2-Fluor-4-methylphenylborons\u00E4ure
Artikel-Nr:
(BOSSBS-9298R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9298R-A555
Lokale Artikelnummer::
BOSSBS-9298R-A555
Beschreibung:
BCL7B shows high homology to the BCL7A protein, which is known to be directly involved in a complex chromosomal translocation in Burkitt lymphoma cell lines. The specific function of BCL7B has not yet been determined. However, it may play a role in lung tumor development or progression. The BCL7B gene is located at a chromosomal region commonly deleted in the congenital disorder, Williams syndrome.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-6459R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6459R-A750
Lokale Artikelnummer::
BOSSBS-6459R-A750
Beschreibung:
Binds pre-mRNA and nucleates the assembly of 40S hnRNP particles. Single HNRNPC tetramers bind 230-240 nucleotides. Trimers of HNRNPC tetramers bind 700 nucleotides. May play a role in the early steps of spliceosome assembly and pre-mRNA splicing. Interacts with poly-U tracts in the 3'-UTR or 5'-UTR of mRNA and modulates the stability and the level of translation of bound mRNA molecules.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-8929R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-8929R-A488
Lokale Artikelnummer::
BOSSBS-8929R-A488
Beschreibung:
Cyclin E is a regulatory subunit of Cdk2 and controls G1 / S transition during the mammalian cell cycle. Multiple isoforms of Cyclin E are only expressed in tumors but not in normal tissue, suggesting a post transcriptional regulation of Cyclin E. In vitro analyses indicated that these truncated variant isoforms of Cyclin E are able to phosphorylate histone H1. Alterations in the Cyclin E protein have been implicated as indicators of worse prognosis in various cancers.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9883R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9883R-A680
Lokale Artikelnummer::
BOSSBS-9883R-A680
Beschreibung:
Zeta-globin is an alpha-like hemoglobin. The zeta-globin polypeptide is synthesised in the yolk sac of the early embryo, while alpha-globin is produced throughout fetal and adult life. The zeta-globin gene is a member of the human alpha-globin gene cluster that includes five functional genes and two pseudogenes. The order of genes is: 5' - zeta - pseudozeta - mu - pseudoalpha-1 - alpha-2 -alpha-1 - theta1 - 3'.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11250R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11250R-A555
Lokale Artikelnummer::
BOSSBS-11250R-A555
Beschreibung:
Receptor involved in the costimulatory signal essential for T-lymphocyte proliferation and interleukin-2 production, by binding CD28 or CTLA-4. May play a critical role in the early events of T-cell activation and costimulation of naive T-cells, such as deciding between immunity and anergy that is made by T-cells within 24 hours after activation. Isoform 2 interferes with the formation of CD86 clusters, and thus acts as a negative regulator of T-cell activation.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9220R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9220R-A680
Lokale Artikelnummer::
BOSSBS-9220R-A680
Beschreibung:
Chemorepulsive axon guidance protein required for the development of spinal cord and forebrain commissures. Acts as a chemorepulsive guidance protein for commissural axons during development. Able to inhibit or repel neurite outgrowth from dorsal spinal cord. Inhibits the stabilisation of cytosolic beta-catenin (CTNNB1) via its interaction with LRP6, thereby acting as an antagonist of Wnt signaling pathway.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9166R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9166R-A647
Lokale Artikelnummer::
BOSSBS-9166R-A647
Beschreibung:
The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc binding domains, a RING, a B box type 1 and a B box type 2, and a coiled coil region. The protein localizes to cytoplasmic bodies. Its function has not been identified. Alternative splicing of this gene generates three transcript variants, named alpha, beta and gamma.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-1696R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1696R-A647
Lokale Artikelnummer::
BOSSBS-1696R-A647
Beschreibung:
Receptor for the cytotoxic ligand TNFSF10/TRAIL. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. Promotes the activation of NF-kappa-B. Essential for ER stress-induced apoptosis (By similarity).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-6259R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6259R-A488
Lokale Artikelnummer::
BOSSBS-6259R-A488
Beschreibung:
