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(Phenylthio)essigs\u00E4ure
Lieferant:
Biotium
Beschreibung:
Recognizes proteins of 33, 35 and 41 kDa, which are identified as various isoforms of CD74. Its epitope is localized in the extracellular domain of CD74. CD74 is a type II transmembrane protein which binds to the peptide binding groove of newly synthesized MHC class II alpha/beta heterodimers and prevents their premature association with endogenous polypeptides. The CD74 molecule plays a critical role in the presentation of peptides, by the MHC class II antigens, to CD4 positive lymphocytes. CD74 is expressed on MHC class II positive cells including B cells, a subset of activated T cells, monocytes, and dendritic cells and by various types of carcinomas. CD74 is expressed primarily by antigen presenting cells, such as B-lymphocytes (from before the pre-B cell stage to before the plasma cell stage), macrophages, and monocytes, and many epithelial cells. Anti-CD74 stains predominantly germinal center lymphocytes and B-cell lymphomas, but rarely T-cell lymphomas. Anti-CD74 has been shown to be useful in differentiating atypical fibroxanthoma (-) from malignant fibrous histiocytoma ( ).
Lieferant:
Biotium
Beschreibung:
Recognizes proteins of 33, 35 and 41 kDa, which are identified as various isoforms of CD74. Its epitope is localized in the extracellular domain of CD74. CD74 is a type II transmembrane protein which binds to the peptide binding groove of newly synthesized MHC class II alpha/beta heterodimers and prevents their premature association with endogenous polypeptides. The CD74 molecule plays a critical role in the presentation of peptides, by the MHC class II antigens, to CD4 positive lymphocytes. CD74 is expressed on MHC class II positive cells including B cells, a subset of activated T cells, monocytes, and dendritic cells and by various types of carcinomas. CD74 is expressed primarily by antigen presenting cells, such as B-lymphocytes (from before the pre-B cell stage to before the plasma cell stage), macrophages, and monocytes, and many epithelial cells. Anti-CD74 stains predominantly germinal center lymphocytes and B-cell lymphomas, but rarely T-cell lymphomas. Anti-CD74 has been shown to be useful in differentiating atypical fibroxanthoma (-) from malignant fibrous histiocytoma ( ).
Artikel-Nr:
(BIBBRO35)
Lieferant:
SciLabware
Hersteller-Artikelnummer::
RO35
Lokale Artikelnummer::
BIBBRO35
Beschreibung:
Made of borosilicate glass.
VE:
1 * 1 ST
Lieferant:
Brand
Beschreibung:
PP oder LDPE, hohl, mit Dichtringen und Vierkant- bzw. Achtkantgriffscheibe.
Lieferant:
Biotium
Beschreibung:
This antibody recognizes a protein of 35 kDa, which is identified as tartrate-resistant acid phosphatase (TRAcP). It exists as two isoforms (5a and 5b). This MAb reacts with both the isoforms. Serum TRAcP 5a is secreted by macrophages and dendritic cells and increased in many patients of rheumatoid arthritis.Serum TRAcP 5b is produced from osteoclasts and elevated during bone resorption. TRAcP is an iron containing glycoprotein, which catalyzes the conversion of orthophosphoric monoester to alcohol and orthophosphate. It is the most basic of the acid phosphatases and is the only form not inhibited by L( )-tartrate. TRAcP is synthesized as a latent proenzyme and is activated by proteolytic cleavage and reduction. Normally, TRAcP is highly expressed by osteoclasts, activated macrophages, neurons and endometrium during pregnancy. Expression of TRAcP is increased in certain pathological conditions such as Leukemic Reticuloendotheliosis (Hairy Cell Leukemia), Gaucher's Disease, HIV-induced Encephalopathy, Osteoclastoma and in osteoporosis and metabolic bone diseases. Anti-TRAcP antibody labels the cells of Hairy Cell Leukemia (HCL) with a high degree of sensitivity and specificity. Other cells stained with this antibody are tissue macrophages and osteoclasts.
Artikel-Nr:
(BURK3490-0355)
Lieferant:
BURKLE
Hersteller-Artikelnummer::
3490-0355
Lokale Artikelnummer::
BURK3490-0355
Beschreibung:
Containers in LDPE, transparent, with lids, for various applications. Produced seamlessly and stress relieved with the LaboPlast® sintering method.
