Suche >
2-Fluor-4-methylanisol
Drucken
Sie suchten nach:
57 620 results were found
2-Fluor-4-methylanisol
Artikel-Nr:
(BOSSBS-4958R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-4958R-A555
Lokale Artikelnummer::
BOSSBS-4958R-A555
Beschreibung:
PCGF1 is a component of the Polycomb group (PcG) multiprotein BCOR complex, a complex required to maintain the transcriptionally repressive state of some genes, such as BCL6 and the cyclin-dependent kinase inhibitor, CDKN1A. It represses CDKN1A expression by binding to its promoter, and this repression is dependent on the retinoic acid response element (RARE element). PCGF1 als promotes cell cycle progression and also enhances cell proliferation, thus it may have a positive role in tumor cell growth.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5734R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5734R-A555
Lokale Artikelnummer::
BOSSBS-5734R-A555
Beschreibung:
PCGF1 is a component of the Polycomb group (PcG) multiprotein BCOR complex, a complex required to maintain the transcriptionally repressive state of some genes, such as BCL6 and the cyclin-dependent kinase inhibitor, CDKN1A. It represses CDKN1A expression by binding to its promoter, and this repression is dependent on the retinoic acid response element (RARE element). PCGF1 als promotes cell cycle progression and also enhances cell proliferation, thus it may have a positive role in tumor cell growth.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-13328R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13328R-A750
Lokale Artikelnummer::
BOSSBS-13328R-A750
Beschreibung:
Gemin4 is a component of the SMN core complex which, while in the cytoplasm, plays an essential role in ribonucleoprotein (snRNP) assembly, including the biogenesis, delivery and recycling of snRNPs to the spliceosome. In the nucleus, where SMN is required for pre-mRNA splicing, Gemin4 concentrates next to coiled bodies in subnuclear structures called gems, that are highly enriched in splicosomal snRNPs, and in the nucleolus. Deletion or loss-of-function mutations in the SMN lead to the neurodegenerative disease spinal muscular atrophy (SMA). The human Gemin4 maps to chromosome 17p13.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9909R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9909R-A680
Lokale Artikelnummer::
BOSSBS-9909R-A680
Beschreibung:
GGT6 belongs to the gamma-glutamyltransferase family. GGT is a membrane-bound extracellular enzyme that cleaves gamma-glutamyl peptide bonds in glutathione and other peptides and transfers the gamma-glutamyl moiety to acceptors. GGT is also key to glutathione homeostasis because it provides substrates for glutathione synthesis. GGT6 has very limited amino acid similarity to GGT1 and it's enzymatic activities are currently uncharacterised. GGT assays are of current widespread clinical use to help assess tissue damage.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-15279R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-15279R-A750
Lokale Artikelnummer::
BOSSBS-15279R-A750
Beschreibung:
Chromosome 7 has been linked to Osteogenesis imperfecta, Pendred syndrome, Lissencephaly, Citrullinemia and Shwachman-Diamond syndrome. The deletion of a portion of the q arm of chromosome 7 is associated with Williams-Beuren syndrome, a condition characterised by mild mental retardation, an unusual comfort and friendliness with strangers and an elfin appearance. Deletions of portions of the q arm of chromosome 7 are also seen in a number of myeloid disorders including cases of acute myelogenous leukemia and myelodysplasia. The C7orf64 gene product has been provisionally designated C7orf64 pending further characterisation.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3594R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3594R-A750
Lokale Artikelnummer::
BOSSBS-3594R-A750
Beschreibung:
A novel gene, Genes associated with Retinoid IFN induced Mortality (GRIM) GRIM19 gene was identified. Antisense expression of GRIM19 confers a strong resistance against IFN/RA induced death by reducing the intracellular levels of GRIM19 protein. Overexpression of GRIM19 enhances cell death in response to IFN/RA. GRIM19 is primarily a nuclear protein whose expression is induced by the IFN/RA combination. These data indicate that GRIM19 is a novel cell death regulatory molecule.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-1693R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1693R-A647
Lokale Artikelnummer::
BOSSBS-1693R-A647
Beschreibung:
Calcium-binding protein that interacts with newly synthesized glycoproteins in the endoplasmic reticulum. It may act in assisting protein assembly and/or in the retention within the ER of unassembled protein subunits. It seems to play a major role in the quality control apparatus of the ER by the retention of incorrectly folded proteins. Associated with partial T-cell antigen receptor complexes that escape the ER of immature thymocytes, it may function as a signaling complex regulating thymocyte maturation. Additionally it may play a role in receptor-mediated endocytosis at the synapse.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-2652R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-2652R-A488
Lokale Artikelnummer::
BOSSBS-2652R-A488
Beschreibung:
Sphingosine-1-phosphate (SPP) is a novel lipid messenger with both intracellular and extracellular functions. Intracellularly, it regulates proliferation and survival, and extracellularly, it is a ligand for EDG1 (MIM 601974). Various stimuli increase cellular levels of SPP by activation of sphingosine kinase (SPHK), the enzyme that catalyzes the phosphorylation of sphingosine. Competitive inhibitors of SPHK block formation of SPP and selectively inhibit cellular proliferation induced by a variety of factors, including platelet-derived growth factor (e.g., MIM 173430) and serum.[supplied by OMIM].
