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2-Fluor-4-formylphenylboronsäure
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2-Fluor-4-formylphenylboronsäure
Artikel-Nr:
(BOSSBS-6672R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6672R-A555
Lokale Artikelnummer::
BOSSBS-6672R-A555
Beschreibung:
This potassium channel is controlled by G proteins. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. This receptor plays a crucial role in regulating the heartbeat.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-7508R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-7508R-A680
Lokale Artikelnummer::
BOSSBS-7508R-A680
Beschreibung:
Tmtsp is a novel marker gene for primitive hematopoietic cells and endothelial cells. Tmtsp gene is a newly identified cell-surface molecule with thrombospondin domain. Tmtsp antibody would serve as a valuable tool for the analysis of both embryonic and adult hematopoiesis, as well as for vascular biology.Cellular localisation: Isoform 1: Membrane; Single-pass type I membrane protein, Isoform 2: Membrane; Single-pass type I membrane protein, Isoform 3: Secreted.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11520R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11520R-A350
Lokale Artikelnummer::
BOSSBS-11520R-A350
Beschreibung:
Neuropeptides that play a significant role in the regulation of food intake and sleep-wakefulness, possibly by coordinating the complex behavioral and physiologic responses of these complementary homeostatic functions. A broader role in the homeostatic regulation of energy metabolism, autonomic function, hormonal balance and the regulation of body fluids, is also suggested. Orexin-A binds to both OX1R and OX2R with a high affinity, whereas orexin-B binds only to OX2R with a similar high affinity.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9009R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9009R-A350
Lokale Artikelnummer::
BOSSBS-9009R-A350
Beschreibung:
Transportin 1 is the beta subunit of the karyopherin receptor complex which interacts with nuclear localization signals to target proteins to the nucleus. The karyopherin receptor complex is a heterodimer of an alpha subunit which recognizes the nuclear localization signal and a beta subunit which docks the complex at nucleoporins. Alternate splicing of this gene results in two transcript variants encoding different proteins. In cases of HIV-1 infections, transportin 1 is known to bind and mediate the nuclear import of HIV-1 Rev.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-13041R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13041R-A555
Lokale Artikelnummer::
BOSSBS-13041R-A555
Beschreibung:
Leu-enkephalins compete with and mimic the effects of opiate drugs. They play a role in a number of physiologic functions, including pain perception and responses to stress (By similarity). Dynorphin peptides differentially regulate the kappa opioid receptor. Dynorphin A(1-13) has a typical opiod activity, it is 700 times more potent than Leu-enkephalin (By similarity). Leumorphin has a typical opiod activity and may have anti-apoptotic effect.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-2231R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-2231R-A555
Lokale Artikelnummer::
BOSSBS-2231R-A555
Beschreibung:
Downregulates SLC1A2/EAAT2 promoter activity when expressed ectopically. Activates the nuclear factor kappa-B (NF-kappa-B) transcription factor. Promotes anchorage-independent growth of immortalized melanocytes and astrocytes which is a key component in tumor cell expansion. Promotes lung metastasis and also has an effect on bone and brain metastasis, possibly by enhancing the seeding of tumor cells to the target organ endothelium. Induces chemoresistance.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-2787R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-2787R-A680
Lokale Artikelnummer::
BOSSBS-2787R-A680
Beschreibung:
The proteasome is a multicatalytic proteinase complex which is characterised by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity. This subunit is involved in antigen processing to generate class I binding peptides. Replacement of PSMB6 by PSMB9 increases the capacity of the immunoproteasome to cleave model peptides after hydrophobic and basic residues.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5883R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5883R-A350
Lokale Artikelnummer::
BOSSBS-5883R-A350
Beschreibung:
Scaffold protein that connects plasma membrane proteins with members of the ezrin/moesin/radixin family and thereby helps to link them to the actin cytoskeleton and to regulate their surface expression. Necessary for recycling of internalized ADRB2. Was first known to play a role in the regulation of the activity and subcellular location of SLC9A3. Necessary for cAMP-mediated phosphorylation and inhibition of SLC9A3. May enhance Wnt signaling. May participate in HTR4 targeting to microvilli (By similarity). Interacts with MCC.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-6266R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6266R-A350
Lokale Artikelnummer::
BOSSBS-6266R-A350
Beschreibung:
This protein encoded is a cytoplasmic nonreceptor protein kinase which may function as an intracellular signal transducer in epithelial tissues. Overexpression of this gene in mammary epithelial cells leads to sensitization of the cells to epidermal growth factor and results in a partially transformed phenotype. Expression of this gene has been detected at low levels in some breast tumors but not in normal breast tissue. Its presence in the nucleus appears to be linked to suppression of tumor progression. The encoded protein has been shown to undergo autophosphorylation.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11301R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11301R-A488
Lokale Artikelnummer::
BOSSBS-11301R-A488
Beschreibung:
This gene encodes a member of the insulin-like hormone superfamily. The encoded protein is mainly produced in gonadal tissues. Studies of the mouse counterpart suggest that this gene may be involved in the development of urogenital tract and female fertility. This protein may also act as a hormone to regulate growth and differentiation of gubernaculum, and thus mediating intra-abdominal testicular descent. Mutations in this gene may lead to cryptorchidism. Alternate splicing results in multiple transcript variants. [provided by RefSeq, May 2012].
