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SCHNEIDER LUDWIG
Artikel-Nr:
(BOSSBS-11869R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11869R-A680
Lokale Artikelnummer::
BOSSBS-11869R-A680
Beschreibung:
Leukocyte cell-derived chemotaxin 2 (LECT2) is a secreted protein with a neutrophil chemotactic activity. LECT2 is highly expressed in liver and shows diffuse immunostaining within the cytoplasm of hepatocytes. The LECT2 protein consists of 133 amino acids and three intramolecular disulfide bonds, and homologues of LECT2 have been widely identified in many vertebrates. LECT2 has a multifunctional role that extends from cell growth, differentiation, damage/repair process and carcinogenesis to autoimmune diseases. LECT2 expression is specifically induced in liver by catenin Signalling. Serum LECT2 levels have been shown to increase in response to liver recovery, suggesting LECT2 may be used as a prognostic indicator.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-2672R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-2672R-A555
Lokale Artikelnummer::
BOSSBS-2672R-A555
Beschreibung:
The protein encoded by this gene, a member of the peptidase C1 family, is a lysosomal cysteine proteinase that appears to be a central coordinator for activation of many serine proteinases in immune/inflammatory cells. It is composed of a dimer of disulfide-linked heavy and light chains, both produced from a single protein precursor, and a residual portion of the propeptide acts as an intramolecular chaperone for the folding and stabilization of the mature enzyme. This enzyme requires chloride ions for activity and can degrade glucagon. Defects in the encoded protein have been shown to be a cause of Papillon-Lefevre syndrome, an autosomal recessive disorder characterized by palmoplantar keratosis and periodontitis. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq].
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-2672R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-2672R-A647
Lokale Artikelnummer::
BOSSBS-2672R-A647
Beschreibung:
The protein encoded by this gene, a member of the peptidase C1 family, is a lysosomal cysteine proteinase that appears to be a central coordinator for activation of many serine proteinases in immune/inflammatory cells. It is composed of a dimer of disulfide-linked heavy and light chains, both produced from a single protein precursor, and a residual portion of the propeptide acts as an intramolecular chaperone for the folding and stabilization of the mature enzyme. This enzyme requires chloride ions for activity and can degrade glucagon. Defects in the encoded protein have been shown to be a cause of Papillon-Lefevre syndrome, an autosomal recessive disorder characterized by palmoplantar keratosis and periodontitis. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq].
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-7945R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-7945R-CY7
Lokale Artikelnummer::
BOSSBS-7945R-CY7
Beschreibung:
ABHD14B has hydrolase activity towards p-nitrophenyl butyrate (in vitro). It may activate transcription. There are 2 isoforms produced by alternative splicing.
VE:
1 * 100 µl
Lieferant:
Biotium
Beschreibung:
This MAb recognizes proteins of 19-22 kDa (reducing) and 38 kDa-44 kDa (non-reducing), identified as various isoforms of Vascular Endothelial Growth Factor or Vascular Permeability Factor (VEGF/VPF). It is highly specific to VEGF, which is a homodimeric, disulfide-linked glycoprotein with a close homology to platelet derived growth factor (PDGF). There are multiple isoforms of VEGF containing 206-, 189-, 165-, and 121-amino acid residues. The smaller two isoforms, VEGF165 and VEGF121, are secreted proteins and act as diffusible agents, whereas the larger two remain cell associated. VEGF/VPF plays an important role in angiogenesis, which promotes tumor progression and metastasis.
Lieferant:
Biotium
Beschreibung:
This MAb recognizes proteins of 19-22 kDa (reducing) and 38 kDa-44 kDa (non-reducing), identified as various isoforms of Vascular Endothelial Growth Factor or Vascular Permeability Factor (VEGF/VPF). It is highly specific to VEGF, which is a homodimeric, disulfide-linked glycoprotein with a close homology to platelet derived growth factor (PDGF). There are multiple isoforms of VEGF containing 206-, 189-, 165-, and 121-amino acid residues. The smaller two isoforms, VEGF165 and VEGF121, are secreted proteins and act as diffusible agents, whereas the larger two remain cell associated. VEGF/VPF plays an important role in angiogenesis, which promotes tumor progression and metastasis.
