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2-Fluor-4-methylphenylborons\u00E4ure
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2-Fluor-4-methylphenylborons\u00E4ure
Artikel-Nr:
(BOSSBS-11286R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11286R-A555
Lokale Artikelnummer::
BOSSBS-11286R-A555
Beschreibung:
Lipocalin-1 is a secretory protein that is highly expressed in fluids covering epithelial surfaces such as tears and respiratory secretions. This major lipid-binding protein in tears is also called tear lipocalin (TL) and von Ebner’s gland protein (VEG), as it is also a major secretion of these lingual salivary glands. In addition to lacrimal glands and lingual glands, Lipocalin-1 is secreted by nasal mucosal glands, secretory glands of the tracheobronchial tract, sweat glands, mammary glands, adrenal gland, prostate, thymus, testis and corticotrophs of the pituitary gland. Specifically, Lipocalin-1 functions to stabilize the lipid film of human tear fluid by removing harmful lipids from the human corneal surface and delivering them to the aqueous phase of tears. Lipocalin-1 may also function as a transporter of hydrophobic molecules such as bitter substances on the tongue.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11551R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11551R-A350
Lokale Artikelnummer::
BOSSBS-11551R-A350
Beschreibung:
Emx1 and Emx2 are human homologs to the Drosophila developmental genes empty spiracles expressed in anterior body regions during early Drosophila embryogenesis. Emx1 and Emx2 are homeobox proteins expressed in the developing vertebrate brain. Emx2 is expressed in the dorsal telencephalon and small diencephalic regions, while Emx1 expression is exclusively confined to pyramidal neurons of the dorsal telencephalon. In the embryonic brain, Emx1 is expressed in both proliferating and differentiating neurons while Emx2 is expressed only in proliferating neurons. OTX1 and OTX2 are human homologs of the Drosophila developmental genes orthodenticle. In development, the sequence of expression begins with OTX2 at day ten post coitum followed by OTX1, Emx2 and finally Emx1. The genes encoding human Emx1 and Emx2 map to chromosomes 2p13.2 and 10q26.11, respectively.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-13393R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13393R-A555
Lokale Artikelnummer::
BOSSBS-13393R-A555
Beschreibung:
The fidelity of protein synthesis requires efficient discrimination of amino acid substrates by aminoacyl-tRNA synthetases. Aminoacyl-tRNA synthetases function to catalyze the aminoacylation of tRNAs by their corresponding amino acids, thus linking amino acids with tRNA-contained nucleotide triplets. ProRS (Prolyl-tRNA synthetase), also known as EPRS, EARS, PARS, QARS, QPRS, PIG32 or GLUPRORS, is a 1,512 amino acid protein that contains three WHEP-TRS domains and belongs to both the class-I and class-II aminoacyl-tRNA synthetase family. Functioning as a component of the multisynthase complex, ProRS uses ATP to catalyze the conversion of L-glutamate and tRNA(Glu) to L-glutamyl-tRNA(Glu), as well as the conversion of L-proline and tRNA(Pro) to L-prolyl-tRNA(Pro).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9481R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9481R-A488
Lokale Artikelnummer::
BOSSBS-9481R-A488
Beschreibung:
REEP5 is a 189 amino acid multi-pass membrane protein. Thought to promote the functional cell surface expression of olfactory receptors, REEP5 belongs to the DP1 family and is encoded by a gene that maps to chromosome 5. With 181 million base pairs encoding around 1,000 genes, chromosome 5 is about 6% of human genomic DNA. Chromosome 5 is associated with Cockayne syndrome through the ERCC8 gene and familial adenomatous polyposis through the adenomatous polyposis coli (APC) tumor suppressor gene. Treacher Collins syndrome is also chromosome 5 associated and is caused by insertions or deletions within the TCOF1 gene. Deletion of the p arm of chromosome 5 leads to Cri du chat syndrome. Deletion of 5q or chromosome 5 altogether is common in therapy-related acute myelogenous leukemias and myelodysplastic syndrome.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11924R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11924R-A647
Lokale Artikelnummer::
BOSSBS-11924R-A647
Beschreibung:
