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2-Fluor-4-methylphenylborons\u00E4ure
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2-Fluor-4-methylphenylborons\u00E4ure
Artikel-Nr:
(BOSSBS-6719R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6719R-A555
Lokale Artikelnummer::
BOSSBS-6719R-A555
Beschreibung:
Regulates voltage-gated potassium channels assembled from KCNA1, KCNA4 and KCNAB1. It slows down channel inactivation by precluding channel closure mediated by the KCNAB1 subunit. Ligand for ADAM22 that positively regulates synaptic transmission mediated by AMPA-type glutamate receptors (By similarity). Plays a role in suppressing the production of MMP1/3 through the phosphatidylinositol 3-kinase/ERK pathway. May play a role in the control of neuroblastoma cell survival.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-6734R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6734R-A647
Lokale Artikelnummer::
BOSSBS-6734R-A647
Beschreibung:
SERBP1 (Plasminogen activator inhibitor 1 RNA-binding protein) may play a role in the regulation of mRNA stability. SERBP1 binds to the 3’-most 134 nt of the SERPINE1/PAI1 mRNA, a region which confers cyclic nucleotide regulation of message decay. SERBP1 interacts with CHD3 and is localized in cytoplasmic and nuclear. It is expressed at high level in the heart, skeletal muscle and kidney, and at low levels in placenta, liver and brain.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-2081R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-2081R-A647
Lokale Artikelnummer::
BOSSBS-2081R-A647
Beschreibung:
Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. It is potent pyrogen causing fever by direct action or by stimulation of interleukin-1 secretion and is implicated in the induction of cachexia, Under certain conditions it can stimulate cell proliferation and induce cell differentiation. The TNF intracellular domain (ICD) form induces IL12 production in dendritic cells.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9450R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9450R-A350
Lokale Artikelnummer::
BOSSBS-9450R-A350
Beschreibung:
Cytidine is a nucleoside formed by a cytosine attached to a ribose ring via a beta-N1-glycosidic bond. DNA is methylated on cytidines by DNA methylases (DNMTs)to generate 5-methylcytidine (5-mC), a potent epigenetics marker and regulator of gene expression. The reverse reaction (cytidine demethylation) starts with its oxidation to hydroxymethyl- (5-hmC), formyl- (5-fC), and carboxy- (5-caC) cytidine. Several enzymes, including the Tet family of proteins have been implicated in cytidine demethylation.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-7608R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-7608R-A680
Lokale Artikelnummer::
BOSSBS-7608R-A680
Beschreibung:
Dual-specificity phosphatase involved in DNA damage response. Essential regulator of the G2 DNA damage checkpoint: following DNA damage, translocates to the nucleus and dephosphorylates FZR1/CDH1, a key activator of the anaphase promoting complex/cyclosome (APC/C). Dephosphorylates SIRT2 around early anaphase. Dephosphorylation of FZR1/CDH1 activates the APC/C, leading to the ubiquitination of PLK1, preventing entry into mitosis. Preferentially dephosphorylates proteins modified by proline-directed kinases.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-4181R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-4181R-A647
Lokale Artikelnummer::
BOSSBS-4181R-A647
Beschreibung:
This gene encodes the small subunit of a p53-inducible ribonucleotide reductase. This heterotetrameric enzyme catalyzes the conversion of ribonucleoside diphosphates to deoxyribonucleoside diphosphates. The product of this reaction is necessary for DNA synthesis. Mutations in this gene have been associated with autosomal recessive mitochondrial DNA depletion syndrome, autosomal dominant progressive external ophthalmoplegia-5, and mitochondrial neurogastrointestinal encephalopathy. Alternatively spliced transcript variants have been described.[provided by RefSeq, Feb 2010].