Dual-specificity kinase which possesses both serine/threonine and tyrosine kinase activities. Enhances the transcriptional activity of TCF1/HNF1A and FOXO1. Inhibits epithelial cell migration. Mediates colon carcinoma cell survival in mitogen-poor environments. Inhibits the SHH and WNT1 pathways, thereby enhancing adipogenesis. In addition, promotes expression of the gluconeogenic enzyme glucose-6-phosphatase (G6PC).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-13675R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13675R-A647
Lokale Artikelnummer::
BOSSBS-13675R-A647
Beschreibung:
B cell adaptor for phosphoinositide 3-kinase (BCAP) is a tyrosine kinase substrate that bridges B cell receptor (BCR) associated kinases to the PIK3 pathway. Syk, Btk or Lyn-dependent tyrosine phosphorylation of BCAP, provides binding sites for the p85 subunit of PIK3. BCAP mRNA is present in mouse spleen, thymus, liver, lung, macrophage and B cell lines. Human BCAP maps to chromosome 10q24.2.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-4652R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-4652R-A350
Lokale Artikelnummer::
BOSSBS-4652R-A350
Beschreibung:
Receptor for thymic stromal lymphopoietin (TSLP). Forms a functional complex with TSLP and IL7R which is capable of stimulating cell proliferation through activation of STAT3 and STAT5. Also activates JAK2 (By similarity). Implicated in the development of the hematopoietic system.Tissue specificity: Expressed in heart, skeletal muscle, kidney and adult and fetal liver. Primarily expressed in dendrites and monocytes. Weakly expressed in T-cells.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-15568R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-15568R-A750
Lokale Artikelnummer::
BOSSBS-15568R-A750
Beschreibung:
This gene expresses a paternally imprinted antisense transcript of the insulin-like growth factor 2 gene. The transcript is overexpressed in Wilms' tumor. This gene is predicted to be non-coding because the predicted protein is not conserved in any other species and the majority of transcripts would be candidates for non-sense mediated decay (NMD) if a protein were expressed. Alternative splicing results in multiple transcript variants.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3502R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3502R-A750
Lokale Artikelnummer::
BOSSBS-3502R-A750
Beschreibung:
Synapsin II is a member of the synapsin gene family. Synapsins are neuronal phosphoproteins which associate with the cytoplasmic surface of synaptic vesicles. Family members are characterised by common protein domains, and they are implicated in synaptogenesis and the modulation of neurotransmitter release, suggesting a potential role in several neuropsychiatric diseases. This member of the synapsin family is a neuron-specific phosphoprotein that selectively binds to small synaptic vesicles in the presynaptic nerve terminal.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9046R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9046R-A350
Lokale Artikelnummer::
BOSSBS-9046R-A350
Beschreibung:
The product of this gene belongs to the family of transient receptor potential (TRP) channels. TRP channels are cation-selective channels important for cellular calcium signaling and homeostasis. The protein encoded by this gene mediates calcium entry, and this entry is potentiated by calcium store depletion. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008].
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-6380R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6380R-A555
Lokale Artikelnummer::
BOSSBS-6380R-A555
Beschreibung:
ERCC6L belongs to the SNF2 ATPase family and acts as an essential component of the spindle assembly checkpoint. It contributes to the mitotic checkpoint by recruiting MAD2 to kinetochores and monitoring tension on centromeric chromatin. It acts as a tension sensor that associates with catenated DNA which is stretched under tension until it is resolved during anaphase. ERCC6L may also play a role in the teratogenic action of alcohol.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3509R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3509R-A750
Lokale Artikelnummer::
BOSSBS-3509R-A750
Beschreibung:
Recruited by REST to neuronal genes that contain RE-1 elements, leading to neuronal gene silencing in non-neuronal cells (By similarity). Preferentially catalyses the dephosphorylation of 'Ser-5' within the tandem 7 residue repeats in the C-terminal domain (CTD) of the largest RNA polymerase II subunit POLR2A. Negatively regulates RNA polymerase II transcription, possibly by controlling the transition from initiation/capping to processive transcript elongation.
VE:
1 * 100 µl
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