Methyl+3-bromo-5-methylpyridine-2-carboxylate
Lieferant:
EDQM
Beschreibung:
Organic Standard, Azathioprine impurity A, 1-methyl-4-nitro-1H-imidazol-5-amine, Ph. Eur. standard
Artikel-Nr:
(BOSSBS-12460R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12460R-HRP
Lokale Artikelnummer::
BOSSBS-12460R-HRP
Beschreibung:
Aldehyde dehydrogenases (ALDHs) mediate NADP+-dependent oxidation of aldehydes into acids during the detoxification of alcohol-derived acetaldehyde; metabolism of corticosteroids, biogenic amines and neurotransmitters; and lipid peroxidation. ALDH1A1, also designated retinal dehydrogenase 1 (RalDH1 or RALDH1), aldehyde dehydrogenase family 1 member A1, aldehyde dehydrogenase cytosolic, ALDHII, ALDH-E1 or ALDH E1, is a retinal dehydrogenase that participates in the biosynthesis of retinoic acid (RA). There are two major liver isoforms of ALDH1 that can localize to cytosolic or mitochondrial space. The ALDH1A2 (RALDH2, RALDH2-T) gene produces three different transcripts and also catalyzes the synthesis of RA from retinaldehyde. ALDH1A3 (ALDH6, RALDH3, ALDH1A6) is a 37 kb gene that consists of 13 exons and produces a major transcript of approximately 3.5 kb most abundant in salivary gland, stomach and kidney. ALDH3A1 (stomach type, ALDH3, ALDHIII) forms a cytoplasmic homodimer that preferentially oxidizes aromatic aldehyde substrates. ALDH genes upregulate as a part of the oxidative stress response, and appear to be abundant in certain tumors that have an accelerated metabolism toward chemotherapy agents.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-4176R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-4176R-A750
Lokale Artikelnummer::
BOSSBS-4176R-A750
Beschreibung:
Functions as a polyspecific organic cation transporter, efficiently transporting many organic cations such as monoamine neurotransmitters 1-methyl-4-phenylpyridinium and biogenic amines including serotonin, dopamine, norepinephrine and epinephrine. May play a role in regulating central nervous system homeostasis of monoamine neurotransmitters. May be involved in luminal transport of organic cations in the kidney and seems to use luminal proton gradient to drive organic cation reabsorption. Does not seem to transport nucleoside and nucleoside analogs such as uridine, cytidine, thymidine, adenosine, inosine, guanosine, and azidothymidine. In (PubMed:16873718) adenosine is efficiently transported but in a fashion highly sensitive to extracellular pH, with maximal activity in the pH range 5.5 to 6.5. Glu-206 is essential for the cation selectivity and may function as the charge sensor for cationic substrates. Transport is chloride and sodium-independent but appears to be sensitive to changes in membrane potential. Weakly inhibited by the classical inhibitors of equilibrative nucleoside transport, dipyridamole, dilazep, and nitrobenzylthioinosine. May play a role in the regulation of extracellular adenosine concentrations in cardiac tissues, in particular during ischemia.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-4176R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-4176R-A555
Lokale Artikelnummer::
BOSSBS-4176R-A555
Beschreibung:
Functions as a polyspecific organic cation transporter, efficiently transporting many organic cations such as monoamine neurotransmitters 1-methyl-4-phenylpyridinium and biogenic amines including serotonin, dopamine, norepinephrine and epinephrine. May play a role in regulating central nervous system homeostasis of monoamine neurotransmitters. May be involved in luminal transport of organic cations in the kidney and seems to use luminal proton gradient to drive organic cation reabsorption. Does not seem to transport nucleoside and nucleoside analogs such as uridine, cytidine, thymidine, adenosine, inosine, guanosine, and azidothymidine. In (PubMed:16873718) adenosine is efficiently transported but in a fashion highly sensitive to extracellular pH, with maximal activity in the pH range 5.5 to 6.5. Glu-206 is essential for the cation selectivity and may function as the charge sensor for cationic substrates. Transport is chloride and sodium-independent but appears to be sensitive to changes in membrane potential. Weakly inhibited by the classical inhibitors of equilibrative nucleoside transport, dipyridamole, dilazep, and nitrobenzylthioinosine. May play a role in the regulation of extracellular adenosine concentrations in cardiac tissues, in particular during ischemia.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-4176R-CY5.5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-4176R-CY5.5
