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1,2-Propylendiamin
Artikel-Nr:
(BOSSBS-4181R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-4181R-A350
Lokale Artikelnummer::
BOSSBS-4181R-A350
Beschreibung:
This gene encodes the small subunit of a p53-inducible ribonucleotide reductase. This heterotetrameric enzyme catalyzes the conversion of ribonucleoside diphosphates to deoxyribonucleoside diphosphates. The product of this reaction is necessary for DNA synthesis. Mutations in this gene have been associated with autosomal recessive mitochondrial DNA depletion syndrome, autosomal dominant progressive external ophthalmoplegia-5, and mitochondrial neurogastrointestinal encephalopathy. Alternatively spliced transcript variants have been described.[provided by RefSeq, Feb 2010].
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-7763R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-7763R-A350
Lokale Artikelnummer::
BOSSBS-7763R-A350
Beschreibung:
Regulates RHOA activity, and plays a role in cytoskeleton remodeling. Necessary for normal completion of cytokinesis. Plays a role in maintaining normal diacylglycerol levels in the Golgi apparatus. Binds phosphatidyl inositol phosphates (in vitro). May catalyze the transfer of phosphatidylinositol and phosphatidylcholine between membranes (By similarity). Necessary for maintaining the normal structure of the endoplasmic reticulum and the Golgi apparatus. Required for protein export from the endoplasmic reticulum and the Golgi. Binds calcium ions.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-2361R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-2361R-A680
Lokale Artikelnummer::
BOSSBS-2361R-A680
Beschreibung:
The protein encoded by this gene belongs to the CDK subfamily of the Ser/Thr protein kinase family. The CDK subfamily members are highly similar to the gene products of S. cerevisiae cdc28, and S. pombe cdc2, and are known to be essential for cell cycle progression. This kinase has been shown to play a role in cellular proliferation and its function is limited to cell cycle G2-M phase. Multiple transcript variants encoding different isoforms have been found for this gene.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-7551R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-7551R-A350
Lokale Artikelnummer::
BOSSBS-7551R-A350
Beschreibung:
ABIN-3 is a member of the A20-binding inhibitor of NF-kappaB activation (ABIN) protein family. Similar to the previously characterized human ABINs (ABIN-1 and ABIN-2), ABIN-3 can bind to A20 and inhibit NF-kappaB activation. In contrast, mouse ABIN-3 is incapable of inhibiting NF-kappaB activation by proinflammatory stimuli because the protein lacks a complete ABIN homology domain, which is required for the funcitonal activity of human ABIN-3.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3882R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3882R-A555
Lokale Artikelnummer::
BOSSBS-3882R-A555
Beschreibung:
This gene product belongs to the family of glutathione peroxidase, which functions in the detoxification of hydrogen peroxide. It contains a selenocysteine (Sec) residue at its active site. The selenocysteine is encoded by the UGA codon, which normally signals translation termination. The 3' UTR of Sec-containing genes have a common stem-loop structure, the sec insertion sequence (SECIS), which is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. [provided by RefSeq].
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-8027R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-8027R-A555
Lokale Artikelnummer::
BOSSBS-8027R-A555
Beschreibung:
The protein encoded by this gene is an auxiliary subunit of the ionotropic glutamate receptor of the AMPA subtype. AMPA receptors mediate fast synaptic neurotransmission in the central nervous system. This protein has been reported to interact with the Type I AMPA receptor regulatory protein isoform gamma-8 to control assembly of hippocampal AMPA receptor complexes, thereby modulating receptor gating and pharmacology. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2012].