Artikel-Nr:
(BOSSBSM-0862M-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BSM-0862M-A750
Lokale Artikelnummer::
BOSSBSM-0862M-A750
Beschreibung:
Insulin is a pancreatic hormone that regulates glucose and is involved in the synthesis of protein and fat. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. Heterodimer of a B chain and an A chain linked by two disulfide bonds.Belongs to the insulin family. The insulin-link growth factors, IGF-I and IGF-II (also desinated somatomedin C and multiplication stimulating activator, respectvely), share approximatly 76% sequence identity and are 50% related to pro-insulin.IGF-I and IGF-II are nonglycosylated, single chain proteins of 70 and 76 amino acids in length, respectivelly. IGF-I functions as an autocrine regulator of growth in vaious, whereas the function of IGF-II is less well defined.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-10722R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-10722R-CY7
Lokale Artikelnummer::
BOSSBS-10722R-CY7
Beschreibung:
Staphylococcal enterotoxins represent a group of proteins, which are secreted by Staphylococcus aureus and cause staphylococcal food poisoning syndrome. The illness is characterised by high fever, hypotension, diarrhea, shock, and in some cases death. Their molecular masses range between 27 and 30 kDa. At present, seven enterotoxins are known, namely A, B, C1, C2, C3, D and E. Their amino acid sequences have been determined and it was shown that all are single chain polypeptides containing one disulfide bond formed by two half cystines located in the middle of the polypeptide chain, which form the so called cysteine loop. SEB is an extremely potent activator of T cells, stimulating the production and secretion of various cytokines which mediate many of the toxic effects of SEB.
VE:
1 * 100 µl
Artikel-Nr:
(BSENR-089-100)
Lieferant:
Biosensis
Hersteller-Artikelnummer::
R-089-100
Lokale Artikelnummer::
BSENR-089-100
Beschreibung:
FUNCTION: Low affinity receptor which can bind to NGF, BDNF, NT-3, and NT-4. Can mediate cell survival as well as cell death of neural cells. SUBUNIT: Homodimer; disulfide-linked. Interacts with p75NTR-associated cell death executor. Interacts with TRAF2, TRAF4, TRAF6, PTPN13 and RANBP9. Interacts through TRAF6 with SQSTM1 which bridges NGFR to NTRK1. Interacts with BEX1 and NGFRAP1/BEX3. SUBCELLULAR LOCATION: Membrane; single-pass type I membrane protein. DOMAIN: Death domain is responsible for interaction with RANBP9. PTM: N- and O-glycosylated. PTM: O-linked glycans consist of Gal(1-3)GalNAc core elongated by 1 or 2 NeuNAc. PTM: Phosphorylated on serine residues. SIMILARITY: Contains 1 death domain. SIMILARITY: Contains 4 TNFR-Cys repeats.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-13528R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13528R-CY7
Lokale Artikelnummer::
BOSSBS-13528R-CY7
Beschreibung:
G protein-coupled receptors (GPRs) are a protein family of transmembrane receptors that transmit an extracellular signal (ligand binding) into an intracellular signal (G protein activation). GPR signaling is an evolutionarily ancient mechanism used by all eukaryotes to sense environmental stimuli and mediate cell-cell communication. GPRs all have seven membrane-spanning domains and extracellular loops that can be glycosylated. These extracellular loops also contain two highly conserved cysteine residues which create disulfide bonds to stabilize the receptor structure. SREB1 (super conserved receptor expressed in brain 1), also known as GPR27 (G protein-coupled receptor 27), belongs to the SREB subfamily of GPRs that are expressed in the central nervous system. SREB1 may function as an amine-like GPR.
