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3-(3-Methoxyphenoxy)butan-2-one
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3-(3-Methoxyphenoxy)butan-2-one
Artikel-Nr:
(USBIA3999-87-APC)
Lieferant:
US Biological
Hersteller-Artikelnummer::
A3999-87-APC
Lokale Artikelnummer::
USBIA3999-87-APC
Beschreibung:
Anti-ATP12A Rabbit Polyclonal Antibody (APC (Allophycocyanin))
VE:
1 * 200 µl
Artikel-Nr:
(BOSSBS-5356R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5356R-A488
Lokale Artikelnummer::
BOSSBS-5356R-A488
Beschreibung:
Receptor for GABA. The activity of this receptor is mediated by G-proteins that inhibit adenylyl cyclase activity, stimulates phospholipase A2, activates potassium channels, inactivates voltage-dependent calcium-channels and modulates inositol phospholipids hydrolysis. Plays a critical role in the fine-tuning of inhibitory synaptic transmission. Pre-synaptic GABA-B-R inhibit neurotransmitter release by down-regulating high-voltage activated calcium channels, whereas postsynaptic GABA-B-R decrease neuronal excitability by activating a prominent inwardly rectifying potassium (Kir) conductance that underlies the late inhibitory postsynaptic potentials. Not only implicated in synaptic inhibition but also in hippocampal long-term potentiation, slow wave sleep, muscle relaxation and antinociception.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-12179R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12179R-A555
Lokale Artikelnummer::
BOSSBS-12179R-A555
Beschreibung:
The KIR family of potassium channels possess a greater tendency to allow potassium to flow into the cell rather than out of it. Kir4.1, also known as Kir1.2, is highly expressed in brain including glial cells, astrocytes and cortical neurons. Kir4.1 is also expressed in myelin-synthesizing oligodendrocytes and is crucial to myelination in the developing nervous system. The gene encoding human Kir4.1 maps to chromosome 1. Kir4.2, also known as Kir1.3, is expressed in kidney, lung, heart, thymus and thyroid during development. The gene encoding human Kir4.2 maps to chromosome 21 in the Down syndrome chromosome region 1, and Kir4.2 may play a role in the pathogenesis of Down’s syndrome. Kir 5.1 forms functional channels only by coexpression with either Kir4.1 or Kir4.2 in the kidney and pancreas. The gene encoding human Kir5.1 maps to chromosome 17.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-12179R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12179R-A647
Lokale Artikelnummer::
BOSSBS-12179R-A647
Beschreibung:
The KIR family of potassium channels possess a greater tendency to allow potassium to flow into the cell rather than out of it. Kir4.1, also known as Kir1.2, is highly expressed in brain including glial cells, astrocytes and cortical neurons. Kir4.1 is also expressed in myelin-synthesizing oligodendrocytes and is crucial to myelination in the developing nervous system. The gene encoding human Kir4.1 maps to chromosome 1. Kir4.2, also known as Kir1.3, is expressed in kidney, lung, heart, thymus and thyroid during development. The gene encoding human Kir4.2 maps to chromosome 21 in the Down syndrome chromosome region 1, and Kir4.2 may play a role in the pathogenesis of Down’s syndrome. Kir 5.1 forms functional channels only by coexpression with either Kir4.1 or Kir4.2 in the kidney and pancreas. The gene encoding human Kir5.1 maps to chromosome 17.
VE:
1 * 100 µl
Artikel-Nr:
(87765.290)
Lieferant:
VWR Chemicals
Lokale Artikelnummer::
VWRC87765.290
Beschreibung:
Starting materials: Aluminium chloride R / Glacial acetic acid R/ Methanol R.