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11874R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11874R-A647
Lokale Artikelnummer::
BOSSBS-11874R-A647
Beschreibung:
Transcriptional cofactor that restricts GATA6 function by inhibiting DNA-binding, resulting in repression of GATA6 transcriptional activation of downstream target genes. Represses GATA6-mediated trans activation of lung- and cardiac tissue-specific promoters. Inhibits DNA-binding by GATA4 and GATA1 to the cTNC promoter (By similarity). Plays a critical role in the development of cardiac hypertrophy via activation of calcineurin/nuclear factor of activated T cells signaling pathway.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-4917R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-4917R-A488
Lokale Artikelnummer::
BOSSBS-4917R-A488
Beschreibung:
Osteocalcin belongs to the osteocalcin/matrix Gla protein family and constitutes 1 to 2% of the total bone protein. It is a 49 amino acid single chain vitamin K dependent protein, made by osteoblasts, and is a major component of the noncollagenous bone matrix. Post translational modification by a vitamin K dependent carboxylase produces three gamma carboxyglutamic acid residues at positions 17, 21 and 24, giving it a high affinity for calcium. It also binds strongly to apatite.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-10128R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-10128R-A647
Lokale Artikelnummer::
BOSSBS-10128R-A647
Beschreibung:
Linker for activation of T cells (LAT) is an integral membrane protein (36 to 38 kD), which plays an important role in linking engagement of the TCR to the biochemical events of T cell activation. LAT antibody stains thymus and peripheral lymphoid tissues such as T cell areas in lymph nodes and spleen. LAT is expressed in T lymphocytes in interstitial spaces, platelets and megakaryocytes. LAT is not expressed in B cells, macrophages, plasma cells, monocytes, epithelial histiocytes and dendritic cells.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-6901R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6901R-A647
Lokale Artikelnummer::
BOSSBS-6901R-A647
Beschreibung:
Component of the CENPA-NAC (nucleosome-associated) complex, a complex that plays a central role in assembly of kinetochore proteins, mitotic progression and chromosome segregation. The CENPA-NAC complex recruits the CENPA-CAD (nucleosome distal) complex and may be involved in incorporation of newly synthesized CENPA into centromeres. CENP-T is one of the basic inner kinetochore proteins with most further proteins binding downstream, suggesting a fundamental role of CENP-T in kinetochore function.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9450R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9450R-A647
Lokale Artikelnummer::
BOSSBS-9450R-A647
Beschreibung:
Cytidine is a nucleoside formed by a cytosine attached to a ribose ring via a beta-N1-glycosidic bond. DNA is methylated on cytidines by DNA methylases (DNMTs)to generate 5-methylcytidine (5-mC), a potent epigenetics marker and regulator of gene expression. The reverse reaction (cytidine demethylation) starts with its oxidation to hydroxymethyl- (5-hmC), formyl- (5-fC), and carboxy- (5-caC) cytidine. Several enzymes, including the Tet family of proteins have been implicated in cytidine demethylation.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-6338R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6338R-A350
Lokale Artikelnummer::
BOSSBS-6338R-A350
Beschreibung:
This gene encodes a lipid-binding protein belonging to the apolipoprotein gene family. The protein is thought to play a role in lipid metabolism. Polymorphisms in this gene may influence circulating lipid levels and may be associated with coronary artery disease risk. This gene is present in a cluster with other related apolipoprotein genes on chromosome 19. Naturally occurring read-through transcription exists between this gene and the neighboring downstream apolipoprotein C-II (APOC2) gene.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-0538R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0538R-A350
Lokale Artikelnummer::
BOSSBS-0538R-A350
Beschreibung:
This gene is imprinted, with preferential expression of the maternal allele. The encoded protein is a tight-binding, strong inhibitor of several G1 cyclin/Cdk complexes and a negative regulator of cell proliferation. Mutations in this gene are implicated in sporadic cancers and Beckwith-Wiedemann syndorome, suggesting that this gene is a tumor suppressor candidate. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Oct 2010].
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-7697R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-7697R-A647
Lokale Artikelnummer::
BOSSBS-7697R-A647
Beschreibung:
Chromatin reader that specifically recognizes and binds histone H3.3 trimethylated at 'Lys-36' (H3.3K36me3) and regulates RNA polymerase II elongation. Does not bind other histone H3 subtypes (H3.1 or H3.2) (By similarity). Colocalizes with highly expressed genes and functions as a transcription corepressor by modulating RNA polymerase II at the elongation stage. Acts as a tumor-suppressor by repressing a transcriptional program essential for tumor cell growth.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-7519R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-7519R-A680
Lokale Artikelnummer::
BOSSBS-7519R-A680
Beschreibung:
Cell surface receptor for PLXNB1, PLXNB2, PLXNB3 and PLXND1 that plays an important role in cell-cell signaling. Plays a role in priming antigen-specific T-cells, promotes differentiation of Th1 T-helper cells, and thereby contributes to adaptive immunity. Promotes phosphorylation of TIMD2. Inhibits angiogenesis. Promotes axon growth cone collapse. Inhibits axonal extension by providing local signals to specify territories inaccessible for growing axons (By similarity).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-6672R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6672R-A488
Lokale Artikelnummer::
BOSSBS-6672R-A488
Beschreibung:
This potassium channel is controlled by G proteins. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. This receptor plays a crucial role in regulating the heartbeat.
VE:
1 * 100 µl
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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