VE:
1 * 100 µl
Artikel-Nr:
(APOSOR1499-250MG)
Lieferant:
APOLLO SCIENTIFIC
Hersteller-Artikelnummer::
OR1499-250MG
Lokale Artikelnummer::
APOSOR1499-250MG
Beschreibung:
2-Amino-4-nitrobenzenemethanol 98%
VE:
1 * 250 mg
Artikel-Nr:
(BLDPBD00752390-5G)
Lieferant:
BLD PHARMATECH GMBH
Hersteller-Artikelnummer::
BD00752390-5G
Lokale Artikelnummer::
BLDPBD00752390-5G
Beschreibung:
3-Fluoro-5-nitrobenzeneboronic acid pinacol ester 98%
VE:
1 * 5 g
Artikel-Nr:
(APOSOR21441-1G)
Lieferant:
APOLLO SCIENTIFIC
Hersteller-Artikelnummer::
OR21441-1G
Lokale Artikelnummer::
APOSOR21441-1G
Beschreibung:
2-Chlor-4'-nitroacetanilid
VE:
1 * 1 g
Artikel-Nr:
(BOSSBS-13528R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13528R-HRP
Lokale Artikelnummer::
BOSSBS-13528R-HRP
Beschreibung:
G protein-coupled receptors (GPRs) are a protein family of transmembrane receptors that transmit an extracellular signal (ligand binding) into an intracellular signal (G protein activation). GPR signaling is an evolutionarily ancient mechanism used by all eukaryotes to sense environmental stimuli and mediate cell-cell communication. GPRs all have seven membrane-spanning domains and extracellular loops that can be glycosylated. These extracellular loops also contain two highly conserved cysteine residues which create disulfide bonds to stabilize the receptor structure. SREB1 (super conserved receptor expressed in brain 1), also known as GPR27 (G protein-coupled receptor 27), belongs to the SREB subfamily of GPRs that are expressed in the central nervous system. SREB1 may function as an amine-like GPR.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-13528R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13528R-A488
Lokale Artikelnummer::
BOSSBS-13528R-A488
Beschreibung:
G protein-coupled receptors (GPRs) are a protein family of transmembrane receptors that transmit an extracellular signal (ligand binding) into an intracellular signal (G protein activation). GPR signaling is an evolutionarily ancient mechanism used by all eukaryotes to sense environmental stimuli and mediate cell-cell communication. GPRs all have seven membrane-spanning domains and extracellular loops that can be glycosylated. These extracellular loops also contain two highly conserved cysteine residues which create disulfide bonds to stabilize the receptor structure. SREB1 (super conserved receptor expressed in brain 1), also known as GPR27 (G protein-coupled receptor 27), belongs to the SREB subfamily of GPRs that are expressed in the central nervous system. SREB1 may function as an amine-like GPR.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11175R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11175R-CY7
Lokale Artikelnummer::
BOSSBS-11175R-CY7
Beschreibung:
Lubricin, also designated proteoglycan-4 or megakaryocyte stimulating factor, is important for boundary lubrication within articulating joints. It is a disulfide-linked homodimer (between Cysteine 1146 and Cysteine 1403) that is essential for protein cleavage. Lubricin inhibits synovial cell adhesion to the cartilage surface, but also prevents the deposition of proteins from synovial fluid onto cartilage. Lubricin is highly expressed in cartilage, liver and synovial tissue. Defects in the gene encoding for lubricin can cause Jakobs syndrome, also designated camptodactyly-arthropathy-coxa vara-pericarditis syndrome (CACP). CACP is an autosomal recessive disorder characterized by joint failure associated with noninflammatory synoviocyte hyperplasia and subinitimal fibrosis of the synovial capsule. Lubricin undergoes different levels of glycosylation and may be detected at varying molecular weights.
VE:
1 * 100 µl
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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