4'-Cyanacetanilid
Artikel-Nr:
(BOSSBS-8056R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-8056R-CY5
Lokale Artikelnummer::
BOSSBS-8056R-CY5
Beschreibung:
KLHL14 is a member of the KLHL family. The kelch motif was initially discovered in Kelch. In this protein there are six copies of the motif. It has been shown for one member that it is related to Galactose Oxidase for which a structure has been solved. Two isoforms of this protein exist - 70kDa and 43kDa.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-8312R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-8312R
Lokale Artikelnummer::
BOSSBS-8312R
Beschreibung:
The second largest human chromosome, 2 consists of 237 million bases encoding over 1,400 genes and making up approximately 8% of the human genome. A number of genetic diseases are linked to genes on chromosome 2. Harlequin icthyosis, a rare and morbid skin deformity, is associated with mutations in the ABCA12 gene. The lipid metabolic disorder sitosterolemia is associated with ABCG5 and ABCG8. An extremely rare recessive genetic disorder, Alstré°‰ syndrome is due to mutations in the ALMS1 gene. Interestingly, chromosome 2 contains what appears to be a vestigial second centromere and vestigial telomeres which gives credence to the hypothesis that human chromosome 2 is the result of an ancient fusion of two ancestral chromosomes seen in modern form today in apes. The FAM82A gene product has been provisionally designated FAM82A pending further characterization.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9665R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9665R-A488
Lokale Artikelnummer::
BOSSBS-9665R-A488
Beschreibung:
Plays a role in the incorporation of pigments into hair. May function in membrane fusion and regulate the biogenesis of disk membranes of photoreceptor rod cells (By similarity).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-2335R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-2335R
Lokale Artikelnummer::
BOSSBS-2335R
Beschreibung:
Anti-PGK1 Rabbit Polyclonal Antibody
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-10505R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-10505R-CY3
Lokale Artikelnummer::
BOSSBS-10505R-CY3
Beschreibung:
The protein encoded by this gene is similar in sequence to tubulointerstitial nephritis antigen, a secreted glycoprotein that is recognized by in some types of immune-related tubulointerstitial nephritis. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2011].
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9630R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9630R-A555
Lokale Artikelnummer::
BOSSBS-9630R-A555
Beschreibung:
C16orf48
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-1445R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1445R-CY3
Lokale Artikelnummer::
BOSSBS-1445R-CY3
Beschreibung:
Plays an important role in the regulation of interdigestive gastrointestinal motility and indirectly causes rhythmic contraction of duodenal and colonic smooth muscle.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-0409R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0409R-A750
Lokale Artikelnummer::
BOSSBS-0409R-A750
Beschreibung:
May function as part of a signaling pathway that acts to regulate the size of the body fat depot. An increase in the level of LEP may act directly or indirectly on the CNS to inhibit food intake and/or regulate energy expenditure as part of a homeostatic mechanism to maintain constancy of the adipose mass.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-0408R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0408R-A750
Lokale Artikelnummer::
BOSSBS-0408R-A750
Beschreibung:
Heamachrome.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-1910R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1910R-A750
Lokale Artikelnummer::
BOSSBS-1910R-A750
Beschreibung:
Membrane Receptors Transforming growth factor beta is a multifunctional cytokine known to modulate several tissue development and repair processes, including cell differentiation, cell cycle progression, cellular migration, adhesion, and extracellular matrix production. There are 3 forms encoded by separate genes TGFB1, TGFB2, and TGFB3. The diverse effects of TGF beta are mediated by the TGF beta receptors and cell surface binding proteins. In addition to type I TGF beta receptor (TGFBR1) and type II (TFGBR2), type III (TGF beta III receptor) has been identified. It is a glycoprotein that binds TGF beta and exists in both a membrane bound and a soluble form. It may serve as a receptor accessory molecule in both the TGF beta and fibroblast growth factor systems. TGF beta III receptor lacks a recognizable signaling domain and has no clearly defined role in TGF beta signaling. Endothelial