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3145R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3145R-A350
Lokale Artikelnummer::
BOSSBS-3145R-A350
Beschreibung:
This gene encodes a member of the O class of winged helix/forkhead transcription factor family. Proteins encoded by this class are regulated by factors involved in growth and differentiation indicating they play a role in these processes. A translocation involving this gene on chromosome X and the homolog of the Drosophila trithorax gene, encoding a DNA binding protein, located on chromosome 11 is associated with leukemia. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2010]
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3396R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3396R-A647
Lokale Artikelnummer::
BOSSBS-3396R-A647
Beschreibung:
This gene encodes a serine/threonine protein kinase that plays an important role in cellular stress response. This kinase activates certain potassium, sodium, and chloride channels, suggesting an involvement in the regulation of processes such as cell survival, neuronal excitability, and renal sodium excretion. High levels of expression of this gene may contribute to conditions such as hypertension and diabetic nephropathy. Several alternatively spliced transcript variants encoding different isoforms have been noted for this gene. [provided by RefSeq, Jan 2009]
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-0806R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0806R-A555
Lokale Artikelnummer::
BOSSBS-0806R-A555
Beschreibung:
Type IV collagen is the major structural component of glomerular basement membranes (GBM), forming a 'chicken-wire' meshwork together with laminins, proteoglycans and entactin/nidogen. Arresten, comprising the C-terminal NC1 domain, inhibits angiogenesis and tumor formation. The C-terminal half is found to possess the anti-angiogenic activity. Specifically inhibits endothelial cell proliferation, migration and tube formation. Inhibits expression of hypoxia-inducible factor 1alpha and ERK1/2 and p38 MAPK activation. Ligand for alpha1/beta1 integrin (By similarity).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-4587R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-4587R-A488
Lokale Artikelnummer::
BOSSBS-4587R-A488
Beschreibung:
Cytokine with a wide variety of biological functions. It is a potent inducer of the acute phase response. Plays an essential role in the final differentiation of B-cells into Ig-secreting cells Involved in lymphocyte and monocyte differentiation. Acts on B-cells, T-cells, hepatocytes, hematopoietic progenitor cells and cells of the CNS. Required for the generation of T(H)17 cells. Also acts as a myokine. It is discharged into the bloodstream after muscle contraction and acts to increase the breakdown of fats and to improve insulin resistance. It induces myeloma and plasmacytoma growth and induces nerve cells differentiation.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5046R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5046R-A350
Lokale Artikelnummer::
BOSSBS-5046R-A350
Beschreibung:
The Cyp46 gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This endoplasmic reticulum protein is expressed exclusively in the brain, where it converts cholesterol to 24S-hydroxycholesterol by adding a hydroxyl group to cholesterol, producing a product that is more soluble than cholesterol and able to be exported from the brain.Cyp46 is also known as 24S-cholesterol hydroxylase.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-0367G-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0367G-A488
Lokale Artikelnummer::
BOSSBS-0367G-A488
Beschreibung:
The complement factor C3 consists of an alpha and a beta chain. C3 is a central factor in the complement cascade. It is central to the alternative pathway that leads to the C3 convertase C3bBb. The classical mannose binding lectin activation pathway leads to the C3 convertase C4b2a. These convertases cleave C3 resulting in C3a and C3b. Further degradation leads to the formation of the alpha chain products C3d, C3g and C3c. C3 is an acute phase protein that is produced by a wide range of tissues, including renal epithelial cells and hepatocytes.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5145R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5145R-A488
Lokale Artikelnummer::
BOSSBS-5145R-A488
Beschreibung:
This gene is a member of the natriuretic peptide family and encodes a secreted protein which functions as a cardiac hormone. The protein undergoes two cleavage events, one within the cell and a second after secretion into the blood. The protein's biological actions include natriuresis, diuresis, vasorelaxation, inhibition of renin and aldosterone secretion, and a key role in cardiovascular homeostasis. A high concentration of this protein in the bloodstream is indicative of heart failure. Mutations in this gene have been associated with postmenopausal osteoporosis.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5032R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5032R-A555
Lokale Artikelnummer::
BOSSBS-5032R-A555
Beschreibung:
Agpat2 is a member of the 1-acylglycerol-3-phosphate O-acyltransferase family. It is located within the endoplasmic reticulum membrane and converts lysophosphatidic acid to phosphatidic acid, the second step in de novo phospholipid biosynthesis. Mutations in its have been associated with congenital generalized lipodystrophy (CGL), or Berardinelli-Seip syndrome, a disease characterized by a near absence of adipose tissue and severe insulin resistance. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
VE:
1 * 100 µl
Preis auf Anfrage
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Dieses Produkt kann nur an eine Lieferadresse versandt werden die über die entsprechende Lizenzen verfügt. Für weitere Hilfe bitte kontaktieren Sie Ihr VWR Vertriebszentrum.
-Additional Documentation May be needed to purchase this item. A VWR representative will contact you if needed.
Dieses Produkt wurde von Ihrer Organisation gesperrt. Bitte kontaktieren Sie Ihren Einkauf für weitere Informationen.
Dieses Produkt ist Ersatz für den von Ihnen gewünschten Artikel.
Dieses Produkt ist nicht mehr verfügbar. Bitte kontaktieren Sie den VWR Kundenservice.
|
|||||||||
Listenansicht