The protein tyrosine phosphatase (PTP) family of proteins are signaling molecules that regulate processes such as cell growth, cell differentiation, oncogenic transformation and the mitotic cycle. PCPTP1, also known as PTPRR (Receptor-type tyrosine-protein phosphatase R), ECPTP, PTPBR7 or PTPRQ, is a 657 amino acid protein that functions to sequester inactive mitogen-activated protein kinases (MAPKs) to the cytoplasm. Expressed primarily in the brain with weaker expression in other parts of the body, PCPTP1 is a receptor-like molecule that is able to dephosphorylate MAPKs, thereby rendering them inactive. Three isoforms of PCPTP1 exist and are designated alpha, beta and gamma. The alpha form is localized to the cell membrane, while the beta and gamma forms are localized to the perinuclear areas within the cytoplasm.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9138R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9138R-A680
Lokale Artikelnummer::
BOSSBS-9138R-A680
Beschreibung:
Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. ZSWIM3 (Zinc finger SWIM domain-containing protein 3) is a 696 amino acid protein that contains one SWIM-type zinc finger. SWIM domains are found in a variety of eukaryotic and prokaryotic proteins and are thought to be critical for certain ubiquitination reactions. The gene encoding ZSWIM3 maps to human chromosome 20, which contains nearly 63 million bases that encode over 600 genes, some of which are associated with Creutzfeldt-Jakob disease, amyotrophic lateral sclerosis, spinal muscular atrophy, ring chromosome 20 epilepsy syndrome and Alagille syndrome.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9581R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9581R-A750
Lokale Artikelnummer::
BOSSBS-9581R-A750
Beschreibung:
Component of the LUBAC complex which conjugates linear polyubiquitin chains in a head-to-tail manner to substrates and plays a key role in NF-kappa-B activation and regulation of inflammation. LUBAC conjugates linear polyubiquitin to IKBKG and RIPK1 and is involved in activation of the canonical NF-kappa-B and the JNK Signalling pathways. Linear ubiquitination mediated by the LUBAC complex interferes with TNF-induced cell death and thereby prevents inflammation. LUBAC is proposed to be recruited to the TNF-R1 Signalling complex (TNF-RSC) following polyubiquitination of TNF-RSC components by BIRC2 and/or BIRC3 and to conjugate linear polyubiquitin to IKBKG and possibly other components contributing to the stability of the complex. Together with FAM105B/otulin, the LUBAC complex regulates the canonical Wnt Signalling during angiogenesis.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11712R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11712R-A680
Lokale Artikelnummer::
BOSSBS-11712R-A680
Beschreibung:
The charged multivesicular body proteins, commonly designated CHMPs, belong to the vacuolar sorting protein family and function as chromatin-modifying proteins. CHMP1-6 are all components of ESCRT (endosomal sorting complex required for transport) I, II or III complexes. These complexes are crucial for sorting endosomal articles into multivesicular bodies (MVBs), and are also required for the formation of these bodies. CHMP2B, also known as CHMP2.5 or vacuolar protein-sorting-associated protein 2-2, is a 213 amino acid cytosolic protein. Widely expressed in brain, heart, skeletal muscle, small intestine, pancreas, lung, placenta and leukocytes, CHMP2B associates directly with CHMP2A and vps4 for the disassembly of the ESCRT-III complex. Defects in the gene encoding CHMP2B have been shown to cause chromosome 3-linked frontotemporal dementia (FTD3).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-12904R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12904R-A647
Lokale Artikelnummer::
BOSSBS-12904R-A647
Beschreibung:
The ABL1 protooncogene encodes a cytoplasmic and nuclear protein tyrosine kinase that has been implicated in processes of cell differentiation, cell division, cell adhesion, and stress response. Activity of c-Abl protein is negatively regulated by its SH3 domain, and deletion of the SH3 domain turns ABL1 into an oncogene. The t(9;22) translocation results in the head-to-tail fusion of the BCR (MIM:151410) and ABL1 genes present in many cases of chronic myelogeneous leukemia. The DNA-binding activity of the ubiquitously expressed ABL1 tyrosine kinase is regulated by CDC2-mediated phosphorylation, suggesting a cell cycle function for ABL1. The ABL1 gene is expressed as either a 6- or 7-kb mRNA transcript, with alternatively spliced first exons spliced to the common exons 2-11. [provided by RefSeq].