cells undergoing epithelial mesenchymal transformation express TGF beta III receptor, and TGF beta III receptor specific antisera inhibits mesenchyme formation and migration. Misexpression of TGF beta III receptor in nontransforming ventricular endothelial cells conferrs transformation in response to TGFB2. These results support a model where TGF beta III receptor localises transformation in the heart and plays an essential, nonredundant role in TGF beta signaling. TGF beta III receptor, or beta glycan, can function as an inhibin coreceptor with ActRII. TGF beta III receptor binds inhibin with high affinity and enhances binding in cells coexpressing ActRII and TGF beta III receptor. Inhibin forms crosslinked complexes with both recombinant and endogenously expressed TGF beta III receptor and ActRII. TGF beta III receptor confers inhibin sensitivity to cell lines that otherwise respond poorly to this hormone.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-4878R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-4878R
Lokale Artikelnummer::
BOSSBS-4878R
Beschreibung:
The complement factor C3 consists of an alpha and a beta chain. C3 is a central factor in the complement cascade. It is central to the alternative pathway that leads to the C3 convertase C3bBb. The classical mannose binding lectin activation pathway leads to the C3 convertase C4b2a. These convertases cleave C3 resulting in C3a and C3b. Further degradation leads to the formation of the alpha chain products C3d, C3g and C3c. C3 is an acute phase protein that is produced by a wide range of tissues, including renal epithelial cells and hepatocytes.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5234R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5234R-A350
Lokale Artikelnummer::
BOSSBS-5234R-A350
Beschreibung:
Potent inhibitor of cell death. Inhibits activation of caspases. Appears to regulate cell death by blocking the voltage-dependent anion channel (VDAC) by binding to it and preventing the release of the caspase activator, CYC1, from the mitochondrial membrane. Also acts as a regulator of G2 checkpoint and progression to cytokinesis during mitosis. Isoform Bcl-X(L) also regulates presynaptic plasticity, including neurotransmitter release and recovery, number of axonal mitochondria as well as size and number of synaptic vesicle clusters. During synaptic stimulation, increases ATP availability from mitochondria through regulation of mitochondrial membrane ATP synthase F(1)F(0) activity and regulates endocytic vesicle retrieval in hippocampal neurons through association with DMN1L and stimulation of its GTPase activity in synaptic vesicles. Isoform Bcl-X(S) promotes apoptosis.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5020R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5020R-HRP
Lokale Artikelnummer::
BOSSBS-5020R-HRP
Beschreibung:
Plays a role in lipoprotein assembly and dietary cholesterol absorption. In addition to its acyltransferase activity, it may act as a ligase. May provide cholesteryl esters for lipoprotein secretion from hepatocytes and intestinal mucosa.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5693R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5693R-CY3
Lokale Artikelnummer::
BOSSBS-5693R-CY3
Beschreibung:
As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. In the cellular response to DNA damage, the RPA complex controls DNA repair and DNA damage checkpoint activation. Through recruitment of ATRIP activates the ATR kinase a master regulator of the DNA damage response. It is required for the recruitment of the DNA double-strand break repair factors RAD51 and RAD52 to chromatin in response to DNA damage. Also recruits to sites of DNA damage proteins like XPA and XPG that are involved in nucleotide excision repair and is required for this mechanism of DNA repair. Plays also a role in base excision repair (BER) probably through interaction with UNG. Through RFWD3 may activate CHEK1 and play a role in replication checkpoint control. Also recruits SMARCAL1/HARP, which is involved in replication fork restart, to sites of DNA damage. May also play a role in telomere maintenance.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-6431R-CY5.5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6431R-CY5.5
Lokale Artikelnummer::
BOSSBS-6431R-CY5.5
Beschreibung:
Receptor for lutropin-choriogonadotropic hormone. The activity of this receptor is mediated by G proteins which activate adenylate cyclase.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9505R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9505R
Lokale Artikelnummer::
BOSSBS-9505R
Beschreibung:
Anti-A2M Rabbit Polyclonal Antibody
VE:
1 * 100 µl
Preis auf Anfrage
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