatogenesis or spermiogenesis.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-2976R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-2976R-A750
Lokale Artikelnummer::
BOSSBS-2976R-A750
Beschreibung:
Cleaves the gamma-glutamyl bond of extracellular glutathione (gamma-Glu-Cys-Gly), glutathione conjugates, and other gamma-glutamyl compounds. The metabolism of glutathione releases free glutamate and the dipeptide, cysteinyl-glycine, which is hydrolysed to cysteine and glycine by dipeptidases. In the presence of high concentrations of dipeptides and some amino acids, can also catalyse a transpeptidation reaction, transferring the gamma-glutamyl moiety to an acceptor amino acid to form a new gamma-glutamyl compound. Initiates extracellular glutathione (GSH) breakdown, provides cells with a local cysteine supply and contributes to maintain intracellular GSH level. It is part of the cell antioxidant defence mechanism. Isoform 3 seems to be inactive.
VE:
1 * 100 µl
Artikel-Nr:
(USBIH5110-08V4)
Lieferant:
US Biological
Hersteller-Artikelnummer::
H5110-08V4
Lokale Artikelnummer::
USBIH5110-08V4
Beschreibung:
Anti-Histone H2A.X, gamma Rabbit polyclonal antibody
VE:
1 * 100 µl
Artikel-Nr:
(USBIG8576-88C)
Lieferant:
US Biological
Hersteller-Artikelnummer::
G8576-88C
Lokale Artikelnummer::
USBIG8576-88C
Beschreibung:
Anti-Golgi Associated, Gamma Adaptin Ear Containing, ARF Binding Protein 3 Goat Polyclonal Antibody
VE:
1 * 100 µG
Artikel-Nr:
(BOSSBS-12958R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12958R-CY3
Lokale Artikelnummer::
BOSSBS-12958R-CY3
Beschreibung:
Iron metabolism is essential for sustaining mammalian homeostasis. Iron uptake and distribution is a highly regulated process in mammalian cells that is monitored by two iron sensing proteins; iron regulatory protein-1 and -2 (IRP-1 and -2), also known as iron responsive element-binding protein-1 and -2 (IRE–BP-1 and -2) or aconitase 1 and 2. IRP-1 and IRP-2 are important soluble regulatory factors that mediate iron uptake and storage in mammalian cells. They are capable of either repressing translation or enhancing mRNA stability by associating with stem-loop motifs known as iron-responsive elements (IREs). IRPs respond to stress mediators, iron concentration and signaling factors, including nitrogen monoxide, cytokines and hydrogen peroxide.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-4224R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-4224R-A680
Lokale Artikelnummer::
BOSSBS-4224R-A680
Beschreibung:
UGT1A9 is a UDP glucuronosyltransferase, an enzyme of the glucuronidation pathway that transforms small lipophilic molecules, such as steroids, bilirubin, hormones, and drugs, into water soluble, excretable metabolites. This gene is part of a complex locus that encodes several UDP glucuronosyltransferases. The locus includes thirteen unique alternate first exons followed by four common exons. Four of the alternate first exons are considered pseudogenes. Each of the remaining nine 5' exons may be spliced to the four common exons, resulting in nine proteins with different N termini and identical C termini. Each first exon encodes the substrate binding site, and is regulated by its own promoter. UGT1A9 is active on phenols.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-13493R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13493R-CY3
Lokale Artikelnummer::
BOSSBS-13493R-CY3
Beschreibung:
Involved in transport from the ER to the Golgi apparatus as well as in intra-Golgi transport. It belongs to a super-family of proteins called t-SNAREs or soluble NSF (N-ethylmaleimide-sensitive factor) attachment protein receptor. May play a protective role against hydrogen peroxide induced cytotoxicity under glutathione depleted conditions in neuronal cells by regulating the intracellular ROS levels via inhibition of p38 MAPK (MAPK11, MAPK12, MAPK13 and MAPK14). Participates in docking and fusion stage of ER to cis-Golgi transport. Plays an important physiological role in VLDL-transport vesicle-Golgi fusion and thus in VLDL delivery to the hepatic cis-Golgi.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-12958R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12958R-CY7
Lokale Artikelnummer::
BOSSBS-12958R-CY7
Beschreibung:
Iron metabolism is essential for sustaining mammalian homeostasis. Iron uptake and distribution is a highly regulated process in mammalian cells that is monitored by two iron sensing proteins; iron regulatory protein-1 and -2 (IRP-1 and -2), also known as iron responsive element-binding protein-1 and -2 (IRE–BP-1 and -2) or aconitase 1 and 2. IRP-1 and IRP-2 are important soluble regulatory factors that mediate iron uptake and storage in mammalian cells. They are capable of either repressing translation or enhancing mRNA stability by associating with stem-loop motifs known as iron-responsive elements (IREs). IRPs respond to stress mediators, iron concentration and signaling factors, including nitrogen monoxide, cytokines and hydrogen peroxide.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-12957R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12957R-CY3
Lokale Artikelnummer::
BOSSBS-12957R-CY3
Beschreibung:
Iron metabolism is essential for sustaining mammalian homeostasis. Iron uptake and distribution is a highly regulated process in mammalian cells that is monitored by two iron sensing proteins; iron regulatory protein-1 and -2 (IRP-1 and -2), also known as iron responsive element-binding protein-1 and -2 (IRE–BP-1 and -2) or aconitase 1 and 2. IRP-1 and IRP-2 are important soluble regulatory factors that mediate iron uptake and storage in mammalian cells. They are capable of either repressing translation or enhancing mRNA stability by associating with stem-loop motifs known as iron-responsive elements (IREs). IRPs respond to stress mediators, iron concentration and signaling factors, including nitrogen monoxide, cytokines and hydrogen peroxide.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-6058R-CY5.5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6058R-CY5.5
Lokale Artikelnummer::
BOSSBS-6058R-CY5.5
Beschreibung:
Essential subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors and APP (beta-amyloid precursor protein). It probably represents a stabilizing cofactor required for the assembly of the gamma-secretase complex.
VE:
1 * 100 µl
Lieferant:
IKA
Beschreibung:
ST-20 und ST-50 Röhrchen bestehend aus Röhrchen, Rührvorrichtung und Verschluss.
Lieferant:
MP Biomedicals
Beschreibung:
Dextran is a high molecular weight polymer of anhydroglucose. It is composed of approximately 95% alpha-D-(1-->6) linkages. The remaining a(1-->3) linkages account for the branching of dextran.
Dextrans are used in many applications as volume extenders, stabilizers, matrix components, binding platforms, lubricants and physical structure components.
Lieferant:
Thermo Fisher Scientific
Beschreibung:
Die saure Funktionalität in der Polymerstruktur ermöglicht die Analyse saurer Verbindungen ohne Derivatisierung.
Artikel-Nr:
(BOSSBS-0037R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0037R-CY3
Lokale Artikelnummer::
BOSSBS-0037R-CY3
Beschreibung:
Functions both as NADH oxidoreductase and as regulator of apoptosis. In response to apoptotic stimuli, it is released from the mitochondrion intermembrane space into the cytosol and to the nucleus, where it functions as a proapoptotic factor in a caspase-independent pathway. In contrast, functions as an antiapoptotic factor in normal mitochondria via its NADH oxidoreductase activity. The soluble form (AIFsol) found in the nucleus induces 'parthanatos' i.e. caspase-independent fragmentation of chromosomal DNA. Interacts with EIF3G,and thereby inhibits the EIF3 machinery and protein synthesis, and activates casapse-7 to amplify apoptosis. Plays a critical role in caspase-independent, pyknotic cell death in hydrogen peroxide-exposed cells. Binds to DNA in a sequence-independent manner.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-0037R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0037R-CY5
Lokale Artikelnummer::
BOSSBS-0037R-CY5
Beschreibung:
Functions both as NADH oxidoreductase and as regulator of apoptosis. In response to apoptotic stimuli, it is released from the mitochondrion intermembrane space into the cytosol and to the nucleus, where it functions as a proapoptotic factor in a caspase-independent pathway. In contrast, functions as an antiapoptotic factor in normal mitochondria via its NADH oxidoreductase activity. The soluble form (AIFsol) found in the nucleus induces 'parthanatos' i.e. caspase-independent fragmentation of chromosomal DNA. Interacts with EIF3G,and thereby inhibits the EIF3 machinery and protein synthesis, and activates casapse-7 to amplify apoptosis. Plays a critical role in caspase-independent, pyknotic cell death in hydrogen peroxide-exposed cells. Binds to DNA in a sequence-independent manner.
VE:
1 * 100 µl
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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