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-15271R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-15271R-A488
Lokale Artikelnummer::
BOSSBS-15271R-A488
Beschreibung:
Chromosome 7 has been linked to Osteogenesis imperfecta, Pendred syndrome, Lissencephaly, Citrullinemia and Shwachman-Diamond syndrome. The deletion of a portion of the q arm of chromosome 7 is associated with Williams-Beuren syndrome, a condition characterised by mild mental retardation, an unusual comfort and friendliness with strangers and an elfin appearance. Deletions of portions of the q arm of chromosome 7 are also seen in a number of myeloid disorders including cases of acute myelogenous leukemia and myelodysplasia. The C7orf46 gene product has been provisionally designated C7orf46 pending further characterisation.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11374R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11374R-A555
Lokale Artikelnummer::
BOSSBS-11374R-A555
Beschreibung:
The synaptogyrin family of proteins are integral membrane proteins containing four transmembrane regions. Synaptogyrins are tyrosine-phosphorylated proteins with two neuronal (Synaptogyrin-1 and -3) and one ubiquitous (Synaptogyrin-2) isoform. Synaptophysin and synaptogyrin represent the major constituents of synaptic vesicles. Synaptogyrin-1 is associated with presynaptic vesicles in neuronal cells. Synaptogyrin-2, also known as cellugyrin, has a tyrosine phosphorylated C-terminal cytoplasmic tail and is involved in the regulation of membrane traffic in non-neuronal cells. Synaptogyrin-3 is expressed mainly in brain and placenta.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-0741R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0741R-A350
Lokale Artikelnummer::
BOSSBS-0741R-A350
Beschreibung:
May be the important intermediate by which p53/TP53 mediates its role as an inhibitor of cellular proliferation in response to DNA damage. Binds to and inhibits cyclin-dependent kinase activity, preventing phosphorylation of critical cyclin-dependent kinase substrates and blocking cell cycle progression. Functions in the nuclear localization and assembly of cyclin D-CDK4 complex and promotes its kinase activity towards RB1. At higher stoichiometric ratios, inhibits the kinase activity of the cyclin D-CDK4 complex (By similarity).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-6715R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6715R-A555
Lokale Artikelnummer::
BOSSBS-6715R-A555
Beschreibung:
The protein encoded by this gene converts UDP-glucose to UDP-glucuronate and thereby participates in the biosynthesis of glycosaminoglycans such as hyaluronan, chondroitin sulfate, and heparan sulfate. These glycosylated compounds are common components of the extracellular matrix and likely play roles in signal transduction, cell migration, and cancer growth and metastasis. The expression of this gene is up-regulated by transforming growth factor beta and down-regulated by hypoxia. Alternative splicing results in multiple transcript variants.[provided by RefSeq, May 2010].
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5394R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5394R-A555
Lokale Artikelnummer::
BOSSBS-5394R-A555
Beschreibung:
Receptor for IL1A, IL1B and IL1RN. After binding to interleukin-1 associates with the corecptor IL1RAP to form the high affinity interleukin-1 receptor complex which mediates interleukin-1-dependent activation of NF-kappa-B, MAPK and other pathways. Signaling involves the recruitment of adapter molecules such as TOLLIP, MYD88, and IRAK1 or IRAK2 via the respective TIR domains of the receptor/coreceptor subunits. Binds ligands with comparable affinity and binding of antagonist IL1RN prevents association with IL1RAP to form a signaling complex.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11497R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11497R-A647
Lokale Artikelnummer::
BOSSBS-11497R-A647
Beschreibung:
VAX2 is a 290 amino acid homeobox protein that plays a crucial role in development of the eye, particularly in the specification of the ventral optic vesicle and in establishment of a correct dorsoventral pattern. VAX2 acts as a transcription factor with VAX1 to cooperatively regulate retinal differentiation, neuroepithelial cell proliferation and axial polarization in the retina. Together, VAX1 and VAX2 repress transcription of Pax-6, a strong inducer of retinal development. VAX1 and VAX2 localize to the nucleus and contain one homeobox DNA-binding domain each.
VE:
1 * 100 µl
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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