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11924R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11924R-A680
Lokale Artikelnummer::
BOSSBS-11924R-A680
Beschreibung:
The protein tyrosine phosphatase (PTP) family of proteins are Signalling molecules that regulate processes such as cell growth, cell differentiation, oncogenic transformation and the mitotic cycle. PCPTP1, also known as PTPRR (Receptor-type tyrosine-protein phosphatase R), ECPTP, PTPBR7 or PTPRQ, is a 657 amino acid protein that functions to sequester inactive mitogen-activated protein kinases (MAPKs) to the cytoplasm. Expressed primarily in the brain with weaker expression in other parts of the body, PCPTP1 is a receptor-like molecule that is able to dephosphorylate MAPKs, thereby rendering them inactive. Three isoforms of PCPTP1 exist and are designated alpha, beta and gamma. The alpha form is localised to the cell membrane, while the beta and gamma forms are localised to the perinuclear areas within the cytoplasm.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-1083R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1083R-A680
Lokale Artikelnummer::
BOSSBS-1083R-A680
Beschreibung:
Tyrosine-protein kinase that acts as a cell-surface receptor for VEGFC and VEGFD, and plays an essential role in adult lymphangiogenesis and in the development of the vascular network and the cardiovascular system during embryonic development. Promotes proliferation, survival and migration of endothelial cells, and regulates angiogenic sprouting. Signaling by activated FLT4 leads to enhanced production of VEGFC, and to a lesser degree VEGFA, thereby creating a positive feedback loop that enhances FLT4 signaling. Modulates KDR signaling by forming heterodimers. Mediates activation of the MAPK1/ERK2, MAPK3/ERK1 signaling pathway, of MAPK8 and the JUN signaling pathway, and of the AKT1 signaling pathway. Phosphorylates SHC1. Mediates phosphorylation of PIK3R1, the regulatory subunit of phosphatidylinositol 3-kinase. Promotes phosphorylation of MAPK8 at 'Thr-183' and 'Tyr-185', and of AKT1 at 'Ser-473'.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-6210R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6210R-A350
Lokale Artikelnummer::
BOSSBS-6210R-A350
Beschreibung:
WD-repeat proteins are a large family of eukaryotic proteins coordinating multi-protein complex assemblies. Their role has been implicated in multiple cellular processes including signal transduction, transcriptional regulation, cell cycle control and apoptosis. NRIP is a novel 860a.a nuclear protein consisting of seven conserved WD40 domains and one NLS motif. It binds to androgen and glucocorticoid receptors and up-regulates their transcriptional activity, thereby functioning as a nuclear receptor co-activator. Role of NRIP has been implicated in cell growth and also in cervical and prostrate cancer, thus indicating a potential therapeutic intervention. Northern Blot analysis detects a high expression of NRIP in skeletal muscle and testis and low expression in heart, prostrate and adrenal gland.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-6775R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6775R-A750
Lokale Artikelnummer::
BOSSBS-6775R-A750
Beschreibung:
FASTKD2 belongs to the FAST kinase family and it contains 1 RAP domain. There are two isoforms.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-4235R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-4235R-A680
Lokale Artikelnummer::
BOSSBS-4235R-A680
Beschreibung:
Receptor for adenosine. The activity of this receptor is mediated by G proteins which inhibit adenylyl cyclase.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-12393R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12393R-A750
Lokale Artikelnummer::
BOSSBS-12393R-A750
Beschreibung:
Involved in signal transduction through the Wnt pathway. Promotes beta-catenin's transcriptional activity.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-8426R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-8426R-A680
Lokale Artikelnummer::
BOSSBS-8426R-A680
Beschreibung:
Component of the MOZ/MORF complex which has a histone H3 acetyltransferase activity.
VE:
1 * 100 µl
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Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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