Boc-(S)-thiazolidine-2-carboxylic+acid
Artikel-Nr:
(BOSSBS-1228R-CY5.5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1228R-CY5.5
Lokale Artikelnummer::
BOSSBS-1228R-CY5.5
Beschreibung:
Clathrin-mediated endocytosis is the pathway by which many receptors for nutrients and hormones are internalized to be recycled or down-regulated. During formation of clathrin coated membranes, clathrin co-assembles with heterotetrameric molecules known as assembly polypeptides (APs) or adaptors which form a layer of protein coat between the clathrin lattice and the membrane. There are two characterized adaptors AP1 and AP2. AP1 is associated with clathrin coated vesicles at the trans-Golgi network and AP2 is associated with the endocytic clathrin coated vesicles at the plasma membrane and has been shown to specifically interact with Shc and EGF receptor. AP2 is composed of four subunits, two separate 100 kDa gene products with similar domain structures (alpha and beta adaptin) and a 50 and 17 kDa subunit. There are two alpha-adaptin genes, alpha A and alpha C which have a tissue specific pattern of expression.
VE:
1 * 100 µl
Lieferant:
BIOLEGEND INC
Beschreibung:
Anti-Cytokeratin 17 Rat Monoclonal Antibody [clone: W16131A] (Alexa Fluor® 488)
Artikel-Nr:
(THSARH60-17-100)
Lieferant:
THERMO SAVANT
Hersteller-Artikelnummer::
RH60-17-100
Lokale Artikelnummer::
THSARH60-17-100
Beschreibung:
Rotor for 60 glass and plastic tubes (17×100 mm, 16×100 mm), for use with SPD2030, SPD300DDA-230
VE:
1 * 1 ST
Lieferant:
BIOLEGEND INC
Beschreibung:
Anti-beta-Amyloid, 17-24 Mouse Monoclonal Antibody [clone: 4G8] (Biotin)
Artikel-Nr:
(PRSI4013P)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
4013P
Lokale Artikelnummer::
PRSI4013P
Beschreibung:
RPA interacting protein peptide is used for blocking the activity of RPA interacting protein antibody.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI3223P)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
3223P
Lokale Artikelnummer::
PRSI3223P
Beschreibung:
SARS Spike peptide is used for blocking the activity of the SARS Spke antibody.
VE:
1 * 50 µG
Lieferant:
SciLabware
Beschreibung:
Gewinderohre, Kupplungen, Phenoplast für Stoßverbindungen, SVL® Verbindungsgröße 22, Ring I.Ø 17 mm
Lieferant:
KARTELL
Beschreibung:
Finned plugs for disposable tubes 11 to 13 mm or 15 to 17 mm in diameter. The finned plug has been carefully designed. Available colours: Neutral (00), blue (04), red (10), green (12) and yellow (06).
Artikel-Nr:
(229-3176)
Lieferant:
Brand
Hersteller-Artikelnummer::
152400
Lokale Artikelnummer::
BRND152400
Beschreibung:
PP, transparent, mit konischen Enden.
VE:
1 * 10 ST
Artikel-Nr:
(BOSSBS-11625R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11625R-HRP
Lokale Artikelnummer::
BOSSBS-11625R-HRP
Beschreibung:
WW domain-binding protein 2 (WBP2) is a 261 amino acid protein expressed in most tissues. The WW domain is composed of 38 to 40 semi-conserved amino acids and is shared by various groups of proteins, including structural, regulatory and signaling proteins. The domain mediates protein-protein interactions through the binding of polyproline ligands. WBP2 binds to the WW domain of Yes-associated protein (YAP), WW domain containing E3 ubiquitin protein ligase 1 (AIP5) and WW domain containing E3 ubiquitin protein ligase 2 (AIP2). The gene encoding WBP2 is located on human chromosome 17, which comprises over 2.5% of the human genome and encodes over 1,200 genes, some of which are involved in tumor suppression and in the pathogenesis of Li-Fraumeni syndrome, early onset breast cancer and a predisposition to cancers of the ovary, colon, prostate gland and fallopian tubes.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5463R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5463R-HRP
Lokale Artikelnummer::
BOSSBS-5463R-HRP
Beschreibung:
The human protooncogene JUN is the putative transforming gene of avian sarcoma virus 17, and it encodes a protein which is highly homologous to the viral protein. cJun (previously known as the Fos binding protein p39) and c Fos form a complex in the nucleus. AP 1 (activating protein 1) is a collective term referring to these dimeric transcription factors composed of Jun, Fos or ATF subunits that bind to a common DNA site, the AP1 binding site. AP 1 proteins, mostly the Jun group, regulate the expression and function of cell cycle regulators such as Cyclin D1, p53, p21 (cip1/waf1), p19 (ARF) and p16. Fos and Jun proto oncogene expression is induced transiently by a variety of extracellular stimuli associated with mitogenesis, differentiation processes or depolarization of neurons. JUN has been mapped to 1p32 to p31, a chromosomal region involved in both translocations and deletions in human malignancies.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11625R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11625R-A647
Lokale Artikelnummer::
BOSSBS-11625R-A647
Beschreibung:
WW domain-binding protein 2 (WBP2) is a 261 amino acid protein expressed in most tissues. The WW domain is composed of 38 to 40 semi-conserved amino acids and is shared by various groups of proteins, including structural, regulatory and signaling proteins. The domain mediates protein-protein interactions through the binding of polyproline ligands. WBP2 binds to the WW domain of Yes-associated protein (YAP), WW domain containing E3 ubiquitin protein ligase 1 (AIP5) and WW domain containing E3 ubiquitin protein ligase 2 (AIP2). The gene encoding WBP2 is located on human chromosome 17, which comprises over 2.5% of the human genome and encodes over 1,200 genes, some of which are involved in tumor suppression and in the pathogenesis of Li-Fraumeni syndrome, early onset breast cancer and a predisposition to cancers of the ovary, colon, prostate gland and fallopian tubes.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-1184R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1184R-A647
Lokale Artikelnummer::
BOSSBS-1184R-A647
Beschreibung:
E3 ubiquitin ligase that, together with UBE2N and UBE2V1, mediates the synthesis of 'Lys-63'-linked-polyubiquitin chains conjugated to proteins, such as IKBKG, IRAK1, AKT1 and AKT2. Also mediates ubiquitination of free/unanchored polyubiquitin chain that leads to MAP3K7 activation (By similarity). Leads to the activation of NF-kappa-B and JUN. May be essential for the formation of functional osteoclasts. Seems to also play a role in dendritic cells (DCs) maturation and/or activation. Represses c-Myb-mediated transactivation, in B-lymphocytes. Adapter protein that seems to play a role in signal transduction initiated via TNF receptor, IL-1 receptor and IL-17 receptor. Regulates osteoclast differentiation by mediating the activation of adapter protein complex 1 (AP-1) and NF-kappa-B, in response to RANK-L stimulation. Together with MAP3K8, mediates CD40 signals that activate ERK in B-cells and macrophages, and thus may play a role in the regulation of immunoglobulin production.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-1228R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1228R-HRP
Lokale Artikelnummer::
BOSSBS-1228R-HRP
Beschreibung:
Clathrin-mediated endocytosis is the pathway by which many receptors for nutrients and hormones are internalized to be recycled or down-regulated. During formation of clathrin coated membranes, clathrin co-assembles with heterotetrameric molecules known as assembly polypeptides (APs) or adaptors which form a layer of protein coat between the clathrin lattice and the membrane. There are two characterized adaptors AP1 and AP2. AP1 is associated with clathrin coated vesicles at the trans-Golgi network and AP2 is associated with the endocytic clathrin coated vesicles at the plasma membrane and has been shown to specifically interact with Shc and EGF receptor. AP2 is composed of four subunits, two separate 100 kDa gene products with similar domain structures (alpha and beta adaptin) and a 50 and 17 kDa subunit. There are two alpha-adaptin genes, alpha A and alpha C which have a tissue specific pattern of expression.
VE:
1 * 100 µl
Lieferant:
BIOLEGEND INC
Beschreibung:
Anti-Cytokeratin 17 Rat Monoclonal Antibody [clone: W16131A] (Alexa Fluor® 647)
Artikel-Nr:
(BLEG371225)
Lieferant:
BIOLEGEND INC
Hersteller-Artikelnummer::
371225
Lokale Artikelnummer::
BLEG371225
Beschreibung:
Anti-CD357 (GITR) Mouse Monoclonal Antibody [clone: 108-17] (TotalSeq™-A0360)
VE:
1 * 10 µG
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