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-1145R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1145R-A488
Lokale Artikelnummer::
BOSSBS-1145R-A488
Beschreibung:
This gene encodes a member of the human ARF gene family, which is part of the RAS superfamily. The ARF genes encode small guanine nucleotide-binding proteins that stimulate the ADP-ribosyltransferase activity of cholera toxin and play a role in vesicular trafficking and as activators of phospholipase D. The product of this gene is localized to the plasma membrane, and regulates vesicular trafficking, remodelling of membrane lipids, and signaling pathways that lead to actin remodeling. A pseudogene of this gene is located on chromosome 7.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-0135R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0135R-A488
Lokale Artikelnummer::
BOSSBS-0135R-A488
Beschreibung:
Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co-chaperones that modulate its substrate recognition, ATPase cycle and chaperone function.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-12191R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12191R-A750
Lokale Artikelnummer::
BOSSBS-12191R-A750
Beschreibung:
DZIP3 is a 1208 amino acid protein that localizes to the cytoplasm and contains one RING-type zinc finger. Expressed in a variety of tissues with highest expression in heart, skeletal muscle and kidney, DZIP3 functions as an E3 ubiquitin-protein ligase that accepts ubiquitin from an E2 ubiquitin-conjugating enzyme, thereby playing a role in Signalling events throughout the cell. Multiple isoforms of DZIP3 exist due to alternative splicing events.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-1444R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1444R-A555
Lokale Artikelnummer::
BOSSBS-1444R-A555
Beschreibung:
Key component of innate and adaptive immunity. TLRs (Toll-like receptors) control host immune response against pathogens through recognition of molecular patterns specific to microorganisms. TLR3 is a nucleotide-sensing TLR which is activated by double-stranded RNA, a sign of viral infection. Acts via the adapter TRIF/TICAM1, leading to NF-kappa-B activation, IRF3 nuclear translocation, cytokine secretion and the inflammatory response (By similarity).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-4140R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-4140R-A555
Lokale Artikelnummer::
BOSSBS-4140R-A555
Beschreibung:
This gene product appears to function as a negative regulator of the ras signal transduction pathway. Mutations in this gene have been linked to neurofibromatosis type 1, juvenile myelomonocytic leukemia and Watson syndrome. The mRNA for this gene is subject to RNA editing (CGA>UGA->Arg1306Term) resulting in premature translation termination. Alternatively spliced transcript variants encoding different isoforms have also been described for this gene. [provided by RefSeq, Jul 2008].
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-6800R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6800R-A647
Lokale Artikelnummer::
BOSSBS-6800R-A647
Beschreibung:
Component of the N-oligosaccharyl transferase enzyme which catalyzes the transfer of a high mannose oligosaccharide from a lipid-linked oligosaccharide donor to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). Loss of the DAD1 protein triggers apoptosis.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-2928R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-2928R-A647
Lokale Artikelnummer::
BOSSBS-2928R-A647
Beschreibung:
The protein encoded by this gene contains a PDZ domain and a LIM domain, indicating that it may be involved in cytoskeletal assembly. In support of this, the encoded protein has been shown to bind the spectrin-like repeats of alpha-actinin-2 and to colocalize with alpha-actinin-2 at the Z lines of skeletal muscle. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. Aberrant alternative splicing of this gene may play a role in myotonic dystrophy.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5682R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5682R-A647
Lokale Artikelnummer::
BOSSBS-5682R-A647
Beschreibung:
Rsk1 is a member of a family of 90kDa ribosomal protein S6 kinases, which includes Rsk1, Rsk2 and Rsk3. These are broadly expressed serine/threonine protein kinases activated in response to mitogenic stimuli, including extracellular signal regulated protein kinases Erk1 and Erk2. Rsk1 is activated by MAPK in vitro and in vivo via phosphorylation. Active Rsks appear to play a major role in transcriptional regulation by translocating to the nucleus and phosphorylating c Fos and CREB.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9214R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9214R-A488
Lokale Artikelnummer::
BOSSBS-9214R-A488
Beschreibung:
Metastasis of a primary tumor to a distant site is determined through signaling cascades that break down interactions between the cell and extracellular matrix proteins. Among the proteins mediating metastasis are serine prote-ases, such as neutrophil elastase.SCCA is transcribed by two nearly identical genes (SCCA1 and SCCA2), and is mainly produced as SCCA1. The human SCCA1 gene encodes a 390 amino acid protein that was originally isolated from a metastatic cervical squamous cell carcinoma.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3809R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3809R-A555
Lokale Artikelnummer::
BOSSBS-3809R-A555
Beschreibung:
In the presence of inorganic orthophosphate, the platelet-derived endothelial growth factor (PD-ECGF) thymidine phosphorylase (TP) (gliostatin) catalyses the reversible phospholytic cleavage of thymidine and deoxyuridine to their corresponding bases and 2-deoxyribose-1-phosphate. It is both chemotactic and mitogenic for endothelial cells and a non-heparin binding angiogenic factor present in platelets. It is also involved in transformation of fluoropyrimidines, cytotoxic agents used in the treatment of a variety of malignancies, into active cytotoxic metabolites.
VE:
1 * 100 µl
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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