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2-Chlor-6-fluor-3-methoxybenzylamin
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2-Chlor-6-fluor-3-methoxybenzylamin
Artikel-Nr:
(BOSSBS-12990R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12990R-A555
Lokale Artikelnummer::
BOSSBS-12990R-A555
Beschreibung:
Binds to and inhibits the transcriptional repressor ZBTB33, which may lead to activation of target genes of the Wnt signaling pathway (By similarity). May associate with and regulate the cell adhesion properties of both C- and E-cadherins. Implicated both in cell transformation by SRC and in ligand-induced receptor signaling through the EGF, PDGF, CSF-1 and ERBB2 receptors. Promotes GLIS2 C-terminal cleavage.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-1424R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1424R-A350
Lokale Artikelnummer::
BOSSBS-1424R-A350
Beschreibung:
Receptor for erythropoietin. Mediates erythropoietin-induced erythroblast proliferation and differentiation. Upon EPO stimulation, EPOR dimerizes triggering the JAK2/STAT5 signaling cascade. In some cell types, can also activate STAT1 and STAT3. May also activate the LYN tyrosine kinase. Isoform EPOR-T acts as a dominant-negative receptor of EPOR-mediated signaling.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-8331R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-8331R-A680
Lokale Artikelnummer::
BOSSBS-8331R-A680
Beschreibung:
CPXCR1 is widely expressed in fetal tissues, including the tongue, mandible and palate with an unknown function. Cleft palate most commonly occurs as a sporadic multifactorial disorder with a clear but difficult to define genetic component. As a semi-dominant disorder, X-linked cleft palate (CPX) provides a useful model to investigate a congenital defect that is little influenced by non-genetic factors.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5899R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5899R-A555
Lokale Artikelnummer::
BOSSBS-5899R-A555
Beschreibung:
Catalyzes the post-translational formation of 4-hydroxyproline in hypoxia-inducible factor (HIF) alpha proteins. Hydroxylates HIF1A at 'Pro-402' and 'Pro-564'. May function as a cellular oxygen sensor and, under normoxic conditions, may target HIF through the hydroxylation for proteasomal degradation via the von Hippel-Lindau ubiquitination complex.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-4185R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-4185R-A680
Lokale Artikelnummer::
BOSSBS-4185R-A680
Beschreibung:
The NFKB complex consists of NFKB1 or NFKB2 bound to REL, RELA, or RELB. The NFKB complex is inhibited by I kappa B proteins (NFKBIA, or NFKBIB), which inactivate NF kappa B by trapping it in the cytoplasm. Phosphorylation of serine residues on the I kappa B proteins by kinases (IKBKA, or IKBKB,) marks them for destruction via the ubiquitination pathway, thereby allowing activation of the NF kappa B complex.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-2680R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-2680R-A555
Lokale Artikelnummer::
BOSSBS-2680R-A555
Beschreibung:
May function in immune system as a receptor which activates via the calcineurin/NFAT-signaling pathway the downstream cytokine gene promoters. Activates the transcription of IL-13 and TNF-alpha promoters. May be involved in the regulation of B-cell, but not T-cell, development. Overexpression activates downstream effectors without ligand binding or antibody cross-linking.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-2075R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-2075R-A555
Lokale Artikelnummer::
BOSSBS-2075R-A555
Beschreibung:
Heme oxygenase cleaves the heme ring at the alpha methene bridge to form biliverdin. Biliverdin is subsequently converted to bilirubin by biliverdin reductase. Under physiological conditions, the activity of heme oxygenase is highest in the spleen, where senescent erythrocytes are sequestrated and destroyed. Exhibits cytoprotective effects since excess of free heme sensitizes cells to undergo apoptosis.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3052R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3052R-A555
Lokale Artikelnummer::
BOSSBS-3052R-A555
Beschreibung:
Suppresses apoptosis in a variety of cell systems including factor-dependent lymphohematopoietic and neural cells. Regulates cell death by controlling the mitochondrial membrane permeability. Appears to function in a feedback loop system with caspases. Inhibits caspase activity either by preventing the release of cytochrome c from the mitochondria and/or by binding to the apoptosis-activating factor (APAF-1).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9046R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9046R-A750