VE:
1 * 1 ST
Artikel-Nr:
(HERA50058602)
Lieferant:
HERAEUS
Hersteller-Artikelnummer::
50058602
Lokale Artikelnummer::
HERA50058602
Beschreibung:
Rack, Cryogenic boxes, HERAfreeze®, Für: HERAfreeze® HFC / HFU, Kryoboxhöhe: 35 mm, Fächer: 9, 142×142×338 mm
VE:
1 * 1 ST
Lieferant:
DEUTSCH NEUMANN
Beschreibung:
Naturgummi.
Lieferant:
Tonbo Biosciences
Beschreibung:
The C17.8 antibody is specific for the 40 kDa (p40) protein subunit shared by the cytokines IL-12 and IL-23. To form IL-12, p40 assembles with a separate 35 kDa protein known as p35, resulting in a 70 kDa functional cytokine. IL-12 is secreted by activated monocytes, macrophages, and dendritic cells, and has been shown to target naïve, resting CD4+ T cells to promote their proliferation and secretion of cytokines. IL-23 contains the p40 subunit in combination with a 19 kDa protein chain, p19; its primary source being activated dendritic cells and other antigen-presenting cells. IL-23 appears to target different cell types than IL-12, acting on memory CD4+ T cells to induce a strong proliferative response and contributing to the generation and expansion of Th17 cells. Like the cytokines themselves, the receptors for IL-12 and IL-23 share one subunit, as well as containing distinct cytokine-specific subunits.
Artikel-Nr:
(REST31661)
Lieferant:
Restek
Hersteller-Artikelnummer::
31661
Lokale Artikelnummer::
REST31661
Beschreibung:
Single-component explosives solutions supports US department of defense base closures and remediation.
VE:
1 * 1 ST
Artikel-Nr:
(PEAK60-3500)
Lieferant:
PEAK SCIENTIFIC INSTRUMENTS
Hersteller-Artikelnummer::
60-3500
Lokale Artikelnummer::
PEAK60-3500
Beschreibung:
The Precision Zero Air generators are designed specifically to supply clean, dry, hydrocarbon-free air to be used as flame support gas for GC at both standard and trace detection limits.
VE:
1 * 1 ST
Artikel-Nr:
(BOSSBS-9047R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9047R-CY7
Lokale Artikelnummer::
BOSSBS-9047R-CY7
Beschreibung:
Voltage-modulated Ca(2+)-activated, monovalent cation channel (VCAM) that mediates a transient membrane depolarization and plays a central role in taste transduction. Monovalent-specific, non-selective cation channel that mediates the transport of Na(+), K(+) and Cs(+) ions equally well. Activated directly by increases in intracellular Ca(2+), but is impermeable to it. Gating is voltage-dependent and displays rapid activation and deactivation kinetics upon channel stimulation even during sustained elevations in Ca(2+). Also activated by a fast intracellular Ca(2+) increase in response to inositol 1,4,5-triphosphate-producing receptor agonists. The channel is blocked by extracellular acidification. External acidification has 2 effects, a fast reversible block of the current and a slower irreversible enhancement of current inactivation. Is a highly temperature-sensitive, heat activated channel showing a steep increase of inward currents at temperatures between 15 and 35 degrees Celsius. Heat activation is due to a shift of the voltage-dependent activation curve to negative potentials. Activated by arachidonic acid in vitro. May be involved in perception of bitter, sweet and umami tastes. May also be involved in sensing semiochemicals.
VE:
1 * 100 µl
Lieferant:
BUCHI
Beschreibung:
Borosilicate glass 3.3.
Artikel-Nr:
(SIAL631299-1G)
Lieferant:
Sigma-Aldrich
Hersteller-Artikelnummer::
631299-1G
Lokale Artikelnummer::
SIAL631299-1G
Beschreibung:
3',5'-Dinitroacetophenon, Sigma-Aldrich®
VE:
1 * 1 g
Artikel-Nr:
(212-6190)
Lieferant:
DWK Life Sciences
Hersteller-Artikelnummer::
868806
Lokale Artikelnummer::
WHEA868806
Beschreibung:
PP.
VE:
1 * 5 ST
Lieferant:
KARTELL
Beschreibung:
Transparent, punched labels for use with wash bottles and plastic or glass reagent bottles.
Preis auf Anfrage
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Dieses Produkt kann nur an eine Lieferadresse versandt werden die über die entsprechende Lizenzen verfügt. Für weitere Hilfe bitte kontaktieren Sie Ihr VWR Vertriebszentrum.
-Additional Documentation May be needed to purchase this item. A VWR representative will contact you if needed.
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