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Bis(4-tert-butylphenyl)iodonium-p-toluenesulphonate
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Bis(4-tert-butylphenyl)iodonium-p-toluenesulphonate
Artikel-Nr:
(20447-1MG)
Lieferant:
Biotium
Hersteller-Artikelnummer::
20447-1MG
Lokale Artikelnummer::
BTIU20447-1MG
Beschreibung:
Goat anti-human IgG, Fc gamma specific antibody reacts specifically with the human IgG heavy (γ) chains and not with light chains and F(ab’)2 fragment on all human immunoglobulins. To minimize cross-reactivity, it has been adsorbed against bovine, horse, mouse and rabbit serum proteins prior to conjugation. CF™640R (Ex/Em 642/662 nm) is a novel far-red rhodamine-based dye spectrally similar to Cy®5 and Alexa Fluor® 647. CF™640R is much brighter than Cy®5 and at least as bright as Alexa Fluor® 647 when excited at 633 or 635 nm. However, the most important advantage of CF™640R is its exceptional photostability.
Alexa Fluor® is a registered trademark of Thermo Fisher Scientific. Cy®5 is a registered trademark of GE Healthcare.
VE:
1 * 1 mg
Artikel-Nr:
(NOVUNBP1-79952)
Lieferant:
Novus Biologicals
Hersteller-Artikelnummer::
NBP1-79952
Lokale Artikelnummer::
NOVUNBP1-79952
Beschreibung:
Rabbit Polyclonal Nicotinic Acetylcholine Receptor gamma Antibody. Tested Applications: Western Blot. Tested Reactivity: Human, Mouse, Rat, Bovine, Canine.
VE:
1 * 50 µG
Lieferant:
APOLLO SCIENTIFIC
Beschreibung:
1,6-Anhydro-β-D-glucose
Artikel-Nr:
(31618-100MG)
Lieferant:
Sigma-Aldrich
Hersteller-Artikelnummer::
31618-100MG
Lokale Artikelnummer::
SUPL31618-100MG
Beschreibung:
2-Naphthylamin, Supelco®
VE:
1 * 100 mg
Lieferant:
Biotium
Beschreibung:
Recognizes a 77-85 kDa protein, identified as cellular or tissue transglutaminase II (TGase II). Transglutaminases are enzymes that catalyze the crosslinking of proteins by epsilon-gamma glutamyl lysine isopeptide bonds. While the primary structure of transglutaminases is not conserved, they all have the same amino acid sequence at their active sites and their activity is calcium-dependent. The protein encoded by this gene acts as a monomer, is induced by retinoic acid, and appears to be involved in apoptosis. Finally, the encoded protein is the autoantigen implicated in celiac disease. The identification of transglutaminase as the main antigen of endomysium antibodies allows a new diagnostic approach to celiac disease (CD), a genetic, immunologically mediated small bowel enteropathy that causes malabsorption. TGase II is implicated in programmed cell death, signal transduction, drug-resistance, cell growth, endocytosis, insulin secretion, cell adhesion, cataract formation, and wound healing.
Artikel-Nr:
(BOSSBS-2374R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-2374R-A488
Lokale Artikelnummer::
BOSSBS-2374R-A488
Beschreibung:
TAP is an integral transmembrane protein involved in the transport of antigens from the cytoplasm to the endoplasmic reticulum for association with MHC class I molecules. It is a heterodimer of TAP1 and TAP2, and the peptide-binding site is shared between the cytoplasmic loops of TAP1 and TAP2. TAP is inducible by interferon gamma and belongs to the ABC transporter family, MDR subfamily. TAP also acts as a molecular scaffold for the final stage of MHC class I folding, namely the binding of peptide. Nascent MHC class I molecules associate with TAP via tapasin. TAP is inhibited by the covalent attachment of herpes simplex virus ICP47 protein, which blocks the peptide-binding site of TAP. It is inhibited by human cytomegalovirus US6 glycoprotein, which binds to the lumenal side of the TAP complex and inhibits peptide translocation by specifically blocking ATP-binding to TAP and prevents the conformational rearrangement of TAP induced by peptide binding.
VE:
1 * 100 µl
Lieferant:
EDVOTEK
Beschreibung:
Die drei gebräuchlichsten Restriktionsenzyme sind EcoRI, BamHI und HindIII. Jedes der Enzyme katalysiert die Spaltung bei der jeweiligen definierten Basensequenz. Alle Enzyme sind lyophilisiert und enthalten 1500 Einheiten. Eine Einheit ist definiert als die Enzymmenge, die erforderlich ist, um 1,0 µg Lambda-DNA in 60 Minuten bei 37 °C in einer Reaktionsmischung von insgesamt 50 µl abzubauen.