Lokale Artikelnummer::
BOSSBS-9046R-A750
Beschreibung:
The product of this gene belongs to the family of transient receptor potential (TRP) channels. TRP channels are cation-selective channels important for cellular calcium signaling and homeostasis. The protein encoded by this gene mediates calcium entry, and this entry is potentiated by calcium store depletion. Alternatively spliced transcript variants encoding different isoforms have been identified.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-1586R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1586R-A488
Lokale Artikelnummer::
BOSSBS-1586R-A488
Beschreibung:
Growth factor active in angiogenesis, and endothelial cell growth, stimulating their proliferation and migration and also has effects on the permeability of blood vessels. May function in angiogenesis of the venous and lymphatic vascular systems during embryogenesis, and also in the maintenance of differentiated lymphatic endothelium in adults. Binds and activates VEGFR-2 (KDR/FLK1) and VEGFR-3 (FLT4) receptors.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-4057R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-4057R-A350
Lokale Artikelnummer::
BOSSBS-4057R-A350
Beschreibung:
DEGS1 is a member of the membrane fatty acid desaturase family which is responsible for inserting double bonds into specific positions in fatty acids. It contains three His containing consensus motifs that are characteristic of a group of membrane fatty acid desaturases. It has sphingolipid-delta-4-desaturase activity and converts D-erythro-sphinganine to D-erythro-sphingosine (E-sphing-4-enine).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9060R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9060R-A647
Lokale Artikelnummer::
BOSSBS-9060R-A647
Beschreibung:
Participates in Wnt signaling by binding to the cytoplasmic C-terminus of frizzled family members and transducing the Wnt signal to down-stream effectors. Promotes internalization and degradation of frizzled proteins upon Wnt signaling. Plays a role both in canonical and non-canonical Wnt signaling. Plays a role in the signal transduction pathways mediated by multiple Wnt genes (By similarity).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-4905R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-4905R-A350
Lokale Artikelnummer::
BOSSBS-4905R-A350
Beschreibung:
Adapter protein that plays a role in the assembling of signaling complexes, being a link between ABL kinases and actin cytoskeleton. Can form complex with ABL1 and CBL, thus promoting ubiquitination and degradation of ABL1 or with AKT1 and PAK1, thus mediating AKT1-mediated activation of PAK1. Isoform 6 increases water and sodium absorption in the intestine and gall-bladder.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-1932R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1932R-A555
Lokale Artikelnummer::
BOSSBS-1932R-A555
Beschreibung:
Vitronectin is a cell adhesion and spreading factor found in serum and tissues. Vitronectin interact with glycosaminoglycans and proteoglycans. Is recognized by certain members of the integrin family and serves as a cell-to-substrate adhesion molecule. Inhibitor of the membrane-damaging effect of the terminal cytolytic complement pathway. Somatomedin-B is a growth hormone-dependent serum factor with protease-inhibiting activity.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5841R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5841R-A647
Lokale Artikelnummer::
BOSSBS-5841R-A647
Beschreibung:
MGAT5 is a mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase, a glycosyltransferase involved in the synthesis of protein-bound and lipid-bound oligosaccharides. Alterations of the oligosaccharides on cell surface glycoproteins cause significant changes in the adhesive or migratory behavior of a cell. Increase in the encoded protein's activity may correlate with the progression of invasive malignancies.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-7754R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-7754R-A647
Lokale Artikelnummer::
BOSSBS-7754R-A647
Beschreibung:
Probable molecular chaperone. Assists the folding of proteins upon ATP hydrolysis. As part of the BBS/CCT complex may play a role in the assembly of BBSome, a complex involved in ciliogenesis regulating transports vesicles to the cilia. May play a role in protein processing in limb, cardiac and reproductive system development. May play a role in cytokinesis.
VE:
1 * 100 µl
Preis auf Anfrage
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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