VE:
1 * 1 L
Artikel-Nr:
(BOSSBS-11528R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11528R-CY3
Lokale Artikelnummer::
BOSSBS-11528R-CY3
Beschreibung:
GALR3 a 368 and 370 amino acid protein in human and rat, respectively, belongs to a family of G protein-coupled receptors that bind the neuropeptide galanin, which is distributed throughout the central and peripheral nervous system, the pituitary gland, the gastrointestinal tract and in the endocrine and exocrine pancreas. GALR3 mRNA is widely distributed, but expressed at low abundance. In human, GALR3 mRNA is highly expressed in the hypothalamus, pituitary and testis, and is expressed to a lesser extent in adrenal gland and pancreas. Rat and human GALR3 co-express with potassium channel subunits GIRK1 and GIRK4. Like GALR1, GALR3 signaling pathways lead to the inhibition of adenylate cyclase and to the activation of potassium channels, which are linked to the regulation of neurotransmitter release. Binding of galanin to galanin receptors results in increased feeding, impaired learning, enhanced opiate analgesia and decreased opiate place preference.
VE:
1 * 100 µl
Lieferant:
Alfa Aesar
Beschreibung:
Aluminiumfluorid, wasserfrei ≥99,5%
Artikel-Nr:
(BOSSBS-1122R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1122R-A555
Lokale Artikelnummer::
BOSSBS-1122R-A555
Beschreibung:
The semaphorins are a family of proteins that are involved in signaling. All the family members have a secretion signal, a 500-amino acid sema domain, and 16 conserved cysteine residues(Kolodkin et al., 1993 [PubMed 8269517]). Sequence comparisons have grouped the secreted semaphorins into 3 general classes, all of which also have an immunoglobulin domain. The semaphorin III family, consisting of human semaphorin III (SEMA3A; MIM 603961), chicken collapsin, and mouse semaphorins A, D, and E, all have a basic domain at the C terminus. Chicken collapsin contributes to path finding by axons during development by inhibiting extension of growth cones (Luo et al., 1993 [PubMed 8402908]) through an interaction with a collapsin response mediator protein of relative molecular mass 62K (CRMP62) (Goshima et al., 1995 [PubMed7637782]), a putative homolog of an axonal guidance associated UNC33 gene product (MIM 601168). SEMA3F is a secreted member of the semaphorin III family.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3973R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3973R-CY3
Lokale Artikelnummer::
BOSSBS-3973R-CY3
Beschreibung:
UQCRC2 is a component of the ubiquinol cytochrome c reductase complex (complex III), which is part of the mitochondrial respiratory chain. The core protein 2 is required for the assembly of the complex.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3973R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3973R
Lokale Artikelnummer::
BOSSBS-3973R
Beschreibung:
UQCRC2 is a component of the ubiquinol cytochrome c reductase complex (complex III), which is part of the mitochondrial respiratory chain. The core protein 2 is required for the assembly of the complex.
VE:
1 * 100 µl
Artikel-Nr:
(BSENR-1401-50)
Lieferant:
Biosensis
Hersteller-Artikelnummer::
R-1401-50
Lokale Artikelnummer::
BSENR-1401-50
Beschreibung:
Peripherin is a class-III neuronal intermediate filament protein found in certain classes of neuron, most of which are located in the peripheral nervous system.
