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2-Chlor-6-fluor-3-methoxybenzylamin
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2-Chlor-6-fluor-3-methoxybenzylamin
Artikel-Nr:
(BOSSBS-0055R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0055R-A555
Lokale Artikelnummer::
BOSSBS-0055R-A555
Beschreibung:
Ligand for the GFR-alpha-3-RET receptor complex but can also activate the GFR-alpha-1-RET receptor complex. Supports the survival of sensory and sympathetic peripheral neurons in culture and also supports the survival of dopaminergic neurons of the ventral mid-brain (By similarity). Strong attractant of gut hematopoietic cells thus promoting the formation Peyer's patch-like structures, a major component of the gut-associated lymphoid tissue.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-7865R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-7865R-A647
Lokale Artikelnummer::
BOSSBS-7865R-A647
Beschreibung:
Guanine nucleotide dissociation inhibitor (GDI) which functions as a receptor-independent activator of heterotrimeric G-protein signaling. Keeps G(i/o) alpha subunit in its GDP-bound form thus uncoupling heterotrimeric G-proteins signaling from G protein-coupled receptors. Controls spindle orientation and asymmetric cell fate of cerebral cortical progenitors. May also be involved in macroautophagy in intestinal cells. May play a role in drug addiction.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-14371R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-14371R-A750
Lokale Artikelnummer::
BOSSBS-14371R-A750
Beschreibung:
DNAJB12 belongs to the evolutionarily conserved DNAJ/HSP40 family of proteins, which regulate molecular chaperone activity by stimulating ATPase activity. DNAJ proteins may have up to 3 distinct domains: a conserved 70-amino acid J domain, usually at the N terminus; a glycine/phenylalanine (G/F)-rich region; and a cysteine-rich domain containing 4 motifs resembling a zinc finger domain (Ohtsuka and Hata, 2000 [PubMed 11147971]).[supplied by OMIM, Mar 2008]
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-2637R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-2637R-A680
Lokale Artikelnummer::
BOSSBS-2637R-A680
Beschreibung:
The protein encoded by this gene is a member of the MAPkinase family. MAP kinases, also known as extracellularsignal-regulated kinases (ERKs), act in a signaling cascade thatregulates various cellular processes such as proliferation,differentiation, and cell cycle progression in response to avariety of extracellular signals. This kinase is activated byupstream kinases, resulting in its translocation to the nucleuswhere it phosphorylates nuclear targets. Alternatively splicedtranscript variants encoding different protein isoforms have beendescribed.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5786R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5786R-A555
Lokale Artikelnummer::
BOSSBS-5786R-A555
Beschreibung:
Kallistatin is a serine proteinase inhibitor which binds to tissue kallikrein and inhibits its amidolytic and kininogenase activity. Inhibition is achieved by formation of an equimolar, heat- and SDS-stable complex between the inhibitor and the enzyme, and generation of a small C-terminal fragment of the inhibitor due to cleavage at the reactive site by tissue kallikrein. Heparin blocks kallistatin's complex formation with tissue kallikrein and abolishes its inhibitory effect on tissue kallikrein's activity.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-2928R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-2928R-A488
Lokale Artikelnummer::
BOSSBS-2928R-A488
Beschreibung:
The protein encoded by this gene contains a PDZ domain and a LIM domain, indicating that it may be involved in cytoskeletal assembly. In support of this, the encoded protein has been shown to bind the spectrin-like repeats of alpha-actinin-2 and to colocalize with alpha-actinin-2 at the Z lines of skeletal muscle. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. Aberrant alternative splicing of this gene may play a role in myotonic dystrophy.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3122R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3122R-A488
Lokale Artikelnummer::
BOSSBS-3122R-A488
Beschreibung:
The protein encoded by this gene is a regulatory protein involved in mitosis. The gene product complexes with p34(cdc2) to form the maturation-promoting factor (MPF). Two alternative transcripts have been found, a constitutively expressed transcript and a cell cycle-regulated transcript, that is expressed predominantly during G2/M phase. The different transcripts result from the use of alternate transcription initiation sites. [provided by RefSeq, Jul 2008].
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-13254R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13254R-A350
Lokale Artikelnummer::
BOSSBS-13254R-A350
Beschreibung:
This gene encodes acid alpha-glucosidase, which is essential for the degradation of glycogen to glucose in lysosomes. Different forms of acid alpha-glucosidase are obtained by proteolytic processing. Defects in this gene are the cause of glycogen storage disease II, also known as Pompe's disease, which is an autosomal recessive disorder with a broad clinical spectrum. Three transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008].