Lokale Artikelnummer::
BOSSBS-4176R-CY5.5
Beschreibung:
Functions as a polyspecific organic cation transporter, efficiently transporting many organic cations such as monoamine neurotransmitters 1-methyl-4-phenylpyridinium and biogenic amines including serotonin, dopamine, norepinephrine and epinephrine. May play a role in regulating central nervous system homeostasis of monoamine neurotransmitters. May be involved in luminal transport of organic cations in the kidney and seems to use luminal proton gradient to drive organic cation reabsorption. Does not seem to transport nucleoside and nucleoside analogs such as uridine, cytidine, thymidine, adenosine, inosine, guanosine, and azidothymidine. In (PubMed:16873718) adenosine is efficiently transported but in a fashion highly sensitive to extracellular pH, with maximal activity in the pH range 5.5 to 6.5. Glu-206 is essential for the cation selectivity and may function as the charge sensor for cationic substrates. Transport is chloride and sodium-independent but appears to be sensitive to changes in membrane potential. Weakly inhibited by the classical inhibitors of equilibrative nucleoside transport, dipyridamole, dilazep, and nitrobenzylthioinosine. May play a role in the regulation of extracellular adenosine concentrations in cardiac tissues, in particular during ischemia.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-4176R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-4176R-CY5
Lokale Artikelnummer::
BOSSBS-4176R-CY5
Beschreibung:
Functions as a polyspecific organic cation transporter, efficiently transporting many organic cations such as monoamine neurotransmitters 1-methyl-4-phenylpyridinium and biogenic amines including serotonin, dopamine, norepinephrine and epinephrine. May play a role in regulating central nervous system homeostasis of monoamine neurotransmitters. May be involved in luminal transport of organic cations in the kidney and seems to use luminal proton gradient to drive organic cation reabsorption. Does not seem to transport nucleoside and nucleoside analogs such as uridine, cytidine, thymidine, adenosine, inosine, guanosine, and azidothymidine. In (PubMed:16873718) adenosine is efficiently transported but in a fashion highly sensitive to extracellular pH, with maximal activity in the pH range 5.5 to 6.5. Glu-206 is essential for the cation selectivity and may function as the charge sensor for cationic substrates. Transport is chloride and sodium-independent but appears to be sensitive to changes in membrane potential. Weakly inhibited by the classical inhibitors of equilibrative nucleoside transport, dipyridamole, dilazep, and nitrobenzylthioinosine. May play a role in the regulation of extracellular adenosine concentrations in cardiac tissues, in particular during ischemia.
VE:
1 * 100 µl
Artikel-Nr:
(FLUO033441-1G)
Lieferant:
FLUOROCHEM
Hersteller-Artikelnummer::
033441-1G
Lokale Artikelnummer::
FLUO033441-1G
Beschreibung:
2-Amino-5-fluorbenzothiazol
VE:
1 * 1 g
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Artikel-Nr:
(MOLEM22156050)
Lieferant:
Molekula
Hersteller-Artikelnummer::
M22156050
Lokale Artikelnummer::
MOLEM22156050
Beschreibung:
8-Bromadenin
VE:
1 * 250 mg
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Lieferant:
Sigma-Aldrich
Beschreibung:
(±)-1,2,3,4-Tetrahydro-1-naphthylamin, Sigma-Aldrich®
Artikel-Nr:
(MOLEM75990279)
Lieferant:
Molekula
Hersteller-Artikelnummer::
M75990279
Lokale Artikelnummer::
MOLEM75990279
Beschreibung:
3-Aminochinolin
VE:
1 * 5 g
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Lieferant:
Alfa Aesar
Beschreibung:
8-Bromadenin
Artikel-Nr:
(HONCR1213-10MG)
Lieferant:
Honeywell Chemicals
Hersteller-Artikelnummer::
R1213-10MG
Lokale Artikelnummer::
HONCR1213-10MG
Beschreibung:
High quality inorganic and organic reference materials produced according to ISO 9001.
VE:
1 * 10 mg
Artikel-Nr:
(HONCR1399-10MG)
Lieferant:
Honeywell Chemicals
Hersteller-Artikelnummer::
R1399-10MG
Lokale Artikelnummer::
HONCR1399-10MG
Beschreibung:
High quality inorganic and organic reference materials produced according to ISO 9001.
VE:
1 * 10 mg
Artikel-Nr:
(REST20999)
Lieferant:
Restek
Hersteller-Artikelnummer::
20999
Lokale Artikelnummer::
REST20999
Beschreibung:
Base-deactivated glass wool, ideal for amines and other basic compounds , Fiberglas, Weiß, 10 g
VE:
1 * 10 g
Lieferant:
Sigma-Aldrich
Beschreibung:
4-Aminopyridin, Sigma-Aldrich®
Lieferant:
Alfa Aesar
Beschreibung:
4-Aminopyridin ≥99%
Preis auf Anfrage
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