VE:
1 * 50 µl
Artikel-Nr:
(BOSSBS-6671R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6671R-A680
Lokale Artikelnummer::
BOSSBS-6671R-A680
Beschreibung:
Pore-forming (alpha) subunit of voltage-gated rapidly inactivating A-type potassium channels. May contribute to I(To) current in heart and I(Sa) current in neurons. Channel properties are modulated by interactions with other alpha subunits and with regulatory subunits.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5039R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5039R-A555
Lokale Artikelnummer::
BOSSBS-5039R-A555
Beschreibung:
Apolipoprotein E, a main apoprotein of the chylomicron, binds to a specific receptor on liver cells and peripheral cells and is essential for the normal catabolism of triglyceride-rich lipoprotein constituents.ApoE exists in three major isoforms; E2, E3, and E4, which differ from one another by a single amino-acid substitution. Compared with E3 and E4, E2 exhibits the lowest receptor binding affinity. Defects in ApoE are a cause of hyperlipoproteinemia type III due to increased plasma cholesterol and triglycerides levels which are the consequence of impaired clearance of chylomicron and VLDL remnants.Summary: Chylomicron remnants and very low density lipoprotein (VLDL) remnants are rapidly removed from the circulation by receptor-mediated endocytosis in the liver. Apolipoprotein E, a main apoprotein of the chylomicron, binds to a specific receptor on liver cells and peripheral cells. ApoE is essential for the normal catabolism of triglyceride-rich lipoprotein constituents. The APOE gene is mapped to chromosome 19 in a cluster with APOC1 and APOC2. Defects in apolipoprotein E result in familial dysbetalipoproteinemia, or type III hyperlipoproteinemia (HLP III), in which increased plasma cholesterol and triglycerides are the consequence of impaired clearance of chylomicron and VLDL remnants. [provided by RefSeq, Jul 2008].
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5039R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5039R-CY7
Lokale Artikelnummer::
BOSSBS-5039R-CY7
Beschreibung:
Apolipoprotein E, a main apoprotein of the chylomicron, binds to a specific receptor on liver cells and peripheral cells and is essential for the normal catabolism of triglyceride-rich lipoprotein constituents.ApoE exists in three major isoforms; E2, E3, and E4, which differ from one another by a single amino-acid substitution. Compared with E3 and E4, E2 exhibits the lowest receptor binding affinity. Defects in ApoE are a cause of hyperlipoproteinemia type III due to increased plasma cholesterol and triglycerides levels which are the consequence of impaired clearance of chylomicron and VLDL remnants.Summary: Chylomicron remnants and very low density lipoprotein (VLDL) remnants are rapidly removed from the circulation by receptor-mediated endocytosis in the liver. Apolipoprotein E, a main apoprotein of the chylomicron, binds to a specific receptor on liver cells and peripheral cells. ApoE is essential for the normal catabolism of triglyceride-rich lipoprotein constituents. The APOE gene is mapped to chromosome 19 in a cluster with APOC1 and APOC2. Defects in apolipoprotein E result in familial dysbetalipoproteinemia, or type III hyperlipoproteinemia (HLP III), in which increased plasma cholesterol and triglycerides are the consequence of impaired clearance of chylomicron and VLDL remnants. [provided by RefSeq, Jul 2008].
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-1122R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1122R-A750
Lokale Artikelnummer::
BOSSBS-1122R-A750
Beschreibung:
The semaphorins are a family of proteins that are involved in signaling. All the family members have a secretion signal, a 500-amino acid sema domain, and 16 conserved cysteine residues(Kolodkin et al., 1993 [PubMed 8269517]). Sequence comparisons have grouped the secreted semaphorins into 3 general classes, all of which also have an immunoglobulin domain. The semaphorin III family, consisting of human semaphorin III (SEMA3A; MIM 603961), chicken collapsin, and mouse semaphorins A, D, and E, all have a basic domain at the C terminus. Chicken collapsin contributes to path finding by axons during development by inhibiting extension of growth cones (Luo et al., 1993 [PubMed 8402908]) through an interaction with a collapsin response mediator protein of relative molecular mass 62K (CRMP62) (Goshima et al., 1995 [PubMed7637782]), a putative homolog of an axonal guidance associated UNC33 gene product (MIM 601168). SEMA3F is a secreted member of the semaphorin III family.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11998R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11998R-A488
Lokale Artikelnummer::
BOSSBS-11998R-A488
Beschreibung:
The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. Primary transducing effect is inhibition of adenylate cyclase.
VE:
1 * 100 µl
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Dieses Produkt kann nur an eine Lieferadresse versandt werden die über die entsprechende Lizenzen verfügt. Für weitere Hilfe bitte kontaktieren Sie Ihr VWR Vertriebszentrum.
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