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-8048R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-8048R-A647
Lokale Artikelnummer::
BOSSBS-8048R-A647
Beschreibung:
Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex required for efficient chromosome alignment and cytokinesis. The BCR(KLHL21) E3 ubiquitin ligase complex regulates localization of the chromosomal passenger complex (CPC) from chromosomes to the spindle midzone in anaphase and mediates the ubiquitination of AURKB. Ubiquitination of AURKB by BCR(KLHL21) E3 ubiquitin ligase complex may not lead to its degradation by the proteasome.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9172R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9172R-A350
Lokale Artikelnummer::
BOSSBS-9172R-A350
Beschreibung:
The protein encoded by this gene contains a RING-H2 finger motif. Deletions and mutations in this gene were detected in esophageal squamous cell carcinoma (ESCC), suggesting that this protein may be a potential tumor suppressor. Studies of the mouse counterpart suggested a role of this protein in the transcription regulation that controls germinal differentiation. Multiple alternatively spliced transcript variants encoding the same protein are observed. [provided by RefSeq, Jul 2008].
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-4140R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-4140R-A350
Lokale Artikelnummer::
BOSSBS-4140R-A350
Beschreibung:
This gene product appears to function as a negative regulator of the ras signal transduction pathway. Mutations in this gene have been linked to neurofibromatosis type 1, juvenile myelomonocytic leukemia and Watson syndrome. The mRNA for this gene is subject to RNA editing (CGA>UGA->Arg1306Term) resulting in premature translation termination. Alternatively spliced transcript variants encoding different isoforms have also been described for this gene. [provided by RefSeq, Jul 2008].
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-0813R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0813R-A350
Lokale Artikelnummer::
BOSSBS-0813R-A350
Beschreibung:
Casein is the name for a family of related phosphoproteins. These proteins are commonly found in mammalian milk, making up 80% of the proteins in cow milk and between 20% and 45% of the proteins in human milk. Casein has a wide variety of uses, from being a major component of cheese, to use as a food additive, to a binder for safety matches. As a food source, casein supplies amino acids; carbohydrates; and two inorganic elements, calcium and phosphorus.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-2937R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-2937R-A647
Lokale Artikelnummer::
BOSSBS-2937R-A647
Beschreibung:
This gene encodes the beta subunit of casein kinase II, a ubiquitous protein kinase which regulates metabolic pathways, signal transduction, transcription, translation, and replication. The enzyme is composed of three subunits, alpha, alpha prime and beta, which form a tetrameric holoenzyme. The alpha and alpha prime subunits are catalytic, while the beta subunit serves regulatory functions. The enzyme localizes to the endoplasmic reticulum and the Golgi apparatus. [provided by RefSeq, Jul 2008].
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5786R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5786R-A488
Lokale Artikelnummer::
BOSSBS-5786R-A488
Beschreibung:
Kallistatin is a serine proteinase inhibitor which binds to tissue kallikrein and inhibits its amidolytic and kininogenase activity. Inhibition is achieved by formation of an equimolar, heat- and SDS-stable complex between the inhibitor and the enzyme, and generation of a small C-terminal fragment of the inhibitor due to cleavage at the reactive site by tissue kallikrein. Heparin blocks kallistatin's complex formation with tissue kallikrein and abolishes its inhibitory effect on tissue kallikrein's activity.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5816R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5816R-A750
Lokale Artikelnummer::
BOSSBS-5816R-A750
Beschreibung:
Involved in the RCC1/Ran-GTPase pathway. RRAGA may play a direct role in a TNF-alpha signaling pathway leading to induction of cell death. May alternatively act as a cellular target for adenovirus E3-14.7K, an inhibitor of TNF-alpha functions, thereby affecting cell death. Has guanine nucleotide-binding activity but undetectable intrinsic GTPase activity. biquitously expressed with highest levels of expression in skeletal muscle, heart, and brain.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-0538R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0538R-A488
Lokale Artikelnummer::
BOSSBS-0538R-A488
Beschreibung:
This gene is imprinted, with preferential expression of the maternal allele. The encoded protein is a tight-binding, strong inhibitor of several G1 cyclin/Cdk complexes and a negative regulator of cell proliferation. Mutations in this gene are implicated in sporadic cancers and Beckwith-Wiedemann syndorome, suggesting that this gene is a tumor suppressor candidate. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Oct 2010].
VE:
1 * 100 µl
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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