Artikel-Nr:
(BOSSBS-3345R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3345R-CY7
Lokale Artikelnummer::
BOSSBS-3345R-CY7
Beschreibung:
Serine/threonine-protein kinase that performs several important functions throughout M phase of the cell cycle, including the regulation of centrosome maturation and spindle assembly, the removal of cohesins from chromosome arms, the inactivation of APC/C inhibitors, and the regulation of mitotic exit and cytokinesis. Required for recovery after DNA damage checkpoint and entry into mitosis. Required for kinetochore localization of BUB1B. Phosphorylates SGOL1. Required for spindle pole localization of isoform 3 of SGOL1 and plays a role in regulating its centriole cohesion function. Phosphorylates BORA, and thereby promotes the degradation of BORA. Contributes to the regulation of AURKA function. Regulates TP53 stability through phosphorylation of TOPORS. Phosphorylates NEDD1. NEDD1 phosphorylation promotes subsequent targeting of the gamma-tubulin ring complex (gTuRC) to the centrosome, an important step for spindle formation. Phosphorylates both ECT2 and RACGAP1, and thereby stimulates their interaction that is essential for the cleavage furrow formation. Promotes the central spindle recruitment of ECT2.
VE:
1 * 100 µl
Lieferant:
Merck
Beschreibung:
β-Nicotinamid-Adenin-Dinucleotid, oxidierte Form (NAD)), Millipore®
Artikel-Nr:
(BSBTPB9024)
Lieferant:
BosterBio
Hersteller-Artikelnummer::
PB9024
Lokale Artikelnummer::
BSBTPB9024
Beschreibung:
Polyclonal antibody for INTERFERON GAMMA/IFNG detection. Host: Rabbit.Size: 100μg/vial. Tested applications: ELISA. Reactive species: Rat. INTERFERON GAMMA/IFNG information: Molecular Weight: 17918 MW; Subcellular Localization: Secreted; Tissue Specificity: Released primarily from activated T lymphocytes.
VE:
1 * 100 µG
Artikel-Nr:
(STMC100-1413)
Lieferant:
Stemcell Technologies
Hersteller-Artikelnummer::
100-1413
Lokale Artikelnummer::
STMC100-1413
Beschreibung:
Stimulating T cells with CMV (IE-1) peptide pool releases downstream cytokines and upregulates activation markers, enabling antigen-specific T cells to be detected or isolated for analysis. CMV (IE-1) peptide pool is a lyophilised mixture of 120 peptides from the immediate early protein IE1 (IE1) of human cytomegalovirus (CMV; strain AD169), and consists of 15-mer peptides with 11-amino-acid overlaps that cover amino acids 1 to 491 on IE1. CMV IE1 is a transcriptional transactivator and autoregulator (Cherrington and Mocarski). Studies show that IE1 promotes viral transcription by antagonizing histone deacetylation (Nevels <i>et al.</i>) and, along with IE2, may contribute to the survival of CMV-infected cells by blocking tumor necrosis factor alpha (TNF-α)-induced apoptosis (Zhu <i>et al.</i>). Viral peptide pools are useful for a broad range of applications, including vaccine development, immunological research, and diagnostic assay development.
VE:
1 * 1 LE
New Product
 This is a MarketSource item. Additional charges may apply
Artikel-Nr:
(APOSBISN0149-5MG)
Lieferant:
APOLLO SCIENTIFIC
Hersteller-Artikelnummer::
BISN0149-5MG
Lokale Artikelnummer::
APOSBISN0149-5MG
Beschreibung:
Lapachone is a naturally occurring quinone obtained from the bark of the lapacho tree (Tabebuia avellanedae) with cancer chemopreventive properties and a potent inhibitor of IDO1 (IC500.44 M).
VE:
1 * 5 mg
Artikel-Nr:
(USBI130510)
Lieferant:
US Biological
Hersteller-Artikelnummer::
130510
Lokale Artikelnummer::
USBI130510
Beschreibung:
Anti-NPPB Rabbit Polyclonal Antibody
VE:
1 * 100 µG
Lieferant:
APOLLO SCIENTIFIC
Beschreibung:
Substrate for N-Acetyl-b-D-glucosaminidase
Lieferant:
Sigma-Aldrich
Beschreibung:
2,3,4,6-Tetra-O-acetyl-β-D-glucopyranosyl isothiocyanate is a chiral derivatization reagent which reacts mainly with enantiomeric amino acids.
Artikel-Nr:
(BOSSBS-2485R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-2485R-A680
Lokale Artikelnummer::
BOSSBS-2485R-A680
Beschreibung:
JAK2 (Janus Activating Kinase 2) is a tyrosine kinase of the non-receptor type, that associates with the intracellular domains of cytokine receptors; JAK2 is the predominant JAK kinase activated in response to several growth factors and cytokines such as IL-3, GM-CSF and erythropoietin; it has been found to be constitutively associated with the prolactin receptor and is required for responses to gamma interferon. Ligand binding to a variety of cell surface receptors (e.g., cytokine, growth factor, GPCRs) leads to an association of those receptors with JAK proteins, which are then activated via phosphorylation on tyrosines 1007 and 1008 in the kinase activation loop. Activated JAK proteins phosphorylate and activate STAT (signal transducers and activators of transcription) proteins, which then dimerize and translocate to the nucleus. Once in the nucleus, STAT proteins bind to DNA and modify the transcription of various genes.
VE:
1 * 100 µl
Preis auf Anfrage
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Dieses Produkt kann nur an eine Lieferadresse versandt werden die über die entsprechende Lizenzen verfügt. Für weitere Hilfe bitte kontaktieren Sie Ihr VWR Vertriebszentrum.
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